PDSS2

General Information

Gene Name       : PDSS2
Gene ID             : ENSG00000164494.11
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: PDSS2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PDSS2ENSG00000164494.115.686.235.96ENCSR000AEF
HepG2PDSS2ENSG00000164494.117.1910.038.61ENCSR985KAT
K562PDSS2ENSG00000164494.118.356.027.18ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PDSS2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PDSS2 RNA is bound by 11 proteins.  







eCLIP assay for PDSS2 is not avaliable on ENCORE database.





11 proteins are bound to PDSS2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr6107780590107780752-5'-UTR,intron-Distal3.6734110.60071HepG2NCBP2
chr6107692782107692875-intron-Distal5.368886.75921K562QKI
chr6107739066107739188-intron-Distal4.2125714.94240K562KHSRP
chr6107774938107775021-intron-Distal4.489485.12844K562U2AF1
chr6107761370107761403-intron-Distal5.008314.55788HepG2QKI
chr6107708637107708697-intron-Distal4.057073.53723HepG2PTBP1
chr6107696999107697077-intron-Distal4.182843.89294K562KHSRP
chr6107687917107688007-intron-Distal4.466614.07352K562KHSRP
chr6107585308107585389-intron-Distal,intron-Proximal3.537833.10834HepG2CSTF2
chr6107697092107697179-intron-Distal4.100613.59342K562CSTF2T
chr6107754491107754551-intron-Distal3.301123.39857HepG2HNRNPM
chr6107592786107592912-intron-Distal3.346354.88847HepG2QKI
chr6107741473107741510-intron-Distal4.719385.16513HepG2HNRNPM
chr6107761162107761249-intron-Distal3.911134.52298HepG2QKI
chr6107761317107761370-intron-Distal4.404717.56258HepG2QKI
chr6107717295107717393-intron-Distal3.781273.01412K562SAFB2
chr6107742741107742849-intron-Distal3.213834.08064K562KHSRP
chr6107744335107744423-intron-Distal5.707029.73701HepG2QKI
chr6107774925107775009-intron-Distal4.635236.35380K562U2AF2
chr6107742965107743040-intron-Distal4.617455.29390K562TARDBP
chr6107744351107744439-intron-Distal5.1494012.81155K562QKI
chr6107703465107703583-intron-Distal4.626285.89032HepG2QKI
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PDSS2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PDSS2 is not available on ENCORE database.

  • 60 RBPs can affect the levels of PDSS2.  








The Knockdown/knockout RNA-Seq assay for PDSS2 is not available on ENCORE database.





