PSMG4

General Information

Gene Name       : PSMG4
Gene ID             : ENSG00000180822.11
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: PSMG4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PSMG4ENSG00000180822.115.197.766.47ENCSR000AEF
HepG2PSMG4ENSG00000180822.1143.4515.2529.35ENCSR985KAT
K562PSMG4ENSG00000180822.1135.5019.5227.51ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PSMG4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PSMG4 RNA is bound by 18 proteins.  







eCLIP assay for PSMG4 is not avaliable on ENCORE database.





18 proteins are bound to PSMG4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr632651943265276+3'-UTR,intron-Distal3.529843.11181HepG2CSTF2
chr632679013268022+3'-UTR,CDS,intron-Distal4.8906856.18792K562PUM2
chr632680193268121+3'-UTR,intron-Distal3.454624.98044HepG2CSTF2
chr632704013270462+3'-UTR,intron-Distal4.242474.51328K562SAFB2
chr632641773264240+3'-UTR,intron-Distal3.264835.42704K562TIA1
chr632652153265264+3'-UTR,intron-Distal3.194373.69530HepG2CSTF2T
chr632680143268066+3'-UTR,intron-Distal4.829234.24447K562FMR1
chr632678253267976+3'-UTR,CDS,intron-Distal4.522275.05331K562GRWD1
chr632681603268241+3'-UTR,intron-Distal4.037843.14687K562CSTF2T
chr632591973259320+5'-UTR,CDS,intron-Distal3.068276.56867HepG2NCBP2
chr632592183259296+5'-UTR,CDS,intron-Distal4.507675.98323K562DROSHA
chr632592063259356+5'-UTR,CDS,intron-Distal4.6002321.68674K562DDX3X
chr632592553259317+5'-UTR,CDS,intron-Distal3.457854.50608K562DDX52
chr632592383259304+5'-UTR,CDS,intron-Distal4.270764.05620HepG2MATR3
chr632592353259352+5'-UTR,CDS,intron-Distal4.2706720.52959K562NONO
chr632592303259325+5'-UTR,CDS,intron-Distal3.071866.48063K562CSTF2T
chr632592253259341+5'-UTR,CDS,intron-Distal3.6475721.31545K562GEMIN5
chr632592143259308+5'-UTR,CDS,intron-Distal3.6891222.63399HepG2DDX3X
chr632593563259432+CDS,intron-Distal,intron-Proximal3.291247.23254K562DDX3X
chr632593453259465+CDS,intron-Distal,intron-Proximal3.9106512.11025K562GEMIN5
chr632594243259494+CDS,intron-Distal,intron-Proximal3.306423.37274K562AKAP8L
chr632599293260017+intron-Distal3.439263.71597K562MATR3
chr632597863259813+intron-Distal3.832823.45860K562TIA1
chr632594583259522+intron-Distal,intron-Proximal5.325589.05671K562NONO
chr632600793260136+intron-Distal3.530804.63569HepG2RBFOX2
chr632596933259750+intron-Distal5.3880011.51099K562NONO
chr632612873261325+intron-Distal3.009453.36616K562NONO
chr632637303263826+intron-Distal,intron-Proximal3.683657.68379K562NONO
chr632597143259753+intron-Distal3.934663.10243K562SLTM
chr632682933268349+intron-Distal4.037843.59342K562CSTF2T
chr632714743271536+intron-Distal3.126713.72819K562SLTM
chr632614663261597+intron-Distal3.576697.02273K562MATR3
chr632723363272358+intron-Distal4.240144.09073K562SLTM
chr632687013268758+intron-Distal3.878483.06015K562MATR3
chr632724443272505+intron-Distal3.240144.91491K562SLTM
chr632599353260002+intron-Distal4.693544.30178K562PTBP1
chr632731873273278+intron-Distal3.786643.93850HepG2CSTF2
chr632722403272264+intron-Distal3.227143.12654K562SLTM
chr632736683273763+intron-Distal3.382564.37279HepG2CSTF2T
chr632595973259677+intron-Distal3.534377.47864K562NONO
chr632682883268334+intron-Distal3.428974.23312HepG2CSTF2
chr632730843273187+intron-Distal3.512706.17912HepG2CSTF2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PSMG4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PSMG4 is not available on ENCORE database.

  • 46 RBPs can affect the levels of PSMG4.  








The Knockdown/knockout RNA-Seq assay for PSMG4 is not available on ENCORE database.





