PPT2-EGFL8

General Information

Gene Name       : PPT2-EGFL8
Gene ID             : ENSG00000258388.7
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PPT2-EGFL8)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PPT2-EGFL8ENSG00000258388.70.110.570.34ENCSR000AEF
HepG2PPT2-EGFL8ENSG00000258388.74.593.994.29ENCSR985KAT
K562PPT2-EGFL8ENSG00000258388.75.703.654.67ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PPT2-EGFL8 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PPT2-EGFL8 RNA is bound by 35 proteins.  







eCLIP assay for PPT2-EGFL8 is not avaliable on ENCORE database.





35 proteins are bound to PPT2-EGFL8 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr63213421132134294+3'-UTR,CDS,intron-Proximal3.7774713.49775K562DDX24
chr63213574332135843+3'-UTR3.372303.51117HepG2LSM11
chr63213471932134768+3'-UTR,CDS4.254499.85077HepG2PPIG
chr63213526932135336+3'-UTR,CDS,intron-Proximal3.742366.68812HepG2BUD13
chr63213425332134303+3'-UTR,CDS,intron-Proximal3.953598.24667K562BUD13
chr63213526832135328+3'-UTR,CDS,intron-Proximal4.086343.48187K562RBM15
chr63213526632135338+3'-UTR,CDS,intron-Proximal4.4790423.45468HepG2PRPF8
chr63213451832134576+3'-UTR,CDS3.505598.21285K562ZNF622
chr63213238832132448+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.5914810.18181HepG2PPIG
chr63213576232135806+3'-UTR4.104526.81381K562DDX24
chr63213569632135721+3'-UTR,CDS3.053363.84771K562ZNF622
chr63213423132134289+3'-UTR,CDS,intron-Proximal4.1620517.17730K562AQR
chr63213435732134436+3'-UTR,CDS,intron-Proximal4.9875511.58765HepG2PRPF8
chr63213451732134587+3'-UTR,CDS4.0736711.35339HepG2PPIG
chr63213491332134982+3'-UTR,CDS,intron-Proximal4.370294.78834HepG2PABPN1
chr63213229732132372+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.100328.17769HepG2PRPF4
chr63213405532134105+3'-UTR,intron-Proximal4.501078.01338K562AQR
chr63213034432130401+3'-UTR,CDS,intron-Proximal5.4486122.08597K562LIN28B
chr63213575232135867+3'-UTR3.8241216.19036K562ZNF622
chr63213405732134122+3'-UTR,intron-Distal,intron-Proximal3.454143.75624K562AKAP8L
chr63213527732135328+3'-UTR,CDS,intron-Proximal3.908534.05508K562U2AF1
chr63213589632135934+3'-UTR4.693015.29868K562UCHL5
chr63213415532134252+3'-UTR,intron-Distal,intron-Proximal4.207234.23812HepG2LSM11
chr63213476932134816+3'-UTR,CDS,intron-Proximal3.325887.02084HepG2PRPF8
chr63213469132134756+3'-UTR,CDS3.144585.71803K562UCHL5
chr63213419232134274+3'-UTR,intron-Proximal3.9910612.83233HepG2SF3B4
chr63213414532134191+3'-UTR,intron-Distal,intron-Proximal4.522936.11596HepG2PRPF4
chr63213035832130408+3'-UTR,CDS,intron-Proximal4.3574612.76865HepG2PPIG
chr63213390032133961+3'-UTR,5'-UTR,CDS,intron-Proximal3.250113.80334HepG2U2AF2
chr63213539532135427+3'-UTR,CDS,intron-Proximal3.750974.24993HepG2PPIG
chr63213414732134193+3'-UTR,intron-Distal,intron-Proximal3.386874.89070K562UCHL5
chr63213576332135823+3'-UTR3.222426.93851K562BUD13
chr63213536532135419+3'-UTR,CDS,intron-Proximal3.820493.56019HepG2GRWD1
