SIAH1

General Information

Gene Name       : SIAH1
Gene ID             : ENSG00000196470.11
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: SIAH1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SIAH1ENSG00000196470.119.888.649.26ENCSR000AEF
HepG2SIAH1ENSG00000196470.1112.1519.3915.77ENCSR985KAT
K562SIAH1ENSG00000196470.119.778.799.28ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SIAH1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SIAH1 RNA is bound by 20 proteins.  







eCLIP assay for SIAH1 is not avaliable on ENCORE database.





20 proteins are bound to SIAH1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr164839600248396062-3'-UTR,CDS,intron-Distal,intron-Proximal5.8247221.42262K562PUM2
chr164839508748395205-3'-UTR,intron-Distal4.8082215.23822K562TARDBP
chr164839434148394443-3'-UTR,intron-Distal,intron-Proximal,polyA_site4.471295.45333HepG2CSTF2
chr164839486648394950-3'-UTR,intron-Distal4.055565.05351HepG2FUBP3
chr164839524048395282-3'-UTR,intron-Distal6.0905315.61756K562PUM2
chr164839505848395211-3'-UTR,intron-Distal4.4622814.44521HepG2FUBP3
chr164839954448399632-5'-UTR,intron-Distal5.5249610.99895HepG2HNRNPM
chr164841920748419297-5'-UTR,intron-Distal3.235093.14078HepG2GRSF1
chr164841911548419256-5'-UTR,intron-Distal3.763676.59200K562DDX3X
chr164841917448419327-5'-UTR,intron-Distal4.5892320.62481HepG2DDX3X
chr164841910948419174-5'-UTR,intron-Distal4.294527.77439HepG2DDX3X
chr164841905548419143-5'-UTR,intron-Distal3.487314.82023K562AATF
chr164841906248419201-5'-UTR,intron-Distal3.585334.27210HepG2NCBP2
chr164839931948399470-5'-UTR,CDS,intron-Distal5.0218116.19113HepG2HNRNPM
chr164841911548419177-5'-UTR,intron-Distal4.048585.09764HepG2NKRF
chr164839554948395590-CDS,intron-Distal4.325373.81597K562RBM15
chr164841331248413362-intron-Distal3.384073.84025HepG2SUGP2
chr164841769148417780-intron-Distal5.189937.87558HepG2HNRNPM
chr164841328548413410-intron-Distal3.502034.73075K562MATR3
chr164839992448399981-intron-Distal4.030193.82910K562NONO
chr164841799548418053-intron-Distal5.482418.95887HepG2HNRNPM
chr164840810048408275-intron-Distal3.708614.42611HepG2SFPQ
chr164841608048416132-intron-Distal3.890983.80060HepG2HNRNPC
chr164841809948418155-intron-Distal4.243038.19743HepG2HNRNPM
chr164841757348417624-intron-Distal4.219743.29197K562HNRNPM
chr164839920748399247-intron-Distal4.397455.02084HepG2HNRNPM
chr164840008648400135-intron-Distal4.229264.33692K562NONO
chr164839183948391943-intron-Distal3.884407.37475HepG2U2AF2
chr164841757548417631-intron-Distal5.097898.59719HepG2HNRNPM
chr164839869748398854-intron-Distal,intron-Proximal3.167765.85121K562KHSRP
chr164841898048419047-intron-Distal3.032484.17158HepG2NKRF
chr164841903348419103-intron-Distal3.187193.10641K562HNRNPM
chr164839981948399876-intron-Distal,intron-Proximal4.228154.23759K562NONO
chr164841821648418331-intron-Distal4.925898.51597K562NONO
chr164841873848418885-intron-Distal4.589554.76031HepG2XRN2
chr164841563448415776-intron-Distal3.750586.39350HepG2HNRNPL
chr164841855948418711-intron-Distal4.774849.70521HepG2NKRF
chr164840966848409725-intron-Distal4.302737.68255HepG2HNRNPL
chr164841799148418046-intron-Distal4.762854.28571K562HNRNPM
chr164839988848399999-intron-Distal,intron-Proximal3.141773.59357HepG2NKRF
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SIAH1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SIAH1 is not available on ENCORE database.

  • 43 RBPs can affect the levels of SIAH1.  








The Knockdown/knockout RNA-Seq assay for SIAH1 is not available on ENCORE database.





