RAVER1

General Information

Gene Name : RAVER1
Gene ID : ENSG00000161847.13
Essential Gene : No

Functions

Splicing regulation

Localization(RBPImage: RAVER1)

Nuclei
Nucleoplasm
Unknown Nuclear Territory
Cytoplasm
Compartment/Organelle
Mitochondria

Domains (AlphaFold: RAVER1)

RRM

Antibody Validation

Bethyl Labs: A303-939A

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	RAVER1	ENSG00000161847.13	0.65	3.25	1.95	ENCSR000AEF
HepG2	RAVER1	ENSG00000161847.13	32.28	3.83	18.05	ENCSR985KAT
K562	RAVER1	ENSG00000161847.13	26.49	6.26	16.38	ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	RAVER1-BGKLV08-K562	ENCSR904BCZ	RAVER1	K562	Released		ENCSR344XID	shRNA	KD% = 79.3,75.8
knockdown followed by RNA-seq	RAVER1-BGHLV14-HepG2	ENCSR576GOW	RAVER1	HepG2	Released		ENCSR491FOC	shRNA	KD% = no clear band,no clear band

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
RAVER1	ENCAB846NHA	A303-939A	1			Released, ENCODE3		BGKLV08-41, Released, ENCODE3

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project	Note
RAVER1	K562	shRNA	ENCSR904BCZ	ENCSR344XID	RAVER1-LV08-41,RAVER1-LV08-42	Nontarget-LV08-1_00003531,nontarget-LV08-2_00003531	79.3,75.8	Released	ENCODE3
RAVER1	HepG2	shRNA	ENCSR576GOW	ENCSR491FOC	RAVER1_BGHLV14-33,RAVER1_BGHLV14-34	NT_BGHLV14-1,NT_BGHLV14-2	no clear band,no clear band	Released	ENCODE3

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

RAVER1: Click to RBP Image Database

Nuclei

Nucleoplasm

Unknown Nuclear Territory

Cytoplasm

Compartment/Organelle

Mitochondria

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
RAVER1	Product_ID: A303-939A Lot_ID: 1 Source: Bethyl Labs Target Name: RAVER1-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for RAVER1 is not avaliable on ENCORE database.

Proteins bound to RNA

RAVER1 RNA is bound by 33 proteins.

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eCLIP assay for RAVER1 is not avaliable on ENCORE database.

33 proteins are bound to RAVER1 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr19	10427490	10427589	-	3'-UTR,intron-Distal	5.14499	28.18774	K562	PCBP1
chr19	10432642	10432703	-	intron-Distal	5.72040	24.17576	K562	AGGF1
chr19	10428005	10428059	-	3'-UTR,intron-Distal	3.98050	23.96229	K562	PABPC4
chr19	10432704	10432804	-	intron-Distal	4.88234	20.25903	K562	AGGF1
chr19	10439567	10439788	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.54993	19.74151	K562	FXR2
chr19	10427509	10427535	-	3'-UTR,intron-Distal	4.32479	17.93539	K562	IGF2BP2
chr19	10427603	10427657	-	3'-UTR,intron-Distal	3.48041	17.69923	K562	IGF2BP2
chr19	10427535	10427582	-	3'-UTR,intron-Distal	4.15826	17.23550	K562	IGF2BP2
chr19	10427127	10427176	-	3'-UTR,intron-Distal	4.48730	17.02551	K562	PCBP1
chr19	10432145	10432235	-	CDS,intron-Distal,intron-Proximal	4.79458	16.53416	HepG2	PRPF8
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 144 entries

eCLIP assay for RAVER1 is not avaliable on ENCORE database.

Diffrential Expression

7,131 differentially expressed genes after Knockdown/Knockout RAVER1 protein.

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118 RBPs can affect the levels of RAVER1.

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7,131 differentially expressed genes after Knockdown/Knockout RAVER1 protein :

Only display 100 entries as example. Please click "View All" button to see all 7,131 entries.

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Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
IFRD1	ENSG00000006652.9	3459.03950	491.68830	2.81450	53.34810	50.75240	HepG2	RAVER1
PAX6	ENSG00000007372.16	365.18830	21.81220	4.06530	40.90020	38.55350	HepG2	RAVER1
MGST1	ENSG00000008394.8	368.25730	1907.57250	-2.37300	35.98340	33.75360	HepG2	RAVER1
NCAPD2	ENSG00000010292.8	1006.60630	3525.13710	-1.80820	24.70490	22.80530	HepG2	RAVER1
MYH16	ENSG00000002079.8	148.05170	6.12700	4.59470	24.14820	22.26930	HepG2	RAVER1
GCLC	ENSG00000001084.6	3783.25310	1132.77420	1.73970	23.46960	21.62050	HepG2	RAVER1
IDS	ENSG00000010404.13	2782.02550	828.94960	1.74670	22.78920	20.95860	HepG2	RAVER1
TNFRSF12A	ENSG00000006327.9	1787.80170	376.59020	2.24700	20.49430	18.74660	HepG2	RAVER1
PROM1	ENSG00000007062.7	2056.81760	669.96610	1.61820	19.12010	17.43180	HepG2	RAVER1
CD9	ENSG00000010278.7	825.34410	236.97900	1.80010	18.33500	16.67760	HepG2	RAVER1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 100 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

