RPAIN

General Information

Gene Name       : RPAIN
Gene ID             : ENSG00000129197.14
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: RPAIN)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878RPAINENSG00000129197.1431.7136.2633.98ENCSR000AEF
HepG2RPAINENSG00000129197.1435.4141.9738.69ENCSR985KAT
K562RPAINENSG00000129197.1421.5118.3419.93ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for RPAIN is not avaliable on ENCORE database.



Proteins bound to RNA
  • RPAIN RNA is bound by 16 proteins.  







eCLIP assay for RPAIN is not avaliable on ENCORE database.





16 proteins are bound to RPAIN RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1753359015335957+3'-UTR3.278323.12941K562UCHL5
chr1753314795331584+3'-UTR,CDS,intron-Distal,intron-Proximal3.232327.19667HepG2PRPF8
chr1753359075335985+3'-UTR5.6002958.04527K562PUM2
chr1753358995335971+3'-UTR3.393456.97264K562YBX3
chr1753358645335931+3'-UTR,CDS4.815057.35309K562LIN28B
chr1753314525331547+3'-UTR,CDS,intron-Distal,intron-Proximal3.075514.16939HepG2PPIG
chr1753358455335951+3'-UTR,CDS,intron-Proximal3.588684.51027K562BUD13
chr1753358015335901+3'-UTR,CDS,intron-Proximal4.059794.57435K562SF3B4
chr1753295615329632+3'-UTR,CDS,intron-Distal,intron-Proximal3.301054.49514HepG2XPO5
chr1753358495335943+3'-UTR,CDS,intron-Proximal3.352187.76412HepG2U2AF2
chr1753235045323561+5'-UTR,CDS3.558377.96348HepG2NCBP2
chr1753235055323612+5'-UTR,CDS,intron-Proximal3.8526710.83085K562DDX3X
chr1753235615323612+CDS,intron-Proximal3.264194.95054HepG2NCBP2
chr1753261345326198+CDS,intron-Proximal3.430985.46476K562AQR
chr1753247225324787+CDS,intron-Proximal3.173689.43433HepG2PPIG
chr1753261255326176+CDS,intron-Proximal5.5901212.18059HepG2PPIG
chr1753247665324787+CDS,intron-Proximal3.294175.12958K562UCHL5
chr1753246695324788+CDS,intron-Proximal3.197816.83963HepG2GRWD1
chr1753260885326125+CDS,intron-Proximal3.907777.91657HepG2PPIG
chr1753292615329387+CDS,intron-Distal,intron-Proximal3.083175.59833HepG2GRWD1
chr1753260975326127+CDS3.915017.03378HepG2GRWD1
chr1753246915324766+CDS3.612726.18248K562UCHL5
chr1753260865326168+CDS,intron-Proximal3.234877.58409K562UCHL5
chr1753236025323667+CDS,intron-Proximal4.153076.39176K562AQR
chr1753261315326211+CDS,intron-Proximal4.633949.10443HepG2PRPF8
chr1753261275326175+CDS,intron-Proximal3.593085.10069HepG2GRWD1
chr1753247265324789+CDS,intron-Proximal3.285035.00751HepG2BCLAF1
chr1753261905326290+intron-Distal,intron-Proximal3.710193.54718K562PRPF8
chr1753294155329477+intron-Distal,intron-Proximal4.491715.50278HepG2TIAL1
chr1753261575326207+intron-Proximal4.199874.11693K562BUD13
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for RPAIN is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for RPAIN is not available on ENCORE database.

  • 42 RBPs can affect the levels of RPAIN.  








The Knockdown/knockout RNA-Seq assay for RPAIN is not available on ENCORE database.





