USP45

General Information

Gene Name       : USP45
Gene ID             : ENSG00000123552.17
Essential Gene : No

Functions

Localization

Domains (AlphaFold: USP45)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878USP45ENSG00000123552.1715.3411.8613.60ENCSR000AEF
HepG2USP45ENSG00000123552.174.888.336.61ENCSR985KAT
K562USP45ENSG00000123552.1718.1221.4819.80ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for USP45 is not avaliable on ENCORE database.



Proteins bound to RNA
  • USP45 RNA is bound by 7 proteins.  







eCLIP assay for USP45 is not avaliable on ENCORE database.





7 proteins are bound to USP45 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr69991602199916129-3'-UTR,CDS,intron-Distal,intron-Proximal3.9379411.75440K562KHSRP
chr69995535299955408-5'-UTR,CDS,intron-Distal,intron-Proximal4.466164.84481HepG2PPIG
chr69995530399955332-5'-UTR,CDS,intron-Distal,intron-Proximal4.054103.38968HepG2BCLAF1
chr69995163199951698-5'-UTR,CDS,intron-Distal,intron-Proximal3.754074.76554HepG2BCLAF1
chr69992400899924105-5'-UTR,CDS,intron-Distal,intron-Proximal3.750035.57819K562UCHL5
chr69995648299956564-5'-UTR,CDS,intron-Distal,intron-Proximal3.998598.94445HepG2BCLAF1
chr69995169899951743-5'-UTR,CDS,intron-Distal,intron-Proximal3.826265.35703HepG2BCLAF1
chr69993613499936176-5'-UTR,CDS,intron-Distal,intron-Proximal3.127683.39477K562BUD13
chr69993654799936620-5'-UTR,CDS,intron-Distal,intron-Proximal3.891895.36555HepG2BCLAF1
chr69995648399956582-5'-UTR,CDS,intron-Distal,intron-Proximal4.835935.18660HepG2PPIG
chr69995794299958012-5'-UTR,CDS,intron-Distal,intron-Proximal3.474714.06013K562PRPF8
chr69993662099936695-5'-UTR,CDS,intron-Distal4.791076.04243HepG2BCLAF1
chr69991641899916473-CDS,intron-Distal4.054103.38968HepG2BCLAF1
chr69993621399936280-intron-Distal,intron-Proximal3.934835.98773K562KHSRP
chr69991625999916348-intron-Distal,intron-Proximal4.459325.68841K562KHSRP
chr69991466599914715-intron-Distal,intron-Proximal3.996863.90026K562KHSRP
chr69993342899933514-intron-Distal4.002323.50357HepG2QKI
chr69993638599936438-intron-Distal3.162203.48890K562KHSRP
chr69991626899916356-intron-Distal,intron-Proximal3.458623.88924K562PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for USP45 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for USP45 is not available on ENCORE database.

  • 62 RBPs can affect the levels of USP45.  








The Knockdown/knockout RNA-Seq assay for USP45 is not available on ENCORE database.