46 RBPs can affect the gene expression of PSMG4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PSMG4ENSG00000180822.7375.54300532.90800-0.504903.321302.58020HepG2AUH
PSMG4ENSG00000180822.7255.86210337.97020-0.401502.444901.81190HepG2CKAP4
PSMG4ENSG00000180822.7547.89800424.782700.367102.810602.16330HepG2CELF1
PSMG4ENSG00000180822.7426.36540611.90580-0.521205.254804.47380HepG2ETF1
PSMG4ENSG00000180822.7449.99320278.002300.694704.788503.89040HepG2HNRNPK
PSMG4ENSG00000180822.7451.88960248.328500.863605.391304.59010HepG2PCBP1
PSMG4ENSG00000180822.7214.10820432.30520-1.013709.567108.54980HepG2PUF60
PSMG4ENSG00000180822.7624.98960458.929500.445504.902404.15870HepG2PUM1
PSMG4ENSG00000180822.7322.15190458.58280-0.509403.368702.63030HepG2PUM2
PSMG4ENSG00000180822.7318.16920511.42830-0.684706.554505.83820HepG2RBM22
PSMG4ENSG00000180822.7426.04280288.014200.564803.333202.23820HepG2RBM27
PSMG4ENSG00000180822.7220.90880338.22260-0.614503.058902.34980HepG2SF3A3
PSMG4ENSG00000180822.7468.31720577.61880-0.302602.309201.83790HepG2SRFBP1
PSMG4ENSG00000180822.7364.74690223.368800.707403.347802.75250HepG2SRSF9
PSMG4ENSG00000180822.7335.85510501.47370-0.578305.784605.09510HepG2SSB
PSMG4ENSG00000180822.7371.50810485.43910-0.385902.614502.00620HepG2SUCLG1
PSMG4ENSG00000180822.7130.87780229.78730-0.812103.357502.62040HepG2SUPV3L1
PSMG4ENSG00000180822.7194.15300321.30470-0.726702.606501.56690HepG2TBRG4
PSMG4ENSG00000180822.7300.17820208.393300.526403.352002.74440HepG2TRIM56
PSMG4ENSG00000180822.7304.37970135.745601.164909.552608.14560HepG2UCHL5
PSMG4ENSG00000180822.7458.88350289.592300.664006.000505.17540HepG2UTP3
PSMG4ENSG00000180822.7154.86480239.73090-0.630402.781402.10740HepG2ZC3H8
PSMG4ENSG00000180822.7256.94430329.88990-0.360502.083801.59020HepG2ZNF622
PSMG4ENSG00000180822.7759.12910977.63210-0.364902.745402.09450K562AKAP8L
PSMG4ENSG00000180822.7825.811301202.89610-0.542605.160104.40150K562AQR
PSMG4ENSG00000180822.7814.21020970.81120-0.253802.108101.52670K562DDX47
PSMG4ENSG00000180822.7718.34720869.21280-0.275002.093701.45320K562EIF2S2
PSMG4ENSG00000180822.7474.44750634.49580-0.419402.933502.08820K562EIF4A3
PSMG4ENSG00000180822.7317.31920422.16710-0.411902.118001.36520K562FMR1
PSMG4ENSG00000180822.7310.90260434.04520-0.481402.259501.62880K562G3BP2
PSMG4ENSG00000180822.7822.723001037.54880-0.334702.197401.47250K562KIF1C
PSMG4ENSG00000180822.7900.245001162.31160-0.368602.894601.95920K562MBNL1
PSMG4ENSG00000180822.7562.52020814.69300-0.534403.213502.24840K562NAA15
PSMG4ENSG00000180822.7388.75060633.61500-0.704807.544305.54220K562NCBP2
PSMG4ENSG00000180822.7781.48580511.543300.611302.450401.53270K562PABPN1
PSMG4ENSG00000180822.7570.41750760.34000-0.414602.495801.70690K562PCBP3
PSMG4ENSG00000180822.7429.54170583.19970-0.441203.420802.52360K562POLR2G
PSMG4ENSG00000180822.7807.08090620.122100.380102.595701.80480K562PPIG
PSMG4ENSG00000180822.7335.84210581.21830-0.791306.991205.79980K562PRPF8
PSMG4ENSG00000180822.71095.385801449.22200-0.403802.386501.63020K562PUF60
PSMG4ENSG00000180822.7596.22260969.61800-0.701607.267706.43470K562PUS1
PSMG4ENSG00000180822.7622.89750944.68430-0.600807.588006.63600K562RBM15
PSMG4ENSG00000180822.7292.56310411.57400-0.492402.992301.60190K562RBM25
PSMG4ENSG00000180822.7416.59230591.92970-0.506803.008202.15650K562RPS19
PSMG4ENSG00000180822.7405.39900562.55450-0.472702.814101.78890K562SUPV3L1
PSMG4ENSG00000180822.7442.09890584.97420-0.404002.908202.06490K562SYNCRIP
PSMG4ENSG00000180822.7340.28470434.43340-0.352402.053501.36220K562U2AF2
PSMG4ENSG00000180822.7397.67140595.48990-0.582504.387603.07640K562UCHL5
PSMG4ENSG00000180822.7587.36230983.01550-0.743003.729102.15820K562UTP18
PSMG4ENSG00000180822.71097.264501355.06520-0.304502.302701.52760K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PSMG4 is not available on ENCORE database.





9 RBPs can affect the splicing of PSMG4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPSMG4ENSG00000180822.7chr6+3263917326399332591853259430326782432682830.065000.001230.02483includedK562SRSF1
SEPSMG4ENSG00000180822.7chr6+326391732639933259185325943032678243268283-0.064000.000030.00200excludedK562AKAP8L
SEPSMG4ENSG00000180822.7chr6+326444232645593263917326399332678243268015-0.099000.005230.09931excludedHepG2HNRNPK
SEPSMG4ENSG00000180822.7chr6+326444232645593263917326399332678243268015-0.374000.000850.01235excludedHepG2U2AF2
SEPSMG4ENSG00000180822.7chr6+326444232645593263917326399332678243268015-0.124000.000270.06000excludedK562HNRNPA1
SEPSMG4ENSG00000180822.7chr6+326391732639933259185325943032678243268283-0.102000.002280.09229excludedK562EFTUD2
SEPSMG4ENSG00000180822.7chr6+326440732645593263917326399332678243268154-0.333000.000030.01129excludedHepG2HNRNPUL1
SEPSMG4ENSG00000180822.7chr6+3264442326455932639173263993326782432680150.170000.000280.00897includedHepG2SRSF1
SEPSMG4ENSG00000180822.7chr6+326444232645593263917326399332678243268015-0.357000.000860.08474excludedHepG2RBFOX2
SEPSMG4ENSG00000180822.7chr6+326440732645593263917326399332678243268154-0.114000.001130.03062excludedK562AGGF1
SEPSMG4ENSG00000180822.7chr6+326444232645593263917326399332678243268015-0.155000.000010.00104excludedK562HNRNPK

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PSMG4 is not avaliable on ENCORE database.