118 RBPs can affect the gene expression of RAVER1 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
RAVER1	ENSG00000161847.9	1177.58500	329.23420	1.83850	52.14000	47.76910	K562	TIA1
RAVER1	ENSG00000161847.9	286.96750	1106.17160	-1.94660	38.07280	35.89850	HepG2	PRPF4
RAVER1	ENSG00000161847.9	907.07100	401.94450	1.17410	27.68980	25.99160	HepG2	SRSF5
RAVER1	ENSG00000161847.9	1036.85080	344.03400	1.59150	25.35080	23.42540	K562	PTBP1
RAVER1	ENSG00000161847.9	1087.02230	354.07290	1.61820	24.52170	21.79000	K562	MAGOH
RAVER1	ENSG00000161847.9	966.90700	390.34280	1.30850	22.36870	20.75740	HepG2	SLBP
RAVER1	ENSG00000161847.9	799.73020	329.66800	1.27840	19.35340	16.91410	K562	RBM22
RAVER1	ENSG00000161847.9	966.85990	1557.07790	-0.68750	18.15320	16.77560	HepG2	CKAP4
RAVER1	ENSG00000161847.9	1092.30580	341.28570	1.67820	17.19570	15.13230	K562	TARDBP
RAVER1	ENSG00000161847.9	1525.87350	2667.50020	-0.80590	16.76650	14.62480	K562	WDR3
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 135 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for RAVER1 is not available on ENCORE database.

9 RBPs can affect the splicing of RAVER1 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
MXE	RAVER1	ENSG00000161847.9	chr19	-	10434050	10434242	10439317	10439787	10433820	10433950	10441135	10441202	-0.25700	0.00000	0.00005	2included	K562	RBM22
MXE	RAVER1	ENSG00000161847.9	chr19	-	10434050	10434242	10439317	10439787	10433820	10433950	10441135	10441202	-0.30700	0.00000	0.00000	2included	K562	TIA1
MXE	RAVER1	ENSG00000161847.9	chr19	-	10434050	10434242	10439317	10439787	10433820	10433950	10441135	10441202	-0.28700	0.00000	0.00002	2included	K562	IGF2BP2
MXE	RAVER1	ENSG00000161847.9	chr19	-	10434050	10434242	10439317	10439787	10433820	10433950	10441135	10441202	-0.19700	0.00001	0.00061	2included	K562	PRPF8
MXE	RAVER1	ENSG00000161847.9	chr19	-	10434050	10434242	10439317	10439787	10433820	10433950	10441135	10441202	-0.17200	0.00004	0.00548	2included	K562	TRA2A
SE	RAVER1	ENSG00000161847.9	chr19	-	10431723	10431935			10431330	10431627	10432206	10432294	-0.11100	0.00012	0.00194	excluded	K562	AQR
MXE	RAVER1	ENSG00000161847.9	chr19	-	10434050	10434242	10439317	10439787	10433820	10433950	10441135	10441202	-0.23000	0.00117	0.06177	2included	HepG2	XPO5
RI	RAVER1	ENSG00000161847.9	chr19	-	10431330	10431627			10431330	10431458	10431533	10431627	0.06800	0.00275	0.01683	included	K562	AQR
RI	RAVER1	ENSG00000161847.9	chr19	-	10431330	10431627			10431330	10431458	10431533	10431627	0.06300	0.00904	0.07272	included	HepG2	U2AF1
RI	RAVER1	ENSG00000161847.9	chr19	-	10431330	10431627			10431330	10431458	10431533	10431627	0.14400	0.01615	0.09222	included	HepG2	SF3B4

Showing 1 to 10 of 10 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

RAVER1

General Information

Functions

Localization(RBPImage: RAVER1)

Domains (AlphaFold: RAVER1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for RAVER1 is not avaliable on ENCORE database.

33 proteins are bound to RAVER1 RNA:

eCLIP assay for RAVER1 is not avaliable on ENCORE database.

Diffrential Expression

7,131 differentially expressed genes after Knockdown/Knockout RAVER1 protein :

118 RBPs can affect the gene expression of RAVER1 :

The Knockdown/knockout RNA-Seq assay for RAVER1 is not available on ENCORE database.

9 RBPs can affect the splicing of RAVER1 :

The Knockdown/knockout RNA-Seq assay for RAVER1 is not avaliable on ENCORE database.