TGS1

General Information

Gene Name       : TGS1
Gene ID             : ENSG00000137574.10
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: TGS1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TGS1ENSG00000137574.1024.6522.1123.38ENCSR000AEF
HepG2TGS1ENSG00000137574.109.8116.0012.91ENCSR985KAT
K562TGS1ENSG00000137574.1017.4417.8617.65ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TGS1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TGS1 RNA is bound by 11 proteins.  







eCLIP assay for TGS1 is not avaliable on ENCORE database.





11 proteins are bound to TGS1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr85671502356715063+3'-UTR,CDS3.548043.61259K562ZNF622
chr85673793756737996+3'-UTR4.652529.17735K562PUM2
chr85671501756715098+3'-UTR,CDS4.6937911.82742K562UCHL5
chr85671501356715058+3'-UTR,CDS,intron-Proximal3.034234.38519K562BUD13
chr85669919956699291+5'-UTR,CDS4.620924.48994K562RBM15
chr85669920756699297+5'-UTR,CDS3.284956.72164K562UCHL5
chr85669957556699620+5'-UTR,CDS,intron-Proximal3.850855.03335K562UCHL5
chr85671174056711778+5'-UTR,CDS4.018593.00996K562BUD13
chr85670532056705343+5'-UTR,CDS4.542514.78571K562UCHL5
chr85670530156705331+5'-UTR,CDS3.236224.62864K562ZNF622
chr85671173756711777+5'-UTR,CDS3.847075.85226K562UCHL5
chr85670281356702850+5'-UTR,CDS3.821405.30520K562UCHL5
chr85668606456686151+5'-UTR3.024993.33365K562DDX3X
chr85668602456686164+5'-UTR3.987143.45994HepG2NCBP2
chr85669907856699179+5'-UTR,CDS3.260805.46976K562UCHL5
chr85669532656695369+CDS,intron-Distal3.286193.73997K562ZNF622
chr85668619256686281+CDS,intron-Proximal4.076123.53067K562SRSF1
chr85668628056686404+intron-Distal,intron-Proximal4.733066.93191K562KHSRP
chr85673039856730517+intron-Distal3.002996.35060HepG2HNRNPL
chr85673040356730528+intron-Distal4.144838.24016K562HNRNPL
chr85670286356702973+intron-Distal,intron-Proximal3.017773.31830K562KHSRP
chr85670544256705545+intron-Distal,intron-Proximal4.057189.06934K562KHSRP
chr85670286156702919+intron-Proximal4.153078.27931K562AQR
chr85670535056705442+intron-Proximal3.143943.48890K562KHSRP
chr85670285856702861+intron-Proximal5.199635.65342K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TGS1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TGS1 is not available on ENCORE database.

  • 67 RBPs can affect the levels of TGS1.  








The Knockdown/knockout RNA-Seq assay for TGS1 is not available on ENCORE database.





