CHMP7

General Information

Gene Name       : CHMP7
Gene ID             : ENSG00000147457.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CHMP7)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CHMP7ENSG00000147457.1329.8429.7629.80ENCSR000AEF
HepG2CHMP7ENSG00000147457.1316.5817.2116.89ENCSR985KAT
K562CHMP7ENSG00000147457.1321.2725.0323.15ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
CHMP7K562CRISPRBGKcLV37-5,BGKcLV37-6BGKcLV37-1,BGKcLV37-234.5,59.8NotSatisfiedENCORE2
CHMP7K562CRISPRBGKcLV46-5,BGKcLV46-6BGKcLV46-1,BGKcLV46-274.1,67.1ExperimentedENCORE2
CHMP7K562CRISPRBGKcLV46-7,BGKcLV46-8BGKcLV46-1,BGKcLV46-288.9,88.7ExperimentedENCORE2
CHMP7HepG2CRISPRBGHcLV36-11,BGHcLV36-12BGHcLV36-1,BGHcLV36-2NO CLEAR BAND ON THE POSITION,NotSatisfiedENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CHMP7 is not avaliable on ENCORE database.



Proteins bound to RNA
  • CHMP7 RNA is bound by 11 proteins.  







eCLIP assay for CHMP7 is not avaliable on ENCORE database.





11 proteins are bound to CHMP7 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr82311813223118191+3'-UTR6.3905127.30365K562PUM2
chr82311872323118794+3'-UTR5.315859.66188HepG2LIN28B
chr82311863423118706+3'-UTR4.942485.94928K562UPF1
chr82311907323119166+3'-UTR4.545374.85237K562UPF1
chr82311771523117832+3'-UTR,CDS3.241283.40321HepG2GRWD1
chr82311865223118795+3'-UTR3.832174.54434HepG2UPF1
chr82311872823118808+3'-UTR4.284467.70026K562LIN28B
chr82311554223115580+3'-UTR,CDS,intron-Proximal4.509895.18660HepG2PPIG
chr82310415423104254+5'-UTR,CDS3.570195.03370HepG2NCBP2
chr82310686623106955+5'-UTR,CDS,intron-Distal,intron-Proximal3.062835.76569HepG2PRPF8
chr82310417623104285+5'-UTR,CDS5.260879.60311HepG2DDX3X
chr82310419823104333+5'-UTR,CDS4.2701210.63326K562DDX3X
chr82310450423104603+CDS,intron-Distal,intron-Proximal3.892344.49024K562AQR
chr82310449223104594+CDS,intron-Distal,intron-Proximal4.803684.68690HepG2PRPF8
chr82310901423109099+intron-Distal3.767793.29248HepG2SUGP2
chr82310816623108222+intron-Distal4.440733.26170K562EIF4G2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CHMP7 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CHMP7 is not available on ENCORE database.

  • 41 RBPs can affect the levels of CHMP7.  








The Knockdown/knockout RNA-Seq assay for CHMP7 is not available on ENCORE database.





