INPP5B

General Information

Gene Name : INPP5B
Gene ID : ENSG00000204084.12
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: INPP5B)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	INPP5B	ENSG00000204084.12	17.08	16.99	17.03	ENCSR000AEF
HepG2	INPP5B	ENSG00000204084.12	3.54	4.62	4.08	ENCSR985KAT
K562	INPP5B	ENSG00000204084.12	14.26	13.33	13.79	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for INPP5B is not avaliable on ENCORE database.

Proteins bound to RNA

INPP5B RNA is bound by 17 proteins.

eCLIP assay for INPP5B is not avaliable on ENCORE database.

17 proteins are bound to INPP5B RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr1	38326701	38326738	-	3'-UTR,intron-Distal	4.06201	3.45012	HepG2	UPF1
chr1	38327338	38327399	-	3'-UTR,intron-Distal	3.29290	13.14288	K562	UPF1
chr1	38397051	38397143	-	3'-UTR,intron-Distal	4.63902	6.08649	K562	CSTF2T
chr1	38326537	38326649	-	3'-UTR,intron-Distal	4.54260	24.06938	K562	AKAP1
chr1	38345711	38345768	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.12714	3.02181	K562	PRPF8
chr1	38343774	38343880	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.37839	3.88924	K562	PRPF8
chr1	38396887	38396985	-	3'-UTR,intron-Distal	4.03019	3.82910	K562	NONO
chr1	38326562	38326669	-	3'-UTR,intron-Distal	3.68256	6.78793	HepG2	UPF1
chr1	38397048	38397141	-	3'-UTR,intron-Distal	3.67580	5.85006	K562	NONO
chr1	38327346	38327387	-	3'-UTR,intron-Distal	4.08753	4.19989	HepG2	UPF1
chr1	38327493	38327529	-	3'-UTR,intron-Distal	3.50414	7.91779	K562	UPF1
chr1	38327022	38327104	-	3'-UTR,intron-Distal	6.08166	30.24250	K562	UPF1
chr1	38326382	38326461	-	3'-UTR,intron-Distal	7.46086	21.41887	K562	PUM2
chr1	38326901	38326978	-	3'-UTR,intron-Distal	3.56860	4.75351	K562	LIN28B
chr1	38326573	38326661	-	3'-UTR,intron-Distal	4.45518	3.37208	HepG2	ILF3
chr1	38327150	38327228	-	3'-UTR,intron-Distal	4.56933	16.00835	K562	AKAP1
chr1	38326531	38326665	-	3'-UTR,intron-Distal	5.33173	42.08966	K562	UPF1
chr1	38327142	38327216	-	3'-UTR,intron-Distal	5.46362	18.13060	K562	UPF1
chr1	38326560	38326670	-	3'-UTR,intron-Distal	3.04911	4.91867	K562	ILF3
chr1	38326692	38326749	-	3'-UTR,intron-Distal	3.66341	9.35802	K562	UPF1
chr1	38326749	38326798	-	3'-UTR,intron-Distal	3.33743	8.47743	K562	UPF1
chr1	38327483	38327552	-	3'-UTR,intron-Distal	4.07672	10.03858	K562	AKAP1
chr1	38326700	38326756	-	3'-UTR,intron-Distal	3.82981	12.25999	K562	AKAP1
chr1	38327660	38327711	-	3'-UTR,intron-Distal,intron-Proximal	3.58037	23.69843	K562	UPF1
chr1	38397377	38397451	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.23483	3.63902	HepG2	CSTF2T
chr1	38348462	38348544	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.12712	3.79199	HepG2	PPIG
chr1	38348473	38348525	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.35188	3.53690	K562	ZNF622
chr1	38352639	38352692	-	CDS,intron-Distal,intron-Proximal	4.12345	3.70678	K562	BUD13
chr1	38409263	38409313	-	CDS,intron-Distal,intron-Proximal	3.99211	4.98250	K562	AQR
chr1	38353911	38353999	-	CDS,intron-Distal,intron-Proximal	4.67403	5.86954	K562	UCHL5
chr1	38397232	38397276	-	CDS,intron-Distal,intron-Proximal	4.24783	3.87340	HepG2	CSTF2T
chr1	38348525	38348588	-	CDS,intron-Distal	3.22992	4.44630	K562	ZNF622
chr1	38338834	38338894	-	CDS,intron-Distal,intron-Proximal	6.08701	11.49904	K562	SF3B4
chr1	38357032	38357096	-	CDS,intron-Distal	4.00819	6.28735	K562	DDX24
chr1	38411467	38411522	-	CDS,intron-Distal	4.94677	4.48364	K562	DDX24
chr1	38334234	38334347	-	CDS,intron-Distal,intron-Proximal	4.17206	5.97994	K562	AQR
chr1	38353925	38354017	-	CDS,intron-Distal,intron-Proximal	3.90977	6.80284	K562	DDX24
chr1	38411495	38411579	-	CDS,intron-Distal,intron-Proximal	3.41313	3.94787	K562	AQR
chr1	38348555	38348631	-	CDS,intron-Distal,intron-Proximal	4.15307	4.98250	K562	AQR
chr1	38348488	38348598	-	CDS,intron-Distal,intron-Proximal	3.39585	6.11414	K562	BUD13
chr1	38334291	38334358	-	intron-Distal,intron-Proximal	3.18600	3.10102	HepG2	SF3B4
chr1	38388930	38389066	-	intron-Distal	4.51957	4.30178	K562	PTBP1
chr1	38351264	38351289	-	intron-Distal,intron-Proximal	4.99211	11.12698	K562	AQR
chr1	38351289	38351310	-	intron-Distal,intron-Proximal	4.77856	9.56266	K562	AQR
chr1	38341446	38341552	-	intron-Distal,intron-Proximal	3.32502	4.30679	K562	KHSRP
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for INPP5B is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for INPP5B is not available on ENCORE database.
44 RBPs can affect the levels of INPP5B.

