PPWD1

General Information

Gene Name       : PPWD1
Gene ID             : ENSG00000113593.11
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: PPWD1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PPWD1ENSG00000113593.1139.9635.5537.75ENCSR000AEF
HepG2PPWD1ENSG00000113593.1118.3237.0927.71ENCSR985KAT
K562PPWD1ENSG00000113593.1133.6739.7636.72ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PPWD1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PPWD1 RNA is bound by 17 proteins.  







eCLIP assay for PPWD1 is not avaliable on ENCORE database.





17 proteins are bound to PPWD1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr56486570864865789+3'-UTR,5'-UTR,CDS3.368644.71162K562LIN28B
chr56486764364867724+3'-UTR,5'-UTR,CDS,intron-Proximal3.206664.81700HepG2U2AF2
chr56487896664879027+3'-UTR,CDS3.205207.01182K562ZNF622
chr56486570564865768+3'-UTR,5'-UTR,CDS3.422599.30684HepG2BCLAF1
chr56488314964883219+3'-UTR,CDS3.202325.71803K562UCHL5
chr56486576864865830+3'-UTR,5'-UTR,CDS,intron-Proximal5.546557.95223HepG2BCLAF1
chr56488308664883184+3'-UTR,CDS4.073113.99014HepG2PABPN1
chr56487529664875352+3'-UTR,CDS,intron-Proximal4.274834.34615K562LIN28B
chr56486540864865463+3'-UTR,5'-UTR,CDS,intron-Proximal3.320455.82046K562SF3B4
chr56487536464875412+3'-UTR,CDS3.857875.96588K562ZNF622
chr56487881064878886+3'-UTR,CDS,intron-Proximal3.574525.44908K562SF3B4
chr56487891164878966+3'-UTR,CDS3.959639.03438K562ZNF622
chr56488311264883182+3'-UTR,CDS3.957764.04622HepG2GRWD1
chr56485922664859369+5'-UTR,CDS,intron-Proximal4.740766.44930HepG2SRSF1
chr56485922264859339+5'-UTR,CDS,intron-Proximal4.1039115.17442K562UCHL5
chr56485925664859349+5'-UTR,CDS,intron-Proximal3.172135.24900K562SRSF1
chr56485960264859664+5'-UTR,CDS,intron-Distal,intron-Proximal4.2166614.35931K562U2AF2
chr56485960564859663+5'-UTR,CDS,intron-Distal,intron-Proximal4.650455.17144K562U2AF1
chr56485922264859296+5'-UTR,CDS5.1071810.26368HepG2GRWD1
chr56485960364859662+5'-UTR,CDS,intron-Distal,intron-Proximal4.397384.72775HepG2U2AF1
chr56486336064863401+5'-UTR,CDS,intron-Distal4.173845.36555HepG2BCLAF1
chr56485927364859338+5'-UTR,CDS,intron-Proximal4.622559.74753HepG2BCLAF1
chr56485959064859667+5'-UTR,CDS,intron-Distal,intron-Proximal5.5905620.70018HepG2U2AF2
chr56485929664859345+5'-UTR,CDS,intron-Proximal3.942576.91167HepG2GRWD1
chr56485916064859282+5'-UTR,CDS3.2560317.28822K562ZNF622
chr56485928264859337+5'-UTR,CDS,intron-Proximal3.7200711.58254K562ZNF622
chr56485951364859631+CDS,intron-Distal,intron-Proximal4.744928.98522K562QKI
chr56486222164862343+intron-Distal4.002903.59673K562HNRNPL
chr56487616264876256+intron-Distal4.441784.27660K562HNRNPL
chr56486099864861048+intron-Distal4.842908.36768K562KHSRP
chr56486842464868528+intron-Distal4.0111110.33353HepG2PTBP1
chr56486251664862657+intron-Distal5.0988613.25687HepG2PCBP2
chr56486255464862633+intron-Distal3.455413.91876HepG2U2AF2
chr56487307764873139+intron-Distal3.941975.35459K562KHSRP
chr56485954264859596+intron-Distal,intron-Proximal3.338827.02852K562KHSRP
chr56485996564860023+intron-Distal3.043903.55116K562KHSRP
chr56486002864860053+intron-Distal4.284944.10688K562KHSRP
chr56487554464875655+intron-Distal3.172985.36888K562KHSRP
chr56487515064875200+intron-Distal,intron-Proximal5.005238.49499K562KHSRP
chr56485945964859542+intron-Distal,intron-Proximal3.204156.17398K562KHSRP
chr56487437264874528+intron-Distal3.170906.17398K562KHSRP
chr56487303464873077+intron-Distal4.672605.19823K562KHSRP
chr56486094264860977+intron-Distal3.850565.78005K562KHSRP
chr56486865564868724+intron-Distal5.174029.22342HepG2QKI
chr56485942964859471+intron-Distal,intron-Proximal4.280863.15006K562RBM15
chr56486255164862642+intron-Distal5.4183010.55181HepG2PTBP1
chr56486097764860998+intron-Distal4.865207.83372K562KHSRP
chr56486840364868509+intron-Distal4.4618411.20756K562PTBP1
chr56486254264862651+intron-Distal5.073034.90095K562PTBP1
chr56487520064875239+intron-Distal,intron-Proximal4.450406.28383K562KHSRP
chr56487292164872991+intron-Proximal3.9690814.67526K562KHSRP
chr56485933964859391+intron-Proximal4.188318.07592K562UCHL5
chr56487906464879132+intron-Proximal4.231485.02888K562KHSRP
chr56485934664859405+intron-Proximal3.234714.15299K562GRWD1
chr56487293164872990+intron-Proximal4.305183.98488K562TIA1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PPWD1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PPWD1 is not available on ENCORE database.