41 RBPs can affect the gene expression of CHMP7 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CHMP7ENSG00000147457.9889.34140634.674200.486606.519105.66660HepG2ACO1
CHMP7ENSG00000147457.91653.88700894.528800.8866010.098809.14830HepG2AKAP1
CHMP7ENSG00000147457.9837.80080639.098400.390502.804702.20250HepG2BOP1
CHMP7ENSG00000147457.9494.74390636.46450-0.363402.529201.79030HepG2CALR
CHMP7ENSG00000147457.9915.99500531.039400.786405.139604.09300HepG2CNOT7
CHMP7ENSG00000147457.9894.54460703.027000.347503.332102.63950HepG2CELF1
CHMP7ENSG00000147457.9766.74970544.767800.493003.183302.36220HepG2DDX55
CHMP7ENSG00000147457.91036.00130736.113200.492903.320002.65000HepG2DDX6
CHMP7ENSG00000147457.9418.19990572.10770-0.452103.062402.23830HepG2FUBP3
CHMP7ENSG00000147457.9565.10350731.90860-0.373102.048601.47300HepG2G3BP1
CHMP7ENSG00000147457.9598.47770777.05590-0.376702.278701.47440HepG2G3BP2
CHMP7ENSG00000147457.9431.02300665.15170-0.625904.360903.56930HepG2GPKOW
CHMP7ENSG00000147457.9605.35130793.71260-0.390802.142901.58350HepG2MATR3
CHMP7ENSG00000147457.9494.89450667.39520-0.431404.070703.15160HepG2PRPF4
CHMP7ENSG00000147457.9942.07250759.561300.310603.561902.90650HepG2PUM1
CHMP7ENSG00000147457.9894.41920525.739900.766504.381603.50530HepG2RAVER1
CHMP7ENSG00000147457.9980.34860763.028000.361503.113802.20870HepG2RBM15
CHMP7ENSG00000147457.9753.63440933.18620-0.308302.566102.06240HepG2RBM22
CHMP7ENSG00000147457.91070.75760845.592400.340502.432901.78570HepG2RPLP0
CHMP7ENSG00000147457.9461.88040699.09870-0.598003.121102.29030HepG2SNRNP70
CHMP7ENSG00000147457.91418.624401053.976500.428606.435105.75780HepG2SRFBP1
CHMP7ENSG00000147457.9745.90160915.06090-0.294902.842002.32420HepG2SSB
CHMP7ENSG00000147457.9532.53510736.22240-0.467302.943501.62200HepG2SSRP1
CHMP7ENSG00000147457.9548.77330757.10870-0.464304.464903.77870HepG2TAF15
CHMP7ENSG00000147457.9550.53050695.66330-0.337602.294701.53160HepG2TIA1
CHMP7ENSG00000147457.9965.91310739.823300.384602.526201.92360HepG2U2AF1
CHMP7ENSG00000147457.9488.45750659.67790-0.433504.259003.42260HepG2UPF1
CHMP7ENSG00000147457.9863.81910636.895100.439604.363303.63870HepG2UTP3
CHMP7ENSG00000147457.9946.42610725.521200.383404.902404.22700HepG2ZNF622
CHMP7ENSG00000147457.9853.92880676.595700.335702.348701.74550K562AKAP8L
CHMP7ENSG00000147457.9882.71980728.040600.277802.328001.53380K562DKC1
CHMP7ENSG00000147457.9394.84430551.20830-0.481302.889401.95440K562FTO
CHMP7ENSG00000147457.9736.89450559.301400.397703.560602.88760K562FXR1
CHMP7ENSG00000147457.9447.86010610.12140-0.446003.051302.21870K562GPKOW
CHMP7ENSG00000147457.9646.79680843.14660-0.382502.275901.52150K562PCBP3
CHMP7ENSG00000147457.9720.55840481.915200.580204.367303.42610K562PRPF8
CHMP7ENSG00000147457.9681.84110541.279500.333002.299901.68740K562PTBP1
CHMP7ENSG00000147457.9841.72460653.781600.364403.182702.55400K562RBM15
CHMP7ENSG00000147457.9693.40580519.022800.417802.977502.10280K562RBM22
CHMP7ENSG00000147457.9538.65450415.645400.373902.533601.71700K562SF3B4
CHMP7ENSG00000147457.9701.13300530.634300.401902.896202.17600K562SRSF1
CHMP7ENSG00000147457.9884.34050648.682600.447002.973202.11870K562SYNCRIP
CHMP7ENSG00000147457.9552.07330400.168900.464203.597202.67930K562U2AF2
CHMP7ENSG00000147457.9775.300801203.22910-0.634105.916104.57760K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CHMP7 is not available on ENCORE database.





6 RBPs can affect the splicing of CHMP7 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECHMP7ENSG00000147457.9chr8+231165782311663923116244231163432311765623117799-0.225000.000760.01356excludedK562PUS1
SECHMP7ENSG00000147457.9chr8+231165782311663923116244231163432311765623117799-0.246000.000220.01065excludedK562UTP18
SECHMP7ENSG00000147457.9chr8+231165782311663923116244231163432311765623117799-0.283000.000070.00335excludedK562AGGF1
SECHMP7ENSG00000147457.9chr8+231165782311663923116244231163432311765623117799-0.323000.000860.03592excludedK562SF3B1
A3SSCHMP7ENSG00000147457.9chr8+2311800923118100231180502311810023117623231178360.094000.000000.00000longerK562AQR
A3SSCHMP7ENSG00000147457.9chr8+2311655023116639231165782311663923116244231163430.068000.001720.01126longerK562AQR
MXECHMP7ENSG00000147457.9chr8+2311584223115962231162442311634323115545231155942311765623117836-0.234000.000230.007272includedHepG2SRSF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CHMP7 is not avaliable on ENCORE database.