chr63213527732135323+3'-UTR,CDS,intron-Proximal3.946777.39805K562DDX24
chr63213034432130408+3'-UTR,CDS,intron-Proximal4.0707321.08649K562DDX24
chr63213405932134142+3'-UTR,intron-Distal,intron-Proximal3.113974.26200K562GTF2F1
chr63213451232134567+3'-UTR,CDS5.091318.66757K562DDX24
chr63213577432135833+3'-UTR4.114403.53160K562RBFOX2
chr63213035732130400+3'-UTR,CDS,intron-Proximal3.6575311.07283HepG2LIN28B
chr63213401632134055+3'-UTR,CDS,intron-Proximal4.805338.52787K562AQR
chr63213528432135329+3'-UTR,CDS3.573676.00907HepG2PPIG
chr63213514232135211+3'-UTR,CDS,intron-Proximal3.030504.04186HepG2PPIG
chr63213453032134580+3'-UTR,CDS4.207696.81811K562UCHL5
chr63213034432130358+3'-UTR,CDS,intron-Proximal3.884415.40651HepG2PPIG
chr63213491132134960+3'-UTR,CDS,intron-Proximal3.098033.89560K562UCHL5
chr63213449932134587+3'-UTR,CDS4.220263.89619HepG2SRSF1
chr63213572832135846+3'-UTR,CDS3.206386.18332HepG2GRWD1
chr63213400832134016+3'-UTR,CDS,intron-Proximal5.317886.22530K562AQR
chr63213423632134336+3'-UTR,CDS,intron-Proximal3.044114.57360K562SRSF1
chr63213414032134211+3'-UTR,intron-Distal,intron-Proximal4.1542817.20091K562DDX24
chr63212567732125717+5'-UTR,CDS,intron-Distal,intron-Proximal4.184448.54394K562BUD13
chr63212236432122422+5'-UTR,CDS3.610267.30480HepG2DDX3X
chr63212234332122387+5'-UTR,CDS,intron-Proximal3.342335.28960K562AQR
chr63212568032125739+5'-UTR,CDS,intron-Distal,intron-Proximal6.2262211.46503HepG2PRPF8
chr63212372732123786+5'-UTR,CDS,intron-Proximal4.065465.93840HepG2PRPF8
chr63212567932125748+5'-UTR,CDS,intron-Distal,intron-Proximal4.3933914.50379K562PRPF8
chr63212541632125492+3'-UTR,5'-UTR,CDS3.346563.17744HepG2GRWD1
chr63212199332122033+5'-UTR,intron-Distal,intron-Proximal3.341083.42371HepG2DDX3X
chr63212203332122077+5'-UTR,intron-Distal,intron-Proximal4.317785.48791HepG2DDX3X
chr63212211232122176+5'-UTR,intron-Distal,intron-Proximal3.902243.56019HepG2GRWD1
chr63212562632125702+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.009495.01477K562UCHL5
chr63212561832125702+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.0510619.67801K562DDX24
chr63212543332125495+3'-UTR,5'-UTR,CDS3.8595511.99628K562DDX24
chr63212364732123680+5'-UTR,CDS,intron-Proximal3.299453.73413HepG2PPIG
chr63212561932125706+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.7570015.53747HepG2PPIG
chr63212543132125496+3'-UTR,5'-UTR,CDS3.029905.08732HepG2PPIG
chr63212375432123798+5'-UTR,CDS,intron-Proximal3.260319.68935K562AQR
chr63212249132122553+5'-UTR,CDS3.322804.24070HepG2GRWD1
chr63212243032122476+5'-UTR,CDS3.714253.70637K562DDX3X
chr63212271432122820+CDS,intron-Distal,intron-Proximal3.979196.08301HepG2EFTUD2
chr63212285232122905+CDS,intron-Distal3.154285.33841K562DDX24
chr63212255132122603+5'-UTR,CDS,intron-Proximal5.6293212.15317HepG2PRPF8
chr63212244632122516+5'-UTR,CDS3.472484.43584K562DROSHA
chr63212340132123483+5'-UTR,CDS,intron-Distal,intron-Proximal4.618725.32906HepG2AQR
