AAMDC

General Information

Gene Name       : AAMDC
Gene ID             : ENSG00000087884.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: AAMDC)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878AAMDCENSG00000087884.141.525.673.59ENCSR000AEF
HepG2AAMDCENSG00000087884.1429.3129.9929.65ENCSR985KAT
K562AAMDCENSG00000087884.1410.047.278.65ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for AAMDC is not avaliable on ENCORE database.



Proteins bound to RNA
  • AAMDC RNA is bound by 3 proteins.  







eCLIP assay for AAMDC is not avaliable on ENCORE database.





3 proteins are bound to AAMDC RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr117758326577583383+3'-UTR,CDS,intron-Distal3.679754.91517HepG2LARP4
chr117753219377532297+5'-UTR,intron-Proximal4.030873.33043HepG2NCBP2
chr117756178877561905+intron-Distal4.2913216.79879HepG2HNRNPL
chr117756179277561939+intron-Distal6.0307718.41143K562HNRNPL
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for AAMDC is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for AAMDC is not available on ENCORE database.

  • 50 RBPs can affect the levels of AAMDC.  








The Knockdown/knockout RNA-Seq assay for AAMDC is not available on ENCORE database.





50 RBPs can affect the gene expression of AAMDC :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
AAMDCENSG00000087884.10159.72770294.29940-0.881705.329304.25620HepG2ASCC1
AAMDCENSG00000087884.10153.5455076.220601.010304.797803.81600HepG2CALR
AAMDCENSG00000087884.10206.84820131.332200.655302.880802.19020HepG2DDX21
AAMDCENSG00000087884.10192.07330128.588700.578802.363801.52490HepG2DDX24
AAMDCENSG00000087884.10238.74870133.843200.834805.289304.40740HepG2DKC1
AAMDCENSG00000087884.10142.27310302.75770-1.089506.123605.13100HepG2EIF4B
AAMDCENSG00000087884.10402.19820241.713500.734505.464604.34190HepG2EIF4G2
AAMDCENSG00000087884.10220.69910296.90230-0.427902.379101.81410HepG2ETF1
AAMDCENSG00000087884.10278.60060136.707701.027007.558306.18170HepG2EWSR1
AAMDCENSG00000087884.10169.01280291.02430-0.784004.433903.60040HepG2G3BP1
AAMDCENSG00000087884.10174.56190113.123200.625702.303401.70940HepG2HNRNPA1
AAMDCENSG00000087884.10142.24720294.78110-1.051207.110806.02840HepG2HNRNPK
AAMDCENSG00000087884.10154.99390232.94520-0.587802.960602.26530HepG2HNRNPL
AAMDCENSG00000087884.10149.61730315.62030-1.076907.022406.05240HepG2MATR3
AAMDCENSG00000087884.10177.70710287.64680-0.694803.676102.85110HepG2PABPC4
AAMDCENSG00000087884.10140.25660245.56680-0.808005.373204.57280HepG2PCBP1
AAMDCENSG00000087884.10172.79370256.99650-0.572703.208702.58090HepG2PUM1
AAMDCENSG00000087884.10181.02150256.80100-0.504502.214901.61220HepG2PUM2
AAMDCENSG00000087884.10163.83220270.61540-0.724004.271203.51960HepG2QKI
AAMDCENSG00000087884.10391.89760248.159900.659105.078104.43000HepG2RBM22
AAMDCENSG00000087884.10182.14880259.00460-0.507902.505901.91620HepG2RECQL
AAMDCENSG00000087884.10183.26990114.144600.683002.793302.10780HepG2RPLP0
AAMDCENSG00000087884.10157.53270260.14780-0.723704.309203.59500HepG2SF3B4
AAMDCENSG00000087884.1065.81720124.97710-0.925103.327102.26590HepG2SMNDC1
AAMDCENSG00000087884.10366.24080280.295400.385702.026301.57700HepG2SRFBP1
AAMDCENSG00000087884.10160.38560239.03870-0.575702.831702.19870HepG2SRSF5
AAMDCENSG00000087884.10499.96080243.376701.0385015.0468014.04320HepG2SSB
AAMDCENSG00000087884.10194.85650121.438400.682103.172902.64320HepG2TIAL1
AAMDCENSG00000087884.1077.25290122.55110-0.665702.417501.88320HepG2TRIM56
AAMDCENSG00000087884.10240.86430119.694401.008804.314903.04550HepG2UPF2
AAMDCENSG00000087884.1079.67800134.65090-0.757002.414001.42620HepG2XRCC6
AAMDCENSG00000087884.10255.36380128.714100.988304.765903.82340HepG2XRN2
AAMDCENSG00000087884.10273.91300140.458800.963507.822306.93700K562AGGF1
AAMDCENSG00000087884.10219.88750138.431000.667502.527701.96120K562AQR
AAMDCENSG00000087884.10126.3519073.853700.774602.500001.35260K562DDX21
AAMDCENSG00000087884.1048.5468095.53130-0.976602.085101.38700K562EIF3G
AAMDCENSG00000087884.1075.41900117.28410-0.637002.013101.31020K562EIF4A3
AAMDCENSG00000087884.10102.5092054.293300.916802.719601.87360K562FMR1
AAMDCENSG00000087884.10206.77030104.002700.991303.304702.48130K562GRSF1
AAMDCENSG00000087884.10236.29480130.804700.853102.848901.60900K562HNRNPA2B1
AAMDCENSG00000087884.10221.10070155.091000.511502.292401.55000K562KIF1C
AAMDCENSG00000087884.1092.46310154.97850-0.745103.159402.25940K562MAGOH
AAMDCENSG00000087884.1080.70790150.56980-0.899704.343503.52860K562PTBP1
AAMDCENSG00000087884.10295.69070144.907401.028907.099206.27540K562PUS1
AAMDCENSG00000087884.10193.88410141.226100.457101.929101.41830K562RBM15
AAMDCENSG00000087884.1023.2573054.45400-1.227402.532801.49910K562SAFB
AAMDCENSG00000087884.1059.26740108.94360-0.878303.226002.30160K562SF3B4
AAMDCENSG00000087884.1089.84920147.60630-0.716202.642401.95000K562SRSF1
AAMDCENSG00000087884.1027.4194061.30060-1.160702.771801.95170K562SYNCRIP
AAMDCENSG00000087884.10137.0897075.161100.867003.763802.93770K562UPF1
AAMDCENSG00000087884.10110.9565064.310900.786802.695401.82930K562WDR3
AAMDCENSG00000087884.10252.06590155.899100.693104.060002.98090K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for AAMDC is not available on ENCORE database.





