TBX1

General Information

Gene Name       : TBX1
Gene ID             : ENSG00000184058.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TBX1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TBX1ENSG00000184058.140.000.000.00ENCSR000AEF
HepG2TBX1ENSG00000184058.140.080.000.04ENCSR985KAT
K562TBX1ENSG00000184058.149.225.417.32ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TBX1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TBX1 RNA is bound by 20 proteins.  







eCLIP assay for TBX1 is not avaliable on ENCORE database.





20 proteins are bound to TBX1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr221975451019754574+3'-UTR,intron-Distal3.751575.72692K562HNRNPK
chr221975446019754517+3'-UTR,intron-Distal4.051205.38267K562DDX55
chr221975448519754574+3'-UTR,intron-Distal4.1086011.90847K562PCBP1
chr221975450619754664+3'-UTR,intron-Distal3.435193.24667K562FUS
chr221975471719754743+3'-UTR,intron-Distal3.561289.23696K562ZC3H11A
chr221975473819754844+3'-UTR,intron-Distal6.36883400.00000K562PUM2
chr221975438919754455+3'-UTR,intron-Distal4.073747.44326K562DDX55
chr221975469519754717+3'-UTR,intron-Distal3.406616.14837K562ZC3H11A
chr221975457419754648+3'-UTR,intron-Distal4.942747.08021K562HNRNPK
chr221975457419754646+3'-UTR,intron-Distal5.1393014.19589K562PCBP1
chr221975460219754647+3'-UTR,intron-Distal3.258723.92010K562DDX55
chr221975243119752490+CDS,intron-Proximal3.998199.73169K562SF3B4
chr221975164219751690+CDS,intron-Proximal4.4071528.93278K562AQR
chr221977043319770483+CDS,intron-Proximal3.651143.12654K562SLTM
chr221975263519752645+CDS,intron-Proximal5.3640446.45253K562AQR
chr221975085819750938+CDS,intron-Proximal3.408089.34032K562PRPF8
chr221975430319754388+CDS,intron-Distal3.917635.88499K562PUM1
chr221975169019751730+CDS3.7436816.93991K562AQR
chr221975078719750854+CDS3.217774.76953K562DDX24
chr221975086419750871+CDS,intron-Proximal5.4079231.89185K562AQR
chr221974852619748592+CDS3.864625.53232K562PUM1
chr221976405019764129+intron-Distal3.186683.01707K562SLTM
chr221975268719752739+intron-Distal,intron-Proximal4.8822027.59314K562AQR
chr221975270419752756+intron-Distal,intron-Proximal3.708728.15794K562BUD13
chr221975357319753630+intron-Distal,intron-Proximal3.780334.71867K562TIA1
chr221974829319748373+intron-Distal,intron-Proximal3.827034.15650K562PUM1
chr221975215919752213+intron-Distal3.838575.55667K562MTPAP
chr221976411919764215+intron-Distal3.130053.74491K562CSTF2T
chr221975099419751081+intron-Distal3.865106.17376K562HNRNPK
chr221975148619751548+intron-Distal3.153713.74491K562CSTF2T
chr221975216819752251+intron-Distal3.947388.13606K562UCHL5
chr221975216419752241+intron-Distal4.001554.26679K562GRWD1
chr221975275519752820+intron-Distal4.031393.83943K562HNRNPK
chr221975302219753104+intron-Distal4.280144.33150K562HNRNPK
chr221976232719762415+intron-Distal4.248673.36882K562SLTM
chr221975316919753273+intron-Distal,intron-Proximal3.799448.97396K562SF3B4
chr221974831519748386+intron-Distal,intron-Proximal4.786467.42659K562GEMIN5
chr221975506719755166+intron-Distal4.900067.66465K562HNRNPK
chr221975087119750951+intron-Proximal7.2772366.56331K562AQR
chr221975087019750932+intron-Proximal3.841509.43678K562BUD13
chr221975323119753262+intron-Proximal5.3099448.61721K562AQR
chr221975355319753607+intron-Proximal3.764933.07008K562NONO
chr221975267919752687+intron-Proximal5.3178813.75908K562AQR
chr221975319919753231+intron-Proximal4.7903444.10806K562AQR
chr221975185619751895+intron-Proximal4.7433624.22695K562AQR
chr221975264519752679+intron-Proximal5.6764059.99935K562AQR
chr221975184919751856+intron-Proximal3.9508814.60679K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TBX1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TBX1 is not available on ENCORE database.

  • 58 RBPs can affect the levels of TBX1.  








The Knockdown/knockout RNA-Seq assay for TBX1 is not available on ENCORE database.