chr63212280632122837+CDS,intron-Distal,intron-Proximal4.578285.79396K562DDX24
chr63212282732122864+CDS,intron-Distal3.159224.39623HepG2PPIG
chr63212250932122543+5'-UTR,CDS3.214553.43213K562UCHL5
chr63212338632123481+5'-UTR,CDS,intron-Distal,intron-Proximal3.3443812.18336K562AQR
chr63212250432122553+5'-UTR,CDS5.047588.08662K562DDX24
chr63212278532122827+CDS,intron-Distal,intron-Proximal3.384103.84119K562EFTUD2
chr63212295932123007+CDS,intron-Distal,intron-Proximal6.3451014.81397K562AQR
chr63212352532123561+CDS,intron-Proximal3.970446.08299HepG2PPIG
chr63213129832131399+3'-UTR,intron-Distal4.387685.14974HepG2UPF1
chr63213146532131569+intron-Distal3.485196.39223K562AKAP8L
chr63213221732132297+intron-Distal,intron-Proximal3.377726.96093HepG2PRPF4
chr63212260232122671+intron-Distal,intron-Proximal5.888708.93136HepG2EFTUD2
chr63213158232131675+intron-Distal4.394174.47026K562MATR3
chr63213374632133842+intron-Distal,intron-Proximal3.605383.00349HepG2ILF3
chr63213247832132622+intron-Distal,intron-Proximal3.493645.29595K562GTF2F1
chr63213073232130774+3'-UTR,intron-Distal3.922703.70369HepG2LIN28B
chr63213131532131393+3'-UTR,intron-Distal3.293876.72941K562FAM120A
chr63213058332130628+CDS,intron-Distal,intron-Proximal3.630224.36355HepG2LIN28B
chr63213363832133792+intron-Distal4.0575312.26770K562ILF3
chr63213257932132673+intron-Distal3.453344.84851K562ILF3
chr63213058232130606+CDS,intron-Distal,intron-Proximal4.531533.69113K562LIN28B
chr63213095832130996+3'-UTR,intron-Distal3.478715.84135HepG2PCBP2
chr63212270132122734+intron-Distal,intron-Proximal4.817064.47382K562EFTUD2
chr63213092332131006+3'-UTR,intron-Distal3.305583.50315HepG2UPF1
chr63213112732131210+3'-UTR,intron-Distal3.658859.31559HepG2PCBP2
chr63213054832130589+CDS,intron-Distal,intron-Proximal3.334664.64824K562PRPF8
chr63213114232131258+3'-UTR,intron-Distal3.956784.21448HepG2UPF1
chr63212580132125885+intron-Distal3.925633.34627K562HNRNPK
chr63212296332122996+intron-Distal,intron-Proximal4.054954.58287K562PRPF8
chr63213379232133870+intron-Distal,intron-Proximal3.234047.10959K562ILF3
chr63213368532133846+intron-Distal,intron-Proximal4.574566.53376K562FUS
chr63212266932122732+intron-Distal,intron-Proximal4.619353.70058HepG2XPO5
chr63213091232130957+3'-UTR,intron-Distal3.814928.88820HepG2PCBP2
chr63213082832130931+3'-UTR,intron-Distal4.4088012.80402HepG2LARP4
chr63213123732131393+3'-UTR,intron-Distal4.198308.49678HepG2AKAP1
chr63213063432130792+3'-UTR,CDS,intron-Distal3.826517.46994HepG2RPS3
chr63212337132123456+intron-Distal,intron-Proximal4.281644.00200K562EIF4G2
chr63213506832135111+intron-Proximal3.920753.56713HepG2SF3B4
chr63213041132130481+intron-Proximal3.674688.23725K562AQR
chr63213520732135263+intron-Proximal4.6922412.48497HepG2PRPF8
chr63212376432123809+intron-Proximal3.694134.77019K562BUD13
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PPT2-EGFL8 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PPT2-EGFL8 is not available on ENCORE database.

