YAF2

General Information

Gene Name       : YAF2
Gene ID             : ENSG00000015153.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: YAF2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878YAF2ENSG00000015153.1423.2018.0020.60ENCSR000AEF
HepG2YAF2ENSG00000015153.143.887.685.78ENCSR985KAT
K562YAF2ENSG00000015153.1413.8115.4114.61ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
YAF2Ribo-STAMP-293TshRNABGRSLV05-43,BGRSLV05-44BGRSLV05-1,BGRSLV05-2NotSatisfiedENCORE2
YAF2Ribo-STAMP-293TshRNAYAF2-BGRSLV08-5,YAF2-BGRSLV08-6NT-BGRSLV08-1,NT-BGRSLV08-2,SubmittedENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for YAF2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • YAF2 RNA is bound by 10 proteins.  







eCLIP assay for YAF2 is not avaliable on ENCORE database.





10 proteins are bound to YAF2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr124263191942632007-5'-UTR,CDS,intron-Distal,intron-Proximal3.430963.32039HepG2PPIG
chr124263139542631522-5'-UTR,CDS,intron-Distal,intron-Proximal4.033764.28220HepG2GRWD1
chr124263190042631959-5'-UTR,CDS,intron-Distal3.565704.88100K562AQR
chr124260088842600990-intron-Distal4.178653.87294K562TARDBP
chr124261329642613440-intron-Distal5.5066712.37862K562TARDBP
chr124258958642589644-intron-Distal3.058033.35050HepG2SUGP2
chr124258358342583663-intron-Distal5.0115810.34143K562QKI
chr124260273742602841-intron-Distal3.149293.07751K562KHSRP
chr124262401942624062-intron-Distal7.0161026.23281K562PTBP1
chr124261585142615999-intron-Distal5.7844516.54184K562KHSRP
chr124260406942604117-intron-Distal,intron-Proximal4.174113.77802HepG2U2AF2
chr124260749642607569-intron-Distal4.805268.24653K562KHSRP
chr124260743442607496-intron-Distal4.173744.72162K562KHSRP
chr124261686642616932-intron-Distal3.736863.06194K562ILF3
chr124260450042604623-intron-Distal,intron-Proximal3.522894.96160K562KHSRP
chr124262402042624091-intron-Distal4.6258210.55454HepG2PTBP1
chr124261195142612016-intron-Distal3.540895.39069K562TARDBP
chr124260288742603000-intron-Distal4.122908.11138K562KHSRP
chr124258358042583655-intron-Distal4.967694.51735HepG2QKI
chr124261457442614649-intron-Distal4.974577.44287K562TARDBP
chr124260758242607679-intron-Distal4.377825.41654K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for YAF2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for YAF2 is not available on ENCORE database.

  • 37 RBPs can affect the levels of YAF2.  








The Knockdown/knockout RNA-Seq assay for YAF2 is not available on ENCORE database.





