ANXA2

General Information

Gene Name : ANXA2
Gene ID : ENSG00000182718.16
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: ANXA2)

Not Available

Antibody Validation

GeneTex: GTX100046

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	ANXA2	ENSG00000182718.16	225.12	220.70	222.91	ENCSR000AEF
HepG2	ANXA2	ENSG00000182718.16	565.83	527.15	546.49	ENCSR985KAT
K562	ANXA2	ENSG00000182718.16	393.46	389.40	391.43	ENCSR000AEO

Assays

1 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	ANXA2-BGHcLV12-HepG2	ENCSR862BCF	ANXA2	HepG2	Released		ENCSR827PII	CRISPR	KD% = 54.2,62.5

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
ANXA2	ENCAB049MLI	GTX100046	39476				BGHcLV12-3, Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
ANXA2	K562	shRNA			BGKLV38-9,BGKLV38-10	BGKLV38-1,BGKLV38-2	0.0,0.0	NotSatisfied	ENCODE3
ANXA2	K562	shRNA			BGKLV38-11,BGKLV38-12	BGKLV38-1,BGKLV38-2	0.0,0.0	NotSatisfied	ENCODE3
ANXA2	K562	shRNA			BGKLV38-13,BGKLV38-14	BGKLV38-1,BGKLV38-2	0.0,0.0	NotSatisfied	ENCODE3
ANXA2	HepG2	shRNA			BGHLV30-9,BGHLV30-10	BGHLV30-1,BGHLV30-2	0.0,0.0	NotSatisfied	ENCODE3
ANXA2	K562	CRISPR			BGKcLV11-7,BGKcLV11-8	BGKcLV11-1,BGKcLV11-2	0.0,0.0	NotSatisfied	ENCODE4
ANXA2	K562	CRISPR			BGKcLV11-9,BGKcLV11-10	BGKcLV11-1,BGKcLV11-2	0.0,0.0	NotSatisfied	ENCODE4
ANXA2	HepG2	CRISPR	ENCSR862BCF	ENCSR827PII	ANXA2-BGHcLV12-3,ANXA2-BGHcLV12-4	NT-BGHcLV12-1,NT-BGHcLV12-2	54.2,62.5	Released	ENCODE4
ANXA2	HepG2	CRISPR			BGHcLV12-5,BGHcLV12-6	BGHcLV12-1,BGHcLV12-2	56.8,64.9	NotSatisfied	ENCODE4

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
ANXA2	Product_ID: GTX100046 Lot_ID: 39476 Source: GeneTex Target Name: ANXA2-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for ANXA2 is not avaliable on ENCORE database.

Proteins bound to RNA

ANXA2 RNA is bound by 30 proteins.

CanvasJS.com

eCLIP assay for ANXA2 is not avaliable on ENCORE database.

30 proteins are bound to ANXA2 RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr15	60656676	60656687	-	3'-UTR,CDS,intron-Distal	5.09064	72.72730	K562	YBX3
chr15	60656671	60656676	-	3'-UTR,CDS,intron-Distal,intron-Proximal	5.23355	69.48374	K562	YBX3
chr15	60656687	60656703	-	3'-UTR,CDS,intron-Distal	4.38767	64.35839	K562	YBX3
chr15	60656667	60656671	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.93394	46.41005	K562	YBX3
chr15	60656663	60656667	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.72798	41.29321	K562	YBX3
chr15	60639593	60639683	-	3'-UTR,intron-Distal	5.51624	27.93867	HepG2	SUB1
chr15	60656628	60656659	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.27086	25.64461	K562	YBX3
chr15	60644502	60644569	-	intron-Distal,intron-Proximal	6.77856	21.90147	K562	AQR
chr15	60641883	60641958	-	intron-Distal	6.11290	15.10895	K562	PTBP1
chr15	60689460	60689496	-	5'-UTR,intron-Distal	4.73029	14.68502	K562	YBX3
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 74 entries

eCLIP assay for ANXA2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for ANXA2 is not available on ENCORE database.
154 RBPs can affect the levels of ANXA2.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for ANXA2 is not available on ENCORE database.