62 RBPs can affect the gene expression of USP45 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
USP45ENSG00000123552.13441.85180279.252800.661906.580405.72430HepG2ACO1
USP45ENSG00000123552.13180.00630306.36970-0.767204.283703.44550HepG2CPSF6
USP45ENSG00000123552.13323.07920428.76970-0.408303.080602.30480HepG2DAZAP1
USP45ENSG00000123552.13412.91010240.115500.782005.235404.39840HepG2DDX3X
USP45ENSG00000123552.13142.47210256.63920-0.849104.693103.87950HepG2DNAJC2
USP45ENSG00000123552.13454.68600213.332601.091707.679906.56380HepG2EIF4B
USP45ENSG00000123552.13293.09610405.18160-0.467202.641701.84390HepG2EIF4G2
USP45ENSG00000123552.13293.32230205.091100.516102.318801.70740HepG2G3BP1
USP45ENSG00000123552.13341.87870217.679200.651203.663102.63100HepG2G3BP2
USP45ENSG00000123552.13227.70210347.31010-0.609103.042602.37540HepG2GPKOW
USP45ENSG00000123552.13199.33180290.72110-0.544502.067001.45710HepG2HNRNPC
USP45ENSG00000123552.13237.24680329.84420-0.475403.092202.33680HepG2HNRNPF
USP45ENSG00000123552.13308.75770207.581700.572702.815002.11030HepG2HNRNPK
USP45ENSG00000123552.13179.97910390.59110-1.1178013.8822012.48140HepG2HNRNPL
USP45ENSG00000123552.13180.09110288.79760-0.681303.330702.67070HepG2HNRNPU
USP45ENSG00000123552.13209.19130324.80040-0.634704.306303.41980HepG2IGF2BP1
USP45ENSG00000123552.13392.18540209.673700.903305.736004.24060HepG2KHSRP
USP45ENSG00000123552.13321.42990221.122000.539602.552901.92120HepG2MAGOH
USP45ENSG00000123552.13332.51900222.371800.580402.035801.48960HepG2MATR3
USP45ENSG00000123552.13300.43170202.510700.568903.455902.79420HepG2PCBP1
USP45ENSG00000123552.13292.68380405.84320-0.471602.829102.22680HepG2PUF60
USP45ENSG00000123552.13162.55940284.43760-0.807106.401405.53380HepG2PUS1
USP45ENSG00000123552.13309.41480223.190400.471202.235401.66370HepG2QKI
USP45ENSG00000123552.13632.14690470.460700.426103.277502.72660HepG2RBM22
USP45ENSG00000123552.13324.92000202.544300.681704.174703.36170HepG2RBM25
USP45ENSG00000123552.13403.51590229.322100.815206.888906.10300HepG2NELFE
USP45ENSG00000123552.13319.81260213.553600.582503.481502.79980HepG2RECQL
USP45ENSG00000123552.13239.00830355.35270-0.572203.431602.68340HepG2RPLP0
USP45ENSG00000123552.13191.69150257.17590-0.424001.954101.39680HepG2SAFB2
USP45ENSG00000123552.13292.12370214.551700.445202.075001.55170HepG2SF3B4
USP45ENSG00000123552.13748.22870531.367400.493705.470404.83140HepG2SRFBP1
USP45ENSG00000123552.13499.52140223.931601.1574014.9787014.06660HepG2SRSF1
USP45ENSG00000123552.13518.61830352.980500.555002.898001.86910HepG2SRSF3
USP45ENSG00000123552.13213.38670324.06790-0.602804.352103.51000HepG2SRSF7
USP45ENSG00000123552.13347.43310182.168200.931409.276308.37050HepG2SRSF9
USP45ENSG00000123552.13369.60870461.35140-0.319902.005201.55070HepG2SSB
USP45ENSG00000123552.13460.98650201.239701.1957011.0396010.03760HepG2TAF15
USP45ENSG00000123552.13226.36900323.01150-0.512902.479301.78710HepG2TARDBP
USP45ENSG00000123552.13330.34590184.953000.836706.470405.19710HepG2TIA1
USP45ENSG00000123552.13152.29820280.54980-0.881404.401703.80110HepG2TIAL1
USP45ENSG00000123552.13191.41520283.13400-0.564802.259501.73950HepG2TRIM56
USP45ENSG00000123552.13436.04140275.095400.664404.278603.50660HepG2U2AF1
USP45ENSG00000123552.13216.42050154.527600.485902.117801.45470HepG2UCHL5
USP45ENSG00000123552.13363.68800266.037600.451002.743902.14920HepG2UTP3
USP45ENSG00000123552.13437.02890253.640600.784803.747802.26170HepG2XRCC5
USP45ENSG00000123552.13171.15390257.47560-0.589102.061301.42710HepG2XRN2
USP45ENSG00000123552.13439.20580303.058000.535204.854304.18170HepG2ZNF622
USP45ENSG00000123552.13689.63310858.57870-0.316102.447201.90800K562AGGF1
USP45ENSG00000123552.13707.67200893.39980-0.336202.145001.56700K562AKAP8L
USP45ENSG00000123552.13840.709901129.41550-0.425903.525702.87920K562AQR
USP45ENSG00000123552.131883.188801557.934000.273402.421201.51060K562CELF1
USP45ENSG00000123552.13311.16050507.66450-0.706205.272703.98870K562EFTUD2
USP45ENSG00000123552.13542.45190671.67490-0.308302.475501.34480K562EIF2S1
USP45ENSG00000123552.13497.90970670.16910-0.428603.108202.35310K562EIF2S2
USP45ENSG00000123552.13471.18100659.52650-0.485103.602202.62400K562FIP1L1
USP45ENSG00000123552.13513.37670664.40230-0.372002.986602.36170K562FXR1
USP45ENSG00000123552.131108.05870703.902400.654505.048904.02870K562G3BP2
USP45ENSG00000123552.13633.67030770.68680-0.282402.100201.32360K562HNRNPU
USP45ENSG00000123552.13597.90100793.93920-0.409102.241601.34640K562IGF2BP2
USP45ENSG00000123552.13647.16220833.22310-0.364602.153701.35010K562MATR3
USP45ENSG00000123552.13461.84450774.78840-0.746403.297002.18810K562PABPN1
USP45ENSG00000123552.13294.01060494.01310-0.748705.376304.32780K562PRPF8
USP45ENSG00000123552.13528.93530811.07400-0.616705.021904.15060K562PTBP1
USP45ENSG00000123552.131038.796401382.37200-0.412203.342402.44620K562PUF60
USP45ENSG00000123552.13693.91990885.93770-0.352402.041901.56200K562PUS1
USP45ENSG00000123552.13568.08970777.96860-0.453602.795701.95100K562RBM22
USP45ENSG00000123552.13516.14610732.17690-0.504404.791103.65330K562SF3B4
USP45ENSG00000123552.13523.40570864.05970-0.723202.995801.61530K562SFPQ
USP45ENSG00000123552.13269.02360378.38070-0.492102.566101.58950K562SRFBP1
USP45ENSG00000123552.131026.00220795.072400.367802.519001.83950K562SRSF1
USP45ENSG00000123552.131044.35920791.456500.399902.698501.46810K562STAU1
USP45ENSG00000123552.13470.09800804.77390-0.775606.038504.96470K562TARDBP
USP45ENSG00000123552.13557.80820776.26670-0.476803.372302.45610K562TIA1
USP45ENSG00000123552.13323.92210447.02990-0.464702.637001.71850K562TRIM56
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for USP45 is not available on ENCORE database.





4 RBPs can affect the splicing of USP45 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEUSP45ENSG00000123552.13chr6-9991597599916046999145479991463999916412999164940.647000.000000.00001includedK562SRSF1
SEUSP45ENSG00000123552.13chr6-9992764199927778999240189992410699930628999307590.204000.000440.06531includedK562LARP4
SEUSP45ENSG00000123552.13chr6-999276419992777899924018999241069993062899930759-0.153000.001020.04083excludedK562PTBP1
A3SSUSP45ENSG00000123552.13chr6-9993062899930779999306289993075999936075999361940.063000.000120.00100longerK562AQR
A3SSUSP45ENSG00000123552.13chr6-9993655699936718999365569993669699951640999517410.155000.000000.00000longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for USP45 is not avaliable on ENCORE database.