PARN

General Information

Gene Name : PARN
Gene ID : ENSG00000140694.16
Essential Gene : No

Functions

RNA stability & decay

Localization

Not Available

Domains (AlphaFold: PARN)

Nuclease

Antibody Validation

GeneTex: GTX115020

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	PARN	ENSG00000140694.16	52.37	44.73	48.55	ENCSR000AEF
HepG2	PARN	ENSG00000140694.16	29.10	46.73	37.91	ENCSR985KAT
K562	PARN	ENSG00000140694.16	33.93	34.53	34.23	ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	PARN-BGKLV24-K562	ENCSR306IOF	PARN	K562	Released		ENCSR667PLJ	shRNA	KD% = 81.4,82.6
knockdown followed by RNA-seq	PARN-BGHLV20-HepG2	ENCSR825QXH	PARN	HepG2	Released		ENCSR305XWT	shRNA	KD% = 84.6,94.7

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
PARN	ENCAB392QEW	GTX115020	40884			Released, ENCODE3	BGHLV20-47, Released, ENCODE3	BGKLV24-43, Released, ENCODE3

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
PARN	K562	shRNA	ENCSR306IOF	ENCSR667PLJ	PARN_BGKLV24_43_17622,PARN_BGKLV24_44_17623	non-target_BGKLV24_1_17594,non-target_BGKLV24_2_17595	81.4,82.6	Released	ENCODE3
PARN	HepG2	shRNA	ENCSR825QXH	ENCSR305XWT	PARN-BGHLV20-47_17730,PARN-BGHLV20-48_17731	non-target-BGHLV20-1_17706,non-target-BGHLV20-2_17707	84.6,94.7	Released	ENCODE3
PARN	293T	shRNA			BG293LV01-35,BG293LV01-36	BG293LV01-1,BG293LV01-2		NotSatisfied	ENCORE2
PARN	293T	shRNA			PARN-BG293LV02-33,PARN-BG293LV02-34	NT-BG293LV02-1,NT-BG293LV02-2	,	Revoked	ENCORE2
PARN	293T	shRNA			PARN-BG293LV06-27,PARN-BG293LV06-28	NT-BG293LV06-1,NT-BG293LV06-2	,	Sequenced	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
PARN	Product_ID: GTX115020 Lot_ID: 40884 Source: GeneTex Target Name: PARN-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for PARN is not avaliable on ENCORE database.

Proteins bound to RNA

PARN RNA is bound by 37 proteins.

eCLIP assay for PARN is not avaliable on ENCORE database.

