NSMCE2

General Information

Gene Name       : NSMCE2
Gene ID             : ENSG00000156831.7
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: NSMCE2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878NSMCE2ENSG00000156831.737.5529.5833.56ENCSR000AEF
HepG2NSMCE2ENSG00000156831.714.5222.9918.75ENCSR985KAT
K562NSMCE2ENSG00000156831.742.4246.3344.38ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for NSMCE2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • NSMCE2 RNA is bound by 17 proteins.  







eCLIP assay for NSMCE2 is not avaliable on ENCORE database.





17 proteins are bound to NSMCE2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr8126194571126194696+3'-UTR,intron-Distal,intron-Proximal3.519558.95130K562KHSRP
chr8126163411126163459+3'-UTR,5'-UTR,CDS,intron-Proximal4.385593.45943HepG2BCLAF1
chr8126163459126163526+3'-UTR,CDS,intron-Proximal4.491344.34038HepG2BCLAF1
chr8126194402126194448+3'-UTR,CDS3.630113.57857HepG2BCLAF1
chr8126379070126379207+3'-UTR,CDS3.398814.70209K562YBX3
chr8126104112126104205+5'-UTR,intron-Proximal3.142316.06401HepG2NCBP2
chr8126329032126329081+intron-Distal5.9958613.04119K562PTBP1
chr8126288688126288768+intron-Distal4.663296.23638HepG2QKI
chr8126202400126202455+intron-Distal3.724573.76275K562PTBP1
chr8126213810126213863+intron-Distal3.978283.51329HepG2MATR3
chr8126225951126226073+intron-Distal4.141838.88010K562ILF3
chr8126182186126182251+intron-Distal3.999803.45817K562MATR3
chr8126328989126329032+intron-Distal4.893085.39854K562PTBP1
chr8126239177126239280+intron-Distal3.661615.84244HepG2HNRNPK
chr8126211518126211585+intron-Distal4.047333.62025K562MATR3
chr8126213139126213277+intron-Distal3.350194.26619K562MATR3
chr8126114733126114841+intron-Distal,intron-Proximal3.366173.54718K562PRPF8
chr8126225957126226026+intron-Distal6.8120670.71233K562PTBP1
chr8126190021126190106+intron-Distal3.944113.06015K562MATR3
chr8126211746126211834+intron-Distal4.385063.45817K562MATR3
chr8126202435126202576+intron-Distal3.082153.45713HepG2PTBP1
chr8126212902126213024+intron-Distal4.208503.59917K562EXOSC5
chr8126141060126141125+intron-Distal4.356234.17759HepG2QKI
chr8126211777126211839+intron-Distal4.068453.59909K562EXOSC5
chr8126126683126126725+intron-Distal3.682853.14791K562HNRNPL
chr8126328995126329090+intron-Distal4.677366.10195HepG2PTBP1
chr8126208005126208098+intron-Distal3.557524.76004K562KHSRP
chr8126212908126212983+intron-Distal3.297803.10961HepG2MATR3
chr8126297690126297772+intron-Distal4.330004.30850HepG2QKI
chr8126210907126210983+intron-Distal4.036023.51329HepG2MATR3
chr8126212916126213039+intron-Distal3.685054.08528HepG2SUGP2
chr8126214217126214268+intron-Distal3.801933.30664K562NONO
chr8126252786126252908+intron-Distal3.600605.44125K562PTBP1
chr8126225907126225957+intron-Distal7.0612323.95693K562PTBP1
chr8126126443126126488+intron-Distal4.087283.55640HepG2QKI
chr8126126725126126832+intron-Distal4.800388.11205K562HNRNPL
chr8126126679126126779+intron-Distal4.027907.41599HepG2HNRNPL
chr8126109214126109347+intron-Distal4.122133.06150K562KHSRP
chr8126217750126217825+intron-Distal4.406004.05848HepG2QKI
chr8126211539126211590+intron-Distal3.507734.28254HepG2MATR3
chr8126195883126195962+intron-Distal3.591097.28429K562TARDBP
chr8126189432126189492+intron-Distal3.058033.35050HepG2SUGP2
chr8126212852126212883+intron-Distal3.903793.01445K562EXOSC5
chr8126211531126211592+intron-Distal3.957213.86809HepG2SUGP2
chr8126225914126226029+intron-Distal6.5329845.04376HepG2PTBP1
chr8126209836126209893+intron-Distal5.097307.06230K562EXOSC5
chr8126202455126202515+intron-Distal4.100606.12189K562PTBP1
chr8126239338126239448+intron-Distal3.330003.35103HepG2QKI
chr8126190406126190475+intron-Distal3.779513.23532K562MATR3
chr8126214978126215053+intron-Distal4.999788.57760K562KHSRP
chr8126214141126214217+intron-Distal3.094413.38183K562NONO
chr8126205440126205565+intron-Distal4.043094.42851K562HNRNPL
chr8126196800126196897+intron-Distal3.724805.67631K562KHDRBS1
chr8126225950126226031+intron-Distal5.391346.57498HepG2PCBP2
chr8126211759126211834+intron-Distal4.270024.78128HepG2SUGP2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for NSMCE2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for NSMCE2 is not available on ENCORE database.

