UBE3B

General Information

Gene Name       : UBE3B
Gene ID             : ENSG00000151148.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: UBE3B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878UBE3BENSG00000151148.138.658.768.71ENCSR000AEF
HepG2UBE3BENSG00000151148.1316.2218.4317.32ENCSR985KAT
K562UBE3BENSG00000151148.1310.7111.5111.11ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for UBE3B is not avaliable on ENCORE database.



Proteins bound to RNA
  • UBE3B RNA is bound by 8 proteins.  







eCLIP assay for UBE3B is not avaliable on ENCORE database.





8 proteins are bound to UBE3B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr12109958936109958999+3'-UTR,CDS,intron-Proximal4.006213.70678K562BUD13
chr12109915582109915627+5'-UTR,intron-Proximal4.058713.32488HepG2DDX3X
chr12109915568109915618+5'-UTR,intron-Proximal3.895794.00320K562AQR
chr12109915627109915712+5'-UTR,intron-Distal,intron-Proximal3.131503.12542HepG2DDX3X
chr12109948092109948198+CDS,intron-Proximal4.744595.07796HepG2SF3B4
chr12109954677109954747+CDS,intron-Proximal5.445567.28294K562AQR
chr12109948094109948181+CDS,intron-Proximal4.001508.55183K562SF3B4
chr12109921455109921517+CDS3.991224.32914K562YBX3
chr12109921691109921787+CDS,intron-Proximal3.345604.34695HepG2BCLAF1
chr12109937437109937598+CDS,intron-Proximal3.867413.34184HepG2GRWD1
chr12109923816109923876+CDS,intron-Proximal4.466164.84481HepG2PPIG
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for UBE3B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for UBE3B is not available on ENCORE database.

  • 59 RBPs can affect the levels of UBE3B.  








The Knockdown/knockout RNA-Seq assay for UBE3B is not available on ENCORE database.





