MOB4

General Information

Gene Name       : MOB4
Gene ID             : ENSG00000115540.14
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: MOB4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MOB4ENSG00000115540.1410.7215.0612.89ENCSR000AEF
HepG2MOB4ENSG00000115540.1421.1045.6633.38ENCSR985KAT
K562MOB4ENSG00000115540.1412.7811.6912.23ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MOB4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MOB4 RNA is bound by 5 proteins.  







eCLIP assay for MOB4 is not avaliable on ENCORE database.





5 proteins are bound to MOB4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr2198400301198400405+3'-UTR,CDS,intron-Distal,intron-Proximal5.6733311.46503HepG2PRPF8
chr2198416071198416112+3'-UTR5.381094.57427HepG2PCBP2
chr2198400348198400392+3'-UTR,CDS,intron-Distal,intron-Proximal4.603134.22101K562PRPF8
chr2198400283198400356+3'-UTR,CDS,intron-Distal,intron-Proximal3.485655.56491HepG2BCLAF1
chr2198380842198380953+5'-UTR,CDS,intron-Distal,intron-Proximal5.7648412.84241HepG2PRPF8
chr2198380792198380888+5'-UTR,CDS,intron-Distal,intron-Proximal4.250414.61711HepG2NCBP2
chr2198380903198380985+5'-UTR,intron-Distal,intron-Proximal4.153156.49249HepG2EFTUD2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MOB4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MOB4 is not available on ENCORE database.

  • 58 RBPs can affect the levels of MOB4.  








The Knockdown/knockout RNA-Seq assay for MOB4 is not available on ENCORE database.