  • 33 RBPs can affect the levels of PPT2-EGFL8.  








The Knockdown/knockout RNA-Seq assay for PPT2-EGFL8 is not available on ENCORE database.





33 RBPs can affect the gene expression of PPT2-EGFL8 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PPT2-EGFL8ENSG00000258388.344.6540077.82140-0.801402.320301.71240HepG2DNAJC2
PPT2-EGFL8ENSG00000258388.3124.8784074.144800.752002.297301.75330HepG2EIF2S1
PPT2-EGFL8ENSG00000258388.3349.23610123.582401.498609.557908.55020HepG2ETF1
PPT2-EGFL8ENSG00000258388.350.76640104.25880-1.038203.780302.80320HepG2EWSR1
PPT2-EGFL8ENSG00000258388.3151.5457076.696300.982404.055503.25870HepG2G3BP1
PPT2-EGFL8ENSG00000258388.341.9397088.18260-1.072202.923102.21230HepG2HNRNPC
PPT2-EGFL8ENSG00000258388.334.1080087.60000-1.360805.324604.50510HepG2HNRNPU
PPT2-EGFL8ENSG00000258388.354.9821021.928201.326102.483801.77440HepG2NSUN2
PPT2-EGFL8ENSG00000258388.315.6151072.37740-2.212602.807202.09750HepG2RAVER1
PPT2-EGFL8ENSG00000258388.340.7493090.40280-1.149602.537301.52310HepG2RCC2
PPT2-EGFL8ENSG00000258388.344.0060086.55370-0.975902.499301.93310HepG2SF3B4
PPT2-EGFL8ENSG00000258388.356.4181090.98390-0.689501.994601.43420HepG2SMN1
PPT2-EGFL8ENSG00000258388.341.6977090.34530-1.115503.435502.92330HepG2SRSF1
PPT2-EGFL8ENSG00000258388.3119.1424073.502400.696702.099001.60460HepG2SRSF9
PPT2-EGFL8ENSG00000258388.3158.7120095.180600.737602.683601.82450HepG2TUFM
PPT2-EGFL8ENSG00000258388.360.40980111.44790-0.883503.199502.04880K562CCAR1
PPT2-EGFL8ENSG00000258388.3104.85750198.73120-0.922405.007203.00930K562DDX19B
PPT2-EGFL8ENSG00000258388.356.18990117.45690-1.063703.453901.30550K562DDX1
PPT2-EGFL8ENSG00000258388.398.58080148.70220-0.593002.188701.37650K562EFTUD2
PPT2-EGFL8ENSG00000258388.386.74360159.15690-0.875603.696102.48490K562EIF3D
PPT2-EGFL8ENSG00000258388.3172.9272085.453201.016902.413401.64590K562EIF4A3
PPT2-EGFL8ENSG00000258388.314.9616049.60510-1.729203.832302.97000K562G3BP2
PPT2-EGFL8ENSG00000258388.3116.89860209.53900-0.842005.018603.72280K562MBNL1
PPT2-EGFL8ENSG00000258388.3137.2231090.913500.593902.017401.32040K562PPIG
PPT2-EGFL8ENSG00000258388.361.40120144.70580-1.236805.420704.36690K562PRPF8
PPT2-EGFL8ENSG00000258388.3140.8475071.174900.984602.996602.05000K562PSIP1
PPT2-EGFL8ENSG00000258388.348.6683083.07010-0.771302.165001.56610K562PTBP1
PPT2-EGFL8ENSG00000258388.385.69200174.79560-1.028404.379603.71920K562PUS1
PPT2-EGFL8ENSG00000258388.3113.47130170.30760-0.585802.213801.67340K562RBM15
PPT2-EGFL8ENSG00000258388.3174.1520064.942301.423005.395903.31510K562SFPQ
PPT2-EGFL8ENSG00000258388.358.27290122.73700-1.074704.278002.67910K562SLBP
PPT2-EGFL8ENSG00000258388.3128.8896079.501700.697002.321301.57900K562TIA1
PPT2-EGFL8ENSG00000258388.394.89870177.21920-0.901102.828801.51740K562UTP18
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PPT2-EGFL8 is not available on ENCORE database.





4 RBPs can affect the splicing of PPT2-EGFL8 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A5SSPPT2-EGFL8ENSG00000258388.3chr6+321339143213405832133914321340093213427432134397-0.316000.000280.05471shorterK562HNRNPUL1
RIPPT2-EGFL8ENSG00000258388.3chr6+3213391432134397321339143213404332134274321343970.142000.000640.02796includedHepG2XRN2
MXEPPT2-EGFL8ENSG00000258388.3chr6+32132336321324583213391432134058321303443213039932134274321343970.449000.012030.073481includedK562AQR
MXEPPT2-EGFL8ENSG00000258388.3chr6+3213235532132458321339143213413132130344321303993213427432134397-0.445000.000700.020632includedK562TARDBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PPT2-EGFL8 is not avaliable on ENCORE database.