RUFY1

General Information

Gene Name       : RUFY1
Gene ID             : ENSG00000176783.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: RUFY1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878RUFY1ENSG00000176783.1416.5415.5216.03ENCSR000AEF
HepG2RUFY1ENSG00000176783.1422.3618.7520.55ENCSR985KAT
K562RUFY1ENSG00000176783.1415.1815.3315.25ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for RUFY1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • RUFY1 RNA is bound by 17 proteins.  







eCLIP assay for RUFY1 is not avaliable on ENCORE database.





17 proteins are bound to RUFY1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr5179036709179036915+3'-UTR3.892014.41952K562IGF2BP1
chr5179032883179032971+3'-UTR,CDS,intron-Proximal4.446985.64484HepG2PRPF8
chr5179016623179016758+3'-UTR,CDS,intron-Distal,intron-Proximal4.200567.44508K562PRPF8
chr5179036320179036382+3'-UTR,CDS,intron-Proximal4.758455.13952K562SF3B4
chr5179020513179020609+3'-UTR,CDS3.112844.34383HepG2GRWD1
chr5179021922179021958+3'-UTR,CDS3.698833.12746HepG2GRWD1
chr5179023584179023649+3'-UTR,CDS4.149165.98894K562ZNF800
chr5179020474179020647+3'-UTR,CDS,intron-Proximal4.4210514.12560K562UCHL5
chr5179020536179020595+3'-UTR,CDS4.713115.44793K562ZNF622
chr5179025642179025719+3'-UTR,CDS,intron-Proximal4.332274.27476HepG2AQR
chr5179021868179021922+3'-UTR,CDS4.124044.23295HepG2GRWD1
chr5179032924179032940+3'-UTR,CDS,intron-Proximal4.442343.11721K562AQR
chr5179036382179036453+3'-UTR,CDS3.344334.45064HepG2GRWD1
chr5179036916179037005+3'-UTR3.547013.99870K562IGF2BP1
chr5179020497179020589+3'-UTR,CDS4.372827.82199HepG2BCLAF1
chr5179018629179018743+3'-UTR,CDS,intron-Proximal3.767148.44067K562UCHL5
chr5179023616179023681+3'-UTR,CDS3.713035.42720K562UCHL5
chr5179021961179022020+3'-UTR,CDS,intron-Proximal4.527314.13847K562AQR
chr5179023566179023616+3'-UTR,CDS3.400533.73423K562UCHL5
chr5178986789178986858+5'-UTR,intron-Distal,intron-Proximal5.262056.34931HepG2XPO5
chr5178977561178977722+5'-UTR,CDS3.495339.35854HepG2NCBP2
chr5179012802179012860+CDS4.173845.36555HepG2BCLAF1
chr5179016545179016587+CDS,intron-Distal,intron-Proximal3.728283.12746HepG2GRWD1
chr5178977606178977652+CDS6.019157.09207K562GEMIN5
chr5178977583178977655+CDS3.831163.25631HepG2PRPF4
chr5178994450178994509+CDS,intron-Proximal3.915933.18234K562BUD13
chr5178977682178977721+CDS3.313523.12941K562UCHL5
chr5179016546179016592+CDS,intron-Distal,intron-Proximal4.630113.89826HepG2BCLAF1
chr5179012801179012857+CDS3.054083.17744HepG2GRWD1
chr5178996339178996425+CDS3.570583.02345K562ZNF622
chr5179018192179018244+intron-Distal3.059503.45912HepG2HNRNPC
chr5179004651179004710+intron-Distal3.698813.14687K562CSTF2T
chr5178978030178978175+intron-Distal4.428424.48497K562NONO
chr5179032940179032969+intron-Proximal4.699633.62536K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for RUFY1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for RUFY1 is not available on ENCORE database.

  • 35 RBPs can affect the levels of RUFY1.  








The Knockdown/knockout RNA-Seq assay for RUFY1 is not available on ENCORE database.





