DHX35

General Information

Gene Name       : DHX35
Gene ID             : ENSG00000101452.14
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: DHX35)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878DHX35ENSG00000101452.1413.8412.2313.04ENCSR000AEF
HepG2DHX35ENSG00000101452.1419.6520.3319.99ENCSR985KAT
K562DHX35ENSG00000101452.1415.0516.3115.68ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for DHX35 is not avaliable on ENCORE database.



Proteins bound to RNA
  • DHX35 RNA is bound by 17 proteins.  







eCLIP assay for DHX35 is not avaliable on ENCORE database.





17 proteins are bound to DHX35 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr203766803237668088+3'-UTR4.8741410.21308K562UPF1
chr203766783437667910+3'-UTR3.087533.47114HepG2UPF1
chr203765398937654034+3'-UTR,CDS,intron-Proximal4.073683.02181K562PRPF8
chr203763139937631448+3'-UTR,CDS,intron-Proximal3.660114.21358HepG2U2AF2
chr203765397437654043+3'-UTR,CDS,intron-Proximal3.492545.05395HepG2PRPF8
chr203766285037662887+3'-UTR,CDS3.970993.14999HepG2GRWD1
chr203766808837668144+3'-UTR4.491918.66095K562UPF1
chr203766784837667928+3'-UTR3.701496.40324K562UPF1
chr203765239937652479+3'-UTR,CDS,intron-Distal,intron-Proximal5.4115510.42975HepG2PRPF8
chr203765054537650577+3'-UTR,CDS3.042163.73413HepG2PPIG
chr203766288737662956+3'-UTR,CDS3.551575.74979HepG2GRWD1
chr203765396037654015+3'-UTR,CDS,intron-Proximal4.093083.31827HepG2GRWD1
chr203764351237643562+3'-UTR,CDS,intron-Proximal4.040373.35169HepG2U2AF2
chr203761745437617513+5'-UTR,CDS,intron-Proximal3.9281411.55292HepG2PPIG
chr203762349037623525+5'-UTR,CDS,intron-Proximal3.749687.10944HepG2PPIG
chr203761751337617560+5'-UTR,CDS3.283955.74131HepG2PPIG
chr203759099637591053+5'-UTR,CDS,intron-Proximal4.182888.63366HepG2NCBP2
chr203762351037623560+5'-UTR,CDS,intron-Proximal4.016274.45914HepG2PRPF8
chr203761746137617517+5'-UTR,CDS5.239255.34688K562DDX24
chr203761753537617594+5'-UTR,CDS,intron-Proximal4.7302611.50355HepG2PRPF8
chr203759784337597896+CDS,intron-Proximal3.460435.58816K562PRPF8
chr203761236737612397+CDS3.204059.44988HepG2PPIG
chr203759783437597896+CDS,intron-Proximal5.6426313.78100HepG2PRPF8
chr203759104737591099+CDS,intron-Proximal4.743364.65563K562AQR
chr203761234237612430+CDS,intron-Proximal4.283367.87148HepG2PRPF8
chr203759772337597758+CDS,intron-Proximal4.216854.36077HepG2NCBP2
chr203761239737612421+CDS,intron-Proximal3.9482310.42618HepG2PPIG
chr203762631237626415+intron-Distal4.497115.44904K562TARDBP
chr203763583937635966+intron-Distal4.246257.29258HepG2SUGP2
chr203760917137609191+intron-Distal5.8496111.33566HepG2BCCIP
chr203763638337636428+intron-Distal4.138504.03915HepG2SUGP2
chr203760917137609194+intron-Distal5.244194.90578HepG2HNRNPM
chr203760919437609202+intron-Distal5.244194.90578HepG2HNRNPM
chr203760754537607637+intron-Distal3.153053.10883HepG2SUGP2
chr203761124937611341+intron-Distal5.087327.61882HepG2PCBP2
chr203765243337652603+intron-Distal,intron-Proximal4.5229210.18833HepG2EFTUD2
chr203763758837637646+intron-Distal4.703895.97584HepG2MATR3
chr203763449537634628+intron-Distal4.354394.80665HepG2QKI
chr203762785137627940+intron-Distal3.875843.23532K562MATR3
chr203765241037652418+intron-Distal,intron-Proximal4.492114.09264K562AQR
chr203763751937637588+intron-Distal4.536025.01910HepG2MATR3
chr203763781437637888+intron-Distal3.453773.59523HepG2SUGP2
chr203763533537635424+intron-Distal3.937197.29258HepG2SUGP2
chr203763720937637263+intron-Distal4.177503.79098HepG2SUGP2
chr203765241837652476+intron-Distal,intron-Proximal5.286596.83960K562AQR
chr203762874437628797+intron-Distal3.214503.10640HepG2SUGP2
chr203762795237628030+intron-Distal4.628653.27829HepG2MATR3
chr203763583837635917+intron-Distal4.300213.62238HepG2MATR3
chr203760919137609202+intron-Distal5.8496111.33566HepG2BCCIP
chr203762787037628032+intron-Distal3.356445.50064HepG2PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for DHX35 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for DHX35 is not available on ENCORE database.

