TBC1D22B

General Information

Gene Name       : TBC1D22B
Gene ID             : ENSG00000065491.8
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TBC1D22B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TBC1D22BENSG00000065491.811.4812.7012.09ENCSR000AEF
HepG2TBC1D22BENSG00000065491.811.5914.2112.90ENCSR985KAT
K562TBC1D22BENSG00000065491.815.6916.3116.00ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TBC1D22B is not avaliable on ENCORE database.



Proteins bound to RNA
  • TBC1D22B RNA is bound by 21 proteins.  







eCLIP assay for TBC1D22B is not avaliable on ENCORE database.





21 proteins are bound to TBC1D22B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr63729908737299137+3'-UTR4.350685.03175K562IGF2BP1
chr63729904537299084+3'-UTR4.428795.35091K562PUM2
chr63729902937299126+3'-UTR4.599846.39896K562IGF2BP2
chr63730037737300432+3'-UTR4.450864.78334K562IGF2BP2
chr63729958137299654+3'-UTR3.060383.68882K562FAM120A
chr63729955537299632+3'-UTR3.170553.44195K562TARDBP
chr63729907837299196+3'-UTR3.955983.57526HepG2IGF2BP1
chr63729912637299182+3'-UTR4.334464.29122K562IGF2BP2
chr63729975837299840+3'-UTR6.3344021.42262K562PUM2
chr63722555337225620+5'-UTR3.111103.52645HepG2NCBP2
chr63725064737250741+CDS,intron-Proximal3.042725.24578K562BUD13
chr63728066937280737+CDS,intron-Proximal3.556306.90700K562BUD13
chr63725060437250699+CDS,intron-Proximal3.804366.71722K562SF3B4
chr63728488637284958+CDS,intron-Proximal3.004954.94039K562YBX3
chr63728064537280704+CDS,intron-Proximal4.504248.28159K562SF3B4
chr63724738537247437+CDS,intron-Proximal4.549855.47926K562AQR
chr63728161837281707+CDS,intron-Proximal5.6869223.67538HepG2PRPF8
chr63728496237285020+CDS,intron-Proximal4.580266.04280HepG2PRPF8
chr63724713637247224+CDS3.141443.78791K562RBM15
chr63725912437259178+CDS,intron-Proximal3.334663.18246K562PRPF8
chr63725206937252163+CDS,intron-Proximal3.670017.67169K562SF3B4
chr63725223937252247+CDS,intron-Proximal5.3957914.28850K562AQR
chr63728494937285021+CDS,intron-Proximal3.442176.73756K562PRPF8
chr63728460137284654+CDS,intron-Proximal4.680265.68502HepG2PRPF8
chr63725064837250710+CDS,intron-Proximal3.628234.86518HepG2BUD13
chr63725216937252250+CDS,intron-Proximal3.027139.60227K562ZNF622
chr63725001937250071+CDS3.496854.40383K562UCHL5
chr63728483537284915+CDS,intron-Proximal4.437687.39218K562SF3B4
chr63728173037281826+intron-Distal,intron-Proximal3.626813.84119K562EFTUD2
chr63728846237288520+intron-Distal4.523023.18269HepG2XPO5
chr63726782237267942+intron-Distal4.352085.51743K562QKI
chr63722593137226021+intron-Distal3.893933.25631HepG2PRPF4
chr63727388237273972+intron-Distal3.698205.99692K562HNRNPM
chr63728511637285223+intron-Distal3.225528.23020K562EFTUD2
chr63728238737282473+intron-Distal4.955776.38584HepG2QKI
chr63728171537281776+intron-Distal,intron-Proximal3.085914.07440K562PRPF8
chr63727098737271085+intron-Distal3.026353.66723K562MATR3
chr63727688837276958+intron-Distal4.245034.30850HepG2QKI
chr63726872937268783+intron-Distal5.078547.79030HepG2PCBP2
chr63728510337285174+intron-Distal4.008646.08301HepG2EFTUD2
chr63725485637254922+intron-Proximal3.545393.47285K562PRPF8
chr63723742637237487+intron-Proximal4.734824.86944K562AQR
chr63725224737252284+intron-Proximal4.5157613.09382K562AQR
chr63725014037250188+intron-Proximal4.623638.01338K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TBC1D22B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TBC1D22B is not available on ENCORE database.

