DRG2

General Information

Gene Name       : DRG2
Gene ID             : ENSG00000108591.9
Essential Gene : No

Functions

Localization

Domains (AlphaFold: DRG2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878DRG2ENSG00000108591.912.1723.9618.07ENCSR000AEF
HepG2DRG2ENSG00000108591.927.1017.5122.30ENCSR985KAT
K562DRG2ENSG00000108591.925.1019.9522.52ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for DRG2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • DRG2 RNA is bound by 9 proteins.  







eCLIP assay for DRG2 is not avaliable on ENCORE database.





9 proteins are bound to DRG2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr171800373718003786+3'-UTR,CDS,intron-Distal,intron-Proximal5.459988.72621HepG2PRPF8
chr171800706918007122+3'-UTR,CDS,intron-Proximal4.478485.28859HepG2SF3B4
chr171801117818011258+3'-UTR3.595143.66308K562UPF1
chr171800234218002407+3'-UTR,CDS,intron-Distal,intron-Proximal3.756573.14999HepG2GRWD1
chr171800235718002407+3'-UTR,CDS,intron-Distal,intron-Proximal3.723454.41267HepG2PPIG
chr171800352718003621+3'-UTR,intron-Distal,intron-Proximal3.183193.72699HepG2PRPF4
chr171800485618004952+3'-UTR,CDS,intron-Distal,intron-Proximal4.223799.68077HepG2PRPF8
chr171800361918003664+3'-UTR,intron-Distal,intron-Proximal4.254754.57682HepG2SF3B4
chr171800302218003074+3'-UTR,CDS,intron-Distal,intron-Proximal3.9552812.49389HepG2PRPF8
chr171801077518010876+3'-UTR4.486235.17229HepG2UPF1
chr171800974618009798+3'-UTR,CDS,intron-Proximal4.173684.08604HepG2PPIG
chr171800299818003064+3'-UTR,CDS,intron-Distal,intron-Proximal3.173685.47500HepG2PPIG
chr171799720017997290+3'-UTR,CDS,intron-Proximal4.082724.21087HepG2GRWD1
chr171800706118007242+3'-UTR,CDS,intron-Proximal3.140995.71175HepG2BUD13
chr171800237718002439+3'-UTR,CDS,intron-Distal,intron-Proximal3.051035.11956HepG2PRPF8
chr171799128517991402+5'-UTR,CDS,intron-Proximal4.736756.76290HepG2GRWD1
chr171799126417991401+5'-UTR,CDS4.355624.10386HepG2NCBP2
chr171799130417991402+5'-UTR,CDS,intron-Proximal3.009633.55138K562ZNF622
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for DRG2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for DRG2 is not available on ENCORE database.

  • 34 RBPs can affect the levels of DRG2.  








The Knockdown/knockout RNA-Seq assay for DRG2 is not available on ENCORE database.





34 RBPs can affect the gene expression of DRG2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
DRG2ENSG00000108591.5504.90640388.623500.377502.900402.28040HepG2ACO1
DRG2ENSG00000108591.5383.17920245.174000.644104.126203.41160HepG2BOP1
DRG2ENSG00000108591.5444.57430359.446300.306502.117701.38100HepG2DDX19B
DRG2ENSG00000108591.5694.30590488.533100.507003.578402.79030HepG2HNRNPK
DRG2ENSG00000108591.5188.90580290.84010-0.622602.095601.33940HepG2PABPC1
DRG2ENSG00000108591.5184.99530324.47570-0.810603.382802.60490HepG2RAVER1
DRG2ENSG00000108591.51000.18190643.854300.635408.872808.06640HepG2RBM22
DRG2ENSG00000108591.5421.44210561.39940-0.413703.081802.51700HepG2NELFE
DRG2ENSG00000108591.5334.41840240.997900.472502.248001.60920HepG2SF3B1
DRG2ENSG00000108591.5460.02580331.329800.473302.272701.41420HepG2SMNDC1
DRG2ENSG00000108591.5418.84370309.946200.434302.652702.16130HepG2TIAL1
DRG2ENSG00000108591.5266.89110365.11800-0.452101.889101.35880HepG2U2AF1
DRG2ENSG00000108591.5343.32540238.339100.526502.507601.78540HepG2UCHL5
DRG2ENSG00000108591.5502.76830389.972700.366402.696402.00530HepG2UPF1
DRG2ENSG00000108591.5537.75830397.209300.437001.911601.30210HepG2XRN2
DRG2ENSG00000108591.5480.31110610.63890-0.346402.477801.93550K562AGGF1
DRG2ENSG00000108591.5531.50980683.76030-0.363403.069502.38730K562DDX47
DRG2ENSG00000108591.5217.57550361.10440-0.730903.189902.10290K562EIF3A
DRG2ENSG00000108591.5562.76160415.286100.438302.829401.99880K562EIF4A3
DRG2ENSG00000108591.5806.398901049.46250-0.380103.877302.76820K562EIF4G2
DRG2ENSG00000108591.5255.68930393.53150-0.622103.634002.31520K562FKBP4
DRG2ENSG00000108591.5209.09770289.22600-0.468002.044501.30550K562FMR1
DRG2ENSG00000108591.5625.56690431.875500.534405.013404.23300K562FXR1
DRG2ENSG00000108591.5124.97440264.52770-1.081806.537305.34900K562G3BP2
DRG2ENSG00000108591.5347.74690453.54020-0.383201.996101.47790K562HNRNPC
DRG2ENSG00000108591.5448.24820563.60540-0.330402.332001.58810K562MTPAP
DRG2ENSG00000108591.5436.49820699.13710-0.679605.391704.22520K562PCBP3
DRG2ENSG00000108591.5359.14790536.26980-0.578404.850903.78880K562POLR2G
DRG2ENSG00000108591.5604.58480459.232100.396602.559201.77560K562PPIG
DRG2ENSG00000108591.5965.045701217.96670-0.335802.904801.80940K562PUM1
DRG2ENSG00000108591.5975.160301193.32530-0.291302.612801.67950K562PUM2
DRG2ENSG00000108591.5463.91080630.13510-0.441802.653302.11800K562PUS1
DRG2ENSG00000108591.5606.48680431.026800.492603.138502.23740K562RBM22
DRG2ENSG00000108591.5168.94390250.78050-0.569902.874901.51370K562RBM25
DRG2ENSG00000108591.5165.99250256.28000-0.626602.886701.76650K562U2AF1
DRG2ENSG00000108591.5778.081801067.73430-0.456604.192803.09290K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for DRG2 is not available on ENCORE database.