  • 56 RBPs can affect the levels of NSMCE2.  








The Knockdown/knockout RNA-Seq assay for NSMCE2 is not available on ENCORE database.





56 RBPs can affect the gene expression of NSMCE2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
NSMCE2ENSG00000156831.3628.81720424.300400.567503.393602.81290HepG2AKAP1
NSMCE2ENSG00000156831.3314.86090414.39100-0.396302.621501.95120HepG2AUH
NSMCE2ENSG00000156831.3181.59210284.39890-0.647203.369502.61840HepG2CPSF6
NSMCE2ENSG00000156831.3204.62320322.95930-0.658402.578801.63710HepG2DDX59
NSMCE2ENSG00000156831.3213.19210304.76470-0.515502.340201.41080HepG2DDX5
NSMCE2ENSG00000156831.3178.39060260.25740-0.544902.643201.68260HepG2DHX30
NSMCE2ENSG00000156831.3180.61790269.83170-0.579103.345802.57780HepG2DNAJC21
NSMCE2ENSG00000156831.3195.94100267.47000-0.449002.530901.90190HepG2DNAJC2
NSMCE2ENSG00000156831.3178.77670335.67370-0.908905.895305.04660HepG2EIF2S1
NSMCE2ENSG00000156831.3112.25040370.99700-1.7247015.7881014.27420HepG2EIF4A3
NSMCE2ENSG00000156831.3284.31130392.81220-0.466402.499701.72390HepG2EIF4G2
NSMCE2ENSG00000156831.3327.29650475.77350-0.539704.578603.84010HepG2ETF1
NSMCE2ENSG00000156831.3238.07990347.19080-0.544302.673902.01940HepG2G3BP1
NSMCE2ENSG00000156831.3260.76920368.50840-0.498902.451001.61500HepG2G3BP2
NSMCE2ENSG00000156831.3217.05180322.35920-0.570602.699202.06490HepG2GPKOW
NSMCE2ENSG00000156831.3200.12930272.41700-0.444901.842701.30260HepG2HNRNPA1
NSMCE2ENSG00000156831.3182.18850303.02050-0.734004.138903.30360HepG2HNRNPC
NSMCE2ENSG00000156831.3212.91120307.63590-0.531002.449201.85190HepG2HNRNPLL
NSMCE2ENSG00000156831.3197.20500301.01660-0.610104.214303.47960HepG2HNRNPU
NSMCE2ENSG00000156831.3210.55930352.93340-0.745204.504903.66140HepG2IGF2BP2
NSMCE2ENSG00000156831.3298.06410517.09240-0.794802.540401.74610HepG2LARP4
NSMCE2ENSG00000156831.3240.77570385.33190-0.678403.894203.14710HepG2NCBP2
NSMCE2ENSG00000156831.3250.72000343.23320-0.453102.004401.38160HepG2PABPC4
NSMCE2ENSG00000156831.3250.41060393.43910-0.651804.511503.77150HepG2PUF60
NSMCE2ENSG00000156831.3330.40230417.65140-0.338102.177401.63840HepG2PUM1
NSMCE2ENSG00000156831.3311.97300417.34730-0.419802.452801.82180HepG2PUM2
NSMCE2ENSG00000156831.3278.50270405.82630-0.543203.668102.96440HepG2QKI
NSMCE2ENSG00000156831.3400.43860253.266000.660802.648101.95820HepG2RAVER1
NSMCE2ENSG00000156831.3298.77160417.01990-0.481103.190502.61810HepG2NELFE
