EXTL2

General Information

Gene Name       : EXTL2
Gene ID             : ENSG00000162694.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: EXTL2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878EXTL2ENSG00000162694.1311.6712.9312.30ENCSR000AEF
HepG2EXTL2ENSG00000162694.139.2918.8914.09ENCSR985KAT
K562EXTL2ENSG00000162694.1314.7314.2814.50ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for EXTL2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • EXTL2 RNA is bound by 3 proteins.  







eCLIP assay for EXTL2 is not avaliable on ENCORE database.





3 proteins are bound to EXTL2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1101343413101343474-3'-UTR,CDS,intron-Distal,intron-Proximal4.616374.79708HepG2U2AF2
chr1101343955101344080-3'-UTR,CDS,intron-Distal,intron-Proximal3.567417.15738HepG2U2AF2
chr1101360156101360235-5'-UTR,intron-Distal,intron-Proximal3.687516.04280HepG2PRPF8
chr1101339916101340021-CDS,intron-Distal3.381634.57751HepG2U2AF2
chr1101353814101353889-intron-Distal,intron-Proximal3.890583.57189K562ILF3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for EXTL2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for EXTL2 is not available on ENCORE database.

  • 64 RBPs can affect the levels of EXTL2.  








The Knockdown/knockout RNA-Seq assay for EXTL2 is not available on ENCORE database.