67 RBPs can affect the gene expression of TGS1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TGS1ENSG00000137574.6624.50830410.725500.604403.758203.15150HepG2AKAP1
TGS1ENSG00000137574.6409.10180643.86610-0.654307.753606.69710HepG2AUH
TGS1ENSG00000137574.6180.16360362.04590-1.006907.607906.20580HepG2BCLAF1
TGS1ENSG00000137574.6318.63750601.51650-0.916709.694508.66130HepG2BOP1
TGS1ENSG00000137574.6193.63860552.21590-1.5119019.6078017.98280HepG2CPSF6
TGS1ENSG00000137574.6404.29670540.54900-0.419003.661202.82820HepG2DAZAP1
TGS1ENSG00000137574.6225.47730327.85430-0.540103.433802.65590HepG2DNAJC21
TGS1ENSG00000137574.6221.42700324.97600-0.553504.098903.33610HepG2DNAJC2
TGS1ENSG00000137574.6200.37310324.94540-0.697503.409002.75490HepG2EIF2S1
TGS1ENSG00000137574.6245.01170376.14080-0.618402.459501.40440HepG2FUS
TGS1ENSG00000137574.6308.84870208.832900.564502.777601.87730HepG2GEMIN5
TGS1ENSG00000137574.6382.68010625.95480-0.709905.352304.48080HepG2GPKOW
TGS1ENSG00000137574.6369.86220544.12950-0.557005.255004.30600HepG2HNRNPF
TGS1ENSG00000137574.6361.44420492.39240-0.446003.763602.98470HepG2HNRNPL
TGS1ENSG00000137574.6309.70600597.36250-0.947709.135908.06540HepG2HNRNPLL
TGS1ENSG00000137574.6250.05950365.74220-0.548604.178103.44560HepG2HNRNPU
TGS1ENSG00000137574.6359.86010535.81500-0.574304.720403.79750HepG2IGF2BP1
TGS1ENSG00000137574.6222.73910373.59260-0.746107.517806.37310HepG2ILF2
TGS1ENSG00000137574.6523.31910362.343100.530203.248002.53800HepG2MAGOH
TGS1ENSG00000137574.6642.50270364.396100.818102.884002.24100HepG2MATR3
TGS1ENSG00000137574.6387.22870249.404800.634602.673601.80450HepG2PABPC1
TGS1ENSG00000137574.6593.11050374.379900.663703.684902.28580HepG2PRPF6
TGS1ENSG00000137574.6361.82770511.67270-0.499903.364802.71640HepG2PUF60
TGS1ENSG00000137574.6326.67780586.11980-0.843308.241707.16210HepG2RPLP0
TGS1ENSG00000137574.6825.94360450.225100.875307.173706.05280HepG2SF3A3
TGS1ENSG00000137574.6561.50180697.85600-0.313602.377201.90130HepG2SRFBP1
TGS1ENSG00000137574.6262.56060390.19460-0.571503.041301.34160HepG2SRP68
TGS1ENSG00000137574.6836.83210390.276701.1003020.0416019.01500HepG2SRSF1
TGS1ENSG00000137574.6356.83810534.57980-0.583105.730504.78700HepG2SRSF7
TGS1ENSG00000137574.6696.82070574.556400.278202.225101.65630HepG2SUCLG1
TGS1ENSG00000137574.6287.43250407.82820-0.504702.424201.78610HepG2SUPV3L1
TGS1ENSG00000137574.6347.47730582.30940-0.744906.247605.21820HepG2TARDBP
TGS1ENSG00000137574.6249.65930358.56520-0.522303.949503.29980HepG2TRIM56
TGS1ENSG00000137574.6578.97330375.498400.624605.064704.22870HepG2U2AF1
TGS1ENSG00000137574.6159.55850240.90790-0.594402.791002.02750HepG2UCHL5
TGS1ENSG00000137574.6618.32610385.490000.681607.933607.00300HepG2UTP3
TGS1ENSG00000137574.6997.590601363.44340-0.450706.428205.61520K562AGGF1
TGS1ENSG00000137574.6985.722201418.72060-0.525305.647104.69520K562AKAP8L
TGS1ENSG00000137574.62193.847601613.256400.443404.475803.76250K562AQR
TGS1ENSG00000137574.6812.366601016.04290-0.322802.886601.53790K562BCCIP
TGS1ENSG00000137574.6675.13730981.84150-0.540307.515305.90800K562BCLAF1
TGS1ENSG00000137574.6659.948101028.31360-0.639904.167303.08940K562BOP1
TGS1ENSG00000137574.61304.797401629.40300-0.320502.978401.74680K562CCDC124
TGS1ENSG00000137574.6790.617201093.45430-0.467802.737101.95910K562CPSF6
TGS1ENSG00000137574.6584.11710744.87310-0.350702.466101.47550K562CSTF2
TGS1ENSG00000137574.6468.70260688.97940-0.555805.303003.79710K562DDX3X
TGS1ENSG00000137574.61782.943701481.836900.266803.186802.49480K562DDX47
TGS1ENSG00000137574.61017.919101301.62260-0.354702.364801.69150K562EIF2S2
TGS1ENSG00000137574.6430.21970728.96710-0.760804.198602.07830K562FAM120A
TGS1ENSG00000137574.6905.897401306.56430-0.528403.533502.56520K562FIP1L1
TGS1ENSG00000137574.6857.604601112.44400-0.375302.062801.32060K562FMR1
TGS1ENSG00000137574.6513.43510795.65750-0.632007.277504.97990K562FUS
TGS1ENSG00000137574.61093.64170748.525100.546907.335306.41350K562FXR1
TGS1ENSG00000137574.61289.91920777.844900.729606.357905.18900K562G3BP2
TGS1ENSG00000137574.6746.003201044.02920-0.484902.776101.98070K562GPKOW
TGS1ENSG00000137574.6996.980801734.73980-0.799106.914005.71170K562GRSF1
TGS1ENSG00000137574.6525.51200760.68990-0.533604.622703.87000K562HNRNPC
TGS1ENSG00000137574.6898.539601082.74210-0.269002.201601.40600K562HNRNPU
TGS1ENSG00000137574.6555.161101000.84570-0.850209.138506.04470K562KHSRP
TGS1ENSG00000137574.61233.545101505.63150-0.287602.120601.40930K562KIF1C
TGS1ENSG00000137574.6556.90880891.34100-0.678504.678603.42630K562KRR1
TGS1ENSG00000137574.6673.136501083.61770-0.6869012.4258010.85410K562MTPAP
TGS1ENSG00000137574.6996.660901204.00040-0.272703.343102.52940K562NSUN2
TGS1ENSG00000137574.6774.313901260.28030-0.702803.171902.09210K562PABPN1
TGS1ENSG00000137574.61027.385501483.08070-0.529603.855502.86270K562PPIG
TGS1ENSG00000137574.61054.95690797.129100.404203.062602.27310K562PRPF8
TGS1ENSG00000137574.62684.987702236.767000.263402.850601.76660K562PUM1
TGS1ENSG00000137574.6830.590801407.01090-0.760408.862407.93860K562PUS1
TGS1ENSG00000137574.6971.468801370.89580-0.496906.529705.64440K562RBM15
TGS1ENSG00000137574.61245.35610990.508200.330202.812902.10110K562SRSF1
TGS1ENSG00000137574.61084.04040753.770700.524106.092804.86570K562SYNCRIP
TGS1ENSG00000137574.6806.709201002.55690-0.313601.976201.37070K562TARDBP
TGS1ENSG00000137574.6530.04160696.86470-0.394802.721001.78380K562TRIM56
TGS1ENSG00000137574.61008.07950754.828700.417302.786801.69030K562U2AF1
TGS1ENSG00000137574.61087.740501276.62690-0.231002.189001.54460K562UPF1
TGS1ENSG00000137574.6942.266901222.32130-0.375402.584801.42830K562UTP3
TGS1ENSG00000137574.6834.688501092.36980-0.388203.450802.47610K562WDR3
TGS1ENSG00000137574.61507.820601817.50050-0.269502.090301.35090K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TGS1 is not available on ENCORE database.





