AP4B1

General Information

Gene Name       : AP4B1
Gene ID             : ENSG00000134262.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: AP4B1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878AP4B1ENSG00000134262.1227.7524.9526.35ENCSR000AEF
HepG2AP4B1ENSG00000134262.125.719.197.45ENCSR985KAT
K562AP4B1ENSG00000134262.1219.2919.1519.22ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for AP4B1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • AP4B1 RNA is bound by 8 proteins.  







eCLIP assay for AP4B1 is not avaliable on ENCORE database.





8 proteins are bound to AP4B1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1114447278114447401-5'-UTR,CDS,intron-Distal4.364595.08313K562GRWD1
chr1114447382114447448-5'-UTR,intron-Distal,intron-Proximal3.046154.94677K562SMNDC1
chr1114447283114447421-5'-UTR,CDS,intron-Distal,intron-Proximal4.718826.35677K562SRSF1
chr1114445206114445268-CDS,intron-Distal,intron-Proximal3.223463.78727K562PRPF8
chr1114444482114444546-CDS,intron-Distal,intron-Proximal3.921476.67591K562SF3B4
chr1114441386114441509-CDS,intron-Distal,intron-Proximal5.018164.39274K562GPKOW
chr1114444469114444578-CDS,intron-Distal,intron-Proximal3.744588.40726K562SMNDC1
chr1114447186114447283-CDS,intron-Distal,intron-Proximal3.489648.38234K562UCHL5
chr1114445200114445251-intron-Distal,intron-Proximal4.390144.73315K562TIA1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for AP4B1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for AP4B1 is not available on ENCORE database.

  • 56 RBPs can affect the levels of AP4B1.  








The Knockdown/knockout RNA-Seq assay for AP4B1 is not available on ENCORE database.





56 RBPs can affect the gene expression of AP4B1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
AP4B1ENSG00000134262.8265.65190185.644600.516902.990902.36290HepG2ACO1
AP4B1ENSG00000134262.8464.66030164.922101.4943013.9123012.81490HepG2AKAP1
AP4B1ENSG00000134262.8241.52870136.450000.823704.169103.21350HepG2ASCC1
AP4B1ENSG00000134262.8278.66330129.639901.103907.383906.16780HepG2CIRBP
AP4B1ENSG00000134262.8250.72490168.036800.577201.981901.33930HepG2CNOT7
AP4B1ENSG00000134262.8343.05310258.340100.409101.986001.42450HepG2CELF1
AP4B1ENSG00000134262.8370.66140157.963201.2304010.128708.99770HepG2DDX3X
AP4B1ENSG00000134262.8193.66510130.444100.570001.973201.46300HepG2EIF2S1
AP4B1ENSG00000134262.8255.41760144.133800.825304.207803.42440HepG2EIF4A3
AP4B1ENSG00000134262.8235.27920140.377000.745002.852302.15460HepG2EIF4B
AP4B1ENSG00000134262.8376.19140274.058400.456902.451701.65590HepG2EIF4G1
AP4B1ENSG00000134262.8134.5189078.499000.777002.780301.99200HepG2FUBP3
AP4B1ENSG00000134262.8249.37810145.492400.777303.864303.05580HepG2FXR1
AP4B1ENSG00000134262.8242.27810134.930100.844404.407303.57610HepG2G3BP1
AP4B1ENSG00000134262.8222.52130143.291900.634902.651601.78120HepG2G3BP2
AP4B1ENSG00000134262.8241.85380136.711700.822904.150903.30970HepG2HNRNPK
AP4B1ENSG00000134262.8256.58280137.140900.903705.110604.21830HepG2IGF2BP2
AP4B1ENSG00000134262.8278.87830128.751601.114903.677102.54250HepG2IGF2BP3
AP4B1ENSG00000134262.8238.65940137.963900.790603.416802.28680HepG2KHSRP
AP4B1ENSG00000134262.8212.67000138.126200.622502.480001.41040HepG2LARP7
AP4B1ENSG00000134262.8241.59850145.543500.731103.413902.68530HepG2MAGOH
AP4B1ENSG00000134262.8304.96650146.347101.059206.555005.61590HepG2MATR3
AP4B1ENSG00000134262.8180.83650119.784900.594102.044701.34440HepG2MSI2
AP4B1ENSG00000134262.8342.11420149.785501.191509.061307.95410HepG2NCBP2
AP4B1ENSG00000134262.8284.70130133.352801.094107.527706.35070HepG2PABPC4
AP4B1ENSG00000134262.8219.06540153.603700.512002.460801.88080HepG2PCBP1
AP4B1ENSG00000134262.8254.36450156.302300.702502.575602.04470HepG2PTBP1
AP4B1ENSG00000134262.8141.23260262.99750-0.897004.774804.01760HepG2PUF60
AP4B1ENSG00000134262.8256.35780169.269000.598703.045602.39570HepG2QKI
AP4B1ENSG00000134262.8218.18530148.248300.557402.587601.75640HepG2RBM15
AP4B1ENSG00000134262.8453.51500285.305200.668505.460604.79480HepG2RBM22
AP4B1ENSG00000134262.8217.98540153.626400.504702.091101.49950HepG2RBM25
AP4B1ENSG00000134262.8271.84960173.945500.644103.642803.03910HepG2NELFE
AP4B1ENSG00000134262.8234.27190162.013800.532002.527801.93500HepG2RECQL
AP4B1ENSG00000134262.8131.32490219.53800-0.741303.682902.91320HepG2RPLP0
AP4B1ENSG00000134262.8275.47410178.278100.627702.813802.13420HepG2SF3A3
AP4B1ENSG00000134262.8439.46820322.223300.447602.889202.38040HepG2SRFBP1
AP4B1ENSG00000134262.8360.23410169.850301.0846010.615909.82180HepG2SRSF1
AP4B1ENSG00000134262.8249.52890152.677900.708604.300203.62490HepG2TAF15
AP4B1ENSG00000134262.8235.61060140.279800.748004.453903.40120HepG2TIA1
AP4B1ENSG00000134262.8203.69370126.637300.685602.480001.88330HepG2U2AF1
AP4B1ENSG00000134262.8267.69650152.645000.810305.622004.81710HepG2UTP3
AP4B1ENSG00000134262.8328.19600173.885900.916309.126708.28010HepG2ZNF622
AP4B1ENSG00000134262.81032.60470707.989400.544407.922607.03220K562AGGF1
AP4B1ENSG00000134262.8671.55110524.935900.355302.828101.30650K562AKAP1
AP4B1ENSG00000134262.81101.84720736.700500.580706.373205.35110K562AKAP8L
AP4B1ENSG00000134262.8927.28740772.986400.262502.138201.34250K562ATP5C1
AP4B1ENSG00000134262.81613.062601265.783300.349703.580502.46920K562CELF1
AP4B1ENSG00000134262.8585.44690454.645800.364702.628801.51570K562GLRX3
AP4B1ENSG00000134262.8517.72860391.360900.403602.401301.84010K562HNRNPC
AP4B1ENSG00000134262.8545.81250716.42990-0.392403.352702.37160K562HNRNPU
AP4B1ENSG00000134262.8687.04550477.997500.523305.675404.54360K562MTPAP
AP4B1ENSG00000134262.8548.06430385.342700.508103.303701.69200K562NUSAP1
AP4B1ENSG00000134262.8525.09370382.095000.458502.825801.38670K562PHF6
AP4B1ENSG00000134262.8840.726801123.26540-0.418003.025202.17160K562PUF60
AP4B1ENSG00000134262.81440.22240730.566100.9791015.4582014.21460K562PUS1
AP4B1ENSG00000134262.8967.01880711.858600.441904.717403.96340K562RBM15
AP4B1ENSG00000134262.8523.85930680.99330-0.378502.367501.71090K562TARDBP
AP4B1ENSG00000134262.8731.66420537.977700.443502.713301.63390K562U2AF1
AP4B1ENSG00000134262.8624.28730481.874000.373502.246601.45930K562WDR3
AP4B1ENSG00000134262.8618.50930501.077000.303702.379401.59020K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for AP4B1 is not available on ENCORE database.