  • 59 RBPs can affect the levels of DHX35.  








The Knockdown/knockout RNA-Seq assay for DHX35 is not available on ENCORE database.





59 RBPs can affect the gene expression of DHX35 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
DHX35ENSG00000101452.10794.04490563.269000.495303.062202.07010HepG2ABCF1
DHX35ENSG00000101452.10687.58090569.455600.271802.119001.57270HepG2ACO1
DHX35ENSG00000101452.10248.32990488.23350-0.975309.485108.46150HepG2BOP1
DHX35ENSG00000101452.10877.52810656.058200.419502.229201.36190HepG2CCAR1
DHX35ENSG00000101452.10536.01940727.72350-0.441102.662202.04720HepG2DDX3X
DHX35ENSG00000101452.10316.44470604.19130-0.933108.098406.85590HepG2DDX55
DHX35ENSG00000101452.10302.09910469.80050-0.637004.591603.30450HepG2DDX5
DHX35ENSG00000101452.10355.16180500.69610-0.495502.546701.49040HepG2AGO1
DHX35ENSG00000101452.10430.20830600.95360-0.482202.927102.31760HepG2EIF2S1
DHX35ENSG00000101452.101017.10120664.145700.614804.939804.08900HepG2EIF4A3
DHX35ENSG00000101452.10576.85210837.78680-0.538406.512805.32460HepG2EIF4G1
DHX35ENSG00000101452.10569.01460409.671500.473903.334702.47530HepG2FUBP3
DHX35ENSG00000101452.10365.38410508.07060-0.475602.523201.90920HepG2GPKOW
DHX35ENSG00000101452.10533.31520780.42660-0.549306.225104.92020HepG2HNRNPA2B1
DHX35ENSG00000101452.10547.83010693.77580-0.340702.797502.07640HepG2HNRNPF
DHX35ENSG00000101452.101133.44940629.332400.8487010.910309.60310HepG2HNRNPK
DHX35ENSG00000101452.10533.42740683.17230-0.357002.528701.83610HepG2IGF2BP1
DHX35ENSG00000101452.10881.72850670.264200.395502.450701.83230HepG2MAGOH
DHX35ENSG00000101452.10403.61470629.04220-0.640203.117702.17210HepG2PABPC1
DHX35ENSG00000101452.10780.09190613.231700.347103.167702.52620HepG2PCBP1
DHX35ENSG00000101452.10489.67920803.80580-0.715007.819106.88420HepG2PUF60
DHX35ENSG00000101452.10705.43090580.018200.282302.286401.71350HepG2PUS1
DHX35ENSG00000101452.10964.72210675.787400.513405.622704.77840HepG2QKI
DHX35ENSG00000101452.10551.83230747.34980-0.437603.053502.34140HepG2RPLP0
DHX35ENSG00000101452.10799.36500649.646500.299102.380901.82680HepG2SF3B4
DHX35ENSG00000101452.101014.54150678.093900.581207.495306.80580HepG2SRSF1
DHX35ENSG00000101452.10562.67040681.60800-0.276701.996601.39470HepG2SRSF7
DHX35ENSG00000101452.10222.73060379.90770-0.770303.812802.37990HepG2STAU1
DHX35ENSG00000101452.10956.89980609.507000.650609.117408.19560HepG2TAF15
DHX35ENSG00000101452.10425.84030540.97670-0.345302.552402.00630HepG2TRIM56
DHX35ENSG00000101452.10849.36660552.402900.620605.243204.46300HepG2UTP3
DHX35ENSG00000101452.10409.08650558.48640-0.449104.132403.33640HepG2ZC3H8
DHX35ENSG00000101452.10568.38170441.060900.365802.850002.27420K562AGGF1
DHX35ENSG00000101452.10627.05250458.951300.450103.344802.62560K562AKAP8L
DHX35ENSG00000101452.10497.46140788.55310-0.664606.067805.25640K562AQR
DHX35ENSG00000101452.10506.47250648.26990-0.356102.610201.34540K562BCCIP
DHX35ENSG00000101452.10203.20510382.92390-0.914106.844705.45240K562BOP1
DHX35ENSG00000101452.10416.58730549.33240-0.399103.149801.72680K562DDX27
DHX35ENSG00000101452.10363.00720486.93960-0.423702.688001.66070K562DDX3X
DHX35ENSG00000101452.10741.70030493.817600.586807.277905.74450K562DKC1
DHX35ENSG00000101452.10348.91440499.19830-0.516703.255902.26020K562EFTUD2
DHX35ENSG00000101452.10378.64420646.04910-0.7708010.109308.86600K562EIF2S2
DHX35ENSG00000101452.10200.81400304.08010-0.598602.292301.38560K562EIF3A
DHX35ENSG00000101452.10385.24570534.48430-0.472402.441601.47610K562EIF3D
DHX35ENSG00000101452.10428.89220529.06640-0.302801.824401.31250K562FXR1
DHX35ENSG00000101452.10277.45620388.73580-0.486502.730301.94090K562GPKOW
DHX35ENSG00000101452.10599.75820860.88890-0.521404.876103.87410K562GRSF1
DHX35ENSG00000101452.10346.71080470.25980-0.439702.593202.01260K562HNRNPC
DHX35ENSG00000101452.10608.21400752.94190-0.308002.287301.47350K562HNRNPU
DHX35ENSG00000101452.10706.92270487.035800.537402.992502.13290K562KIF1C
DHX35ENSG00000101452.10691.70750382.433200.854906.363304.81680K562NAA15
DHX35ENSG00000101452.10286.79990515.07280-0.844706.861905.55050K562PCBP3
DHX35ENSG00000101452.10230.59420395.07510-0.776806.504705.28380K562POLR2G
DHX35ENSG00000101452.10307.15220485.77750-0.661304.506403.55010K562PRPF8
DHX35ENSG00000101452.10417.52450550.35690-0.398502.770902.10610K562PTBP1
DHX35ENSG00000101452.10567.012101123.60790-0.9867014.9059012.98740K562PUF60
DHX35ENSG00000101452.10916.906601170.98900-0.352903.689502.57980K562PUM2
DHX35ENSG00000101452.10698.39110455.100300.617803.606002.99790K562PUS1
DHX35ENSG00000101452.10644.08710443.471000.538305.289204.49320K562RBM15
DHX35ENSG00000101452.10398.94010555.35490-0.477203.133401.96270K562NELFE
DHX35ENSG00000101452.10270.64310494.81490-0.870506.648505.37320K562RPS19
DHX35ENSG00000101452.10354.28720592.70410-0.742405.992504.07510K562STAU1
DHX35ENSG00000101452.10337.43610546.04490-0.694405.769804.72560K562TARDBP
DHX35ENSG00000101452.10370.20520488.62810-0.400402.638201.85280K562U2AF2
DHX35ENSG00000101452.10323.32970497.79020-0.622504.290402.99510K562UCHL5
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for DHX35 is not available on ENCORE database.





