INTS4

General Information

Gene Name       : INTS4
Gene ID             : ENSG00000149262.16
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: INTS4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878INTS4ENSG00000149262.1626.5526.2926.42ENCSR000AEF
HepG2INTS4ENSG00000149262.1619.6327.9323.78ENCSR985KAT
K562INTS4ENSG00000149262.1625.3228.0426.68ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for INTS4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • INTS4 RNA is bound by 14 proteins.  







eCLIP assay for INTS4 is not avaliable on ENCORE database.





14 proteins are bound to INTS4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr117759491077594997-3'-UTR,CDS,intron-Distal3.248826.55799HepG2PABPN1
chr117758978377589836-3'-UTR,intron-Distal4.041233.00640HepG2ZC3H11A
chr117769004177690072-3'-UTR,CDS,intron-Distal,intron-Proximal4.241307.53358HepG2BCLAF1
chr117759487677594907-3'-UTR,CDS,intron-Distal,intron-Proximal4.143774.49585HepG2LSM11
chr117761458577614619-3'-UTR,CDS,intron-Distal,intron-Proximal4.950116.71715HepG2BCLAF1
chr117769250377692571-3'-UTR,CDS,intron-Distal,intron-Proximal4.143348.94445HepG2BCLAF1
chr117762993477630006-3'-UTR,CDS,intron-Distal3.483405.83654K562ZNF622
chr117769250377692539-3'-UTR,CDS,intron-Distal,intron-Proximal3.036245.54400K562YBX3
chr117760236477602405-3'-UTR,CDS,intron-Distal,intron-Proximal3.838363.05716HepG2PABPN1
chr117769008777690147-3'-UTR,CDS,intron-Distal3.331836.33024HepG2BCLAF1
chr117763559077635631-3'-UTR,intron-Distal3.682493.67894HepG2AQR
chr117759011577590174-3'-UTR,CDS,intron-Distal3.501514.77076HepG2LSM11
chr117761876777618827-3'-UTR,CDS,intron-Distal3.783793.14999HepG2GRWD1
chr117761875977618822-3'-UTR,CDS,intron-Distal,intron-Proximal4.870764.48364K562DDX24
chr117763558677635662-3'-UTR,intron-Distal,intron-Proximal4.131423.31283K562PRPF8
chr117763558777635631-3'-UTR,intron-Distal4.6956716.66732K562AQR
chr117759012777590174-3'-UTR,CDS,intron-Distal4.026876.43352HepG2PABPN1
chr117761258077612598-3'-UTR,CDS,intron-Distal,intron-Proximal4.730924.78529HepG2BCLAF1
chr117766979077669880-5'-UTR,CDS,intron-Distal,intron-Proximal4.2103813.37200HepG2BCLAF1
chr117767199877672071-5'-UTR,CDS,intron-Distal,intron-Proximal3.583055.83654K562ZNF622
chr117767199877672045-5'-UTR,CDS,intron-Distal,intron-Proximal4.099418.08603HepG2BCLAF1
chr117767199877672095-5'-UTR,CDS,intron-Distal,intron-Proximal3.422564.27261HepG2GRWD1
chr117767141977671437-5'-UTR,CDS,intron-Distal3.530343.68471HepG2BCLAF1
chr117767199177672055-5'-UTR,CDS,intron-Distal,intron-Proximal4.897806.36164K562DDX24
chr117766710177667109-5'-UTR,CDS,intron-Distal,intron-Proximal4.430564.04372HepG2BCLAF1
chr117766700077667032-5'-UTR,CDS,intron-Distal3.310053.28366HepG2BCLAF1
chr117766978977669808-5'-UTR,CDS,intron-Distal,intron-Proximal3.689483.30172K562DDX24
chr117767199377672096-5'-UTR,CDS,intron-Distal,intron-Proximal3.021913.91443HepG2PPIG
chr117766980877669881-5'-UTR,CDS,intron-Distal,intron-Proximal4.531734.12139K562DDX24
chr117766980177669870-5'-UTR,CDS,intron-Distal3.663954.22917HepG2PPIG
chr117767139877671419-5'-UTR,CDS,intron-Distal4.406383.02457HepG2BCLAF1
chr117770229177702370-CDS,intron-Distal,intron-Proximal4.624753.59236HepG2AQR
chr117770231877702377-CDS,intron-Distal,intron-Proximal3.401114.63311K562AQR
chr117770563577705654-CDS,intron-Distal3.966163.49332HepG2PPIG
chr117770558877705663-CDS,intron-Distal5.0809814.11848HepG2PRPF8
chr117770557677705666-CDS,intron-Distal3.781203.76553K562PRPF8
chr117767215777672184-CDS,intron-Distal4.260375.94293HepG2BCLAF1
chr117770216977702329-CDS,intron-Distal4.2321817.22952HepG2BCLAF1
chr117768037177680460-intron-Distal4.774564.77636HepG2HNRNPL
chr117770559177705629-intron-Distal5.9293511.02807K562AQR
chr117767571277675809-intron-Distal4.317746.96393HepG2PCBP2
chr117761862977618711-intron-Distal,intron-Proximal3.288113.18246K562PRPF8
chr117770562977705635-intron-Distal5.395796.75320K562AQR
chr117761770777617844-intron-Distal3.399074.93120K562KHSRP
chr117768034877680427-intron-Distal4.040953.37631K562HNRNPL
chr117768878277688854-intron-Distal,intron-Proximal3.945313.71397K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for INTS4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for INTS4 is not available on ENCORE database.

