SPG20

General Information

Gene Name       : SPG20
Gene ID             :
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SPG20)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SPG20 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SPG20 RNA is bound by 11 proteins.  







eCLIP assay for SPG20 is not avaliable on ENCORE database.





11 proteins are bound to SPG20 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr133687845636878593-3'-UTR,CDS,intron-Distal,intron-Proximal3.023138.13521K562UCHL5
chr133690994236909969-3'-UTR,5'-UTR,CDS,intron-Distal3.566134.20387K562ZNF622
chr133692054636920612-5'-UTR,intron-Distal4.569915.54639K562CSTF2T
chr133692055136920612-5'-UTR,intron-Distal3.977543.94684HepG2CSTF2T
chr133692076336920830-5'-UTR,intron-Distal3.909683.76710K562NONO
chr133690069136900833-CDS,intron-Distal,intron-Proximal5.204305.70640HepG2BCLAF1
chr133690349936903534-CDS,intron-Distal4.512844.55944K562ZNF622
chr133690968536909804-CDS,intron-Distal,intron-Proximal4.359804.45558HepG2GRWD1
chr133690077036900836-CDS,intron-Distal,intron-Proximal3.562956.44869K562UCHL5
chr133690349836903641-CDS,intron-Distal,intron-Proximal4.127824.21087HepG2GRWD1
chr133690921036909276-CDS,intron-Distal,intron-Proximal4.515335.16052K562RBM15
chr133688841736888471-CDS,intron-Distal4.735344.72754K562YBX3
chr133690349336903626-CDS,intron-Distal,intron-Proximal3.969145.79432HepG2BCLAF1
chr133690962636909715-CDS,intron-Distal,intron-Proximal5.244238.18798K562UCHL5
chr133690349836903650-CDS,intron-Distal,intron-Proximal3.123515.80673K562GRWD1
chr133688645636886507-CDS,intron-Distal,intron-Proximal3.426083.31745K562ZNF622
chr133690353436903603-CDS,intron-Distal3.255566.67170K562ZNF622
chr133690983436909890-CDS,intron-Distal4.579875.51215K562RBM15
chr133690971636909819-CDS,intron-Distal,intron-Proximal3.331789.46864K562UCHL5
chr133688836736888417-CDS,intron-Distal3.589923.87559K562YBX3
chr133690072036900832-CDS,intron-Distal,intron-Proximal5.6261011.96442K562ZNF622
chr133690349336903590-CDS,intron-Distal,intron-Proximal3.857098.13606K562UCHL5
chr133691288936913020-intron-Distal4.4186310.04921HepG2SUGP2
chr133691991836919998-intron-Distal3.851566.33374K562TIA1
chr133691302036913140-intron-Distal5.3730610.28828HepG2SUGP2
chr133691480836914854-intron-Distal3.839983.29248HepG2SUGP2
chr133691303736913143-intron-Distal4.7834012.68141K562TARDBP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SPG20 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SPG20 is not available on ENCORE database.

  • 67 RBPs can affect the levels of SPG20.  








The Knockdown/knockout RNA-Seq assay for SPG20 is not available on ENCORE database.