The Knockdown/knockout RNA-Seq assay for INPP5B is not available on ENCORE database.

44 RBPs can affect the gene expression of INPP5B :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
INPP5B	ENSG00000204084.8	409.02270	540.27800	-0.40150	1.81630	1.37550	HepG2	AKAP1
INPP5B	ENSG00000204084.8	485.58030	310.20420	0.64640	3.64590	2.51190	HepG2	CCAR1
INPP5B	ENSG00000204084.8	370.83400	275.71980	0.42750	2.19240	1.58110	HepG2	DDX21
INPP5B	ENSG00000204084.8	308.45850	234.52130	0.39530	2.02650	1.41470	HepG2	DNAJC21
INPP5B	ENSG00000204084.8	744.04970	601.48750	0.30680	1.88820	1.37150	HepG2	ETF1
INPP5B	ENSG00000204084.8	196.21510	278.20280	-0.50370	2.51650	1.71910	HepG2	EWSR1
INPP5B	ENSG00000204084.8	377.66200	271.80270	0.47440	3.46320	2.37960	HepG2	HDGF
INPP5B	ENSG00000204084.8	330.12150	447.66110	-0.43940	2.28980	1.65080	HepG2	HNRNPK
INPP5B	ENSG00000204084.8	305.18280	205.97300	0.56710	2.63000	2.01390	HepG2	HNRNPLL
INPP5B	ENSG00000204084.8	318.10400	451.96820	-0.50670	2.32380	1.41760	HepG2	KHSRP
INPP5B	ENSG00000204084.8	388.24730	286.65870	0.43750	2.36420	1.61330	HepG2	MSI2
INPP5B	ENSG00000204084.8	332.59220	210.10300	0.66260	2.65930	1.71240	HepG2	MTPAP
INPP5B	ENSG00000204084.8	311.19210	456.02770	-0.55130	4.75710	3.99680	HepG2	PCBP1
INPP5B	ENSG00000204084.8	350.75620	464.01090	-0.40370	3.04000	2.47210	HepG2	PTBP1
INPP5B	ENSG00000204084.8	388.07840	289.97260	0.42030	2.85680	2.23360	HepG2	PUS1
INPP5B	ENSG00000204084.8	657.64320	502.56570	0.38790	2.75910	2.13510	HepG2	QKI
INPP5B	ENSG00000204084.8	379.58470	516.41150	-0.44410	3.32280	2.74140	HepG2	NELFE
INPP5B	ENSG00000204084.8	337.51850	483.12090	-0.51740	4.21610	3.51080	HepG2	SF3B4
INPP5B	ENSG00000204084.8	389.91560	226.83660	0.78140	3.84020	2.91300	HepG2	SNRNP70
INPP5B	ENSG00000204084.8	320.79360	567.80210	-0.82370	10.96060	10.14270	HepG2	SRFBP1
INPP5B	ENSG00000204084.8	361.12160	504.26320	-0.48170	3.92230	3.38330	HepG2	SRSF1
INPP5B	ENSG00000204084.8	325.75320	200.80510	0.69790	4.09330	3.23220	HepG2	TARDBP
INPP5B	ENSG00000204084.8	430.17960	254.21700	0.75880	6.76110	6.04150	HepG2	TIAL1
