RPS10

General Information

Gene Name : RPS10
Gene ID : ENSG00000124614.15
Essential Gene : Yes

Functions

rRNA processing
Ribosome & basic translation
Translation regulation

Localization

Not Available

Domains (AlphaFold: RPS10)

No checked domain (RRM, ZNF, KH, Helicase, Nuclease, dRBM or PUM_HD)

Antibody Validation

MBLI: RN070PW

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	RPS10	ENSG00000124614.15	2206.56	2701.91	2454.23	ENCSR000AEF
HepG2	RPS10	ENSG00000124614.15	2949.80	2267.67	2608.74	ENCSR985KAT
K562	RPS10	ENSG00000124614.15	3433.60	3506.46	3470.03	ENCSR000AEO

Assays

3 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
eCLIP	eCLIP: 4104	ENCSR937RSF	RPS10	K562	Released	ENCAB391UDZ	ENCSR701KRV
knockdown followed by RNA-seq	RPS10-BGKLV13-K562	ENCSR004RGI	RPS10	K562	Released		ENCSR084SCN	shRNA	KD% = 33.7,36.3
knockdown followed by RNA-seq	RPS10-BGHLV14-HepG2	ENCSR410UHJ	RPS10	HepG2	Released		ENCSR491FOC	shRNA	KD% = 50.1,49.7

eCLIP

RBP	Exp_UID	Cell_Line	ENCODE_ACCESSION	Control_ENCODE_ACCESSION	ENCODE_Antibody_ID	Antibody	Lot_num	Status	Project
RPS10	4104	K562	ENCSR937RSF	ENCSR701KRV	ENCAB391UDZ	RN070PW	001	Released	ENCODE4

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
RPS10	ENCAB391UDZ	RN070PW	1			Released, ENCODE4	BGHLV14-41, Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
RPS10	K562	shRNA			BGKLV11-47,BGKLV11-48	BGKLV11-1,BGKLV11-2	NO AB,NO AB	NotSatisfied	ENCODE3
RPS10	K562	shRNA	ENCSR004RGI	ENCSR084SCN	RPS10_BGKLV13_63,RPS10_BGKLV13_64	non-target_BGKLV13_73,non-target_BGKLV13_74	33.7,36.3	Released	ENCODE3
RPS10	HepG2	shRNA	ENCSR410UHJ	ENCSR491FOC	RPS10_BGHLV14-41,RPS10_BGHLV14-42	NT_BGHLV14-1,NT_BGHLV14-2	50.1,49.7	Released	ENCODE3

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
RPS10	Product_ID: RN070PW Lot_ID: 1 Source: MBLI Target Name: RPS10-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for RPS10 is not avaliable on ENCORE database.

Proteins bound to RNA

RPS10 RNA is bound by 26 proteins.

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eCLIP assay for RPS10 is not avaliable on ENCORE database.

26 proteins are bound to RPS10 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr6	34393807	34393843	-	5'-UTR,intron-Distal,intron-Proximal	4.71790	400.00000	K562	PABPC4
chr6	34392482	34392508	-	CDS,intron-Distal	3.34766	400.00000	K562	YBX3
chr6	34392606	34392614	-	CDS,intron-Distal	3.08339	400.00000	K562	YBX3
chr6	34392848	34392850	-	CDS,intron-Distal,intron-Proximal	3.05945	400.00000	K562	YBX3
chr6	34392614	34392617	-	CDS,intron-Distal	3.09542	400.00000	K562	YBX3
chr6	34392850	34392853	-	CDS,intron-Distal	3.06361	400.00000	K562	YBX3
chr6	34392853	34392865	-	CDS,intron-Distal	3.02217	400.00000	K562	YBX3
chr6	34392479	34392482	-	CDS,intron-Distal	3.45975	400.00000	K562	YBX3
chr6	34392509	34392528	-	CDS,intron-Distal	3.09105	400.00000	K562	YBX3
chr6	34392602	34392606	-	CDS,intron-Distal	3.08469	86.10484	K562	YBX3
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 92 entries

eCLIP assay for RPS10 is not avaliable on ENCORE database.

Diffrential Expression

3,975 differentially expressed genes after Knockdown/Knockout RPS10 protein.

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128 RBPs can affect the levels of RPS10.

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3,975 differentially expressed genes after Knockdown/Knockout RPS10 protein :

Only display 100 entries as example. Please click "View All" button to see all 3,975 entries.