35 RBPs can affect the gene expression of RUFY1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
RUFY1ENSG00000176783.10335.26770439.73130-0.391302.058601.46360HepG2DDX21
RUFY1ENSG00000176783.10570.76510466.109800.292101.879901.30500HepG2DKC1
RUFY1ENSG00000176783.10290.44530364.71410-0.328501.987501.41810HepG2DNAJC2
RUFY1ENSG00000176783.10331.74370511.43910-0.624504.015103.31030HepG2EIF2S1
RUFY1ENSG00000176783.10615.56220476.083000.370602.436601.65400HepG2EWSR1
RUFY1ENSG00000176783.10323.06030503.77130-0.641003.564602.29650HepG2FUS
RUFY1ENSG00000176783.10280.93590371.54680-0.403301.882101.33760HepG2HNRNPA1
RUFY1ENSG00000176783.10360.30960463.06530-0.362002.044801.34440HepG2MSI2
RUFY1ENSG00000176783.10284.05150437.00250-0.621502.689501.81620HepG2PABPC1
RUFY1ENSG00000176783.10439.65830540.11650-0.296901.796101.33630HepG2PTBP1
RUFY1ENSG00000176783.10683.14730559.862500.287002.136201.58520HepG2RECQL
RUFY1ENSG00000176783.10627.00470751.23930-0.260802.062301.60960HepG2SRFBP1
RUFY1ENSG00000176783.10416.27800522.60250-0.328202.366601.71930HepG2SRSF7
RUFY1ENSG00000176783.10771.54330652.241100.242201.795501.36060HepG2SSB
RUFY1ENSG00000176783.10503.61210398.975800.335901.973501.53640HepG2TIAL1
RUFY1ENSG00000176783.10700.46570489.491100.516903.258702.58160HepG2U2AF1
RUFY1ENSG00000176783.10471.48000366.963600.361502.596001.94230HepG2ZC3H8
RUFY1ENSG00000176783.10468.29850620.02170-0.404903.979503.35570HepG2ZNF622
RUFY1ENSG00000176783.10752.400101093.03500-0.538804.876504.13680K562AQR
RUFY1ENSG00000176783.10910.34330701.163600.376603.546102.50060K562ATP5C1
RUFY1ENSG00000176783.101015.30280753.509500.430103.436201.80130K562DDX19B
RUFY1ENSG00000176783.101231.610601015.442300.278302.905802.23810K562DDX47
RUFY1ENSG00000176783.10879.71060719.122100.290702.377701.57440K562DKC1
RUFY1ENSG00000176783.10679.77050817.87270-0.266801.929601.31040K562EIF2S2
RUFY1ENSG00000176783.10556.01210394.498400.495004.355703.36700K562EIF3G
RUFY1ENSG00000176783.10356.99450509.63380-0.513602.906901.44500K562GEMIN5
RUFY1ENSG00000176783.10632.25600812.91130-0.362602.778901.70350K562HNRNPA1
RUFY1ENSG00000176783.10737.52120900.22960-0.287602.208901.41200K562HNRNPU
RUFY1ENSG00000176783.10723.95080878.52520-0.279202.423501.66550K562MTPAP
RUFY1ENSG00000176783.10456.00650723.83090-0.666602.695301.72080K562PABPN1
RUFY1ENSG00000176783.10400.65740537.39860-0.423602.407801.57000K562PSIP1
RUFY1ENSG00000176783.10790.93710963.20040-0.284302.429401.66110K562SF3A3
RUFY1ENSG00000176783.10327.28220464.72890-0.505903.111002.00860K562SRFBP1
RUFY1ENSG00000176783.10722.11440986.82460-0.450605.951304.64400K562SRPK2
RUFY1ENSG00000176783.10855.09880595.107700.522805.071704.11850K562SRSF1
RUFY1ENSG00000176783.10416.74870602.33880-0.531403.897401.97580K562TBRG4
RUFY1ENSG00000176783.10403.84270549.04600-0.443102.646001.72570K562TRIM56
RUFY1ENSG00000176783.10375.25220578.49320-0.624405.957204.78150K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for RUFY1 is not available on ENCORE database.





14 RBPs can affect the splicing of RUFY1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SERUFY1ENSG00000176783.10chr5+179035285179035466179034582179034660179036376179036971-0.060000.003400.05572excludedK562SRSF1
SERUFY1ENSG00000176783.10chr5+1790352851790354661790345821790346601790363761790369710.128000.004070.08980includedK562AKAP8L
SERUFY1ENSG00000176783.10chr5+1790352851790354661790345821790346601790363761790369710.368000.000110.00450includedHepG2HNRNPK
SERUFY1ENSG00000176783.10chr5+1789903831789904761789895471789896651789944611789945630.051000.002250.02416includedK562AQR
SERUFY1ENSG00000176783.10chr5+1790352851790354661790345821790346601790363761790369710.096000.003120.04323includedK562PUS1
SERUFY1ENSG00000176783.10chr5+179007947179008013179004113179004137179012796179012866-0.279000.000050.00124excludedK562PUS1
SERUFY1ENSG00000176783.10chr5+179035285179035466179034582179034660179036376179036971-0.181000.000460.07861excludedK562GPKOW
SERUFY1ENSG00000176783.10chr5+1790133311790134761790127961790128661790165461790166480.093000.000040.02507includedK562BUD13
SERUFY1ENSG00000176783.10chr5+179035285179035466179034582179034660179036376179036971-0.054000.000130.03419excludedK562APOBEC3C
SERUFY1ENSG00000176783.10chr5+1790133311790134761790127961790128661790165461790166480.183000.000000.00176includedHepG2XPO5
SERUFY1ENSG00000176783.10chr5+179013331179013476179012796179012866179016546179016648-0.091000.000010.00052excludedHepG2SRSF1
SERUFY1ENSG00000176783.10chr5+179035285179035466179034582179034660179036376179036971-0.120000.000430.05314excludedHepG2SSB
SERUFY1ENSG00000176783.10chr5+1790352851790354661790345821790346601790363761790369710.089000.004930.09004includedK562RBM15
SERUFY1ENSG00000176783.10chr5+179007947179008013179004113179004137179012796179012866-0.316000.000010.00047excludedK562RBM15
SERUFY1ENSG00000176783.10chr5+179007947179008013179004075179004137179012796179012866-0.287000.000460.01488excludedK562AGGF1
SERUFY1ENSG00000176783.10chr5+179035285179035466179034563179034660179036376179036971-0.117000.000190.01032excludedHepG2HNRNPC
SERUFY1ENSG00000176783.10chr5+1789826501789827911789778381789778801789870251789871990.678000.000270.00642includedK562HNRNPC
SERUFY1ENSG00000176783.10chr5+179035285179035466179034582179034660179036376179036971-0.066000.001360.02484excludedK562HNRNPC
A3SSRUFY1ENSG00000176783.10chr5+1790079191790080131790079471790080131790040751790041370.078000.004520.02642longerK562AQR
MXERUFY1ENSG00000176783.10chr5+179004075179004137179007947179008013178996302178996426179012796179012866-0.237000.001070.066752includedK562SERBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for RUFY1 is not avaliable on ENCORE database.