INPP5B	ENSG00000204084.8	408.60800	302.97580	0.43140	2.04860	1.49910	HepG2	U2AF1
INPP5B	ENSG00000204084.8	518.08690	359.92180	0.52540	5.00020	4.14210	HepG2	ZC3H8
INPP5B	ENSG00000204084.8	557.01490	355.30680	0.64860	8.04850	7.24200	HepG2	ZNF622
INPP5B	ENSG00000204084.8	957.45230	1305.64240	-0.44750	4.63810	2.96310	K562	APOBEC3C
INPP5B	ENSG00000204084.8	531.92600	685.14950	-0.36520	3.17430	1.74430	K562	DDX27
INPP5B	ENSG00000204084.8	754.30810	1155.27070	-0.61500	10.55420	9.37460	K562	DDX47
INPP5B	ENSG00000204084.8	330.42650	477.60000	-0.53150	2.19920	1.31550	K562	EIF3A
INPP5B	ENSG00000204084.8	526.87680	709.36610	-0.42910	3.81440	2.88920	K562	EIF3G
INPP5B	ENSG00000204084.8	662.75680	841.97400	-0.34530	2.89690	2.28010	K562	FXR1
INPP5B	ENSG00000204084.8	684.54000	1133.44720	-0.72750	9.23290	7.83020	K562	GRSF1
INPP5B	ENSG00000204084.8	733.66570	1080.46850	-0.55850	6.13530	4.86390	K562	MAGOH
INPP5B	ENSG00000204084.8	707.22120	872.37280	-0.30280	2.73620	1.93170	K562	MTPAP
INPP5B	ENSG00000204084.8	569.55590	765.06150	-0.42570	3.63240	2.70850	K562	POLR2G
INPP5B	ENSG00000204084.8	576.48190	732.38560	-0.34530	2.01580	1.37040	K562	PRPF8
INPP5B	ENSG00000204084.8	748.62320	1049.74930	-0.48770	5.23410	4.34400	K562	PTBP1
INPP5B	ENSG00000204084.8	1120.05110	1614.45170	-0.52750	5.75950	4.58740	K562	PUF60
INPP5B	ENSG00000204084.8	1309.38310	1682.53190	-0.36170	4.57920	3.33550	K562	PUM2
INPP5B	ENSG00000204084.8	463.28740	745.93320	-0.68710	5.42940	4.28180	K562	RPS19
INPP5B	ENSG00000204084.8	748.24250	975.59730	-0.38280	2.32960	1.41970	K562	RPS3
INPP5B	ENSG00000204084.8	767.30210	956.44440	-0.31790	2.70800	1.90170	K562	SF3A3
INPP5B	ENSG00000204084.8	432.80980	584.21190	-0.43280	2.23920	1.37460	K562	SF3B1
INPP5B	ENSG00000204084.8	579.79490	871.71200	-0.58830	7.02610	5.62470	K562	SF3B4
INPP5B	ENSG00000204084.8	731.81560	1029.11410	-0.49190	5.09520	4.13910	K562	SRSF1
INPP5B	ENSG00000204084.8	1036.17220	839.24290	0.30400	2.45240	1.69590	K562	U2AF2
INPP5B	ENSG00000204084.8	566.80360	914.48840	-0.69010	12.20030	10.57510	K562	WDR43
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for INPP5B is not available on ENCORE database.