37 RBPs can affect the gene expression of YAF2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
YAF2ENSG00000015153.10145.19680232.22070-0.677504.311803.41970HepG2DAZAP1
YAF2ENSG00000015153.10106.33160172.68760-0.699602.538401.97040HepG2EIF2S1
YAF2ENSG00000015153.10279.49120185.799300.589002.208701.59120HepG2EIF4B
YAF2ENSG00000015153.10153.88210211.54500-0.459102.163501.55740HepG2HNRNPL
YAF2ENSG00000015153.10244.59670177.990000.458502.174101.62550HepG2PCBP1
YAF2ENSG00000015153.10205.69840119.233500.786603.317502.44060HepG2PRPF8
YAF2ENSG00000015153.10318.93670148.123901.106405.523104.54750HepG2RAVER1
YAF2ENSG00000015153.10294.11910178.018200.724304.391403.55810HepG2RBM25
YAF2ENSG00000015153.1084.27430140.26030-0.734903.017202.35020HepG2SAFB2
YAF2ENSG00000015153.10260.63530188.566200.466902.103001.57630HepG2SF3B4
YAF2ENSG00000015153.10139.82070210.73420-0.591803.075202.34070HepG2SLBP
YAF2ENSG00000015153.10352.66950196.816700.841406.788406.12760HepG2SRSF1
YAF2ENSG00000015153.10152.16950236.29560-0.634903.525602.96290HepG2SSB
YAF2ENSG00000015153.10245.20090176.890900.471002.166901.65980HepG2TAF15
YAF2ENSG00000015153.10103.96190154.40030-0.570602.299501.77580HepG2TRIM56
YAF2ENSG00000015153.10278.72260176.221100.661303.275302.59700HepG2U2AF1
YAF2ENSG00000015153.1090.57410151.46630-0.741802.406901.72650HepG2XRN2
YAF2ENSG00000015153.10346.05160245.571000.494702.604301.46490K562AARS
YAF2ENSG00000015153.10566.50890341.202300.731408.096407.19590K562AGGF1
YAF2ENSG00000015153.10576.74800355.028900.699906.107605.11180K562AKAP8L
YAF2ENSG00000015153.10491.74130372.496600.400602.598201.71550K562ATP5C1
YAF2ENSG00000015153.10203.12180373.65930-0.879407.417106.12690K562CPSF6
YAF2ENSG00000015153.10602.02230498.420500.272401.869701.31450K562DDX47
YAF2ENSG00000015153.10527.19360382.083800.464303.597602.58160K562DKC1
YAF2ENSG00000015153.10445.40170604.50330-0.440603.114902.12020K562EIF4G2
YAF2ENSG00000015153.10265.82630356.76600-0.424502.113201.41570K562GPKOW
YAF2ENSG00000015153.10612.84260335.649500.868503.835802.32000K562HNRNPA2B1
YAF2ENSG00000015153.10319.38590450.47890-0.496202.960001.86310K562HNRNPL
YAF2ENSG00000015153.10612.47160376.800800.700702.647101.84180K562KIF1C
YAF2ENSG00000015153.10247.94540348.23780-0.490102.716601.84980K562METAP2
YAF2ENSG00000015153.10613.63960295.865101.052408.774306.85670K562NAA15
YAF2ENSG00000015153.10481.85630293.499100.715102.555201.61400K562PABPN1
YAF2ENSG00000015153.10474.19700312.787900.600204.267403.04720K562PCBP2
YAF2ENSG00000015153.10326.69740208.134100.650303.486102.64300K562PRPF8
YAF2ENSG00000015153.101125.06620352.145201.6757034.2768032.32200K562PUS1
YAF2ENSG00000015153.10656.39350343.067800.9360012.6567011.39020K562RBM15
YAF2ENSG00000015153.10306.44270212.019300.531302.376101.62100K562RPS19
YAF2ENSG00000015153.10267.85890372.65050-0.476303.167302.29530K562SF3A3
YAF2ENSG00000015153.10456.84300334.938700.447702.798202.08870K562SRSF1
YAF2ENSG00000015153.10293.66750400.39930-0.447303.031802.28040K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for YAF2 is not available on ENCORE database.





4 RBPs can affect the splicing of YAF2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEYAF2ENSG00000015153.10chr12-425929374259303742555414425555674263140042631526-0.093000.003230.05359excludedK562SRSF1
SEYAF2ENSG00000015153.10chr12-4262941542629557425554144255556742631400426315260.371000.000000.00000includedK562AQR
SEYAF2ENSG00000015153.10chr12-4259293742593037425554144255556742631400426315260.463000.001660.03010includedK562U2AF2
A3SSYAF2ENSG00000015153.10chr12-4255541442555637425554144255556742631400426315260.309000.000000.00000longerK562AQR
MXEYAF2ENSG00000015153.10chr12-42592937425930374262941542629557425554144255556742631400426315260.363000.011270.069731includedK562AQR
MXEYAF2ENSG00000015153.10chr12-42592937425930374262941542629525425554144255556742631400426315260.456000.006600.045241includedK562AQR
MXEYAF2ENSG00000015153.10chr12-4260434942604421426294154262955742555414425555674263140042631526-0.814000.000400.029882includedHepG2AKAP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for YAF2 is not avaliable on ENCORE database.