42 RBPs can affect the gene expression of RPAIN :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
RPAINENSG00000129197.101152.621701352.68050-0.230902.355001.71230HepG2AUH
RPAINENSG00000129197.101022.83210796.453100.360802.357501.49510HepG2BCCIP
RPAINENSG00000129197.10921.15410583.664300.658206.865205.97020HepG2BOP1
RPAINENSG00000129197.101017.69180805.476900.337303.773203.01900HepG2CKAP4
RPAINENSG00000129197.10896.56440745.109500.266902.580901.77310HepG2DDX19B
RPAINENSG00000129197.10569.95570747.97090-0.392102.227901.68990HepG2EIF2S1
RPAINENSG00000129197.101236.16590804.749200.619203.628302.84600HepG2EIF4B
RPAINENSG00000129197.101036.88800833.875800.314301.877201.30290HepG2FXR1
RPAINENSG00000129197.10805.70520635.246300.342802.262601.67360HepG2HNRNPA1
RPAINENSG00000129197.101028.46150783.151300.393002.854902.14490HepG2HNRNPK
RPAINENSG00000129197.10949.624901126.45230-0.246402.663102.00160HepG2HNRNPL
RPAINENSG00000129197.10884.92600701.940500.334103.275102.61920HepG2HNRNPU
RPAINENSG00000129197.101183.23820737.883600.681202.528801.59320HepG2IGF2BP3
RPAINENSG00000129197.10669.31650513.977400.380902.220601.54790HepG2NSUN2
RPAINENSG00000129197.10856.59780694.776300.302002.644601.81360HepG2PARN
RPAINENSG00000129197.10904.86220693.454900.383803.949203.25080HepG2PCBP1
RPAINENSG00000129197.10871.01290604.333200.527204.596003.58340HepG2PRPF8
RPAINENSG00000129197.10905.51850705.589900.359803.463202.86590HepG2PTBP1
RPAINENSG00000129197.10893.061101170.46700-0.390303.473202.81550HepG2PUF60
RPAINENSG00000129197.10991.494001241.58300-0.324502.997302.29880HepG2PUM2
RPAINENSG00000129197.10997.08690764.227600.383603.388902.70680HepG2QKI
RPAINENSG00000129197.101945.052101298.085100.5833010.726709.85260HepG2RBM22
RPAINENSG00000129197.101151.30830785.275800.551907.810106.98320HepG2NELFE
RPAINENSG00000129197.10999.67300731.337800.450805.261904.44610HepG2RECQL
RPAINENSG00000129197.10769.39090597.839400.363902.341801.61190HepG2RRP9
RPAINENSG00000129197.101522.35940793.411300.940109.280707.98800HepG2SF3A3
RPAINENSG00000129197.101100.25480734.657600.582608.614307.66060HepG2SF3B4
RPAINENSG00000129197.10908.526001122.23090-0.304803.655402.86760HepG2SLBP
RPAINENSG00000129197.101212.10590766.804100.6605011.6994010.87060HepG2SRSF1
RPAINENSG00000129197.10804.05020623.819300.366103.660603.04540HepG2SRSF9
RPAINENSG00000129197.101047.33840689.179700.603708.276907.39160HepG2TAF15
RPAINENSG00000129197.10813.81110633.319200.361702.770901.93470HepG2TIA1
RPAINENSG00000129197.10787.16470594.453800.405002.380701.79400HepG2U2AF1
RPAINENSG00000129197.101305.99440944.905400.466803.354102.74040K562AGGF1
RPAINENSG00000129197.101173.51100983.241500.255101.871301.32940K562AKAP8L
RPAINENSG00000129197.10838.632401129.13370-0.429102.587701.45920K562CCDC124
RPAINENSG00000129197.10370.78220497.14880-0.423102.572101.99390K562HNRNPC
RPAINENSG00000129197.101352.129901043.378600.373903.257202.35510K562KIF1C
RPAINENSG00000129197.10378.73690530.12950-0.485102.383701.68610K562PRPF8
RPAINENSG00000129197.10583.47490719.47600-0.302302.035901.44980K562PTBP1
RPAINENSG00000129197.101482.88670974.929600.604907.107906.28330K562PUS1
RPAINENSG00000129197.10451.75460776.95540-0.782302.475501.53400K562RPS3
RPAINENSG00000129197.10800.22240632.271900.339802.850202.02560K562SF3A3
RPAINENSG00000129197.10535.56200713.82970-0.414502.774402.06660K562TARDBP
RPAINENSG00000129197.10784.21900604.553200.375302.676501.84310K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for RPAIN is not available on ENCORE database.





