DCTN3

General Information

Gene Name       : DCTN3
Gene ID             : ENSG00000137100.15
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: DCTN3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878DCTN3ENSG00000137100.1516.9739.3328.15ENCSR000AEF
HepG2DCTN3ENSG00000137100.1533.2026.4329.82ENCSR985KAT
K562DCTN3ENSG00000137100.1533.9328.1931.06ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for DCTN3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • DCTN3 RNA is bound by 3 proteins.  







eCLIP assay for DCTN3 is not avaliable on ENCORE database.





3 proteins are bound to DCTN3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr93461358634613637-3'-UTR,intron-Distal,intron-Proximal3.134623.69775K562YBX3
chr93461607434616111-3'-UTR,CDS,intron-Distal,intron-Proximal3.964647.40140K562YBX3
chr93461358734613676-3'-UTR,intron-Distal,intron-Proximal3.430703.01032HepG2LARP4
chr93462040734620488-5'-UTR,CDS,intron-Distal,intron-Proximal3.9698210.73364K562DDX3X
chr93462036434620407-CDS,intron-Distal3.667694.72521K562DDX3X
chr93461788034617899-CDS,intron-Distal,intron-Proximal3.030333.26789K562YBX3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for DCTN3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for DCTN3 is not available on ENCORE database.

  • 54 RBPs can affect the levels of DCTN3.  








The Knockdown/knockout RNA-Seq assay for DCTN3 is not available on ENCORE database.





54 RBPs can affect the gene expression of DCTN3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
DCTN3ENSG00000137100.11534.47390308.952500.790605.344804.63490HepG2AKAP1
DCTN3ENSG00000137100.11444.47790242.865500.871906.849605.66840HepG2CIRBP
DCTN3ENSG00000137100.11274.71090191.333400.521703.398302.48620HepG2DDX19B
DCTN3ENSG00000137100.11275.28300163.526800.751304.384303.54980HepG2DDX21
DCTN3ENSG00000137100.11431.53850295.943900.544102.960102.31560HepG2DDX3X
DCTN3ENSG00000137100.11295.74660197.939600.579203.466802.72080HepG2DKC1
DCTN3ENSG00000137100.11104.83020152.52520-0.541001.949301.34820HepG2DNAJC21
DCTN3ENSG00000137100.11216.85690137.404400.658202.461301.59000HepG2EEF2
DCTN3ENSG00000137100.11426.41830270.068200.658803.894103.14010HepG2EIF4A3
DCTN3ENSG00000137100.11145.90710262.96920-0.849803.770302.97330HepG2EIF4B
DCTN3ENSG00000137100.11364.13150272.519000.418001.887801.31170HepG2FXR1
DCTN3ENSG00000137100.11254.32770169.779900.582902.477801.51850HepG2GNB2L1
DCTN3ENSG00000137100.11276.76690171.276800.692203.528902.75350HepG2HNRNPC
DCTN3ENSG00000137100.11430.79440280.588200.618403.606502.88760HepG2NCBP2
DCTN3ENSG00000137100.11209.43680308.97720-0.561003.764403.07940HepG2PCBP1
DCTN3ENSG00000137100.11241.47740145.892600.726903.106102.25480HepG2PRPF8
DCTN3ENSG00000137100.11244.77310314.37440-0.361001.776001.31820HepG2PTBP1
DCTN3ENSG00000137100.11291.09210210.740400.465902.729902.11750HepG2PUS1
DCTN3ENSG00000137100.11173.00490340.52100-0.976908.476107.47330HepG2QKI
DCTN3ENSG00000137100.11451.36630359.532000.328101.768601.33050HepG2RBM22
DCTN3ENSG00000137100.11306.63000213.814600.520002.276901.66450HepG2SF3A3
DCTN3ENSG00000137100.11225.86620327.34280-0.535303.405402.75780HepG2SF3B4
DCTN3ENSG00000137100.11300.73790406.07450-0.433202.985002.47090HepG2SRFBP1
DCTN3ENSG00000137100.11158.99990277.94460-0.805806.318905.54480HepG2SRSF9
DCTN3ENSG00000137100.11203.34650307.05320-0.594503.681903.05050HepG2TAF15
DCTN3ENSG00000137100.11330.89550165.344301.000808.796107.99510HepG2TIAL1
DCTN3ENSG00000137100.11297.24910185.366400.681203.023402.26640HepG2XRN2
DCTN3ENSG00000137100.11240.87280152.717800.657302.906802.22130HepG2ZC3H8
DCTN3ENSG00000137100.11316.10880208.547200.599904.458203.80670HepG2ZNF622
DCTN3ENSG00000137100.11918.01810556.313600.7225012.0453010.95370K562AGGF1
DCTN3ENSG00000137100.11927.82500611.342500.601806.596004.91720K562AKAP8
DCTN3ENSG00000137100.11805.45450578.878900.476404.125503.32540K562AKAP8L
DCTN3ENSG00000137100.111411.50210634.387401.1537020.5888019.16140K562AQR
DCTN3ENSG00000137100.11418.26800278.647600.585902.839101.54220K562EEF2
DCTN3ENSG00000137100.11519.05580269.150100.947407.712006.11980K562EFTUD2
DCTN3ENSG00000137100.11532.90080422.399600.335202.155401.50710K562EIF2S2
DCTN3ENSG00000137100.11430.32720284.436800.597204.112903.06540K562FIP1L1
DCTN3ENSG00000137100.11142.80060224.27450-0.651302.693101.99760K562G3BP2
DCTN3ENSG00000137100.11729.95000562.822000.375002.309901.61550K562GRSF1
DCTN3ENSG00000137100.11580.53700362.946400.677502.626401.44910K562HNRNPA2B1
DCTN3ENSG00000137100.11467.92000328.910300.508502.634501.64130K562IGF2BP2
DCTN3ENSG00000137100.11464.78260334.499600.474503.182701.88040K562IGF2BP3
DCTN3ENSG00000137100.11863.82920614.302400.491704.550603.45120K562KIF1C
DCTN3ENSG00000137100.11819.48940588.065100.478604.098402.71070K562MAK16
DCTN3ENSG00000137100.11694.90110482.366100.526603.075602.13780K562NAA15
DCTN3ENSG00000137100.11701.41080317.463201.143606.536104.81450K562PABPN1
DCTN3ENSG00000137100.11368.63950271.662700.440302.514701.75340K562POLR2G
DCTN3ENSG00000137100.11421.79230322.913200.385302.067301.36130K562PPIG
DCTN3ENSG00000137100.11560.32620261.917401.0971010.757509.26440K562PRPF8
DCTN3ENSG00000137100.11635.70040792.74180-0.318502.313001.34530K562PUM1
DCTN3ENSG00000137100.111185.81250574.022201.0466015.5350014.28750K562PUS1
DCTN3ENSG00000137100.11819.73810559.353500.551306.366205.49280K562RBM15
DCTN3ENSG00000137100.11539.90970290.321300.895003.245801.91500K562SF1
DCTN3ENSG00000137100.11562.08250333.427100.753302.764101.53560K562SNRNP200
DCTN3ENSG00000137100.11499.09140333.091600.583302.698001.99850K562TARDBP
DCTN3ENSG00000137100.11443.19170321.311800.463902.978902.12550K562TIA1
DCTN3ENSG00000137100.11427.40600315.368600.438502.472601.45260K562TRA2A
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for DCTN3 is not available on ENCORE database.