10 RBPs can affect the splicing of DHX35 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEDHX35ENSG00000101452.10chr20+376523323765241037650483376505783765387237654002-0.183000.006580.09115excludedK562SF3B4
SEDHX35ENSG00000101452.10chr20+376200963762015837617455376175603762099837621068-0.200000.000790.01693excludedHepG2U2AF1
SEDHX35ENSG00000101452.10chr20+376012013760129437597723375978573761234137612419-0.256000.000930.02981excludedK562AKAP8L
SEDHX35ENSG00000101452.10chr20+376200963762015837617455376175603762099837621068-0.100000.000160.00290excludedHepG2U2AF2
SEDHX35ENSG00000101452.10chr20+376012013760129437597723375978573761234137612419-0.327000.000040.00103excludedK562PUS1
SEDHX35ENSG00000101452.10chr20+376570603765714237653872376540023765934637659418-0.106000.001070.03230excludedHepG2SF3A3
SEDHX35ENSG00000101452.10chr20+376012013760129437597723375978573761234137612419-0.281000.003310.08224excludedK562UTP18
SEDHX35ENSG00000101452.10chr20+376012013760129437597723375978573761234137612419-0.361000.000050.00253excludedK562RBM15
SEDHX35ENSG00000101452.10chr20+376012013760129437597723375978573761234137612419-0.338000.000370.01268excludedK562AGGF1
SEDHX35ENSG00000101452.10chr20+376570603765714237653872376540023765934637659418-0.119000.004590.06497excludedK562HNRNPC
MXEDHX35ENSG00000101452.10chr20+37653872376540023765706037657142376505153765057837659346376594180.109000.000330.016021includedHepG2SF3A3

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for DHX35 is not avaliable on ENCORE database.