  • 45 RBPs can affect the levels of PPWD1.  








The Knockdown/knockout RNA-Seq assay for PPWD1 is not available on ENCORE database.





45 RBPs can affect the gene expression of PPWD1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PPWD1ENSG00000113593.7603.12220449.999200.422402.680101.62430HepG2AATF
PPWD1ENSG00000113593.7517.17720710.75860-0.458702.941702.13290HepG2ASCC1
PPWD1ENSG00000113593.7635.22910940.26510-0.565805.307904.51300HepG2BOP1
PPWD1ENSG00000113593.7681.31010863.22110-0.341401.999201.40400HepG2CPSF6
PPWD1ENSG00000113593.7426.15400566.57970-0.410903.136502.05170HepG2YBX3
PPWD1ENSG00000113593.7774.70280947.70080-0.290803.135302.35330HepG2DAZAP1
PPWD1ENSG00000113593.7436.38710551.41340-0.337502.825802.16780HepG2DNAJC2
PPWD1ENSG00000113593.7554.00780750.96340-0.438802.523701.91250HepG2EIF4A3
PPWD1ENSG00000113593.7517.73270702.85840-0.441002.634901.98500HepG2G3BP1
PPWD1ENSG00000113593.7700.81280571.150500.295102.433201.50990HepG2HDGF
PPWD1ENSG00000113593.7580.46070724.88660-0.320602.065401.43370HepG2IGF2BP1
PPWD1ENSG00000113593.7571.61600757.92820-0.407002.441201.82440HepG2MAGOH
PPWD1ENSG00000113593.7753.91020939.73470-0.317902.713201.95760HepG2NOL12
PPWD1ENSG00000113593.7504.40360897.04130-0.8306010.980809.89980HepG2PUF60
PPWD1ENSG00000113593.7705.63680952.22810-0.432406.155105.34370HepG2PUM1
PPWD1ENSG00000113593.7725.27860951.54550-0.391703.583602.82570HepG2PUM2
PPWD1ENSG00000113593.71145.28800917.895000.319202.603801.76980HepG2RBM15
PPWD1ENSG00000113593.7725.79920918.56080-0.339803.127202.58520HepG2RBM22
PPWD1ENSG00000113593.7335.20230482.25060-0.524803.109502.46250HepG2RPS19
PPWD1ENSG00000113593.7451.04950552.71520-0.293302.063201.49380HepG2SAFB2
PPWD1ENSG00000113593.7523.55800644.57250-0.300002.556501.93370HepG2SMN1
PPWD1ENSG00000113593.7779.804001037.47780-0.411905.206304.57860HepG2SRFBP1
PPWD1ENSG00000113593.7706.17400885.67270-0.326703.173602.51040HepG2SRSF5
PPWD1ENSG00000113593.7594.07790910.16040-0.615505.803104.80930HepG2TARDBP
PPWD1ENSG00000113593.7438.76830603.11750-0.459003.685403.12580HepG2TIAL1
PPWD1ENSG00000113593.7493.84430608.45550-0.301102.331001.80460HepG2TRIM56
PPWD1ENSG00000113593.7406.46320303.042800.423502.065901.40940HepG2UCHL5
PPWD1ENSG00000113593.71144.640701498.79400-0.388905.113104.38030K562AGGF1
PPWD1ENSG00000113593.7820.268501047.06150-0.352203.758102.63110K562BCLAF1
PPWD1ENSG00000113593.71115.060501428.84450-0.357703.325702.46360K562CPSF6
PPWD1ENSG00000113593.71425.869801085.431600.393502.245101.61780K562G3BP2
PPWD1ENSG00000113593.71314.556801729.33390-0.395603.973203.06980K562GRSF1
PPWD1ENSG00000113593.7774.04870952.51940-0.299301.955101.44210K562HNRNPC
PPWD1ENSG00000113593.71030.883701331.59700-0.369303.235402.28590K562METAP2
PPWD1ENSG00000113593.71079.648901330.28370-0.301203.589202.67600K562MTPAP
PPWD1ENSG00000113593.71178.129401478.11390-0.327305.255704.27470K562NSUN2
PPWD1ENSG00000113593.7945.793701448.17330-0.614602.666901.69780K562PABPN1
PPWD1ENSG00000113593.71263.964101646.99390-0.381902.560601.77670K562PPIG
PPWD1ENSG00000113593.71078.84030857.373800.331402.288801.60390K562PRPF8
PPWD1ENSG00000113593.7650.45090853.99510-0.392802.128001.34550K562PSIP1
PPWD1ENSG00000113593.7894.063801208.74140-0.435104.554003.72260K562PTBP1
PPWD1ENSG00000113593.7922.317201159.21930-0.329802.418001.63530K562RBM22
PPWD1ENSG00000113593.7601.70480778.97530-0.372502.781001.78830K562RCC2
PPWD1ENSG00000113593.7728.24380980.16780-0.428602.712101.67710K562SRSF4
PPWD1ENSG00000113593.71072.83610870.045900.302202.407301.64150K562SYNCRIP
PPWD1ENSG00000113593.7856.808101199.30890-0.485204.312403.42230K562TARDBP
PPWD1ENSG00000113593.7923.738601156.84790-0.324602.679601.87540K562TIA1
PPWD1ENSG00000113593.7608.55380821.42290-0.432702.768001.83100K562TIAL1
PPWD1ENSG00000113593.7619.51940872.44960-0.493904.198402.98130K562TRIM56
PPWD1ENSG00000113593.7887.842401086.57490-0.291402.325901.59120K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PPWD1 is not available on ENCORE database.