NSMCE2ENSG00000156831.3267.69290388.39440-0.536903.761403.05770HepG2RECQL
NSMCE2ENSG00000156831.3222.79410328.04940-0.558202.583701.92020HepG2RPLP0
NSMCE2ENSG00000156831.3282.65590390.12690-0.464902.935002.32970HepG2SF3B4
NSMCE2ENSG00000156831.3257.41140377.24350-0.551404.225403.38430HepG2SLBP
NSMCE2ENSG00000156831.3743.46720449.142500.7270010.343709.54210HepG2SRFBP1
NSMCE2ENSG00000156831.3242.73130388.46190-0.678405.810204.95220HepG2SRSF5
NSMCE2ENSG00000156831.3213.40090331.28300-0.634504.913104.21630HepG2SRSF9
NSMCE2ENSG00000156831.3301.94240389.96380-0.369102.233601.76150HepG2SSB
NSMCE2ENSG00000156831.3352.10470441.78980-0.327402.028901.48010HepG2SUCLG1
NSMCE2ENSG00000156831.3262.08940366.00910-0.481803.027402.44470HepG2TAF15
NSMCE2ENSG00000156831.3133.86100299.92690-1.163908.822207.63070HepG2TARDBP
NSMCE2ENSG00000156831.3200.59000292.46780-0.544003.088402.56490HepG2TIAL1
NSMCE2ENSG00000156831.3215.36640295.11030-0.454502.623602.07090HepG2TRIM56
NSMCE2ENSG00000156831.3249.28550384.37070-0.624704.121403.03270HepG2TUFM
NSMCE2ENSG00000156831.3446.59520300.269800.572603.172502.50230HepG2U2AF1
NSMCE2ENSG00000156831.3312.03620241.944300.366901.944901.36660HepG2ZC3H8
NSMCE2ENSG00000156831.3555.10410711.91080-0.358902.393801.78570K562AKAP8L
NSMCE2ENSG00000156831.3457.77960646.02610-0.496903.767803.08400K562HNRNPC
NSMCE2ENSG00000156831.3881.43450614.365800.520703.380902.34440K562HNRNPM
NSMCE2ENSG00000156831.3499.55010653.84780-0.388302.807301.87780K562MATR3
NSMCE2ENSG00000156831.3685.15280540.019700.343302.474901.72000K562POLR2G
NSMCE2ENSG00000156831.3641.12630424.861400.593504.591203.62580K562PRPF8
NSMCE2ENSG00000156831.3978.71530706.093800.470903.414802.82070K562PUS1
NSMCE2ENSG00000156831.3404.35840528.45880-0.386202.306801.40650K562RCC2
NSMCE2ENSG00000156831.3458.39070758.14100-0.725902.891501.54750K562SFPQ
NSMCE2ENSG00000156831.3365.12210500.96600-0.456302.635601.64220K562SRFBP1
NSMCE2ENSG00000156831.3429.49890589.29360-0.456302.451001.46980K562SRSF5
NSMCE2ENSG00000156831.3438.86010609.19320-0.473103.794302.81410K562TIA1
NSMCE2ENSG00000156831.3453.42340591.85690-0.384402.295901.44680K562TRIM56
NSMCE2ENSG00000156831.3384.44110540.24050-0.490803.855302.90720K562U2AF2
NSMCE2ENSG00000156831.3617.37520755.27070-0.290802.384701.71490K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for NSMCE2 is not available on ENCORE database.