67 RBPs can affect the gene expression of SPG20 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SPG20ENSG00000133104.8374.27280507.89520-0.440403.758403.07040HepG2ACO1
SPG20ENSG00000133104.8559.83960735.66990-0.394001.975501.51640HepG2AKAP1
SPG20ENSG00000133104.8324.81540443.58640-0.449602.158501.33520HepG2BCCIP
SPG20ENSG00000133104.8295.09380405.54040-0.458702.901101.71650HepG2DDX1
SPG20ENSG00000133104.8294.93930436.14940-0.564403.040502.23590HepG2DDX55
SPG20ENSG00000133104.8314.51000605.32900-0.944608.040807.03990HepG2DDX6
SPG20ENSG00000133104.8289.90330397.66360-0.456003.056502.32190HepG2DNAJC21
SPG20ENSG00000133104.8310.48140394.11360-0.344102.291801.68610HepG2DNAJC2
SPG20ENSG00000133104.8435.67180643.17830-0.562003.600002.87320HepG2EIF4A3
SPG20ENSG00000133104.8629.06380841.16730-0.419204.349403.62550HepG2ETF1
SPG20ENSG00000133104.8504.76050648.85610-0.362301.905401.32650HepG2FXR1
SPG20ENSG00000133104.8399.26750601.95330-0.592303.990103.19940HepG2G3BP1
SPG20ENSG00000133104.8188.70140405.24500-1.102703.712102.52800HepG2GNB2L1
SPG20ENSG00000133104.8193.52760401.47290-1.052809.358608.27340HepG2HNRNPA1
SPG20ENSG00000133104.8301.06100446.55160-0.568803.573202.79330HepG2HNRNPC
SPG20ENSG00000133104.8433.79820556.03820-0.358202.529901.84300HepG2HNRNPF
SPG20ENSG00000133104.8389.55920609.42920-0.645605.023604.10290HepG2HNRNPK
SPG20ENSG00000133104.8506.60550632.37400-0.319902.745202.07410HepG2HNRNPL
SPG20ENSG00000133104.8312.65770722.06210-1.2075014.1339012.86240HepG2HNRNPLL
SPG20ENSG00000133104.8418.85220547.54250-0.386502.408301.73090HepG2IGF2BP1
SPG20ENSG00000133104.8441.34650611.88800-0.471402.816102.13590HepG2IGF2BP2
SPG20ENSG00000133104.8358.63610464.27410-0.372502.809601.78700HepG2KIF1C
SPG20ENSG00000133104.8610.80230427.228600.515602.732701.49240HepG2KRR1
SPG20ENSG00000133104.8486.86450668.11520-0.456602.633102.01390HepG2NCBP2
SPG20ENSG00000133104.8505.03080688.37410-0.446803.813402.91680HepG2NOL12
SPG20ENSG00000133104.8916.55320640.212600.517604.185403.27060HepG2NSUN2
SPG20ENSG00000133104.8351.55760595.05110-0.759306.242905.17050HepG2PABPC4
SPG20ENSG00000133104.8420.04150604.86690-0.526105.124304.42750HepG2PTBP1
SPG20ENSG00000133104.8445.79120697.54640-0.645909.439808.48130HepG2PUM1
SPG20ENSG00000133104.8398.26230517.32280-0.377302.969002.33680HepG2PUS1
SPG20ENSG00000133104.8504.19790655.11620-0.377802.819702.19010HepG2QKI
SPG20ENSG00000133104.8707.43270498.319100.505401.923601.32540HepG2RAVER1
SPG20ENSG00000133104.8232.96830361.22700-0.632803.251701.38880HepG2RBM14
SPG20ENSG00000133104.8376.94280594.54850-0.657406.104805.13830HepG2RBM25
SPG20ENSG00000133104.8507.42280673.17060-0.407803.557102.95960HepG2NELFE
SPG20ENSG00000133104.8351.28220598.93630-0.769807.284606.25450HepG2RPLP0
SPG20ENSG00000133104.8211.96490329.60120-0.636903.873503.15720HepG2RPS19
SPG20ENSG00000133104.8312.23040395.05320-0.339402.052301.48440HepG2SAFB2
SPG20ENSG00000133104.8526.98680689.35120-0.387501.914401.35100HepG2SF3A3
SPG20ENSG00000133104.8422.87270629.77010-0.574605.993305.17990HepG2SF3B4
SPG20ENSG00000133104.8314.62810460.71140-0.550205.229504.39360HepG2SMN1
SPG20ENSG00000133104.8516.25350794.09200-0.621208.628907.87870HepG2SRFBP1
SPG20ENSG00000133104.8882.25060657.333200.424503.556203.03660HepG2SRSF1
SPG20ENSG00000133104.8412.43760648.79470-0.653606.533705.62730HepG2SRSF5
SPG20ENSG00000133104.8428.21320546.27690-0.351302.374001.72540HepG2SRSF7
SPG20ENSG00000133104.8429.39280534.76660-0.316602.338601.82250HepG2SRSF9
SPG20ENSG00000133104.8995.52150689.472000.529907.833307.05570HepG2SSB
SPG20ENSG00000133104.8612.96620737.86280-0.267502.162601.60030HepG2SUCLG1
SPG20ENSG00000133104.8177.90630394.40580-1.148606.342504.95640HepG2SUPT6H
SPG20ENSG00000133104.8311.35600590.80770-0.9241012.2824011.23110HepG2TAF15
SPG20ENSG00000133104.8367.25090542.90250-0.563904.759603.67300HepG2TIA1
SPG20ENSG00000133104.8201.99450431.08840-1.0937012.6354011.70040HepG2TIAL1
SPG20ENSG00000133104.8755.68540499.517700.597205.385604.52510HepG2U2AF1
SPG20ENSG00000133104.8162.45150256.46020-0.658703.440002.59830HepG2UCHL5
SPG20ENSG00000133104.8300.08760672.36730-1.1639024.8036023.57530HepG2ZNF622
SPG20ENSG00000133104.81746.936601464.349900.254501.949001.39790K562AKAP8L
SPG20ENSG00000133104.83664.942702982.817700.297003.455302.36290K562CELF1
SPG20ENSG00000133104.81020.761001343.31940-0.396204.786103.87360K562EIF2S2
SPG20ENSG00000133104.8874.976501054.10440-0.268702.080101.38250K562EIF3G
SPG20ENSG00000133104.81641.332201278.124200.360702.009001.41880K562G3BP2
SPG20ENSG00000133104.8669.19290951.08860-0.507204.753803.99160K562HNRNPC
SPG20ENSG00000133104.81562.042101962.63900-0.329402.699201.91360K562HSPD1
SPG20ENSG00000133104.81950.946501553.998100.328102.794501.96440K562KIF1C
SPG20ENSG00000133104.82211.788901740.876400.345303.644302.57770K562MBNL1
SPG20ENSG00000133104.8646.96750852.73690-0.398402.664701.78000K562PSIP1
SPG20ENSG00000133104.81226.934801515.68370-0.304902.544201.90340K562PTBP1
SPG20ENSG00000133104.81811.689601452.145400.319002.465001.94580K562PUS1
SPG20ENSG00000133104.81926.171501414.969800.444905.396404.59360K562RBM15
SPG20ENSG00000133104.81196.412901485.80150-0.312502.696301.99720K562SRSF1
SPG20ENSG00000133104.81025.250901403.04490-0.452604.011202.70600K562SRSF5
SPG20ENSG00000133104.81018.073401450.62720-0.510805.295404.11160K562TIA1
SPG20ENSG00000133104.81147.599701423.12010-0.310402.274701.30610K562TRA2A
SPG20ENSG00000133104.81694.386801238.923200.451602.723501.64010K562U2AF1
SPG20ENSG00000133104.81769.050801279.536200.467306.118704.92960K562U2AF2
SPG20ENSG00000133104.82745.992002225.237300.303302.869901.55130K562WRN
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SPG20 is not available on ENCORE database.





1 RBPs can affect the splicing of SPG20 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESPG20ENSG00000133104.8chr13-3691042336910493369091573690996936920718369209340.207000.000210.00318includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SPG20 is not avaliable on ENCORE database.