16 RBPs can affect the splicing of DCTN3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEDCTN3ENSG00000137100.11chr9-346160263461611034614706346147653461788134617968-0.259000.000010.00031excludedK562SF3B4
SEDCTN3ENSG00000137100.11chr9-346160263461611034614706346147653461788134617968-0.184000.000050.00358excludedK562PRPF8
SEDCTN3ENSG00000137100.11chr9-346160263461611034614706346147653461788134617968-0.149000.003190.05331excludedHepG2U2AF1
SEDCTN3ENSG00000137100.11chr9-346160263461611034614706346147653461788134617968-0.123000.000000.00016excludedK562AKAP8L
SEDCTN3ENSG00000137100.11chr9-346160263461611034614706346147653461788134617968-0.152000.000050.08635excludedK562IGF2BP1
SEDCTN3ENSG00000137100.11chr9-346160263461611034614706346147653461788134617968-0.259000.000060.00130excludedHepG2U2AF2
SEDCTN3ENSG00000137100.11chr9-346160263461611034614706346147653461788134617968-0.298000.000190.04903excludedK562METAP2
SEDCTN3ENSG00000137100.11chr9-346160263461611034614706346147653461788134618021-0.143000.000000.00000excludedK562AQR
SEDCTN3ENSG00000137100.11chr9-346160263461611034614706346147653461788134617968-0.214000.000000.00000excludedK562PUS1
SEDCTN3ENSG00000137100.11chr9-346160263461611034614706346147653461788134617968-0.165000.000030.03430excludedK562DDX21
SEDCTN3ENSG00000137100.11chr9-346160263461611034614706346147653461788134617968-0.156000.000250.03909excludedK562RBM22
SEDCTN3ENSG00000137100.11chr9-346160263461611034614706346147653461788134617968-0.142000.000000.00005excludedK562UTP18
SEDCTN3ENSG00000137100.11chr9-346160263461611034614706346147653461788134617968-0.125000.000000.00013excludedK562RBM15
SEDCTN3ENSG00000137100.11chr9-346160263461611034614706346147653461788134617968-0.071000.002100.04917excludedK562AGGF1
SEDCTN3ENSG00000137100.11chr9-346160263461611034614706346147653461788134617968-0.577000.000000.00000excludedK562SF3B1
SEDCTN3ENSG00000137100.11chr9-346160263461611034614706346147653461788134617968-0.242000.000000.00000excludedK562HNRNPC
A3SSDCTN3ENSG00000137100.11chr9-3461403834614195346140383461409834614706346147650.111000.000520.02260longerK562U2AF2
A3SSDCTN3ENSG00000137100.11chr9-3461403834614195346140383461409834614706346149390.174000.000000.00000longerK562AQR
A3SSDCTN3ENSG00000137100.11chr9-3461403834614195346140383461409834614706346147650.065000.002720.09065longerHepG2U2AF1
RIDCTN3ENSG00000137100.11chr9-346147063461796834614706346147653461788134617968-0.429000.001170.02035excludedK562SF3B4
RIDCTN3ENSG00000137100.11chr9-346147063461796834614706346147653461788134617968-0.323000.002360.01610excludedK562PUS1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for DCTN3 is not avaliable on ENCORE database.