  • 33 RBPs can affect the levels of INTS4.  








The Knockdown/knockout RNA-Seq assay for INTS4 is not available on ENCORE database.





33 RBPs can affect the gene expression of INTS4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
INTS4ENSG00000149262.12466.75720601.38580-0.365603.236902.52800HepG2CKAP4
INTS4ENSG00000149262.12707.15590854.14740-0.272502.012901.44810HepG2CELF1
INTS4ENSG00000149262.12314.62560436.19720-0.471302.583701.50820HepG2EFTUD2
INTS4ENSG00000149262.12534.45380701.60860-0.392602.058401.50450HepG2EIF4A3
INTS4ENSG00000149262.12294.02900577.89700-0.9749010.142308.88780HepG2HNRNPC
INTS4ENSG00000149262.12564.17270829.30770-0.555803.522902.58440HepG2LARP4
INTS4ENSG00000149262.12521.87540708.14670-0.440302.703202.05450HepG2MAGOH
INTS4ENSG00000149262.12381.06720712.10910-0.902108.106707.07360HepG2MATR3
INTS4ENSG00000149262.12446.49740643.52190-0.527302.729001.69620HepG2PCBP2
INTS4ENSG00000149262.12520.36200635.27850-0.287901.989001.32510HepG2PRPF4
INTS4ENSG00000149262.12553.51880744.89560-0.428403.916603.29070HepG2PTBP1
INTS4ENSG00000149262.12629.93470869.30530-0.464703.865703.17410HepG2PUF60
INTS4ENSG00000149262.12735.47380922.82640-0.327403.448302.80120HepG2PUM1
INTS4ENSG00000149262.12745.34810922.13960-0.307102.204301.60310HepG2PUM2
INTS4ENSG00000149262.12374.50490621.03500-0.729703.559602.76260HepG2RAVER1
INTS4ENSG00000149262.12298.98830413.29560-0.467102.704202.09510HepG2RPS19
INTS4ENSG00000149262.12498.24720671.52490-0.430602.759301.95950HepG2RPS2
INTS4ENSG00000149262.12297.65960454.44980-0.610504.047103.20900HepG2SF3B1
INTS4ENSG00000149262.12533.68300775.43540-0.539005.565004.77640HepG2SF3B4
INTS4ENSG00000149262.12613.02960809.42630-0.400903.673603.14800HepG2SRSF1
INTS4ENSG00000149262.12682.89480858.33690-0.329902.921002.27860HepG2SRSF5
INTS4ENSG00000149262.12467.69160571.33030-0.288802.139501.51840HepG2SRSF7
INTS4ENSG00000149262.12599.84990846.33210-0.496606.261005.54700HepG2SSB
INTS4ENSG00000149262.12771.06860976.14450-0.340203.498102.81380HepG2SUCLG1
INTS4ENSG00000149262.12893.59550727.653800.296302.490901.95520HepG2TAF15
INTS4ENSG00000149262.12372.87460557.88470-0.581305.133604.49600HepG2TIAL1
INTS4ENSG00000149262.12413.27400562.80620-0.445504.010403.35620HepG2TRIM56
INTS4ENSG00000149262.12678.70390899.00100-0.405502.146801.41470HepG2UBE2L3
INTS4ENSG00000149262.12452.26010682.95340-0.594603.481102.29340HepG2XRCC6
INTS4ENSG00000149262.121551.013301300.501900.254002.686802.04320K562DDX47
INTS4ENSG00000149262.12429.25260773.69450-0.8499010.389609.29240K562HNRNPC
INTS4ENSG00000149262.12871.981501095.90660-0.329802.538801.73290K562MAGOH
INTS4ENSG00000149262.12719.899701093.65390-0.603307.435605.83100K562MATR3
INTS4ENSG00000149262.12687.50840862.99860-0.328002.076801.38280K562POLR2G
INTS4ENSG00000149262.121494.100201885.97500-0.336002.816501.99260K562PUF60
INTS4ENSG00000149262.121677.885801965.50240-0.228302.395101.50070K562PUM2
INTS4ENSG00000149262.121843.286001321.868100.479604.912004.21480K562PUS1
INTS4ENSG00000149262.12767.184701043.83800-0.444304.207103.34320K562SRSF1
INTS4ENSG00000149262.121211.47920862.702000.489705.734304.57840K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for INTS4 is not available on ENCORE database.