58 RBPs can affect the gene expression of MOB4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MOB4ENSG00000115540.10467.62360743.02300-0.668106.421504.85850HepG2AATF
MOB4ENSG00000115540.102254.552401663.401900.438601.790201.35240HepG2AKAP1
MOB4ENSG00000115540.101650.518801349.561400.290303.332902.59080HepG2AUH
MOB4ENSG00000115540.101273.14240937.171300.441903.130202.31440HepG2CALR
MOB4ENSG00000115540.10889.541801300.98230-0.548502.498301.57890HepG2CCAR1
MOB4ENSG00000115540.10350.91170717.04380-1.031005.778904.81860HepG2CPSF6
MOB4ENSG00000115540.101078.13130760.480700.503403.024101.58510HepG2CSTF2T
MOB4ENSG00000115540.101139.638901473.47510-0.370606.332305.27780HepG2DAZAP1
MOB4ENSG00000115540.10659.18700930.23660-0.496907.576306.56960HepG2DNAJC2
MOB4ENSG00000115540.10876.851801454.62400-0.730202.696602.06530HepG2EIF4A3
MOB4ENSG00000115540.101145.599401392.42520-0.281502.002001.30160HepG2EIF4G2
MOB4ENSG00000115540.101227.31960939.619800.385302.305701.59930HepG2FIP1L1
MOB4ENSG00000115540.10520.91850723.84550-0.474603.775402.86550HepG2FUBP3
MOB4ENSG00000115540.10375.15970812.91190-1.115604.825503.99560HepG2GPKOW
MOB4ENSG00000115540.10701.27220890.43450-0.344503.379502.59300HepG2HNRNPF
MOB4ENSG00000115540.10891.093501377.36930-0.628302.503501.83790HepG2HNRNPK
MOB4ENSG00000115540.101182.872701342.26880-0.182401.957001.37820HepG2HNRNPL
MOB4ENSG00000115540.10832.233901046.98480-0.331203.528302.85220HepG2HNRNPU
MOB4ENSG00000115540.10695.41610876.82490-0.334402.646701.93770HepG2IGF2BP1
MOB4ENSG00000115540.10750.349701069.46150-0.511209.047607.79840HepG2ILF2
MOB4ENSG00000115540.10877.760201345.75170-0.616502.170101.52560HepG2PABPC4
MOB4ENSG00000115540.101074.712201334.89290-0.312803.538202.87020HepG2PCBP1
MOB4ENSG00000115540.10695.73940933.82800-0.424603.970903.10360HepG2PPIL4
MOB4ENSG00000115540.101093.338101358.33610-0.313103.292202.70570HepG2PTBP1
MOB4ENSG00000115540.10770.25660938.03400-0.284301.848801.32380HepG2PUS1
MOB4ENSG00000115540.101027.549701471.04190-0.517607.069306.13750HepG2QKI
MOB4ENSG00000115540.102134.933001082.541700.979707.912206.75650HepG2RAVER1
MOB4ENSG00000115540.101599.716201295.068900.304703.310602.75790HepG2RBM22
MOB4ENSG00000115540.10990.886601335.09140-0.430104.278003.45430HepG2RBM25
MOB4ENSG00000115540.101121.722601511.67050-0.430406.090705.34050HepG2NELFE
MOB4ENSG00000115540.101063.265301407.96490-0.405105.477004.64610HepG2RECQL
MOB4ENSG00000115540.101049.65760806.926200.379302.099501.40610HepG2RRP9
MOB4ENSG00000115540.10644.15610932.39040-0.533507.868906.86530HepG2SAFB2
MOB4ENSG00000115540.101002.39000767.908200.384302.265001.62390HepG2SF3B1
MOB4ENSG00000115540.101016.181201337.19280-0.396006.338005.34490HepG2SLBP
MOB4ENSG00000115540.10884.155201087.33170-0.298403.535302.82280HepG2SMN1
MOB4ENSG00000115540.101927.37920854.414501.173509.854908.38820HepG2SNRNP70
MOB4ENSG00000115540.101736.651901462.736900.247502.931702.42050HepG2SRFBP1
MOB4ENSG00000115540.102184.737001476.084700.5656013.1062012.24190HepG2SRSF1
MOB4ENSG00000115540.101085.624701326.82890-0.289502.805202.24140HepG2TAF15
MOB4ENSG00000115540.10454.070501017.36760-1.1639023.9336022.73500HepG2TIAL1
MOB4ENSG00000115540.10509.327901026.43390-1.0110023.9574022.50080HepG2TRIM56
MOB4ENSG00000115540.10730.52390551.515600.405403.089502.38740HepG2ZC3H8
MOB4ENSG00000115540.10683.11280964.11630-0.497107.786906.99050HepG2ZNF622
MOB4ENSG00000115540.10916.04230728.727500.329902.201401.61690K562AKAP8L
MOB4ENSG00000115540.10189.98760477.25030-1.3288017.7835015.77590K562CPSF6
MOB4ENSG00000115540.101628.402401301.193200.323503.261602.20430K562CELF1
MOB4ENSG00000115540.10326.51290465.54110-0.511802.727201.69950K562EIF3D
MOB4ENSG00000115540.10348.24670533.77630-0.616102.362501.60230K562EIF4A3
MOB4ENSG00000115540.10931.85280605.402000.622103.551702.72750K562G3BP2
MOB4ENSG00000115540.10322.67210455.64590-0.497803.132502.29070K562GPKOW
MOB4ENSG00000115540.10648.88950826.10330-0.348302.484001.76550K562GRSF1
MOB4ENSG00000115540.10534.00680706.50290-0.403802.970301.87190K562HNRNPL
MOB4ENSG00000115540.10570.17550423.130700.430202.423601.72020K562PRPF8
MOB4ENSG00000115540.10242.34720406.48250-0.746105.362804.04880K562PSIP1
MOB4ENSG00000115540.101683.602301228.143600.455005.713304.13540K562PUM1
MOB4ENSG00000115540.10978.565501203.44080-0.298402.508101.59250K562PUM2
MOB4ENSG00000115540.101103.30010722.766500.610104.259903.60820K562PUS1
MOB4ENSG00000115540.10897.72810704.170000.350302.889002.28420K562RBM15
MOB4ENSG00000115540.10262.29790370.88260-0.499802.888101.87460K562RCC2
MOB4ENSG00000115540.10688.00700430.991900.674705.154404.03700K562RPS19
MOB4ENSG00000115540.10279.34740410.78470-0.556302.903601.87530K562RPS3
MOB4ENSG00000115540.10614.83620432.618000.507002.607901.32200K562RRP9
MOB4ENSG00000115540.10447.13350579.70670-0.374602.586401.79720K562SF3A3
MOB4ENSG00000115540.10242.08960351.58470-0.538302.896001.84030K562SRFBP1
MOB4ENSG00000115540.10857.29750673.001200.349102.595501.90810K562SRSF1
MOB4ENSG00000115540.10284.71940390.96580-0.457502.242301.40690K562TIAL1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MOB4 is not available on ENCORE database.





7 RBPs can affect the splicing of MOB4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMOB4ENSG00000115540.10chr2+198388347198388410198380555198380870198400253198400354-0.147000.000000.00015excludedK562AKAP8L
SEMOB4ENSG00000115540.10chr2+1983883471983884101983805551983808701984002531984003540.066000.001160.08176includedHepG2TBRG4
SEMOB4ENSG00000115540.10chr2+1983883471983884101983805551983808701984002531984003540.083000.000010.00233includedHepG2DDX3X
SEMOB4ENSG00000115540.10chr2+198388347198388410198380555198380870198400253198400354-0.153000.000000.00003excludedK562PUS1
SEMOB4ENSG00000115540.10chr2+1983883471983884101983805551983808701984002531984003540.092000.000900.06058includedHepG2IGF2BP3
SEMOB4ENSG00000115540.10chr2+198388347198388410198380555198380870198400253198400354-0.140000.000000.00284excludedHepG2GRSF1
MXEMOB4ENSG00000115540.10chr2+1984002531984003541984130591984131391983807701983808701984149981984151100.133000.000420.010421includedK562PUS1
MXEMOB4ENSG00000115540.10chr2+1984002361984003541984048341984048771983883471983884101984050741984051610.074000.015090.087991includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MOB4 is not avaliable on ENCORE database.