154 RBPs can affect the gene expression of ANXA2 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
ANXA2	ENSG00000182718.12	2768.57180	7229.38890	-1.38470	99.51910	97.47070	HepG2	NELFE
ANXA2	ENSG00000182718.12	2593.85300	5662.77400	-1.12640	79.46720	77.05210	HepG2	SUCLG1
ANXA2	ENSG00000182718.12	11714.65240	5419.03620	1.11210	77.44360	74.53960	K562	AGGF1
ANXA2	ENSG00000182718.12	3507.40590	7059.27500	-1.00910	63.44020	61.85160	HepG2	SRSF1
ANXA2	ENSG00000182718.12	1212.56800	2860.16300	-1.23800	56.51410	54.02170	HepG2	PRPF4
ANXA2	ENSG00000182718.12	9150.37410	4929.43790	0.89230	55.49830	53.99740	HepG2	SRFBP1
ANXA2	ENSG00000182718.12	3562.51990	6763.20200	-0.92480	47.64220	45.77930	HepG2	SF3B4
ANXA2	ENSG00000182718.12	539.40990	3275.91170	-2.60240	46.05010	43.58620	HepG2	RAVER1
ANXA2	ENSG00000182718.12	2218.98560	7452.86820	-1.74790	45.07560	43.31700	HepG2	AKAP1
ANXA2	ENSG00000182718.12	859.35780	2344.65510	-1.44800	45.14800	43.22040	HepG2	RPS19
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 183 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for ANXA2 is not available on ENCORE database.

18 RBPs can affect the splicing of ANXA2 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	ANXA2	ENSG00000182718.12	chr15	-	60674540	60674688			60656674	60656722	60678226	60678285	-0.08100	0.00000	0.00020	excluded	K562	SF3B4
SE	ANXA2	ENSG00000182718.12	chr15	-	60688349	60688626			60678226	60678285	60689456	60689537	0.19300	0.00000	0.00008	included	K562	PRPF8
SE	ANXA2	ENSG00000182718.12	chr15	-	60674540	60674640			60656627	60656722	60678226	60678285	-0.07700	0.00000	0.00000	excluded	K562	AQR
SE	ANXA2	ENSG00000182718.12	chr15	-	60674540	60674640			60656627	60656722	60678226	60678285	-0.06300	0.00000	0.00000	excluded	K562	U2AF1
SE	ANXA2	ENSG00000182718.12	chr15	-	60674540	60674623			60656674	60656722	60678226	60678285	-0.06800	0.00000	0.00000	excluded	K562	UTP18
SE	ANXA2	ENSG00000182718.12	chr15	-	60688349	60688626			60678226	60678285	60689456	60689537	0.20600	0.00000	0.00000	included	K562	U2AF2
MXE	ANXA2	ENSG00000182718.12	chr15	-	60653139	60653253	60656627	60656722	60649344	60649435	60678226	60678285	0.13100	0.00000	0.00000	1included	K562	U2AF1
MXE	ANXA2	ENSG00000182718.12	chr15	-	60653139	60653253	60656627	60656722	60649344	60649435	60678226	60678285	0.08400	0.00000	0.00000	1included	K562	AQR
MXE	ANXA2	ENSG00000182718.12	chr15	-	60688349	60688626	60689456	60689537	60678226	60678285	60690141	60690185	-0.08900	0.00000	0.00030	2included	K562	HNRNPU
MXE	ANXA2	ENSG00000182718.12	chr15	-	60653139	60653253	60656627	60656722	60649344	60649435	60678226	60678285	0.06100	0.00001	0.00048	1included	K562	SF3B4

Showing 1 to 10 of 32 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

ANXA2

General Information

Functions

Localization

Domains (AlphaFold: ANXA2)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for ANXA2 is not avaliable on ENCORE database.

30 proteins are bound to ANXA2 RNA:

eCLIP assay for ANXA2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for ANXA2 is not available on ENCORE database.

154 RBPs can affect the gene expression of ANXA2 :

The Knockdown/knockout RNA-Seq assay for ANXA2 is not available on ENCORE database.

18 RBPs can affect the splicing of ANXA2 :

The Knockdown/knockout RNA-Seq assay for ANXA2 is not avaliable on ENCORE database.