37 proteins are bound to PARN RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr16	14698002	14698070	-	3'-UTR,CDS,intron-Distal,intron-Proximal	5.17764	8.18727	K562	ZNF622
chr16	14687114	14687194	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.71398	5.06115	HepG2	PRPF8
chr16	14530408	14530422	-	3'-UTR,intron-Distal,intron-Proximal	5.47587	22.31256	K562	LIN28B
chr16	14693765	14693812	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.39341	5.23038	K562	ZNF622
chr16	14529788	14529845	-	3'-UTR,intron-Distal	4.10853	20.59030	K562	EIF4G2
chr16	14687127	14687200	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.53316	4.77019	K562	BUD13
chr16	14529675	14529788	-	3'-UTR,intron-Distal	5.14644	23.94412	K562	EIF4G2
chr16	14529691	14529828	-	3'-UTR,intron-Distal	4.57075	18.76048	K562	TARDBP
chr16	14530356	14530408	-	3'-UTR,intron-Distal,intron-Proximal	5.61332	24.55194	K562	LIN28B
chr16	14530272	14530382	-	3'-UTR,intron-Distal,intron-Proximal	4.93393	5.74792	HepG2	SUB1
chr16	14529786	14529859	-	3'-UTR,intron-Distal	3.14729	3.06571	HepG2	IGF2BP1
chr16	14530428	14530468	-	3'-UTR,intron-Distal,intron-Proximal	4.17740	4.23668	K562	LIN28B
chr16	14530389	14530421	-	3'-UTR,intron-Distal,intron-Proximal	5.20465	4.31023	HepG2	LIN28B
chr16	14693761	14693810	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.49279	8.47761	HepG2	BCLAF1
chr16	14529674	14529786	-	3'-UTR,intron-Distal	3.55050	3.15019	HepG2	IGF2BP1
chr16	14529738	14529784	-	3'-UTR,intron-Distal	3.23989	9.44535	K562	UPF1
chr16	14529696	14529796	-	3'-UTR,intron-Distal	3.31737	5.36742	K562	IGF2BP1
chr16	14724053	14724113	-	5'-UTR,intron-Distal,intron-Proximal	4.70347	8.90399	HepG2	DDX3X
chr16	14723453	14723481	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.11728	5.64813	K562	DDX24
chr16	14722065	14722109	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.21892	14.73407	HepG2	PPIG
chr16	14722040	14722109	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.05627	3.11443	K562	MTPAP
chr16	14702917	14702962	-	5'-UTR,CDS,intron-Distal	4.10621	6.72556	HepG2	PPIG
chr16	14723403	14723493	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.04298	5.47590	K562	PRPF8
chr16	14720969	14721006	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.00434	5.79926	HepG2	BCLAF1
chr16	14724060	14724117	-	5'-UTR,intron-Distal,intron-Proximal	3.41071	6.40214	HepG2	NCBP2
chr16	14722028	14722092	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.04826	5.01560	K562	UCHL5
chr16	14722080	14722102	-	5'-UTR,CDS,intron-Distal	4.53034	7.09561	HepG2	BCLAF1
chr16	14723963	14724060	-	5'-UTR,CDS,intron-Distal	3.07621	6.44860	HepG2	NCBP2
chr16	14722036	14722109	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.17188	6.53346	K562	ZNF622
chr16	14722058	14722109	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.30068	6.81381	K562	DDX24
chr16	14704607	14704662	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.73288	9.08790	HepG2	BCLAF1
chr16	14723978	14724056	-	5'-UTR,CDS,intron-Distal	6.29921	10.63869	K562	DDX3X
chr16	14723394	14723455	-	5'-UTR,CDS,intron-Distal,intron-Proximal	5.81979	10.48996	K562	AQR
chr16	14702919	14702978	-	5'-UTR,CDS,intron-Distal	3.66209	10.68403	HepG2	BCLAF1
chr16	14702089	14702151	-	5'-UTR,CDS,intron-Distal,intron-Proximal	5.10196	7.70650	HepG2	PRPF8
chr16	14720995	14721058	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.82389	5.09028	HepG2	U2AF2
chr16	14722032	14722073	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.67486	8.99805	HepG2	BCLAF1
chr16	14722033	14722065	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.82774	5.90680	HepG2	PPIG
chr16	14722031	14722109	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.09238	7.54832	HepG2	GRWD1
chr16	14678226	14678280	-	CDS,intron-Distal,intron-Proximal	4.09781	7.14937	K562	ZNF622