13 RBPs can affect the splicing of INTS4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEINTS4ENSG00000149262.12chr11-776053357760539577602726776028557761246677612597-0.110000.001200.03647excludedK562AKAP8L
SEINTS4ENSG00000149262.12chr11-776220157762219877618762776188567762986677630024-0.220000.000320.02590excludedHepG2AKAP1
SEINTS4ENSG00000149262.12chr11-7763562877635713776334017763351777635795776359380.552000.001450.09594includedK562SUPV3L1
SEINTS4ENSG00000149262.12chr11-7762907677629310776187627761885677629866776300240.079000.001950.02944includedK562PUS1
SEINTS4ENSG00000149262.12chr11-776900417769014877671998776721847769250477692622-0.137000.000060.00389excludedK562UTP18
SEINTS4ENSG00000149262.12chr11-7762907677629310776187627761885677629866776300240.096000.001240.03287includedK562AGGF1
SEINTS4ENSG00000149262.12chr11-7762907677629310776220157762219877629866776300240.456000.002710.08299includedHepG2HNRNPC
SEINTS4ENSG00000149262.12chr11-7769864977698744776925047769262277702153777023450.358000.004810.06735includedK562HNRNPC
SEINTS4ENSG00000149262.12chr11-7762907677629310776187627761885677629866776300240.234000.000330.00747includedK562HNRNPC
A3SSINTS4ENSG00000149262.12chr11-7760236477602578776023647760250877602726776028550.054000.000020.00021longerK562AQR
A3SSINTS4ENSG00000149262.12chr11-7769004177690236776900417769014877692504776926220.059000.000690.00497longerK562AQR
A3SSINTS4ENSG00000149262.12chr11-7770215377702379777021537770234577705635777057160.068000.000070.00062longerK562AQR
RIINTS4ENSG00000149262.12chr11-776354877763593877635487776357137763579577635938-0.323000.009200.08418excludedK562AGGF1
RIINTS4ENSG00000149262.12chr11-776354877763593877635487776357137763579577635938-0.384000.001000.07046excludedK562ZC3H8
RIINTS4ENSG00000149262.12chr11-7763548777635938776354877763571377635795776359380.335000.000300.04137includedK562PUM1
RIINTS4ENSG00000149262.12chr11-776354877763593877635487776357137763579577635938-0.293000.010070.05415excludedK562AQR
MXEINTS4ENSG00000149262.12chr11-77649696776498717766698777667108776393877763959377669791776698800.263000.000790.051141includedK562LARP4
MXEINTS4ENSG00000149262.12chr11-7762203277622198776290767762931077618762776188567762986677630024-0.692000.007400.071482includedK562DROSHA
MXEINTS4ENSG00000149262.12chr11-7760533577605395776124667761259777602726776028867761458577614666-0.107000.002030.062382includedK562LIN28B

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for INTS4 is not avaliable on ENCORE database.