LRR1

General Information

Gene Name       : LRR1
Gene ID             : ENSG00000165501.16
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: LRR1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878LRR1ENSG00000165501.1631.7528.0529.90ENCSR000AEF
HepG2LRR1ENSG00000165501.1613.0616.2514.66ENCSR985KAT
K562LRR1ENSG00000165501.1622.9617.8520.41ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for LRR1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • LRR1 RNA is bound by 3 proteins.  







eCLIP assay for LRR1 is not avaliable on ENCORE database.





3 proteins are bound to LRR1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr145006569150065774+5'-UTR,CDS5.645158.43873K562DDX3X
chr145006572150065803+5'-UTR,CDS3.878833.48187K562RBM15
chr145006577450065851+CDS4.532708.39621K562DDX3X
chr145006591450066000+CDS,intron-Proximal4.681374.48002K562AQR
chr145006921450069310+intron-Distal,intron-Proximal4.118605.47926K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for LRR1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for LRR1 is not available on ENCORE database.

  • 63 RBPs can affect the levels of LRR1.  








The Knockdown/knockout RNA-Seq assay for LRR1 is not available on ENCORE database.





63 RBPs can affect the gene expression of LRR1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
LRR1ENSG00000165501.12153.75790237.63810-0.628103.525402.76720HepG2AUH
LRR1ENSG00000165501.1289.59940156.99350-0.809102.968502.03600HepG2BCLAF1
LRR1ENSG00000165501.1259.09170102.48300-0.794402.212201.67180HepG2BOP1
LRR1ENSG00000165501.1266.97050112.49290-0.748202.286701.57990HepG2CALR
LRR1ENSG00000165501.1294.66940148.03750-0.645002.677302.02050HepG2CKAP4
LRR1ENSG00000165501.1249.1136094.08790-0.937902.558501.89310HepG2CPSF6
LRR1ENSG00000165501.12147.64440205.81860-0.479201.955801.39740HepG2CELF1
LRR1ENSG00000165501.12152.21920221.29270-0.539802.714401.97910HepG2DAZAP1
LRR1ENSG00000165501.12111.30110177.66330-0.674702.387001.66300HepG2DDX55
LRR1ENSG00000165501.1252.64430106.84280-1.021102.734301.76200HepG2DDX59
LRR1ENSG00000165501.1262.92400114.54210-0.864202.502601.91360HepG2DDX6
LRR1ENSG00000165501.1250.01800110.08460-1.138103.856303.16330HepG2EIF2S1
LRR1ENSG00000165501.1276.78390121.64300-0.663801.883601.35200HepG2EIF4A3
LRR1ENSG00000165501.12150.58340272.82920-0.857405.688504.87830HepG2ETF1
LRR1ENSG00000165501.12102.79250153.55150-0.579002.427101.75260HepG2HNRNPF
LRR1ENSG00000165501.12133.35220201.57680-0.596102.867802.18390HepG2HNRNPL
LRR1ENSG00000165501.1244.59030101.79070-1.190803.742803.02050HepG2HNRNPLL
LRR1ENSG00000165501.12129.2523076.568300.755302.562601.64600HepG2HNRNPM
LRR1ENSG00000165501.1294.91650151.20220-0.671702.856502.12080HepG2IGF2BP1
LRR1ENSG00000165501.12184.72510122.816100.588802.014001.45040HepG2MAGOH
LRR1ENSG00000165501.1262.85240112.54350-0.840402.645401.93830HepG2PABPC4
LRR1ENSG00000165501.1265.54400117.62820-0.843702.658201.63950HepG2PCBP2
LRR1ENSG00000165501.1268.27260137.01730-1.005003.806302.87790HepG2PRPF8
LRR1ENSG00000165501.12151.56350222.20350-0.552002.396501.77200HepG2PUM2
LRR1ENSG00000165501.1293.90370148.39750-0.660202.282601.70520HepG2QKI
LRR1ENSG00000165501.12157.37630228.03700-0.535002.512802.01290HepG2RBM22
LRR1ENSG00000165501.1285.78870134.68800-0.650802.091201.49950HepG2RBM25
LRR1ENSG00000165501.1246.40600165.44560-1.8340011.9858010.73750HepG2RPLP0
LRR1ENSG00000165501.1254.58710111.53080-1.030803.301202.26930HepG2RPS10
LRR1ENSG00000165501.1239.3879075.06210-0.930302.310601.74320HepG2RPS19
LRR1ENSG00000165501.1253.45500135.53500-1.342305.578704.49790HepG2RRP9
LRR1ENSG00000165501.1258.06690100.75730-0.795102.192401.55960HepG2SF3B1
LRR1ENSG00000165501.12142.40820200.86010-0.496202.130901.50170HepG2SLBP
LRR1ENSG00000165501.1265.79780115.87270-0.816402.614701.68610HepG2SMNDC1
LRR1ENSG00000165501.12105.67320257.56350-1.2853011.2490010.42320HepG2SRFBP1
LRR1ENSG00000165501.12221.83440148.912600.574902.653202.18740HepG2SRSF1
LRR1ENSG00000165501.12125.30990206.82860-0.722903.830703.11510HepG2SRSF5
LRR1ENSG00000165501.1288.55970150.86690-0.768603.659902.87620HepG2SRSF7
LRR1ENSG00000165501.1265.93550121.15440-0.877703.429902.82890HepG2SRSF9
LRR1ENSG00000165501.1261.62410176.85080-1.521007.982606.92900HepG2SUPV3L1
LRR1ENSG00000165501.1249.4456099.19310-1.004402.969202.22110HepG2TARDBP
LRR1ENSG00000165501.1267.88640118.53060-0.804102.408101.47000HepG2TFIP11
LRR1ENSG00000165501.1244.82680116.56590-1.378706.295705.59710HepG2TIAL1
LRR1ENSG00000165501.1229.9330090.97970-1.603803.176402.11780HepG2U2AF2
LRR1ENSG00000165501.1267.75560112.15640-0.727102.480301.81270HepG2UPF1
LRR1ENSG00000165501.1257.19620123.35060-1.108805.260704.56800HepG2ZNF622
LRR1ENSG00000165501.12174.59960267.15940-0.613703.404002.78700K562AGGF1
LRR1ENSG00000165501.12715.59270533.192400.424402.788201.54490K562APOBEC3C
LRR1ENSG00000165501.12411.00080568.24120-0.467402.071501.54930K562AQR
LRR1ENSG00000165501.12348.09700238.680900.544302.552401.32840K562EEF2
LRR1ENSG00000165501.12312.72940228.264300.454102.095301.39560K562EIF3G
LRR1ENSG00000165501.12448.45730237.056600.919609.827708.76860K562FXR1
LRR1ENSG00000165501.12321.33310219.643900.548802.494501.82840K562G3BP2
LRR1ENSG00000165501.12302.60070213.704500.501702.463201.89630K562HNRNPC
LRR1ENSG00000165501.12282.68250382.74530-0.437202.618401.74900K562HNRNPU
LRR1ENSG00000165501.12110.96990201.44530-0.860202.539801.60190K562PABPN1
LRR1ENSG00000165501.12429.28880224.414500.935707.453606.22330K562PRPF8
LRR1ENSG00000165501.12426.08390300.815600.502203.517702.77970K562PTBP1
LRR1ENSG00000165501.12871.56790659.297600.402602.704101.89700K562PUF60
LRR1ENSG00000165501.12884.25870701.244600.334502.445601.44690K562PUM1
LRR1ENSG00000165501.12171.06780275.69010-0.688503.507602.90710K562PUS1
LRR1ENSG00000165501.12326.76220228.593900.515402.347801.59790K562RPS19
LRR1ENSG00000165501.12141.65730228.64380-0.690703.128702.21800K562SF3B4
LRR1ENSG00000165501.12118.86650211.55410-0.831702.470601.33770K562SNRNP200
LRR1ENSG00000165501.12307.46160196.480600.645904.013103.01850K562SYNCRIP
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for LRR1 is not available on ENCORE database.





