SP140

General Information

Gene Name       : SP140
Gene ID             : ENSG00000079263.18
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SP140)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SP140ENSG00000079263.1890.4381.7786.10ENCSR000AEF
HepG2SP140ENSG00000079263.180.370.550.46ENCSR985KAT
K562SP140ENSG00000079263.180.000.330.17ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SP140 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SP140 RNA is bound by 5 proteins.  







eCLIP assay for SP140 is not avaliable on ENCORE database.





5 proteins are bound to SP140 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr2231223671231223748+3'-UTR,CDS,intron-Proximal3.296364.74755K562ZNF622
chr2231223678231223755+3'-UTR,CDS,intron-Proximal3.480333.57857HepG2BCLAF1
chr2231094426231094441+intron-Distal7.1046925.15291K562LSM11
chr2231211916231211973+intron-Distal4.951386.35761K562HNRNPM
chr2231198713231198778+intron-Distal4.296254.78128HepG2SUGP2
chr2231094441231094450+intron-Distal7.1046925.15291K562LSM11
chr2231196012231196096+intron-Distal3.920213.79098HepG2SUGP2
chr2231211842231211903+intron-Distal4.441185.16513HepG2HNRNPM
chr2231194995231195085+intron-Distal3.354876.28047HepG2SUGP2
chr2231196668231196720+intron-Distal3.957213.63454HepG2SUGP2
chr2231211920231211964+intron-Distal4.204804.31871HepG2HNRNPM
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SP140 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SP140 is not available on ENCORE database.

  • 56 RBPs can affect the levels of SP140.  








The Knockdown/knockout RNA-Seq assay for SP140 is not available on ENCORE database.





