TFRC

General Information

Gene Name : TFRC
Gene ID : ENSG00000072274.12
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: TFRC)

Not Available

Antibody Validation

View validation images for all TFRC antibodies

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	TFRC	ENSG00000072274.12	171.81	148.18	160.00	ENCSR000AEF
HepG2	TFRC	ENSG00000072274.12	154.90	184.98	169.94	ENCSR985KAT
K562	TFRC	ENSG00000072274.12	172.32	172.03	172.18	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
TFRC		13113S	4			Submitted, ENCORE2	BGHcLV45-77, Submitted, ENCORE2
TFRC		13208S	1			Submitted, ENCORE2	BGHcLV45-77, Submitted, ENCORE2

KD RNA-Seq

GeneName	Cell_Line	Method	Sample_reps	Control_reps	KD%	Status	Project
TFRC	K562	CRISPR	BGKcLV42-95,BGKcLV42-96	BGKcLV42-1,BGKcLV42-2	0.0,0.0	NotSatisfied	ENCORE2
TFRC	K562	CRISPR	BGKcLV44-79,BGKcLV44-80	BGKcLV44-1,BGKcLV44-2	10.8,31.2	NotSatisfied	ENCORE2
TFRC	K562	CRISPR	BGKcLV46-105,BGKcLV46-106	BGKcLV46-1,BGKcLV46-2		NotSatisfied	ENCORE2
TFRC	K562	CRISPR	TFRC-BGKcLV46-107,TFRC-BGKcLV46-108	NT-BGKcLV46-1,NT-BGKcLV46-2	87.5,86.4	Submitting	ENCORE2
TFRC	HepG2	CRISPR	BGHcLV45-75,BGHcLV45-76	BGHcLV45-1,BGHcLV45-2	53.8,60.2	NotSatisfied	ENCORE2
TFRC	HepG2	CRISPR	TFRC-BGHcLV45-77,TFRC-BGHcLV45-78	NT-BGHcLV45-1,NT-BGHcLV45-2	90.1,85.8	Submitting	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
TFRC	Product_ID: 13113S Lot_ID: 4 Source: Cell Signaling Technology Target Name: TFRC-human
TFRC	Product_ID: 13208S Lot_ID: 1 Source: Cell Signaling Technology Target Name: TFRC-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for TFRC is not avaliable on ENCORE database.

Proteins bound to RNA

TFRC RNA is bound by 60 proteins.

CanvasJS.com

eCLIP assay for TFRC is not avaliable on ENCORE database.

60 proteins are bound to TFRC RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr3	195789805	195789822	-	3'-UTR,CDS,intron-Distal,intron-Proximal	6.11876	400.00000	K562	SF3B4
chr3	195789503	195789574	-	3'-UTR,CDS,intron-Distal,intron-Proximal	5.30415	400.00000	K562	SF3B4
chr3	195782146	195782227	-	3'-UTR,CDS,intron-Distal,intron-Proximal	5.87184	400.00000	K562	SF3B4
chr3	195787126	195787169	-	intron-Distal,intron-Proximal	4.62506	400.00000	K562	SF3B4
chr3	195794864	195794897	-	intron-Distal,intron-Proximal	5.39543	400.00000	K562	AQR
chr3	195794859	195794864	-	intron-Distal,intron-Proximal	6.30564	400.00000	K562	AQR
chr3	195799712	195799757	-	intron-Distal	7.68319	400.00000	K562	LSM11
chr3	195799689	195799711	-	intron-Distal	8.33145	113.22412	K562	LSM11
chr3	195789723	195789807	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.66316	87.63218	K562	GPKOW
chr3	195789822	195789859	-	intron-Distal,intron-Proximal	6.86029	86.70799	K562	SF3B4
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 463 entries

eCLIP assay for TFRC is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for TFRC is not available on ENCORE database.
174 RBPs can affect the levels of TFRC.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for TFRC is not available on ENCORE database.