10 RBPs can affect the splicing of AAMDC :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEAAMDCENSG00000087884.10chr11+775520647755210677532199775322877755352477553674-0.215000.002500.07310excludedK562PRPF8
SEAAMDCENSG00000087884.10chr11+7755206477552106775321997753228777553524775536740.240000.000310.03088includedHepG2TBRG4
SEAAMDCENSG00000087884.10chr11+7755206477552106775321997753228777553524775536740.202000.007440.07245includedHepG2U2AF2
SEAAMDCENSG00000087884.10chr11+775663907756652877553502775536747758076777580863-0.068000.000020.00033excludedK562AQR
SEAAMDCENSG00000087884.10chr11+7756639077566528775535247755367477580767775808630.056000.000130.01267includedHepG2NCBP2
SEAAMDCENSG00000087884.10chr11+7755206477552106775321997753228777553524775536740.259000.000820.03930includedHepG2SFPQ
SEAAMDCENSG00000087884.10chr11+7755206477552106775321997753228777553524775536740.268000.001360.08440includedHepG2TIAL1
SEAAMDCENSG00000087884.10chr11+7755206477552106775321997753228777553524775536740.202000.001070.08638includedHepG2SUPV3L1
SEAAMDCENSG00000087884.10chr11+7756639077566528775535247755367477580767775808630.201000.000000.00000includedHepG2HNRNPC
SEAAMDCENSG00000087884.10chr11+7755206477552106775321997753228777553524775536740.251000.000020.00302includedHepG2SRSF9
SEAAMDCENSG00000087884.10chr11+7756639077566528775535247755367477580767775808630.166000.000000.00004includedK562HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for AAMDC is not avaliable on ENCORE database.