7 RBPs can affect the splicing of LRR1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SELRR1ENSG00000165501.12chr14+500741175007483950069087500691865008097350081390-0.301000.001380.04048excludedK562AKAP8L
SELRR1ENSG00000165501.12chr14+5007026950070336500690875006918650080973500813890.270000.002180.02356includedK562AQR
SELRR1ENSG00000165501.12chr14+500702695007033650069087500691865007411750074839-0.287000.003350.09606excludedK562FXR1
SELRR1ENSG00000165501.12chr14+500702695007033650069087500691865007411750074839-0.239000.000070.00635excludedK562EFTUD2
SELRR1ENSG00000165501.12chr14+5006825950068367500656695006592150069087500691860.073000.001330.04649includedK562HNRNPU
SELRR1ENSG00000165501.12chr14+5007411750074839500690875006918650080973500813900.282000.000690.02837includedK562HNRNPU
SELRR1ENSG00000165501.12chr14+500741175007483950069087500691865008097350081390-0.390000.000710.02104excludedK562RBM15
SELRR1ENSG00000165501.12chr14+5007026950070336500690875006918650074117500748390.760000.000000.00001includedHepG2HNRNPC
SELRR1ENSG00000165501.12chr14+5007026950070336500690875006918650074117500748390.485000.000000.00000includedK562HNRNPC
MXELRR1ENSG00000165501.12chr14+50070269500703365007411750074839500690875006918650080973500813890.531000.000000.000281includedHepG2HNRNPC
MXELRR1ENSG00000165501.12chr14+50070269500703365007411750074839500690875006918650080973500813890.397000.000060.002001includedK562HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for LRR1 is not avaliable on ENCORE database.