7 RBPs can affect the splicing of PPWD1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPPWD1ENSG00000113593.7chr5+648676656486811364865704648658256487270564872896-0.131000.000230.00620excludedK562SRSF1
SEPPWD1ENSG00000113593.7chr5+648676656486811364865704648658256487270564872896-0.114000.003250.05306excludedK562SF3B4
SEPPWD1ENSG00000113593.7chr5+648676656486811364865704648658256487270564872896-0.123000.000430.08177excludedK562WDR3
SEPPWD1ENSG00000113593.7chr5+6485962964859666648591226485933364863339648634420.151000.000000.00006includedHepG2U2AF1
SEPPWD1ENSG00000113593.7chr5+6485962964859666648591226485933364863339648634420.116000.000000.00002includedHepG2U2AF2
SEPPWD1ENSG00000113593.7chr5+648676656486811364865704648658256487270564872896-0.079000.000520.00698excludedK562AQR
SEPPWD1ENSG00000113593.7chr5+648808106488092264878864648790466488182564882008-0.080000.000020.00039excludedK562AQR
SEPPWD1ENSG00000113593.7chr5+6485962964859666648591226485933364863339648634420.084000.006170.09477includedK562U2AF1
SEPPWD1ENSG00000113593.7chr5+648633396486344264859116648593336487270564872778-0.163000.002170.06061excludedK562UTP18
MXEPPWD1ENSG00000113593.7chr5+64865704648658256486766564868113648590656485933364872705648728960.125000.000000.000051includedK562AQR
MXEPPWD1ENSG00000113593.7chr5+64872705648727786487525064875446648591256485933364878864648790460.120000.000010.000161includedK562AQR
MXEPPWD1ENSG00000113593.7chr5+64872705648727786487525064875440648591256485933364878864648790460.058000.014430.084911includedK562AQR
MXEPPWD1ENSG00000113593.7chr5+64865676648658256486766564868113648654586486555964872705648728960.095000.001070.008591includedHepG2U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PPWD1 is not avaliable on ENCORE database.