  • 56 RBPs can affect the levels of TBC1D22B.  








The Knockdown/knockout RNA-Seq assay for TBC1D22B is not available on ENCORE database.





56 RBPs can affect the gene expression of TBC1D22B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TBC1D22BENSG00000065491.8721.116001004.74480-0.478503.064602.50830HepG2AKAP1
TBC1D22BENSG00000065491.8414.70570547.29140-0.400202.166601.34080HepG2BCCIP
TBC1D22BENSG00000065491.8361.94280475.49980-0.393702.223001.41730HepG2BCLAF1
TBC1D22BENSG00000065491.8443.84530578.33470-0.381802.186701.64940HepG2BOP1
TBC1D22BENSG00000065491.81023.22410789.811300.373402.402201.67640HepG2CIRBP
TBC1D22BENSG00000065491.8535.55190665.05350-0.312402.682302.02480HepG2CKAP4
TBC1D22BENSG00000065491.8782.48370636.468300.297902.374301.73970HepG2DKC1
TBC1D22BENSG00000065491.8493.83870794.74090-0.686405.927905.07660HepG2EIF2S1
TBC1D22BENSG00000065491.8347.45460621.78440-0.839609.573407.57860HepG2EIF2S2
TBC1D22BENSG00000065491.81005.14720843.261200.253302.117901.36970HepG2EIF4G1
TBC1D22BENSG00000065491.8923.958001092.04760-0.241102.215201.66720HepG2ETF1
TBC1D22BENSG00000065491.8428.48750562.74680-0.393202.388901.65720HepG2FUBP3
TBC1D22BENSG00000065491.8649.88860872.88560-0.425602.877601.96500HepG2G3BP2
TBC1D22BENSG00000065491.8764.24520601.913800.344401.834501.30600HepG2GPKOW
TBC1D22BENSG00000065491.81005.70060741.649200.439304.061003.20910HepG2HNRNPF
TBC1D22BENSG00000065491.8510.96510832.70560-0.704606.889305.82570HepG2HNRNPK
TBC1D22BENSG00000065491.8602.11670778.63410-0.370903.999103.20060HepG2HNRNPL
TBC1D22BENSG00000065491.8934.22800730.299500.355202.451501.76800HepG2IGF2BP1
TBC1D22BENSG00000065491.81125.76960835.556800.430003.164302.44800HepG2IGF2BP2
TBC1D22BENSG00000065491.8430.14120573.10490-0.414002.585301.41570HepG2LIN28B
TBC1D22BENSG00000065491.8666.70430886.62260-0.411302.608801.97120HepG2MAGOH
TBC1D22BENSG00000065491.8545.48290809.08710-0.568805.433404.63330HepG2PUF60
TBC1D22BENSG00000065491.8709.01260858.25160-0.275601.902801.34090HepG2PUM2
TBC1D22BENSG00000065491.8901.67640600.848800.585502.841802.12850HepG2RAVER1
TBC1D22BENSG00000065491.81071.59550856.406400.323302.731901.87900HepG2RBM15
TBC1D22BENSG00000065491.8577.18480779.14610-0.432903.440302.69440HepG2RBM25
TBC1D22BENSG00000065491.8493.97230658.23620-0.414202.653901.68220HepG2RBM27
TBC1D22BENSG00000065491.8699.23130882.19360-0.335302.862702.31390HepG2NELFE
TBC1D22BENSG00000065491.81166.72730799.136600.545904.794703.92810HepG2RPLP0
TBC1D22BENSG00000065491.81195.46230802.952200.574103.546502.77930HepG2SF3A3
TBC1D22BENSG00000065491.8892.78000568.576600.650906.584305.53410HepG2SF3B1
TBC1D22BENSG00000065491.8647.07840775.77360-0.261702.179901.54470HepG2SLBP
TBC1D22BENSG00000065491.8400.97750632.63400-0.657803.523102.63660HepG2SNRNP70
TBC1D22BENSG00000065491.82012.413301030.887600.9649033.7395032.49700HepG2SRFBP1
TBC1D22BENSG00000065491.8947.98030611.733800.631904.596403.27690HepG2SRSF3
TBC1D22BENSG00000065491.81044.15070728.691700.518805.207804.30050HepG2SRSF7
TBC1D22BENSG00000065491.8821.31620700.826200.228801.817301.35260HepG2SRSF9
TBC1D22BENSG00000065491.8624.56340908.51650-0.540707.824206.86540HepG2SUCLG1