58 RBPs can affect the gene expression of TBX1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TBX1ENSG00000184058.80.000007.81380-99999.999991.989001.44670HepG2HNRNPLL
TBX1ENSG00000184058.81381.64930488.764301.4991047.4374045.14230K562AGGF1
TBX1ENSG00000184058.8923.87650537.162500.782206.111504.50850K562AKAP8
TBX1ENSG00000184058.81520.64060508.602201.580006.071105.07900K562AKAP8L
TBX1ENSG00000184058.8218.34010369.87360-0.760504.123403.43500K562AQR
TBX1ENSG00000184058.81173.77290533.685401.137006.790205.27430K562ATP5C1
TBX1ENSG00000184058.8252.44050146.518800.784804.970003.66740K562BCLAF1
TBX1ENSG00000184058.8686.28320289.444701.245404.140502.79710K562CCAR1
TBX1ENSG00000184058.8252.36040111.156401.182805.225803.70860K562CSTF2
TBX1ENSG00000184058.8751.22480418.215600.8449013.2151010.57340K562DDX21
TBX1ENSG00000184058.8460.69390336.339200.453803.030901.93860K562DDX3X
TBX1ENSG00000184058.8500.92470341.003700.554704.952403.02200K562DDX6
TBX1ENSG00000184058.8684.40970324.130001.078203.363901.88230K562DHX30
TBX1ENSG00000184058.81109.03890547.162101.019205.788704.46340K562DKC1
TBX1ENSG00000184058.8195.76690351.39190-0.843906.474205.22620K562EIF4A3
TBX1ENSG00000184058.8458.81810316.447900.535904.588903.03420K562EIF4B
TBX1ENSG00000184058.8531.05940316.598800.746104.912703.17510K562EXOSC5
TBX1ENSG00000184058.8227.25000351.42210-0.628903.952002.92780K562FIP1L1
TBX1ENSG00000184058.8117.37540365.43290-1.6385021.5246019.94630K562FXR1
TBX1ENSG00000184058.8202.52770131.981300.617702.849701.39360K562G3BP1
TBX1ENSG00000184058.855.85830131.40040-1.234105.099004.07290K562G3BP2
TBX1ENSG00000184058.8838.23690658.393800.348302.449301.38130K562GLRX3
TBX1ENSG00000184058.81001.54720429.816501.220306.085704.01690K562HNRNPA2B1
TBX1ENSG00000184058.8128.64530325.55680-1.339502.087701.55960K562HNRNPC
TBX1ENSG00000184058.8203.69480289.02940-0.504802.150601.33520K562HNRNPM
TBX1ENSG00000184058.8987.68670462.247101.095304.519001.73080K562HNRNPUL1
TBX1ENSG00000184058.8353.85620476.48230-0.429302.389601.64650K562HSPD1
TBX1ENSG00000184058.8359.34230138.073801.379802.379901.44790K562IGF2BP2
TBX1ENSG00000184058.8219.58690140.427800.644903.345502.00090K562IGF2BP3
TBX1ENSG00000184058.8932.67010539.681200.789205.239104.03030K562KIF1C
TBX1ENSG00000184058.8224.64240145.080700.630702.403501.61740K562MAGOH
TBX1ENSG00000184058.8846.60550516.666800.712403.905502.55690K562MAK16
TBX1ENSG00000184058.81220.60730604.589401.013509.147407.30590K562MBNL1
TBX1ENSG00000184058.81019.80390769.106300.406905.487504.49060K562NSUN2
TBX1ENSG00000184058.8948.82420375.886401.335705.285703.79450K562PABPN1
TBX1ENSG00000184058.8173.49610308.87020-0.832105.946104.77630K562POLR2G
TBX1ENSG00000184058.8526.84570398.904300.401202.302601.55530K562PPIG
TBX1ENSG00000184058.8858.76660446.807200.942504.502802.47100K562PPP1R8
TBX1ENSG00000184058.8336.30030580.32290-0.787102.084201.37560K562PUF60
TBX1ENSG00000184058.8970.30440504.245200.944209.416308.46400K562PUS1
TBX1ENSG00000184058.8807.34120308.959601.385703.984601.64530K562RBFOX2
TBX1ENSG00000184058.81157.05350491.434101.2353024.5565022.71300K562RBM15
TBX1ENSG00000184058.81139.14830462.431701.300507.888804.96340K562RBM39
TBX1ENSG00000184058.8655.22780343.710800.930702.547301.41220K562SF1
TBX1ENSG00000184058.8621.81820758.92460-0.287502.215101.47910K562SF3A3
TBX1ENSG00000184058.8737.29040418.953400.815303.319301.84160K562SFPQ
TBX1ENSG00000184058.8691.26980394.803800.808003.250901.87670K562SNRNP200
TBX1ENSG00000184058.8606.22520305.189600.9900010.962808.74590K562SRSF4
TBX1ENSG00000184058.8264.18810130.516601.017207.015705.23350K562SRSF5
TBX1ENSG00000184058.8536.08280373.140300.522604.861803.29380K562SRSF7
TBX1ENSG00000184058.8210.79680309.83560-0.555702.882002.04400K562SYNCRIP
TBX1ENSG00000184058.8273.72870139.848500.968803.404802.61670K562TARDBP
TBX1ENSG00000184058.8264.41490134.901500.970806.823905.44900K562TIA1
TBX1ENSG00000184058.8249.11220132.395400.911802.557001.51350K562TRA2A
TBX1ENSG00000184058.8645.91060298.692701.112603.935802.76500K562TRIM56
TBX1ENSG00000184058.8682.14310815.50040-0.257602.059101.43370K562UPF1
TBX1ENSG00000184058.8526.47300725.63540-0.462905.303404.16850K562WDR43
TBX1ENSG00000184058.8581.44110416.610500.480803.592802.58500K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TBX1 is not available on ENCORE database.





1 RBPs can affect the splicing of TBX1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
MXETBX1ENSG00000184058.8chr22+19751677197518491975248019752636197507631975086519753280197533480.163000.001580.089711includedK562RBFOX2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TBX1 is not avaliable on ENCORE database.