43 RBPs can affect the splicing of RPAIN :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SERPAINENSG00000129197.10chr17+533139053315315329290532961953358615336196-0.231000.000020.00068excludedK562SRSF1
SERPAINENSG00000129197.10chr17+532929053315315326088532614953358615336024-0.357000.000000.00013excludedK562PRPF8
SERPAINENSG00000129197.10chr17+533139053315315329555532961953358615336196-0.349000.000580.01304excludedHepG2U2AF1
SERPAINENSG00000129197.10chr17+532929053315315326088532614953358615336024-0.309000.000010.00306excludedHepG2PRPF8
SERPAINENSG00000129197.10chr17+532955553296195326088532614953313905331973-0.178000.003890.08703excludedK562AKAP8L
SERPAINENSG00000129197.10chr17+532929053315315326088532614953358615336024-0.382000.000010.00152excludedK562XRCC6
SERPAINENSG00000129197.10chr17+533139053315315329290532961953358615336196-0.459000.000010.00020excludedHepG2U2AF2
SERPAINENSG00000129197.10chr17+533139053315315326088532614953358615336196-0.295000.000100.08203excludedHepG2LARP7
SERPAINENSG00000129197.10chr17+533139053315315329498532961953358615336196-0.156000.000180.02087excludedHepG2DDX3X
SERPAINENSG00000129197.10chr17+532929053315315326088532614953358615336024-0.342000.000000.00000excludedK562PUS1
SERPAINENSG00000129197.10chr17+533139053315315329290532940253358615336196-0.229000.000220.01835excludedHepG2NCBP2
SERPAINENSG00000129197.10chr17+532929053315315326088532614953358615336024-0.268000.000600.03491excludedK562EFTUD2
SERPAINENSG00000129197.10chr17+533139053315315326088532614953358615336196-0.229000.000820.03698excludedHepG2MATR3
SERPAINENSG00000129197.10chr17+533139053315315329555532961953358615336196-0.300000.000030.00120excludedK562U2AF1
SERPAINENSG00000129197.10chr17+532929053315315326088532614953358615336024-0.399000.000000.00001excludedHepG2PCBP2
SERPAINENSG00000129197.10chr17+533139053315315329555532961953358615336196-0.242000.002090.05436excludedHepG2SF3A3
SERPAINENSG00000129197.10chr17+532955553296195326088532614953313905331531-0.211000.000190.02075excludedK562HNRNPUL1
SERPAINENSG00000129197.10chr17+532929053294025326088532614953295555329619-0.209000.002220.08734excludedHepG2PCBP1
SERPAINENSG00000129197.10chr17+532929053315315326088532614953358615336024-0.279000.000190.01001excludedK562TARDBP
SERPAINENSG00000129197.10chr17+532929053315315326088532614953358615336024-0.454000.000000.00000excludedK562HNRNPU
SERPAINENSG00000129197.10chr17+532929053296195326088532614953313905331675-0.199000.005540.09863excludedK562RBM15
SERPAINENSG00000129197.10chr17+532929053315315326088532614953358615336024-0.222000.001480.03784excludedK562AGGF1
SERPAINENSG00000129197.10chr17+533139053315315329290532961953358615336196-0.223000.001670.06325excludedHepG2HNRNPU
SERPAINENSG00000129197.10chr17+532929053315315326088532614953358615336024-0.424000.000000.00000excludedHepG2XRCC6
SERPAINENSG00000129197.10chr17+5329290533153153260885326149533586153360240.200000.000330.02670includedHepG2SRSF9
SERPAINENSG00000129197.10chr17+5329456532961953260885326149533586153361960.508000.000380.06379includedK562EIF3G
RIRPAINENSG00000129197.10chr17+532929053296195329290532940253295555329619-0.224000.001460.07744excludedK562NONO
RIRPAINENSG00000129197.10chr17+5329290532961953292905329402532955553296190.284000.000880.00663includedK562PUS1
RIRPAINENSG00000129197.10chr17+5329290533153153292905329619533139053315310.316000.001350.01732includedHepG2SF3A3
RIRPAINENSG00000129197.10chr17+5329290533153153292905329619533139053315310.262000.001290.09018includedK562TAF15
RIRPAINENSG00000129197.10chr17+5329290533153153292905329619533139053315310.332000.001250.01083includedHepG2U2AF2
RIRPAINENSG00000129197.10chr17+5329290533153153292905329619533139053315310.196000.000000.00090includedK562NPM1
RIRPAINENSG00000129197.10chr17+5329290532961953292905329402532955553296190.250000.002600.03254includedHepG2PRPF8
RIRPAINENSG00000129197.10chr17+5329290533153153292905329619533139053315310.355000.000160.00335includedHepG2PRPF8
RIRPAINENSG00000129197.10chr17+5329290532961953292905329402532955553296190.462000.000290.02504includedHepG2HNRNPUL1