16 RBPs can affect the splicing of DRG2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A5SSDRG2ENSG00000108591.5chr17+1800707818007267180070781800720318007936180079950.068000.000120.00293longerK562AQR
A5SSDRG2ENSG00000108591.5chr17+179971261799728717997126179972821800158318001673-0.273000.001170.08626shorterK562SF3B4
A5SSDRG2ENSG00000108591.5chr17+179971261799728717997126179972821800158318001673-0.523000.000010.00238shorterHepG2FTO
RIDRG2ENSG00000108591.5chr17+180029461800374918002946180030371800367618003749-0.115000.005790.09480excludedK562HNRNPC
RIDRG2ENSG00000108591.5chr17+1800233018003749180023301800239118002946180037490.333000.002250.01795includedHepG2U2AF2
RIDRG2ENSG00000108591.5chr17+1800294618003749180029461800303718003676180037490.307000.003010.02282includedHepG2U2AF2
RIDRG2ENSG00000108591.5chr17+1800233018003749180023301800239118002946180037490.227000.000750.02150includedHepG2UCHL5
RIDRG2ENSG00000108591.5chr17+180029461800374918002946180030371800367618003749-0.144000.001200.08467excludedK562AARS
RIDRG2ENSG00000108591.5chr17+1800233018003749180023301800239118002946180037490.264000.003740.03602includedHepG2U2AF1
RIDRG2ENSG00000108591.5chr17+1800294618003749180029461800303718003676180037490.232000.000240.00687includedHepG2G3BP1
RIDRG2ENSG00000108591.5chr17+1800294618003749180029461800303718003676180037490.272000.000040.00212includedHepG2KHSRP
RIDRG2ENSG00000108591.5chr17+1800294618003749180029461800303718003676180037490.393000.000000.00000includedHepG2NCBP2
RIDRG2ENSG00000108591.5chr17+1800233018003749180023301800240718002946180037490.125000.007020.04639includedHepG2SF3B4
RIDRG2ENSG00000108591.5chr17+180029461800374918002946180030371800367618003749-0.197000.001240.02194excludedHepG2SRSF9
RIDRG2ENSG00000108591.5chr17+1800294618003749180029461800303718003676180037490.195000.000210.00365includedHepG2HNRNPK
RIDRG2ENSG00000108591.5chr17+1800294618003749180029461800303718003676180037490.234000.000000.00002includedK562AQR
RIDRG2ENSG00000108591.5chr17+1800294618003749180029461800303718003676180037490.426000.000130.01987includedHepG2CDC40
MXEDRG2ENSG00000108591.5chr17+18002230180023911800294618003037180015831800167318003676180037490.098000.001320.025471includedK562PUS1
MXEDRG2ENSG00000108591.5chr17+1800158318001673180023301800239117997126179972871800294618003037-0.314000.004170.092852includedHepG2HNRNPU

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for DRG2 is not avaliable on ENCORE database.