NAF1

General Information

Gene Name       : NAF1
Gene ID             : ENSG00000145414.8
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: NAF1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878NAF1ENSG00000145414.89.338.638.98ENCSR000AEF
HepG2NAF1ENSG00000145414.86.0010.448.22ENCSR985KAT
K562NAF1ENSG00000145414.815.0514.8014.93ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for NAF1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • NAF1 RNA is bound by 14 proteins.  







eCLIP assay for NAF1 is not avaliable on ENCORE database.





14 proteins are bound to NAF1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr4164050029164050158-3'-UTR,CDS,intron-Distal5.112104.97123HepG2PCBP2
chr4164049875164049986-3'-UTR,intron-Distal3.917293.47043HepG2KHSRP
chr4164087898164088037-5'-UTR,intron-Distal,intron-Proximal4.9426210.95413K562DDX3X
chr4164061487164061553-5'-UTR,CDS,intron-Distal,intron-Proximal3.275873.91614K562BUD13
chr4164085418164085526-CDS,intron-Distal3.007523.17744HepG2GRWD1
chr4164050440164050525-CDS,intron-Distal3.124343.80334HepG2U2AF2
chr4164050462164050523-CDS,intron-Distal4.145434.06574K562U2AF2
chr4164069491164069567-CDS,intron-Distal,intron-Proximal3.395613.66187K562ZNF622
chr4164050353164050407-CDS,intron-Distal4.321897.70265K562RBM15
chr4164050803164050916-intron-Distal4.740655.83754K562HNRNPM
chr4164061296164061370-intron-Distal,intron-Proximal3.451967.63715K562KHSRP
chr4164078607164078717-intron-Distal3.589424.52210K562KHSRP
chr4164037320164037430-intron-Distal4.050163.80954K562HNRNPL
chr4164054662164054769-intron-Distal4.4523510.06297K562KHSRP
chr4164051064164051171-intron-Distal4.558446.10662K562HNRNPM
chr4164045269164045288-intron-Distal5.0747716.36380K562XRCC6
chr4164047289164047363-intron-Distal4.799288.23960K562YBX3
chr4164051796164051926-intron-Distal4.009737.26586K562KHSRP
chr4164038737164038872-intron-Distal5.262666.58769K562EIF4G2
chr4164045288164045317-intron-Distal4.7113216.07223K562XRCC6
chr4164061227164061296-intron-Distal,intron-Proximal3.934768.44734K562KHSRP
chr4164059599164059736-intron-Distal3.748455.35459K562KHSRP
chr4164051926164051977-intron-Distal3.918093.45805K562KHSRP
chr4164058199164058315-intron-Distal,intron-Proximal3.030783.31456K562TIA1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for NAF1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for NAF1 is not available on ENCORE database.

  • 49 RBPs can affect the levels of NAF1.  








The Knockdown/knockout RNA-Seq assay for NAF1 is not available on ENCORE database.