RIRPAINENSG00000129197.10chr17+5329290533153153292905329619533139053315310.210000.000010.00108includedK562HNRNPUL1
RIRPAINENSG00000129197.10chr17+5329290533153153292905329619533139053315310.328000.000000.00140includedHepG2EFTUD2
RIRPAINENSG00000129197.10chr17+5329290532961953292905329402532955553296190.335000.000500.04245includedK562PHF6
RIRPAINENSG00000129197.10chr17+5329290533153153292905329619533139053315310.167000.006770.06651includedK562AGGF1
RIRPAINENSG00000129197.10chr17+532929053315315329290532940253313905331531-0.102000.010780.09435excludedK562AGGF1
RIRPAINENSG00000129197.10chr17+5329290532961953292905329402532955553296190.201000.003020.05380includedHepG2IGF2BP3
RIRPAINENSG00000129197.10chr17+5329290533153153292905329619533139053315310.151000.000140.00522includedHepG2IGF2BP3
RIRPAINENSG00000129197.10chr17+5329290533153153292905329619533139053315310.134000.001280.04252includedHepG2MATR3
RIRPAINENSG00000129197.10chr17+5329290533153153292905329619533139053315310.104000.001630.02309includedHepG2PCBP1
RIRPAINENSG00000129197.10chr17+5329290533153153292905329619533139053315310.130000.000090.00368includedHepG2SRSF1
RIRPAINENSG00000129197.10chr17+5329290533153153292905329619533139053315310.168000.000000.00015includedHepG2QKI
RIRPAINENSG00000129197.10chr17+5329290532961953292905329402532955553296190.251000.000360.02446includedHepG2HNRNPA1
RIRPAINENSG00000129197.10chr17+5329290533153153292905329619533139053315310.262000.000070.00775includedHepG2HNRNPA1
RIRPAINENSG00000129197.10chr17+5329290532961953292905329402532955553296190.218000.004610.07600includedK562RBM22
RIRPAINENSG00000129197.10chr17+5329290533153153292905329619533139053315310.185000.001840.01883includedK562AKAP8L
RIRPAINENSG00000129197.10chr17+5329290532961953292905329402532955553296190.148000.002400.02463includedHepG2TAF15
RIRPAINENSG00000129197.10chr17+5329290533153153292905329619533139053315310.288000.000000.00000includedHepG2TAF15
RIRPAINENSG00000129197.10chr17+5329290533153153292905329619533139053315310.123000.001050.02086includedHepG2G3BP1
RIRPAINENSG00000129197.10chr17+532929053315315329290532961953313905331531-0.164000.001760.08856excludedK562EIF3G
RIRPAINENSG00000129197.10chr17+5329290532961953292905329402532955553296190.408000.000260.00515includedK562U2AF2
RIRPAINENSG00000129197.10chr17+5329290533153153292905329619533139053315310.234000.001470.02182includedK562U2AF2
RIRPAINENSG00000129197.10chr17+5329290533153153292905329619533139053315310.196000.002000.07385includedHepG2HNRNPC
RIRPAINENSG00000129197.10chr17+5329290533153153292905329619533139053315310.203000.001610.02975includedHepG2TIAL1
RIRPAINENSG00000129197.10chr17+5329290532961953292905329402532955553296190.295000.000000.00000includedHepG2NCBP2
RIRPAINENSG00000129197.10chr17+5329290533153153292905329619533139053315310.292000.000000.00000includedHepG2NCBP2
RIRPAINENSG00000129197.10chr17+5329290533153153292905329619533139053315310.345000.000000.00015includedHepG2HNRNPU
RIRPAINENSG00000129197.10chr17+5329290532961953292905329402532955553296190.216000.000030.00052includedHepG2SF3B4
RIRPAINENSG00000129197.10chr17+5329290533153153292905329619533139053315310.277000.000000.00000includedHepG2SF3B4
RIRPAINENSG00000129197.10chr17+5329290532961953292905329402532955553296190.274000.000020.00096includedHepG2FUBP3
RIRPAINENSG00000129197.10chr17+5329290533153153292905329619533139053315310.271000.000010.00029includedHepG2FUBP3
RIRPAINENSG00000129197.10chr17+5329290532961953292905329402532955553296190.229000.000000.00000includedHepG2RBM22
RIRPAINENSG00000129197.10chr17+5329290532961953292905329402532955553296190.205000.000060.00122includedHepG2HNRNPK
RIRPAINENSG00000129197.10chr17+5329290533153153292905329619533139053315310.231000.000000.00001includedHepG2HNRNPK
RIRPAINENSG00000129197.10chr17+5329290532961953292905329402532955553296190.200000.000090.00409includedHepG2PTBP1
RIRPAINENSG00000129197.10chr17+5329290533153153292905329619533139053315310.250000.000000.00000includedHepG2PTBP1