17 RBPs can affect the splicing of NSMCE2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SENSMCE2ENSG00000156831.3chr8+126111695126111799126104094126104200126114292126114388-0.070000.001040.07911excludedHepG2G3BP1
SENSMCE2ENSG00000156831.3chr8+126111695126111799126104111126104200126114558126114729-0.195000.001140.02336excludedK562SRSF1
SENSMCE2ENSG00000156831.3chr8+126114292126114388126104085126104200126114558126114729-0.230000.000000.00001excludedK562SF3B4
SENSMCE2ENSG00000156831.3chr8+1261682411261683401261634121261635191261943441261946720.196000.000000.00058includedHepG2DDX59
SENSMCE2ENSG00000156831.3chr8+126111695126111799126104094126104200126114292126114388-0.060000.000040.00526excludedHepG2AKAP1
SENSMCE2ENSG00000156831.3chr8+126114292126114388126104120126104200126114558126114729-0.247000.000000.00000excludedK562AQR
SENSMCE2ENSG00000156831.3chr8+126114255126114388126104085126104200126114558126114729-0.337000.001340.09983excludedHepG2SRSF7
SENSMCE2ENSG00000156831.3chr8+126111695126111799126104111126104200126114292126114388-0.132000.000000.00006excludedK562DROSHA
SENSMCE2ENSG00000156831.3chr8+1261682411261683401261634121261635191261943441261946720.303000.000100.00805includedHepG2SFPQ
SENSMCE2ENSG00000156831.3chr8+1261116951261117991261041111261042001261142551261143880.100000.004320.07263includedK562U2AF1
SENSMCE2ENSG00000156831.3chr8+126114292126114388126104085126104200126114558126114729-0.100000.001790.03621excludedK562U2AF1
SENSMCE2ENSG00000156831.3chr8+1261116951261117991261041111261042001261142921261143880.148000.000230.00955includedHepG2SF3A3
SENSMCE2ENSG00000156831.3chr8+126111695126111799126104094126104200126114292126114388-0.066000.001590.08999excludedHepG2IGF2BP3
SENSMCE2ENSG00000156831.3chr8+126111695126111799126104111126104200126114292126114388-0.104000.000900.06049excludedK562HNRNPUL1
SENSMCE2ENSG00000156831.3chr8+1261116951261117991261041111261042001261142921261143880.065000.000440.01005includedK562U2AF2
SENSMCE2ENSG00000156831.3chr8+126114292126114388126104085126104200126114558126114729-0.112000.000670.01426excludedK562U2AF2
SENSMCE2ENSG00000156831.3chr8+1261682411261683401261634121261635191261943441261946720.118000.000220.07242includedHepG2XRN2
A3SSNSMCE2ENSG00000156831.3chr8+1261142551261143881261142921261143881261040851261042000.154000.000020.00021longerK562AQR
A5SSNSMCE2ENSG00000156831.3chr8+126104085126104200126104085126104142126114292126114388-0.139000.000090.09095shorterK562SMNDC1
MXENSMCE2ENSG00000156831.3chr8+126111695126111799126114558126114681126104111126104200126194464126194498-0.376000.001310.071012includedK562LARP4
MXENSMCE2ENSG00000156831.3chr8+126111695126111799126114255126114388126104111126104200126114558126114729-0.175000.001100.019462includedK562DROSHA
MXENSMCE2ENSG00000156831.3chr8+126111695126111799126114292126114388126104094126104200126114558126114729-0.136000.000010.000472includedK562DROSHA
MXENSMCE2ENSG00000156831.3chr8+1261116951261117991261142551261143881261041111261042001261145581261147290.071000.007530.083801includedK562U2AF1
MXENSMCE2ENSG00000156831.3chr8+126111695126111799126114255126114388126104111126104200126114558126114729-0.071000.001110.020672includedK562SRSF1
MXENSMCE2ENSG00000156831.3chr8+1261145581261147291261634121261635191261041111261042001261943441261944980.177000.000000.000001includedK562AQR
MXENSMCE2ENSG00000156831.3chr8+1261116951261117991261142551261143881261041111261042001261145581261147290.090000.001690.024271includedK562U2AF2
MXENSMCE2ENSG00000156831.3chr8+1261116951261117991261142921261143881261040941261042001261145581261147290.068000.000580.010201includedK562U2AF2
MXENSMCE2ENSG00000156831.3chr8+1261116951261117991261142921261143881261040941261042001261145581261147290.160000.000840.032221includedHepG2SF3A3
MXENSMCE2ENSG00000156831.3chr8+126111695126111799126114292126114388126104094126104200126114558126114729-0.105000.005890.069452includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for NSMCE2 is not avaliable on ENCORE database.