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Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
ANLN	ENSG00000011426.6	614.08530	2263.45740	-1.88200	30.82810	27.96490	HepG2	RPS10
BRCA1	ENSG00000012048.15	247.35870	973.54290	-1.97660	27.76910	25.08200	HepG2	RPS10
CROT	ENSG00000005469.7	738.31570	199.99610	1.88420	23.65700	21.16830	HepG2	RPS10
CYP24A1	ENSG00000019186.5	69.39510	327.62940	-2.23920	19.97380	17.70580	HepG2	RPS10
MGST1	ENSG00000008394.8	685.89550	1873.55120	-1.44970	18.94810	16.74110	HepG2	RPS10
POLA2	ENSG00000014138.4	100.87680	356.40890	-1.82090	16.14760	14.09100	HepG2	RPS10
CX3CL1	ENSG00000006210.6	4130.55310	1707.73270	1.27420	16.07060	14.02030	HepG2	RPS10
DEPDC1	ENSG00000024526.12	148.04950	470.97090	-1.66960	15.88960	13.84960	HepG2	RPS10
PLEKHB1	ENSG00000021300.9	635.53920	1560.88550	-1.29630	15.02020	13.03030	HepG2	RPS10
C1orf112	ENSG00000000460.12	117.41520	378.86880	-1.69010	14.80710	12.82970	HepG2	RPS10
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 100 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

128 RBPs can affect the gene expression of RPS10 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
RPS10	ENSG00000124614.9	8741.75870	24704.90870	-1.49880	171.13540	168.92780	HepG2	SRSF1
RPS10	ENSG00000124614.9	7449.89480	22734.05660	-1.60960	156.29710	153.79070	HepG2	PTBP1
RPS10	ENSG00000124614.9	9213.81810	25300.46200	-1.45730	137.58980	135.30740	HepG2	NELFE
RPS10	ENSG00000124614.9	3674.64870	11818.86220	-1.68540	110.65760	106.29590	K562	RPS10
RPS10	ENSG00000124614.9	9174.74480	24620.62070	-1.42410	87.65700	85.01010	HepG2	QKI
RPS10	ENSG00000124614.9	12029.91120	23564.59530	-0.97000	65.51900	63.37350	HepG2	RECQL
RPS10	ENSG00000124614.9	8944.88770	22345.14490	-1.32080	55.78310	53.09790	HepG2	RBM25
RPS10	ENSG00000124614.9	12778.15900	23668.30990	-0.88930	55.02080	53.05730	HepG2	SF3B4
RPS10	ENSG00000124614.9	1675.76840	9690.59790	-2.53180	46.98910	43.57500	HepG2	RPS10
RPS10	ENSG00000124614.9	8826.27880	25548.39770	-1.53340	45.03800	42.68070	HepG2	MAGOH
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 146 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for RPS10 is not available on ENCORE database.

1 RBPs can affect the splicing of RPS10 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
A3SS	RPS10	ENSG00000124614.9	chr6	-	34392445	34392678			34392445	34392617	34392848	34392998	0.05700	0.00000	0.00000	longer	K562	AQR
A3SS	RPS10	ENSG00000124614.9	chr6	-	34389506	34389603			34389506	34389584	34392445	34392657	0.05400	0.00000	0.00000	longer	K562	AQR
A3SS	RPS10	ENSG00000124614.9	chr6	-	34392848	34393030			34392848	34392998	34393572	34393803	0.46500	0.00000	0.00000	longer	K562	AQR
A3SS	RPS10	ENSG00000124614.9	chr6	-	34389506	34389729			34389506	34389603	34392445	34392657	-0.85900	0.00000	0.00000	shorter	K562	AQR
MXE	RPS10	ENSG00000124614.9	chr6	-	34386145	34386201	34389506	34389603	34385230	34385324	34392445	34392617	0.11000	0.00000	0.00000	1included	K562	AQR
A3SS	RPS10	ENSG00000124614.9	chr6	-	34392848	34393071			34392848	34393030	34393808	34393902	-0.75500	0.00001	0.00012	shorter	K562	AQR
A3SS	RPS10	ENSG00000124614.9	chr6	-	34385230	34385447			34385230	34385324	34385574	34385731	0.38500	0.00002	0.00021	longer	K562	AQR
MXE	RPS10	ENSG00000124614.9	chr6	-	34386052	34386201	34389506	34389603	34385230	34385324	34392445	34392617	0.37000	0.00005	0.00062	1included	K562	AQR
SE	RPS10	ENSG00000124614.9	chr6	-	34389502	34389603			34386145	34386201	34392445	34392635	0.39500	0.00010	0.00169	included	K562	AQR
A3SS	RPS10	ENSG00000124614.9	chr6	-	34392544	34392755			34392544	34392635	34392848	34392998	-0.20300	0.00606	0.03423	shorter	K562	AQR

Showing 1 to 10 of 10 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

RPS10

General Information

Functions

Localization

Domains (AlphaFold: RPS10)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for RPS10 is not avaliable on ENCORE database.

26 proteins are bound to RPS10 RNA:

eCLIP assay for RPS10 is not avaliable on ENCORE database.

Diffrential Expression

3,975 differentially expressed genes after Knockdown/Knockout RPS10 protein :

128 RBPs can affect the gene expression of RPS10 :

The Knockdown/knockout RNA-Seq assay for RPS10 is not available on ENCORE database.

1 RBPs can affect the splicing of RPS10 :

The Knockdown/knockout RNA-Seq assay for RPS10 is not avaliable on ENCORE database.