9 RBPs can affect the splicing of TGS1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETGS1ENSG00000137574.6chr8+567052565670534356702655567028585670853656708711-0.075000.005110.07710excludedK562SRSF1
SETGS1ENSG00000137574.6chr8+566953065669537156685700566862785669827756698450-0.269000.000000.00015excludedK562AKAP8L
SETGS1ENSG00000137574.6chr8+566987965669961956698277566984505670274056702858-0.064000.000690.02351excludedK562AKAP8L
SETGS1ENSG00000137574.6chr8+567052565670534356702687567028585670853656708711-0.139000.000000.00002excludedK562AQR
SETGS1ENSG00000137574.6chr8+566953065669537156685700566862785669827756698450-0.267000.000000.00000excludedK562AQR
SETGS1ENSG00000137574.6chr8+5671073056710973567085365670871156711472567115570.185000.000110.00268includedK562PUS1
SETGS1ENSG00000137574.6chr8+566953065669537156685700566862785669827756698450-0.340000.000000.00001excludedK562PUS1
SETGS1ENSG00000137574.6chr8+566953065669537156685700566862785669827756698450-0.146000.000280.02716excludedK562HNRNPUL1
SETGS1ENSG00000137574.6chr8+566953065669537156685700566862785669827756698450-0.217000.000090.00410excludedK562RBM15
SETGS1ENSG00000137574.6chr8+566953065669537156685700566862785669827756698450-0.308000.000000.00002excludedK562AGGF1
SETGS1ENSG00000137574.6chr8+567085365670871156705256567053435671147256711557-0.113000.003540.07179excludedK562AGGF1
SETGS1ENSG00000137574.6chr8+566953065669537156685700566862785669827756698450-0.177000.000050.01685excludedK562NPM1
A3SSTGS1ENSG00000137574.6chr8+5671498356715165567150155671516556711472567117790.083000.000000.00001longerK562AQR
A3SSTGS1ENSG00000137574.6chr8+5670268456702858567027405670285856698796566996190.059000.000000.00002longerK562AQR
MXETGS1ENSG00000137574.6chr8+5670525656705343567107305671097356702655567028585671147256711557-0.123000.000070.004352includedK562AGGF1
MXETGS1ENSG00000137574.6chr8+5670525656705343567085365670871156702655567028585671147256711557-0.176000.000200.005292includedK562SRSF1
MXETGS1ENSG00000137574.6chr8+56708536567087115671147256711779567027405670285856715015567151650.132000.000010.000141includedK562AQR
MXETGS1ENSG00000137574.6chr8+56705160567053435670850656708711567026555670285856711472567115570.057000.009920.062911includedK562AQR
MXETGS1ENSG00000137574.6chr8+5670853656708711567114725671160556705160567053435671501556715165-0.061000.016010.092242includedK562AQR
MXETGS1ENSG00000137574.6chr8+5670853656708711567108065671097356705256567053435671147256711557-0.051000.002910.091472includedK562HNRNPU

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TGS1 is not avaliable on ENCORE database.