59 RBPs can affect the gene expression of UBE3B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
UBE3BENSG00000151148.9853.914101141.17730-0.418402.772801.73400HepG2AKAP8
UBE3BENSG00000151148.91191.78990857.508200.474803.733602.82530HepG2ASCC1
UBE3BENSG00000151148.91063.07570760.578900.483004.335903.60580HepG2BOP1
UBE3BENSG00000151148.91166.95140814.694800.518304.440203.47150HepG2CIRBP
UBE3BENSG00000151148.91249.90500709.615100.816605.938204.81470HepG2CNOT7
UBE3BENSG00000151148.9939.37360739.554900.344902.468801.82430HepG2DDX21
UBE3BENSG00000151148.91509.78560992.753700.604705.863504.98490HepG2DDX3X
UBE3BENSG00000151148.91062.60710846.787900.327403.315302.58340HepG2DKC1
UBE3BENSG00000151148.91918.889101371.425500.484508.294107.35000HepG2ETF1
UBE3BENSG00000151148.91115.86890699.445500.673802.577701.60000HepG2FTO
UBE3BENSG00000151148.9782.82340622.478600.330602.029501.34740HepG2FUBP3
UBE3BENSG00000151148.91286.65600847.972300.601405.385204.46940HepG2G3BP1
UBE3BENSG00000151148.9931.67650750.529200.311801.968401.37280HepG2HNRNPC
UBE3BENSG00000151148.91099.46410755.379400.541404.759703.95670HepG2HNRNPLL
UBE3BENSG00000151148.9602.49610745.56780-0.307402.543701.96250HepG2HNRNPU
UBE3BENSG00000151148.91145.96460861.932500.410802.977102.28080HepG2IGF2BP2
UBE3BENSG00000151148.9926.492001201.31240-0.374802.090501.37640HepG2LARP4
UBE3BENSG00000151148.91250.09010914.469700.450903.394802.66760HepG2MAGOH
UBE3BENSG00000151148.9699.94920919.57670-0.393702.257501.68380HepG2MATR3
UBE3BENSG00000151148.9667.29490853.30410-0.354702.528901.75390HepG2MSI2
UBE3BENSG00000151148.91184.81210873.809200.439205.876405.04460HepG2PCBP1
UBE3BENSG00000151148.91329.83730901.509400.5607010.717409.64180HepG2PUS1
UBE3BENSG00000151148.91149.99070962.981100.255901.871801.34310HepG2QKI
UBE3BENSG00000151148.9551.19320777.76150-0.496802.080201.46120HepG2RAVER1
UBE3BENSG00000151148.91269.12760989.512800.358903.915103.29260HepG2NELFE
UBE3BENSG00000151148.91332.34230747.682600.833408.192707.03890HepG2SF3B1
UBE3BENSG00000151148.91111.95950925.722600.264402.274201.73120HepG2SF3B4
UBE3BENSG00000151148.91062.71580920.184600.207701.921101.31850HepG2SLBP
UBE3BENSG00000151148.91443.25750966.234700.5788010.484709.69570HepG2SRSF1
UBE3BENSG00000151148.91256.502301077.590300.221502.269801.69640HepG2SUCLG1
UBE3BENSG00000151148.9988.34260711.931800.473204.706403.49360HepG2SUPT6H
UBE3BENSG00000151148.9970.19890668.301600.537703.144002.42780HepG2SUPV3L1
UBE3BENSG00000151148.9617.72080447.895600.463702.380601.44910HepG2TFIP11
UBE3BENSG00000151148.91044.79750724.493500.528106.284205.58590HepG2TIAL1
UBE3BENSG00000151148.9761.17050968.83500-0.348003.552202.88940HepG2UTP3
UBE3BENSG00000151148.91004.61500807.944500.314203.427702.69310HepG2ZC3H8
UBE3BENSG00000151148.91349.648001103.652700.290203.874903.25660HepG2ZNF622
UBE3BENSG00000151148.9945.985001297.09690-0.455406.311905.50700K562AGGF1
UBE3BENSG00000151148.9493.87280633.18290-0.358502.942301.38670K562AKAP1
UBE3BENSG00000151148.91055.517201425.30780-0.433304.052902.81400K562AKAP8
UBE3BENSG00000151148.9769.282501349.68670-0.8110011.8370010.35590K562AKAP8L
UBE3BENSG00000151148.91040.213801416.14370-0.445105.706804.33940K562ATP5C1
UBE3BENSG00000151148.91523.415001291.814900.237802.353701.74530K562DDX47
UBE3BENSG00000151148.91096.524101452.36810-0.405505.164003.91350K562DKC1
UBE3BENSG00000151148.91263.427901029.730900.295002.913402.17900K562EIF2S2
UBE3BENSG00000151148.9836.41880670.250900.319402.070901.35730K562EIF4A3
UBE3BENSG00000151148.92114.823901609.615800.393705.966304.60310K562EIF4G2
UBE3BENSG00000151148.9885.96970697.030500.345903.100802.46560K562FXR1
UBE3BENSG00000151148.9714.59940906.43610-0.343102.700301.64110K562HNRNPA1
UBE3BENSG00000151148.9976.46230698.197000.483804.466003.72610K562HNRNPC
UBE3BENSG00000151148.9831.899601003.75810-0.270902.228801.42750K562HNRNPU
UBE3BENSG00000151148.91131.078901432.35970-0.340702.405001.64420K562KIF1C
UBE3BENSG00000151148.91009.425901371.11680-0.441803.526202.26620K562MAK16
UBE3BENSG00000151148.91074.086601604.60400-0.579107.404505.77420K562MBNL1
UBE3BENSG00000151148.9684.792501124.71080-0.715805.720504.29020K562NAA15
UBE3BENSG00000151148.9553.97930772.33230-0.479403.733202.59820K562PCBP2
UBE3BENSG00000151148.91090.45880839.071000.378003.341002.45590K562POLR2G
UBE3BENSG00000151148.9822.668701338.52870-0.702308.258807.36990K562PUS1
UBE3BENSG00000151148.9765.790901304.18640-0.7681013.5884012.26890K562RBM15
UBE3BENSG00000151148.91075.44770850.988000.337602.287701.31640K562NELFE
UBE3BENSG00000151148.9837.12410586.773000.512503.658702.48790K562RPS3
UBE3BENSG00000151148.9429.84160557.41980-0.375002.638801.80570K562SF3B4
UBE3BENSG00000151148.91393.101801205.757400.208302.166801.32880K562SRPK2
UBE3BENSG00000151148.91505.61520826.773800.8647015.9124014.22050K562SRSF1
UBE3BENSG00000151148.9379.76720519.59740-0.452302.448601.43200K562U2AF1
UBE3BENSG00000151148.9406.12260536.68810-0.402202.819602.00830K562U2AF2
UBE3BENSG00000151148.91511.652001264.488500.257502.753902.03600K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for UBE3B is not available on ENCORE database.





8 RBPs can affect the splicing of UBE3B :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEUBE3BENSG00000151148.9chr12+109946335109946524109945368109945540109947400109947519-0.123000.000060.00203excludedK562SRSF1
SEUBE3BENSG00000151148.9chr12+1099463351099465241099453681099455401099474001099475190.381000.001550.02994includedK562SF3B4
SEUBE3BENSG00000151148.9chr12+109961782109961920109959245109959356109962242109962308-0.496000.000370.01171excludedHepG2HNRNPK
SEUBE3BENSG00000151148.9chr12+1099463351099465241099453681099455401099474001099475190.179000.001040.01267includedK562AQR
SEUBE3BENSG00000151148.9chr12+1099463351099465241099453681099455401099474001099475190.598000.000000.00021includedK562HNRNPA1
SEUBE3BENSG00000151148.9chr12+109946335109946524109945368109945540109947400109947519-0.169000.000000.00015excludedHepG2SRSF1
SEUBE3BENSG00000151148.9chr12+109946335109946524109945368109945540109947400109947519-0.208000.000820.07220excludedHepG2SUPV3L1
SEUBE3BENSG00000151148.9chr12+109946335109946524109945368109945540109947400109947519-0.158000.000740.03784excludedHepG2PCBP1
SEUBE3BENSG00000151148.9chr12+1099661291099662031099641621099642211099676941099678770.303000.002800.04580includedK562U2AF2
SEUBE3BENSG00000151148.9chr12+1099463351099465241099453681099455401099474001099475190.426000.001870.03303includedK562U2AF2
SEUBE3BENSG00000151148.9chr12+109961782109961920109959245109959356109962242109962308-0.301000.000110.00773excludedK562HNRNPK

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for UBE3B is not avaliable on ENCORE database.