64 RBPs can affect the gene expression of EXTL2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
EXTL2ENSG00000162694.9691.06780480.691100.523606.196705.36000HepG2ACO1
EXTL2ENSG00000162694.91183.30250768.969100.621704.974804.28790HepG2AKAP1
EXTL2ENSG00000162694.9580.88860453.824200.356002.112001.43140HepG2CALR
EXTL2ENSG00000162694.9782.12500604.496300.371602.262801.55940HepG2CIRBP
EXTL2ENSG00000162694.9270.10810380.18700-0.493202.581701.91410HepG2CPSF6
EXTL2ENSG00000162694.9398.50050540.60790-0.440003.329502.21350HepG2YBX3
EXTL2ENSG00000162694.9396.24670598.72510-0.595502.621001.36670HepG2DDX27
EXTL2ENSG00000162694.9951.74880736.641700.369502.229601.66230HepG2DDX3X
EXTL2ENSG00000162694.9462.75070632.72580-0.451302.452501.86820HepG2DDX6
EXTL2ENSG00000162694.9377.07950530.88240-0.493503.579802.78590HepG2DNAJC21
EXTL2ENSG00000162694.9418.28950526.12780-0.330902.638902.00000HepG2DNAJC2
EXTL2ENSG00000162694.9349.61750654.51410-0.904606.587805.55840HepG2EIF4B
EXTL2ENSG00000162694.9624.62840846.09780-0.437804.757103.70670HepG2EIF4G1
EXTL2ENSG00000162694.9185.29350629.20110-1.7637025.5642023.61260HepG2G3BP1
EXTL2ENSG00000162694.9385.17210501.22880-0.380002.983802.24110HepG2HNRNPF
EXTL2ENSG00000162694.9568.67180781.44390-0.458504.328903.49910HepG2HNRNPL
EXTL2ENSG00000162694.9403.34510592.20310-0.554105.981105.11810HepG2HNRNPU
EXTL2ENSG00000162694.9349.21450493.56260-0.499103.970403.11640HepG2IGF2BP1
EXTL2ENSG00000162694.9399.16140639.58670-0.680205.445304.52640HepG2IGF2BP2
EXTL2ENSG00000162694.9473.33840604.91960-0.353903.435002.62460HepG2ILF2
EXTL2ENSG00000162694.9524.47200678.45970-0.371401.977401.41850HepG2MAGOH
EXTL2ENSG00000162694.9525.67510850.57620-0.694309.251807.88410HepG2NOL12
EXTL2ENSG00000162694.9266.79980364.68330-0.450901.979601.34160HepG2NSUN2
EXTL2ENSG00000162694.9393.98170528.20170-0.423002.162101.50280HepG2PPIL4
EXTL2ENSG00000162694.9440.18610811.89510-0.8832011.9736010.85390HepG2PUF60
EXTL2ENSG00000162694.91051.31580861.798900.286702.733002.14320HepG2PUM1
EXTL2ENSG00000162694.9283.56720561.19380-0.984805.722204.73130HepG2RAVER1
EXTL2ENSG00000162694.9326.98830540.01660-0.723806.485305.50290HepG2RPLP0
EXTL2ENSG00000162694.9302.71070527.39610-0.8009010.270709.15110HepG2SAFB2
EXTL2ENSG00000162694.9588.71520719.45070-0.289302.179801.64580HepG2SF3B4
EXTL2ENSG00000162694.9586.83440778.35030-0.407504.068003.24070HepG2SLBP
EXTL2ENSG00000162694.9399.68190615.05490-0.621907.998106.99520HepG2SMN1
EXTL2ENSG00000162694.9383.36580572.29780-0.578003.319302.26020HepG2SMNDC1
EXTL2ENSG00000162694.9734.47500974.78890-0.408404.487203.89350HepG2SRFBP1
EXTL2ENSG00000162694.9509.94350610.92970-0.260701.822901.35720HepG2SRSF9
EXTL2ENSG00000162694.9220.24380352.22030-0.677403.367702.00800HepG2STAU1
EXTL2ENSG00000162694.9247.52410356.07580-0.524602.827801.87840HepG2SUPT6H
EXTL2ENSG00000162694.9389.23250636.96430-0.710604.613603.77350HepG2SUPV3L1
EXTL2ENSG00000162694.9294.16370575.51890-0.9682012.5662011.63350HepG2TIAL1
EXTL2ENSG00000162694.9414.82810580.57460-0.485004.784904.08440HepG2TRIM56
EXTL2ENSG00000162694.9461.36480627.02000-0.442602.098101.45890HepG2XRN2
EXTL2ENSG00000162694.9314.80130513.99010-0.707307.488806.62030K562AGGF1
EXTL2ENSG00000162694.9386.74560534.81410-0.467703.277002.56440K562AKAP8L
EXTL2ENSG00000162694.9645.21930939.71030-0.542404.747104.01580K562AQR
EXTL2ENSG00000162694.9386.57980491.48150-0.346402.298701.42570K562BCLAF1
EXTL2ENSG00000162694.9253.47460345.35540-0.446202.400401.66520K562CPSF6
EXTL2ENSG00000162694.9993.584201218.43620-0.294302.244901.36590K562CELF1
EXTL2ENSG00000162694.9511.75110629.58520-0.299002.141201.55650K562DDX47
EXTL2ENSG00000162694.9396.65210515.10410-0.377002.695801.90910K562EIF3G
EXTL2ENSG00000162694.9268.67690381.23780-0.504802.913901.72190K562EIF4B
EXTL2ENSG00000162694.9266.34010369.54020-0.472502.625001.37140K562EWSR1
EXTL2ENSG00000162694.9196.26260604.81710-1.6237027.5423023.47810K562G3BP1
EXTL2ENSG00000162694.9677.92700505.380800.423702.164801.55060K562G3BP2
EXTL2ENSG00000162694.9671.64590872.11220-0.376802.635901.89730K562GRSF1
EXTL2ENSG00000162694.9441.72220632.67530-0.518303.074901.97240K562IGF2BP2
EXTL2ENSG00000162694.9432.29270567.62720-0.392902.805701.97390K562KIF1C
EXTL2ENSG00000162694.9528.03130663.49070-0.329502.127101.32750K562MATR3
EXTL2ENSG00000162694.9221.61630321.84920-0.538302.940902.03590K562METAP2
EXTL2ENSG00000162694.9353.52460457.13010-0.370802.368001.61950K562MTPAP
EXTL2ENSG00000162694.9383.64760507.91950-0.404803.337102.52450K562NSUN2
EXTL2ENSG00000162694.9200.95870369.80850-0.879903.578302.41230K562PABPN1
EXTL2ENSG00000162694.91448.105301150.032300.332403.244002.08480K562PUM1
EXTL2ENSG00000162694.9275.33510530.50260-0.946209.197708.25650K562PUS1
EXTL2ENSG00000162694.9332.37360516.80060-0.636805.482204.67210K562RBM15
EXTL2ENSG00000162694.9400.59020619.35040-0.628605.581204.33820K562RBM22
EXTL2ENSG00000162694.9363.26990525.75570-0.533404.374003.29010K562SF3B4
EXTL2ENSG00000162694.9461.32400598.07760-0.374602.315901.36950K562SRSF5
EXTL2ENSG00000162694.9303.90270398.06910-0.389402.533801.41720K562SRSF7
EXTL2ENSG00000162694.9488.41590640.87620-0.391902.427801.76260K562TARDBP
EXTL2ENSG00000162694.9330.62570537.75930-0.701802.947101.59890K562UTP18
EXTL2ENSG00000162694.9789.201101058.72030-0.423903.772402.73620K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for EXTL2 is not available on ENCORE database.





7 RBPs can affect the splicing of EXTL2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEEXTL2ENSG00000162694.9chr1-101354308101354384101343031101343459101360188101360237-0.239000.006010.08538excludedK562SF3B4
SEEXTL2ENSG00000162694.9chr1-101354308101354420101343031101343459101360188101360368-0.227000.005300.04879excludedK562AQR
SEEXTL2ENSG00000162694.9chr1-101342349101342420101339715101339986101343031101343459-0.107000.001900.02101excludedK562AQR
SEEXTL2ENSG00000162694.9chr1-1013415881013418311013391111013399861013423491013424200.108000.000470.07935includedK562APOBEC3C
SEEXTL2ENSG00000162694.9chr1-1013415881013417621013379421013399861013423491013424200.094000.004610.08325includedHepG2SRSF1
SEEXTL2ENSG00000162694.9chr1-101354308101354384101343031101343459101360188101360237-0.352000.000030.00107excludedK562U2AF2
SEEXTL2ENSG00000162694.9chr1-101354308101354384101343371101343459101360188101360220-0.324000.003310.06723excludedK562RBM15
SEEXTL2ENSG00000162694.9chr1-101354308101354384101343371101343459101360188101360220-0.227000.002080.07791excludedK562HNRNPK

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for EXTL2 is not avaliable on ENCORE database.