TSPO

General Information

Gene Name       : TSPO
Gene ID             : ENSG00000100300.17
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TSPO)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TSPOENSG00000100300.170.080.940.51ENCSR000AEF
HepG2TSPOENSG00000100300.170.700.080.39ENCSR985KAT
K562TSPOENSG00000100300.1728.067.7117.88ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TSPO is not avaliable on ENCORE database.



Proteins bound to RNA
  • TSPO RNA is bound by 4 proteins.  







eCLIP assay for TSPO is not avaliable on ENCORE database.





4 proteins are bound to TSPO RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr224355718543557245+3'-UTR,CDS,intron-Proximal4.964545.17615K562AQR
chr224355521443555230+3'-UTR,intron-Distal,intron-Proximal4.131674.08283K562DDX3X
chr224355906343559089+3'-UTR,CDS3.035655.59049K562YBX3
chr224354755143547611+5'-UTR,intron-Proximal4.745637.22925K562DDX3X
chr224354913143549172+intron-Distal5.082345.39854K562PTBP1
chr224354917243549216+intron-Distal4.254326.85458K562PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TSPO is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TSPO is not available on ENCORE database.

  • 50 RBPs can affect the levels of TSPO.  








The Knockdown/knockout RNA-Seq assay for TSPO is not available on ENCORE database.





50 RBPs can affect the gene expression of TSPO :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TSPOENSG00000100300.1325.737505.373702.259801.808901.36880HepG2AKAP1
TSPOENSG00000100300.1342.146504.425203.251505.938205.06150HepG2DDX6
TSPOENSG00000100300.130.000008.82890-99999.999992.586002.08500HepG2SSB
TSPOENSG00000100300.1316.809201.527303.460103.539002.91870HepG2TRIM56
TSPOENSG00000100300.13666.97080436.731400.610807.198406.34630K562AGGF1
TSPOENSG00000100300.13857.17260479.926400.836702.512601.58460K562AKAP8
TSPOENSG00000100300.13806.03220454.444800.826603.626702.87570K562AKAP8L
TSPOENSG00000100300.13291.47110507.20300-0.799205.974905.16930K562AQR
TSPOENSG00000100300.13633.77570476.833500.410403.556002.50840K562ATP5C1
TSPOENSG00000100300.13317.51800144.817201.132509.479807.68560K562BCLAF1
TSPOENSG00000100300.13269.35230109.865501.293702.644201.61310K562CSTF2
TSPOENSG00000100300.13357.02480633.30940-0.826903.180902.13710K562CELF1
TSPOENSG00000100300.13187.13580126.973900.559502.574701.30140K562DDX27
TSPOENSG00000100300.13332.25990235.768800.494803.045102.29660K562EIF2S2
TSPOENSG00000100300.13211.49130357.31160-0.756602.436801.66550K562EIF4A3
TSPOENSG00000100300.13193.80410106.552600.862904.476203.37850K562FIP1L1
TSPOENSG00000100300.1341.23070150.10830-1.864207.218405.25720K562FKBP4
TSPOENSG00000100300.13171.47860371.58890-1.1157011.8750010.71150K562FXR1
TSPOENSG00000100300.135.5613047.26620-3.087307.342506.07400K562G3BP2
TSPOENSG00000100300.13458.58200314.197800.545403.606102.74790K562GRSF1
TSPOENSG00000100300.1370.61430172.61200-1.289507.036206.12640K562HNRNPC
TSPOENSG00000100300.13377.79200114.896301.717202.328001.40980K562IGF2BP2
TSPOENSG00000100300.13194.14830116.842400.732502.744901.55930K562IGF2BP3
TSPOENSG00000100300.1375.91950154.47120-1.024803.280101.71090K562ILF2
TSPOENSG00000100300.1391.05130167.36440-0.878203.476401.87700K562LARP7
TSPOENSG00000100300.13208.15160120.695200.786204.447503.37680K562MAGOH
TSPOENSG00000100300.13662.13000461.657100.520204.339502.90390K562MAK16
TSPOENSG00000100300.13235.07450120.441800.964704.164603.01390K562MATR3
TSPOENSG00000100300.13192.37660356.79810-0.891207.448405.46470K562NCBP2
TSPOENSG00000100300.13255.98140112.715101.183303.092201.70330K562NONO
TSPOENSG00000100300.13576.04890263.651501.127506.601204.87380K562PABPN1
TSPOENSG00000100300.1394.40870195.72910-1.051905.207404.06370K562PCBP3
TSPOENSG00000100300.13303.20420120.985701.3254010.718508.79960K562PPIG
TSPOENSG00000100300.13523.43850313.671500.738703.020901.47890K562PPP1R8
TSPOENSG00000100300.13346.06910597.69100-0.788302.567401.54150K562PUM1
TSPOENSG00000100300.13690.14440439.117900.652207.532006.58350K562RBM15
TSPOENSG00000100300.13168.09330112.414500.580302.267501.51130K562RBM22
TSPOENSG00000100300.1377.11710150.99890-0.969403.045601.38030K562RPS3A
TSPOENSG00000100300.1324.1546057.16910-1.242902.442401.53330K562SF3B1
TSPOENSG00000100300.13231.15710114.967201.007602.624601.93360K562SRSF1
TSPOENSG00000100300.13185.91370101.379300.874802.463001.47790K562SRSF4
TSPOENSG00000100300.13282.27810108.593501.3781012.045909.70760K562SRSF5
TSPOENSG00000100300.1382.06210150.58750-0.875803.911702.93510K562SYNCRIP
TSPOENSG00000100300.1312.4551046.40200-1.897503.804101.97860K562TAF15
TSPOENSG00000100300.13319.54050116.340701.4575014.2737012.42240K562TARDBP
TSPOENSG00000100300.13326.42610112.227301.5402016.6790014.54350K562TIA1
TSPOENSG00000100300.13284.39940110.160601.3682011.619308.96710K562TRA2A
TSPOENSG00000100300.1316.3766045.87880-1.486202.850201.73930K562U2AF1
TSPOENSG00000100300.1310.1001047.36240-2.229405.539204.40620K562U2AF2
TSPOENSG00000100300.13147.82820314.18900-1.087702.548001.73350K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TSPO is not available on ENCORE database.





2 RBPs can affect the splicing of TSPO :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETSPOENSG00000100300.13chr22+4355521543555342435475194354761043557057435571960.231000.002130.04978includedK562AGGF1
SETSPOENSG00000100300.13chr22+435552154355542643547519435476104355705743557196-0.365000.000370.02152excludedK562HNRNPK

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TSPO is not avaliable on ENCORE database.