174 RBPs can affect the gene expression of TFRC :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
TFRC	ENSG00000072274.8	2322.29160	23348.84020	-3.32970	186.98320	182.61210	HepG2	IGF2BP2
TFRC	ENSG00000072274.8	19519.12570	6408.82790	1.60670	111.25570	107.70470	K562	RBM15
TFRC	ENSG00000072274.8	29078.06250	6577.26010	2.14430	104.18570	100.68840	K562	PUS1
TFRC	ENSG00000072274.8	10161.18720	24958.76030	-1.29650	100.59540	98.54090	HepG2	NELFE
TFRC	ENSG00000072274.8	3489.25840	11404.52610	-1.70860	78.47700	76.08260	HepG2	HNRNPA1
TFRC	ENSG00000072274.8	10442.81840	22427.33750	-1.10270	72.77920	70.87620	HepG2	PTBP1
TFRC	ENSG00000072274.8	16679.36600	6373.99350	1.38770	70.64530	67.87310	K562	AGGF1
TFRC	ENSG00000072274.8	8716.93900	16858.59840	-0.95160	69.09320	66.90940	HepG2	PUS1
TFRC	ENSG00000072274.8	11865.79140	23348.21410	-0.97650	65.07900	62.95000	HepG2	SF3B4
TFRC	ENSG00000072274.8	7913.07070	15835.11840	-1.00080	63.19160	61.09700	HepG2	DKC1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 226 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for TFRC is not available on ENCORE database.

21 RBPs can affect the splicing of TFRC :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
SE	TFRC	ENSG00000072274.8	chr3	-	195798266	195798408	195796325	195796439	195798873	195799061	-0.08700	0.00000	excluded	K562	AQR
SE	TFRC	ENSG00000072274.8	chr3	-	195785154	195785236	195781981	195782172	195785444	195785503	-0.05700	0.00006	excluded	K562	PUS1
SE	TFRC	ENSG00000072274.8	chr3	-	195785154	195785236	195781950	195782172	195785444	195785503	-0.13700	0.00000	excluded	K562	U2AF1
SE	TFRC	ENSG00000072274.8	chr3	-	195785154	195785236	195781950	195782172	195785444	195785503	-0.14100	0.00000	excluded	K562	U2AF2
SE	TFRC	ENSG00000072274.8	chr3	-	195790095	195790232	195789724	195789810	195791179	195791299	0.28500	0.00000	included	K562	HNRNPC
A3SS	TFRC	ENSG00000072274.8	chr3	-	195781950	195782190	195781950	195782172	195785154	195785236	0.07700	0.00001	longer	K562	U2AF2
A3SS	TFRC	ENSG00000072274.8	chr3	-	195789724	195789935	195789724	195789810	195791179	195791299	0.06000	0.00000	longer	K562	AQR
A3SS	TFRC	ENSG00000072274.8	chr3	-	195803934	195804105	195803934	195803993	195808913	195808961	0.34300	0.00001	longer	K562	AQR
A3SS	TFRC	ENSG00000072274.8	chr3	-	195798957	195799061	195798957	195799023	195800800	195801018	0.06200	0.00000	longer	K562	AQR
A3SS	TFRC	ENSG00000072274.8	chr3	-	195800800	195801018	195800800	195800996	195802029	195802231	0.07600	0.00000	longer	K562	AQR

Showing 1 to 10 of 40 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

TFRC

General Information

Functions

Localization

Domains (AlphaFold: TFRC)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for TFRC is not avaliable on ENCORE database.

60 proteins are bound to TFRC RNA:

eCLIP assay for TFRC is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for TFRC is not available on ENCORE database.

174 RBPs can affect the gene expression of TFRC :

The Knockdown/knockout RNA-Seq assay for TFRC is not available on ENCORE database.

21 RBPs can affect the splicing of TFRC :

The Knockdown/knockout RNA-Seq assay for TFRC is not avaliable on ENCORE database.