56 RBPs can affect the gene expression of SP140 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SP140ENSG00000079263.14109.7342020.688802.4070013.5208012.39150HepG2ACO1
SP140ENSG00000079263.1410.1763039.50720-1.956903.841802.68890HepG2ADAR
SP140ENSG00000079263.14129.7837015.754003.0422014.5019013.38300HepG2AKAP1
SP140ENSG00000079263.1460.9207017.468401.802104.843903.47770HepG2AKAP8
SP140ENSG00000079263.1457.6404020.783001.471603.882502.98610HepG2AKAP8L
SP140ENSG00000079263.14102.3229013.035902.9725013.6546012.03460HepG2ASCC1
SP140ENSG00000079263.14138.3277044.263301.643809.319808.18320HepG2AUH
SP140ENSG00000079263.14286.6378019.188203.9008019.9293017.93340HepG2CNOT7
SP140ENSG00000079263.1412.7052040.51370-1.673003.313602.19920HepG2YBX3
SP140ENSG00000079263.1479.0936015.093002.389607.917606.91040HepG2DDX3X
SP140ENSG00000079263.14149.1749031.651602.2366010.110908.74580HepG2DDX55
SP140ENSG00000079263.1478.7894012.960802.603708.860007.81970HepG2DDX6
SP140ENSG00000079263.147.1604038.36990-2.421904.847803.56720HepG2DHX30
SP140ENSG00000079263.1411.0586039.78260-1.847003.664302.86130HepG2DNAJC21
SP140ENSG00000079263.1414.2719039.42960-1.466102.896602.23150HepG2DNAJC2
SP140ENSG00000079263.1433.9780012.463901.446802.096601.57290HepG2EIF2S1
SP140ENSG00000079263.1459.1280018.249901.695903.912002.84640HepG2EIF3D
SP140ENSG00000079263.14102.8341039.712101.372603.799002.90870HepG2FIP1L1
SP140ENSG00000079263.1463.2210013.893202.185906.008705.01550HepG2FXR1
SP140ENSG00000079263.1487.7220022.960301.933707.526705.83260HepG2GNB2L1
SP140ENSG00000079263.1421.75970101.77990-2.225702.364801.76920HepG2GPKOW
SP140ENSG00000079263.1428.6242081.49360-1.509505.324904.37020HepG2HNRNPF
SP140ENSG00000079263.1411.4192097.12750-3.088403.292202.61140HepG2HNRNPLL
SP140ENSG00000079263.1466.2720027.396101.274303.252402.22850HepG2HNRNPM
SP140ENSG00000079263.1418.9686080.24880-2.080907.731306.57630HepG2IGF2BP1
SP140ENSG00000079263.1435.0770013.104901.420302.100801.50350HepG2IGF2BP2
SP140ENSG00000079263.1421.2474045.33160-1.093202.323801.64480HepG2ILF2
SP140ENSG00000079263.1454.0034019.009601.506203.165001.82370HepG2KRR1
SP140ENSG00000079263.1452.3052022.476001.218502.771501.63520HepG2LARP7
SP140ENSG00000079263.1464.9539019.099201.765803.437702.26690HepG2METAP2
SP140ENSG00000079263.1421.2725086.09850-2.017002.047401.39950HepG2NSUN2
SP140ENSG00000079263.1412.2604039.58250-1.690903.404202.59360HepG2PPIL4
SP140ENSG00000079263.143.4357027.25800-2.988004.779503.79400HepG2PRPF4
SP140ENSG00000079263.1490.2259011.285902.9989010.149809.22990HepG2PTBP1
SP140ENSG00000079263.1414.5450039.26340-1.432702.597401.94700HepG2PUM2
SP140ENSG00000079263.14128.7826021.140302.6068011.4169010.05730HepG2RAVER1
SP140ENSG00000079263.14980.5245042.478004.5287015.3391014.32000HepG2RBM22
SP140ENSG00000079263.1444.9921012.561001.840601.960101.48740HepG2NELFE
SP140ENSG00000079263.1493.6437017.759402.398509.809508.73940HepG2RPS19
SP140ENSG00000079263.1454.4880024.998301.124002.410301.65930HepG2RPS2
SP140ENSG00000079263.1482.3550025.511801.690605.744504.18140HepG2RPS5
SP140ENSG00000079263.1410.4827029.34740-1.485201.897001.33620HepG2SF3A3
SP140ENSG00000079263.148.1199096.15590-3.565803.746802.93770HepG2SF3B1
SP140ENSG00000079263.1433.0820011.752001.493002.150101.61910HepG2SF3B4
SP140ENSG00000079263.1414.2507035.48000-1.316002.237601.59560HepG2SLBP
SP140ENSG00000079263.14123.6319046.089501.423407.381206.40860HepG2SMN1
SP140ENSG00000079263.14337.51170106.983501.657403.753702.83780HepG2SNRNP70
SP140ENSG00000079263.14264.9728047.976302.4653029.1461027.96740HepG2SRFBP1
SP140ENSG00000079263.1464.8927012.265702.403306.912406.24730HepG2SRSF1
SP140ENSG00000079263.14116.5052036.540701.672705.602804.75770HepG2SRSF5
SP140ENSG00000079263.1461.350309.978202.620109.063508.16730HepG2SRSF9
SP140ENSG00000079263.14285.0846041.563302.7779037.0937035.27260HepG2SUCLG1
SP140ENSG00000079263.1433.9328011.022901.622102.655802.10550HepG2TAF15
SP140ENSG00000079263.1452.6959026.026401.017602.185201.55230HepG2UPF1
SP140ENSG00000079263.1463.9296023.248101.459303.790602.54820HepG2XRCC6
SP140ENSG00000079263.1415.138802.284002.728502.153601.45050K562GPKOW
SP140ENSG00000079263.1415.914301.511303.396402.744402.15000K562HNRNPC
SP140ENSG00000079263.1414.096201.041203.758802.870202.13830K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SP140 is not available on ENCORE database.





1 RBPs can affect the splicing of SP140 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESP140ENSG00000079263.14chr2+2310996522310997902310951252310952432311017972311019750.729000.001280.07250includedHepG2RBM22

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SP140 is not avaliable on ENCORE database.