60 RBPs can affect the gene expression of PDSS2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PDSS2ENSG00000164494.7317.34530419.48650-0.402602.706701.94760HepG2AKAP8L
PDSS2ENSG00000164494.7281.57600463.97760-0.720504.294903.12650HepG2BCCIP
PDSS2ENSG00000164494.7322.91680445.74440-0.465102.636502.05080HepG2BOP1
PDSS2ENSG00000164494.7323.80980417.42990-0.366402.488801.85110HepG2CKAP4
PDSS2ENSG00000164494.7292.04840409.22250-0.486702.510901.85020HepG2CPSF6
PDSS2ENSG00000164494.7555.27780430.400400.367402.606001.48330HepG2DDX1
PDSS2ENSG00000164494.7220.02860385.99980-0.810906.368305.38770HepG2DDX21
PDSS2ENSG00000164494.7935.75170698.741700.421302.689102.07120HepG2DDX3X
PDSS2ENSG00000164494.7313.51400464.70060-0.567802.241701.36470HepG2DDX59
PDSS2ENSG00000164494.7422.47930577.01430-0.449702.652602.07200HepG2EIF2S1
PDSS2ENSG00000164494.7541.66420773.76850-0.514505.457104.66080HepG2ETF1
PDSS2ENSG00000164494.7482.24560643.53120-0.416202.436201.78520HepG2FXR1
PDSS2ENSG00000164494.7290.96050426.07010-0.550303.400302.69290HepG2HNRNPA1
PDSS2ENSG00000164494.7302.13410473.93270-0.649504.552803.67780HepG2HNRNPC
PDSS2ENSG00000164494.7287.25570470.79870-0.712807.636006.66640HepG2HNRNPU
PDSS2ENSG00000164494.7291.88310606.64370-1.0555011.098009.84150HepG2IGF2BP2
PDSS2ENSG00000164494.7355.32640480.90380-0.436604.120603.24340HepG2ILF2
PDSS2ENSG00000164494.7243.39670348.93900-0.519702.452401.34820HepG2KHDRBS1
PDSS2ENSG00000164494.7407.05630610.25880-0.584203.301002.19370HepG2KHSRP
PDSS2ENSG00000164494.7374.13380647.32320-0.790906.264705.34540HepG2MATR3
PDSS2ENSG00000164494.7269.61300411.35890-0.609503.798902.85410HepG2MSI2
PDSS2ENSG00000164494.7215.38700451.47380-1.067706.880005.32070HepG2MTPAP
PDSS2ENSG00000164494.7469.84730662.54150-0.495803.157602.48350HepG2NCBP2
PDSS2ENSG00000164494.7444.63500636.21210-0.516904.864303.85740HepG2NOL12
PDSS2ENSG00000164494.7421.52750589.89940-0.484802.990002.24130HepG2PABPC4
PDSS2ENSG00000164494.7331.09830419.91330-0.342802.016301.37810HepG2PPIL4
PDSS2ENSG00000164494.7498.66460607.11950-0.283901.916301.44510HepG2PTBP1
PDSS2ENSG00000164494.7533.14780644.66840-0.274002.345501.79090HepG2PUM1
PDSS2ENSG00000164494.7461.78860644.20680-0.480304.057003.25050HepG2PUM2
PDSS2ENSG00000164494.7513.35320657.53310-0.357102.533901.93180HepG2QKI
PDSS2ENSG00000164494.7382.94500596.75070-0.640005.799004.85400HepG2RBM25
PDSS2ENSG00000164494.7504.83250675.66870-0.420503.595602.99530HepG2NELFE
PDSS2ENSG00000164494.7465.57410629.28810-0.434703.791403.08530HepG2RECQL
PDSS2ENSG00000164494.7303.36510438.19890-0.530503.157102.40530HepG2SF3B1
PDSS2ENSG00000164494.7523.42850632.09630-0.272201.807001.31200HepG2SF3B4
PDSS2ENSG00000164494.7240.99590580.41770-1.268103.937902.14820HepG2SFPQ
PDSS2ENSG00000164494.7443.56930582.28200-0.392603.488102.71520HepG2SLBP
PDSS2ENSG00000164494.7384.69360488.92190-0.345902.634402.00350HepG2SMN1
PDSS2ENSG00000164494.7328.71780487.57040-0.568802.524501.77970HepG2SNRNP70
PDSS2ENSG00000164494.7305.09950471.48200-0.627903.352502.24070HepG2SRSF3
PDSS2ENSG00000164494.7448.00900599.60940-0.420503.636102.93650HepG2SRSF5
PDSS2ENSG00000164494.7367.12310536.75490-0.548005.576104.83970HepG2SRSF9
PDSS2ENSG00000164494.7181.35660319.84150-0.818504.945303.43180HepG2STIP1
PDSS2ENSG00000164494.7248.35090343.20980-0.466702.463401.57290HepG2SUPT6H
PDSS2ENSG00000164494.7332.85660454.12840-0.448201.903301.32830HepG2SUPV3L1
PDSS2ENSG00000164494.7296.81930431.46640-0.539703.222702.44570HepG2TARDBP
PDSS2ENSG00000164494.7429.92370544.91130-0.341902.055501.33250HepG2TIA1
PDSS2ENSG00000164494.7283.87710457.43690-0.688306.026805.34110HepG2TIAL1
PDSS2ENSG00000164494.7469.66560593.28880-0.337102.070201.32450HepG2TUFM
PDSS2ENSG00000164494.7244.89570434.72950-0.828005.834104.93800HepG2U2AF1
PDSS2ENSG00000164494.7173.24530268.27100-0.630903.143502.33540HepG2UCHL5
PDSS2ENSG00000164494.7303.97770458.23010-0.592105.113203.73180HepG2UTP18
PDSS2ENSG00000164494.7333.06870430.41140-0.369902.237001.68640HepG2UTP3
PDSS2ENSG00000164494.7321.44120447.03950-0.475802.321301.65240HepG2XRN2
PDSS2ENSG00000164494.7383.48460490.30490-0.354502.708402.16540HepG2ZNF622
PDSS2ENSG00000164494.7250.34650340.48350-0.443702.450301.58690K562MATR3
PDSS2ENSG00000164494.7353.40000248.081800.510403.118802.26510K562POLR2G
PDSS2ENSG00000164494.7768.80670604.368000.347102.526901.74750K562PUF60
PDSS2ENSG00000164494.7181.06790272.23020-0.588302.459301.54580K562SF3B1
PDSS2ENSG00000164494.7235.66580324.90820-0.463302.337301.68030K562SRSF1
PDSS2ENSG00000164494.7361.50710248.846200.538703.365702.46130K562SYNCRIP
PDSS2ENSG00000164494.7112.01870237.21450-1.082506.411604.59530K562U2AF1
PDSS2ENSG00000164494.7101.74210244.93650-1.2675010.302708.75160K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PDSS2 is not available on ENCORE database.





2 RBPs can affect the splicing of PDSS2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPDSS2ENSG00000164494.7chr6-1076457591076458781075952321075954311076554011076555360.062000.008920.07413includedK562AQR
SEPDSS2ENSG00000164494.7chr6-107655401107655536107595232107595431107780193107780767-0.157000.001510.04642excludedK562UTP18

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PDSS2 is not avaliable on ENCORE database.