9 RBPs can affect the splicing of AP4B1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEAP4B1ENSG00000134262.8chr1-114441746114441974114441339114441423114442525114442630-0.206000.000010.00030excludedK562SRSF1
SEAP4B1ENSG00000134262.8chr1-114441746114441974114441339114441423114442525114442630-0.185000.000330.01581excludedK562PRPF8
SEAP4B1ENSG00000134262.8chr1-1144417461144419741144413391144414231144425251144426300.142000.002580.02711includedK562AQR
SEAP4B1ENSG00000134262.8chr1-114441746114441974114441339114441423114442525114442630-0.154000.003030.08939excludedK562FXR1
SEAP4B1ENSG00000134262.8chr1-1144417461144419741144413391144414231144425251144426300.269000.000660.09514includedK562NSUN2
SEAP4B1ENSG00000134262.8chr1-1144417461144419741144413391144414231144425251144426300.445000.000020.00187includedK562HNRNPK
SEAP4B1ENSG00000134262.8chr1-114441746114441974114441339114441423114442525114442630-0.218000.000010.00059excludedK562PTBP1
A3SSAP4B1ENSG00000134262.8chr1-1144429521144430471144429521144430221144438571144440050.069000.001520.01009longerK562AQR
A3SSAP4B1ENSG00000134262.8chr1-1144413391144414531144413391144414231144425251144426460.117000.002060.01324longerK562AQR
A3SSAP4B1ENSG00000134262.8chr1-1144404611144406681144404611144405651144413391144414230.100000.000930.04604longerK562PUS1
A3SSAP4B1ENSG00000134262.8chr1-1144404611144406681144404611144405651144413391144414230.111000.001000.09527longerK562RBM15
MXEAP4B1ENSG00000134262.8chr1-1144388791144390871144404611144406681144383781144386601144413391144414230.107000.008910.057651includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for AP4B1 is not avaliable on ENCORE database.