RIRPAINENSG00000129197.10chr17+5329290533153153292905329619533139053315310.309000.002660.02759includedK562EFTUD2
RIRPAINENSG00000129197.10chr17+5329290533153153292905329619533139053315310.210000.000010.00013includedK562AQR
RIRPAINENSG00000129197.10chr17+5329290533153153292905329619533139053315310.171000.001060.06646includedK562LARP4
RIRPAINENSG00000129197.10chr17+532929053296195329290532940253295555329619-0.349000.000220.00543excludedK562FXR1
MXERPAINENSG00000129197.10chr17+53295555329619533139053315315329290532940253358615336196-0.201000.007790.095312includedK562PUS1
MXERPAINENSG00000129197.10chr17+532955553296195331390533153153292905329402533586153361960.158000.005010.066091includedK562SRSF1
MXERPAINENSG00000129197.10chr17+532955553296195331390533153153260885326149533586153361960.263000.000010.000261includedK562SRSF1
MXERPAINENSG00000129197.10chr17+532929053296195331390533153153260885326149533586153361960.211000.000490.011101includedK562SRSF1
MXERPAINENSG00000129197.10chr17+532926553294025329555532961953260885326149533139053315310.059000.009100.058641includedK562AQR
MXERPAINENSG00000129197.10chr17+532926553294025329456532961953260885326149533139053315310.075000.008390.054921includedK562AQR
MXERPAINENSG00000129197.10chr17+532955553296195331390533153153292905329402533586153361960.301000.001610.051001includedHepG2SF3A3
MXERPAINENSG00000129197.10chr17+532955553296195331390533153153292905329402533586153361960.203000.000160.078251includedHepG2LIN28B
MXERPAINENSG00000129197.10chr17+532945653296195331390533153153260885326149533586153361960.183000.000050.057031includedHepG2LIN28B
MXERPAINENSG00000129197.10chr17+532949853296195331390533153153292905329402533586153361960.160000.000180.078251includedHepG2LIN28B
MXERPAINENSG00000129197.10chr17+53295555329619533139053315315326088532614953358615336196-0.155000.002550.060222includedHepG2XRN2
MXERPAINENSG00000129197.10chr17+532955553296195331390533153153260885326149533586153361960.397000.019390.090441includedHepG2U2AF2
MXERPAINENSG00000129197.10chr17+53295555329619533139053315315329290532940253358615336196-0.564000.000060.002232includedHepG2HNRNPUL1
MXERPAINENSG00000129197.10chr17+532929053294025329555532961953260885326149533139053315310.239000.004060.090511includedK562TAF15
MXERPAINENSG00000129197.10chr17+532929053294025329555532961953260885326149533139053315310.235000.002240.059261includedHepG2HNRNPU
MXERPAINENSG00000129197.10chr17+532929053293915329555532961953260885326149533139053315310.264000.000110.005601includedHepG2HNRNPU
MXERPAINENSG00000129197.10chr17+532929053296195331390533153153260885326149533586153361960.263000.000490.018121includedHepG2HNRNPU
MXERPAINENSG00000129197.10chr17+532955553296195331390533153153260885326149533586153361960.225000.000000.000281includedHepG2DDX3X
MXERPAINENSG00000129197.10chr17+532945653296195331390533153153260885326149533586153361960.171000.000030.002891includedHepG2DDX3X
MXERPAINENSG00000129197.10chr17+532949853296195331390533153153292905329402533586153361960.162000.000020.002301includedHepG2DDX3X
MXERPAINENSG00000129197.10chr17+532929053293915331390533153153260885326149533586153361960.170000.000340.022661includedHepG2DDX3X
MXERPAINENSG00000129197.10chr17+532929053296195331390533153153260885326149533586153361960.204000.000020.001921includedHepG2DDX3X
MXERPAINENSG00000129197.10chr17+532947753296195331390533153153292905329402533586153361960.165000.000020.001851includedHepG2DDX3X
MXERPAINENSG00000129197.10chr17+532955553296195331390533153153260885326149533586153361960.210000.001480.066711includedK562TIA1
MXERPAINENSG00000129197.10chr17+532949853296195331390533153153292905329402533586153361960.116000.001900.094501includedHepG2G3BP1
MXERPAINENSG00000129197.10chr17+532945653296195331390533153153260885326149533586153361960.213000.002350.056671includedHepG2TIAL1
MXERPAINENSG00000129197.10chr17+53292905329619533139053315595326088532614953358615336196-0.351000.008430.086692includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for RPAIN is not avaliable on ENCORE database.