49 RBPs can affect the gene expression of NAF1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
NAF1ENSG00000145414.4133.07560209.47500-0.654502.657001.88740HepG2ASCC1
NAF1ENSG00000145414.4185.26800331.27480-0.838405.261504.34220HepG2CPSF6
NAF1ENSG00000145414.4161.79710229.38860-0.503602.334001.73490HepG2CELF1
NAF1ENSG00000145414.489.19310149.71970-0.747302.867002.17790HepG2DDX21
NAF1ENSG00000145414.4219.82330376.18380-0.775102.718601.74980HepG2DDX59
NAF1ENSG00000145414.4116.45120208.31750-0.839103.584702.88930HepG2DDX6
NAF1ENSG00000145414.497.10600144.72080-0.575602.344701.73450HepG2DNAJC2
NAF1ENSG00000145414.495.36990200.27060-1.070305.422304.60970HepG2EIF2S1
NAF1ENSG00000145414.4104.47120221.32730-1.083105.971305.03510HepG2EIF4A3
NAF1ENSG00000145414.4139.69300207.14690-0.568402.148301.55980HepG2G3BP1
NAF1ENSG00000145414.4120.24270375.55080-1.6431015.6544014.24880HepG2GPKOW
NAF1ENSG00000145414.485.87270147.41630-0.779602.807502.15600HepG2HNRNPA1
NAF1ENSG00000145414.4181.29790358.39280-0.983207.062506.11020HepG2HNRNPLL
NAF1ENSG00000145414.4138.90070210.56300-0.600202.334001.70870HepG2IGF2BP2
NAF1ENSG00000145414.4216.75470365.45930-0.753603.703502.57240HepG2MTPAP
NAF1ENSG00000145414.4126.53770204.76670-0.694402.946302.20360HepG2PABPC4
NAF1ENSG00000145414.4141.57170233.46530-0.721703.668202.99330HepG2PUF60
NAF1ENSG00000145414.4151.70800234.54070-0.628502.888402.19220HepG2RPLP0
NAF1ENSG00000145414.4295.94060197.440400.583803.174502.67700HepG2SRSF1
NAF1ENSG00000145414.4219.10290349.25550-0.672703.145202.37750HepG2TARDBP
NAF1ENSG00000145414.479.40570158.28430-0.995204.972304.34220HepG2TIAL1
NAF1ENSG00000145414.4140.52230209.75860-0.577902.875302.16520HepG2UPF1
NAF1ENSG00000145414.4354.43840202.514800.807406.909606.03530HepG2UTP3
NAF1ENSG00000145414.4171.13180230.69530-0.430902.086101.59230HepG2ZNF622
NAF1ENSG00000145414.4665.95410378.188300.816208.557206.47120K562AARS
NAF1ENSG00000145414.4625.86160455.487700.458304.056903.39320K562AGGF1
NAF1ENSG00000145414.4603.52340473.951500.348602.036101.47290K562AKAP8L
NAF1ENSG00000145414.4531.62960793.60330-0.578002.562701.72420K562BOP1
NAF1ENSG00000145414.4499.26730843.86110-0.757208.749607.33870K562CPSF6
NAF1ENSG00000145414.4424.37900614.39700-0.533805.157204.21890K562EIF2S2
NAF1ENSG00000145414.4747.05890897.23950-0.264302.269501.41530K562EIF4G2
NAF1ENSG00000145414.4551.66330858.54450-0.638102.994602.10300K562FMR1
NAF1ENSG00000145414.4472.06040727.66610-0.624302.605901.72200K562FTO
NAF1ENSG00000145414.4500.28290385.881900.374502.458401.88140K562FXR1
NAF1ENSG00000145414.4404.55990805.70620-0.993908.860607.43180K562GPKOW
NAF1ENSG00000145414.4633.31700818.79250-0.370602.484301.76560K562GRSF1
NAF1ENSG00000145414.4242.36320413.66060-0.771306.007305.16120K562HNRNPC
NAF1ENSG00000145414.4534.02020720.24820-0.431603.395602.21020K562HNRNPL
NAF1ENSG00000145414.4506.34350786.44790-0.635203.032902.11400K562METAP2
NAF1ENSG00000145414.4752.74070956.35100-0.345402.335801.30310K562MSI2
NAF1ENSG00000145414.4524.32690662.71080-0.337903.054102.27340K562NSUN2
NAF1ENSG00000145414.4561.81260414.371300.439102.837001.84660K562PCBP2
NAF1ENSG00000145414.4466.30160350.540400.411602.084201.42930K562PRPF8
NAF1ENSG00000145414.4266.94110370.90880-0.474502.541101.68010K562PSIP1
NAF1ENSG00000145414.4596.72240452.399400.399402.900302.22290K562PTBP1
NAF1ENSG00000145414.4806.540701020.22340-0.339103.219902.18450K562PUM2
NAF1ENSG00000145414.4715.42360470.059300.605904.750904.06390K562PUS1
NAF1ENSG00000145414.4636.56780457.977600.474904.005703.30790K562RBM15
NAF1ENSG00000145414.4235.00160356.74130-0.602203.314902.28490K562TIAL1
NAF1ENSG00000145414.4182.14440359.20960-0.979707.506005.75740K562UCHL5
NAF1ENSG00000145414.4462.56980702.68630-0.603205.264704.30880K562UPF1
NAF1ENSG00000145414.4444.45510601.26650-0.436003.209002.27120K562WDR3
NAF1ENSG00000145414.4637.37330810.13170-0.346002.369801.58040K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for NAF1 is not available on ENCORE database.





9 RBPs can affect the splicing of NAF1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SENAF1ENSG00000145414.4chr4-1640543051640544081640498201640505001640583501640584020.123000.006350.09122includedHepG2U2AF1
SENAF1ENSG00000145414.4chr4-164066933164067016164061374164061535164069492164069706-0.143000.000000.00003excludedK562AQR
SENAF1ENSG00000145414.4chr4-164054305164054408164049820164050500164061374164061617-0.135000.002920.02994excludedK562AQR
SENAF1ENSG00000145414.4chr4-164066933164067016164061374164061535164069492164069586-0.278000.000000.00000excludedK562PUS1
SENAF1ENSG00000145414.4chr4-164079376164079479164078115164078606164085368164085543-0.530000.000430.00835excludedK562PUS1
SENAF1ENSG00000145414.4chr4-164054305164054408164049820164050500164058350164058402-0.169000.000320.04994excludedK562HNRNPM
SENAF1ENSG00000145414.4chr4-164066933164067016164061374164061535164069492164069586-0.099000.000920.05967excludedK562HNRNPL
SENAF1ENSG00000145414.4chr4-1640669331640670161640613741640615351640694921640695860.249000.000040.01741includedK562FXR2
SENAF1ENSG00000145414.4chr4-164066933164067016164061374164061535164069492164069586-0.154000.000160.00841excludedK562UTP18
SENAF1ENSG00000145414.4chr4-164066933164067016164061374164061535164069492164069586-0.117000.000810.02315excludedK562RBM15
SENAF1ENSG00000145414.4chr4-164066933164067016164061374164061535164069492164069586-0.103000.003420.07022excludedK562AGGF1
A3SSNAF1ENSG00000145414.4chr4-1640583501640585081640583501640584021640613741640616170.062000.000760.00544longerK562AQR
A3SSNAF1ENSG00000145414.4chr4-1640613741640615771640613741640615351640669331640670160.122000.000010.00014longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for NAF1 is not avaliable on ENCORE database.