TBC1D22BENSG00000065491.8730.48040535.655800.447402.143101.53790HepG2SUPV3L1
TBC1D22BENSG00000065491.8533.64690774.31320-0.537005.785105.02550HepG2TAF15
TBC1D22BENSG00000065491.8413.99290584.33470-0.497204.904104.19690HepG2TRIM56
TBC1D22BENSG00000065491.8566.06890790.43200-0.481704.168103.06980HepG2TUFM
TBC1D22BENSG00000065491.8499.34780708.03260-0.503803.570302.86080HepG2U2AF1
TBC1D22BENSG00000065491.8539.79270712.09350-0.399704.007103.19060HepG2UPF1
TBC1D22BENSG00000065491.8876.74850687.501900.350703.534202.87320HepG2UTP3
TBC1D22BENSG00000065491.8995.82250753.516200.402202.841601.95720K562BOP1
TBC1D22BENSG00000065491.82218.95150931.235801.2526012.5342010.30240K562CNOT7
TBC1D22BENSG00000065491.81036.44410801.224500.371302.505701.75770K562CPSF6
TBC1D22BENSG00000065491.8610.41300896.56880-0.554607.023405.95380K562EIF2S2
TBC1D22BENSG00000065491.8686.54300844.56640-0.298902.341801.77700K562FXR1
TBC1D22BENSG00000065491.81103.34170764.988700.528305.219404.13540K562GPKOW
TBC1D22BENSG00000065491.8751.282101016.19860-0.435803.059601.75750K562HNRNPK
TBC1D22BENSG00000065491.8848.04140655.005700.372502.161401.34330K562HNRNPM
TBC1D22BENSG00000065491.8859.607901111.14080-0.370303.813902.76300K562HNRNPU
TBC1D22BENSG00000065491.8758.450601069.27830-0.495505.180204.02120K562MAGOH
TBC1D22BENSG00000065491.81340.652401158.410100.210702.383201.68630K562NSUN2
TBC1D22BENSG00000065491.81286.638301693.66970-0.396503.184702.31110K562PUF60
TBC1D22BENSG00000065491.8798.75870996.20970-0.318702.182801.44060K562RBM22
TBC1D22BENSG00000065491.8655.397701048.33610-0.677707.171605.33390K562NELFE
TBC1D22BENSG00000065491.81519.66550953.503300.672302.560201.32850K562SFPQ
TBC1D22BENSG00000065491.81572.35230898.889900.806603.491102.05450K562SNRNP200
TBC1D22BENSG00000065491.81318.821001018.417700.372803.461802.67680K562SRSF1
TBC1D22BENSG00000065491.81168.71920911.275400.358903.960302.53920K562SRSF7
TBC1D22BENSG00000065491.8434.33500774.00690-0.833507.391605.45020K562U2AF1
TBC1D22BENSG00000065491.8436.63280799.51350-0.8727012.8877011.13990K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TBC1D22B is not available on ENCORE database.





4 RBPs can affect the splicing of TBC1D22B :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETBC1D22BENSG00000065491.8chr6+372590183725913337254782372548483728065537280800-0.389000.002740.05137excludedK562U2AF1
SETBC1D22BENSG00000065491.8chr6+372590183725913337254782372548483728065537280800-0.548000.001000.02005excludedK562U2AF2
A3SSTBC1D22BENSG00000065491.8chr6+3725209937252240372521113725224037250657372507280.066000.012100.06221longerK562AQR
A5SSTBC1D22BENSG00000065491.8chr6+3725065737250789372506573725072837252111372522400.077000.005410.07741longerK562AQR
A5SSTBC1D22BENSG00000065491.8chr6+3725209637252288372520963725224037254782372548480.064000.000040.00110longerK562AQR
MXETBC1D22BENSG00000065491.8chr6+3724707937247387372499603725014037237369372374263725065737250728-0.267000.000060.000742includedK562AQR
MXETBC1D22BENSG00000065491.8chr6+37254782372548483725901837259133372521113725224037280693372808000.118000.003680.052701includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TBC1D22B is not avaliable on ENCORE database.