13 RBPs can affect the splicing of INPP5B :

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	INPP5B	ENSG00000204084.8	chr1	-	38352244	38352330			38351309	38351497	38352559	38352676	0.29200	0.00000	0.00021	included	HepG2	HNRNPK
SE	INPP5B	ENSG00000204084.8	chr1	-	38407754	38407936			38406434	38406470	38409311	38409341	0.46300	0.00007	0.00945	included	HepG2	QKI
SE	INPP5B	ENSG00000204084.8	chr1	-	38352244	38352330			38351309	38351497	38352559	38352676	0.09300	0.00020	0.04463	included	K562	MTPAP
SE	INPP5B	ENSG00000204084.8	chr1	-	38335596	38335686			38334172	38334286	38338601	38338700	0.13800	0.00200	0.09301	included	HepG2	NCBP2
SE	INPP5B	ENSG00000204084.8	chr1	-	38349332	38349539			38348478	38348590	38351309	38351497	0.07900	0.00413	0.06219	included	K562	U2AF2
SE	INPP5B	ENSG00000204084.8	chr1	-	38348478	38348590			38345756	38345866	38351309	38351497	-0.12500	0.00408	0.06174	excluded	K562	U2AF2
A3SS	INPP5B	ENSG00000204084.8	chr1	-	38343859	38344164			38343859	38343995	38345756	38345866	0.32100	0.00005	0.00457	longer	K562	SF3B4
A3SS	INPP5B	ENSG00000204084.8	chr1	-	38334172	38334393			38334172	38334286	38338601	38338837	0.10100	0.00000	0.00000	longer	K562	AQR
A3SS	INPP5B	ENSG00000204084.8	chr1	-	38343859	38344164			38343859	38343995	38345756	38345959	0.22400	0.00152	0.01009	longer	K562	AQR
A3SS	INPP5B	ENSG00000204084.8	chr1	-	38343859	38344164			38343859	38343995	38345756	38345866	-0.21400	0.00006	0.04465	shorter	K562	HNRNPL
A3SS	INPP5B	ENSG00000204084.8	chr1	-	38343859	38344164			38343859	38343995	38345756	38345866	0.34600	0.00034	0.04474	longer	K562	HNRNPC
A5SS	INPP5B	ENSG00000204084.8	chr1	-	38397344	38397725			38397584	38397725	38357029	38357126	0.41100	0.00001	0.00242	longer	K562	TARDBP
A5SS	INPP5B	ENSG00000204084.8	chr1	-	38397344	38397725			38397584	38397725	38357029	38357126	0.68200	0.00026	0.01941	longer	HepG2	SRSF1
A5SS	INPP5B	ENSG00000204084.8	chr1	-	38397344	38397725			38397584	38397725	38357029	38357126	0.34500	0.00034	0.04223	longer	K562	PTBP1
A5SS	INPP5B	ENSG00000204084.8	chr1	-	38397344	38397725			38397584	38397725	38357029	38357126	0.44200	0.00000	0.00053	longer	K562	SRSF1
MXE	INPP5B	ENSG00000204084.8	chr1	-	38343859	38343995	38344028	38344164	38341277	38341388	38345756	38345866	0.10500	0.01531	0.08899	1included	K562	AQR
MXE	INPP5B	ENSG00000204084.8	chr1	-	38397584	38397725	38406359	38406470	38357029	38357126	38409311	38409341	0.38600	0.00251	0.06364	1included	K562	EFTUD2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

INPP5B

General Information

Functions

Localization

Domains (AlphaFold: INPP5B)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for INPP5B is not avaliable on ENCORE database.

17 proteins are bound to INPP5B RNA:

eCLIP assay for INPP5B is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for INPP5B is not available on ENCORE database.

44 RBPs can affect the gene expression of INPP5B :

The Knockdown/knockout RNA-Seq assay for INPP5B is not available on ENCORE database.

13 RBPs can affect the splicing of INPP5B :

The Knockdown/knockout RNA-Seq assay for INPP5B is not avaliable on ENCORE database.