43 RBPs can affect the gene expression of SIAH1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SIAH1ENSG00000196470.7551.61050873.27180-0.662804.992004.30400HepG2AKAP1
SIAH1ENSG00000196470.7585.95000456.128800.361202.834002.05860HepG2AKAP8L
SIAH1ENSG00000196470.7468.76400743.78460-0.666009.279508.14450HepG2AUH
SIAH1ENSG00000196470.7216.21570401.58980-0.893307.476006.41760HepG2DDX21
SIAH1ENSG00000196470.7327.81250478.02050-0.544202.395701.67050HepG2DDX55
SIAH1ENSG00000196470.7507.09030321.376100.657902.920401.91720HepG2DDX59
SIAH1ENSG00000196470.7927.63620718.627600.368201.932801.40820HepG2DDX6
SIAH1ENSG00000196470.7542.29460434.354600.320102.107801.50420HepG2DKC1
SIAH1ENSG00000196470.71057.98380743.296900.509202.947202.23850HepG2EIF4B
SIAH1ENSG00000196470.71091.20060853.968900.353603.578702.90870HepG2ETF1
SIAH1ENSG00000196470.7573.14740443.634500.369402.372201.59980HepG2EWSR1
SIAH1ENSG00000196470.7449.94210714.51320-0.667205.266804.36200HepG2G3BP1
SIAH1ENSG00000196470.7460.83950306.151400.589903.627602.91670HepG2HNRNPLL
SIAH1ENSG00000196470.7545.65300774.85480-0.505903.204602.53010HepG2MATR3
SIAH1ENSG00000196470.7534.04750683.41310-0.355802.987802.36050HepG2PCBP1
SIAH1ENSG00000196470.7344.86330518.51740-0.588403.072801.98050HepG2PCBP2
SIAH1ENSG00000196470.7547.55290695.40740-0.344902.897802.34050HepG2PTBP1
SIAH1ENSG00000196470.7539.33460708.39800-0.393402.933002.24240HepG2PUM2
SIAH1ENSG00000196470.7984.64750713.759000.464105.012204.36690HepG2RBM22
SIAH1ENSG00000196470.7289.96210387.05390-0.416702.779602.13420HepG2SAFB2
SIAH1ENSG00000196470.7602.20060723.99270-0.265701.877601.37440HepG2SF3B4
SIAH1ENSG00000196470.7475.23350326.065700.543402.709701.71890HepG2SRSF3
SIAH1ENSG00000196470.7511.69030659.37850-0.365802.985202.33680HepG2SRSF5
SIAH1ENSG00000196470.7808.12210614.806400.394304.174203.52210HepG2SRSF9
SIAH1ENSG00000196470.7906.43580699.937200.372904.034203.44010HepG2SSB
SIAH1ENSG00000196470.7624.25800749.88560-0.264502.011601.46520HepG2SUCLG1
SIAH1ENSG00000196470.7195.90580422.30970-1.1081012.5181011.58660HepG2TIAL1
SIAH1ENSG00000196470.7267.18600426.09900-0.673306.650705.84340HepG2TRIM56
SIAH1ENSG00000196470.7689.96900363.883200.923009.079107.93290HepG2U2AF1
SIAH1ENSG00000196470.7650.65940382.803000.765207.846606.96020K562AGGF1
SIAH1ENSG00000196470.7554.75300420.615300.399202.438901.52610K562AKAP8
SIAH1ENSG00000196470.7695.46000398.317200.803908.652107.43070K562AKAP8L
SIAH1ENSG00000196470.7682.94580422.938900.691205.829405.03130K562AQR
SIAH1ENSG00000196470.7446.53620294.006200.602802.699202.00290K562G3BP2
SIAH1ENSG00000196470.7511.36870314.481300.701305.466504.36460K562HSPD1
SIAH1ENSG00000196470.7678.06120422.737700.681603.183402.29350K562KIF1C
SIAH1ENSG00000196470.7570.38480404.644800.495203.128501.96720K562MAK16
SIAH1ENSG00000196470.7605.24270473.569700.353802.071801.30160K562MBNL1
SIAH1ENSG00000196470.7713.18410331.936001.103305.406204.03130K562NAA15
SIAH1ENSG00000196470.7751.71650569.218800.401103.499802.29070K562PUM1
SIAH1ENSG00000196470.71280.48040395.069501.6964038.1116036.04360K562PUS1
SIAH1ENSG00000196470.7749.24230384.895800.9609012.6123011.34940K562RBM15
SIAH1ENSG00000196470.7183.01270282.29170-0.625202.646201.66840K562RPS3
SIAH1ENSG00000196470.7340.75610249.885000.447402.699601.77330K562SRPK2
SIAH1ENSG00000196470.7113.38030187.91040-0.728902.886001.92960K562TIAL1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SIAH1 is not available on ENCORE database.






No RBPs affect the alternative splcing events of SIAH1 on ENCORE database.





The Knockdown/knockout RNA-Seq assay for SIAH1 is not avaliable on ENCORE database.