chr16	14721130	14721161	-	CDS,intron-Distal,intron-Proximal	3.35188	3.66187	K562	ZNF622
chr16	14721143	14721162	-	CDS,intron-Distal,intron-Proximal	3.56002	4.34695	HepG2	BCLAF1
chr16	14540781	14540926	-	CDS,intron-Distal,intron-Proximal	3.13070	3.67092	HepG2	G3BP1
chr16	14645876	14645925	-	CDS,intron-Distal,intron-Proximal	3.51593	5.86107	HepG2	PPIG
chr16	14645886	14645912	-	CDS,intron-Distal	4.30535	6.65960	HepG2	BCLAF1
chr16	14649510	14649564	-	CDS,intron-Distal,intron-Proximal	3.60048	4.19763	K562	DDX24
chr16	14645920	14645944	-	CDS,intron-Distal	4.02688	4.51739	HepG2	BCLAF1
chr16	14613055	14613162	-	intron-Distal	5.54073	24.75468	HepG2	DDX59
chr16	14712452	14712517	-	intron-Distal	4.07437	3.80060	HepG2	HNRNPC
chr16	14613092	14613170	-	intron-Distal	6.54254	47.46109	HepG2	PCBP2
chr16	14616550	14616627	-	intron-Distal	3.67750	7.20487	HepG2	SUGP2
chr16	14556463	14556534	-	intron-Distal	4.71309	4.90095	K562	PTBP1
chr16	14613097	14613159	-	intron-Distal	4.53626	3.72818	HepG2	ILF3
chr16	14593134	14593261	-	intron-Distal	5.27269	9.28034	HepG2	PCBP2
chr16	14641523	14641576	-	intron-Distal	4.35506	5.25941	HepG2	HNRNPC
chr16	14642754	14642866	-	intron-Distal	6.81240	55.58646	HepG2	PCBP2
chr16	14639331	14639393	-	intron-Distal	4.09774	3.71397	K562	KHSRP
chr16	14589998	14590086	-	intron-Distal	4.03602	3.51329	HepG2	MATR3
chr16	14644606	14644745	-	intron-Distal	3.39192	3.51696	K562	KHSRP
chr16	14616363	14616409	-	intron-Distal	4.51669	4.66737	HepG2	MATR3
chr16	14639957	14640030	-	intron-Distal	3.97155	3.92684	K562	KHSRP
chr16	14717778	14717854	-	intron-Distal	3.46865	5.25527	HepG2	U2AF2
chr16	14680641	14680718	-	intron-Distal	3.22102	3.06005	HepG2	QKI
chr16	14642750	14642846	-	intron-Distal	4.09946	4.05367	K562	ILF3
chr16	14613056	14613158	-	intron-Distal	3.69986	3.06194	K562	ILF3
chr16	14689140	14689216	-	intron-Distal	4.52113	6.23114	K562	TARDBP
chr16	14645584	14645648	-	intron-Distal	4.06661	5.60471	HepG2	U2AF2
chr16	14616113	14616195	-	intron-Distal	3.18003	4.89395	HepG2	SUGP2
chr16	14616627	14616673	-	intron-Distal	4.43276	5.59955	HepG2	SUGP2
chr16	14556471	14556530	-	intron-Distal	4.27076	3.62238	HepG2	MATR3
chr16	14557043	14557090	-	intron-Distal	4.18505	3.54208	HepG2	SUGP2
chr16	14616316	14616398	-	intron-Distal	3.09372	5.22993	HepG2	SUGP2
chr16	14723676	14723745	-	intron-Distal	3.74856	3.17235	HepG2	HNRNPK
chr16	14633297	14633418	-	intron-Distal	3.32585	3.50045	HepG2	SFPQ
chr16	14710588	14710602	-	intron-Distal	3.04287	4.83241	HepG2	HNRNPC
chr16	14645484	14645559	-	intron-Distal	3.19072	3.29251	K562	KHSRP
chr16	14556947	14557001	-	intron-Distal	4.06250	3.16028	HepG2	SUGP2
chr16	14571607	14571707	-	intron-Distal	7.50743	39.08438	HepG2	PCBP2
chr16	14616562	14616646	-	intron-Distal	5.40416	10.69478	HepG2	MATR3
chr16	14723536	14723583	-	intron-Distal,intron-Proximal	3.66346	5.09328	HepG2	SF3B4
chr16	14616442	14616502	-	intron-Distal	4.58865	7.14115	HepG2	XPO5
chr16	14642208	14642283	-	intron-Distal	4.18510	9.06934	K562	KHSRP
chr16	14642866	14642878	-	intron-Distal	3.93215	3.23894	HepG2	PCBP2
chr16	14642283	14642382	-	intron-Distal	3.68397	9.20203	K562	KHSRP
chr16	14530645	14530688	-	intron-Distal	4.08171	3.50006	HepG2	SF3B4
chr16	14556430	14556526	-	intron-Distal	3.28738	5.19856	HepG2	PTBP1
chr16	14617290	14617366	-	intron-Distal	4.09646	3.27946	HepG2	HNRNPM
chr16	14573027	14573092	-	intron-Distal	4.67933	5.58899	HepG2	ILF3
chr16	14645784	14645863	-	intron-Distal,intron-Proximal	5.04340	7.35412	HepG2	TIAL1
chr16	14710552	14710588	-	intron-Distal	3.67119	6.39201	HepG2	HNRNPC
chr16	14556608	14556678	-	intron-Distal	3.40745	4.35402	HepG2	SUGP2
chr16	14645764	14645842	-	intron-Distal,intron-Proximal	3.47510	4.46957	K562	TIA1
chr16	14613091	14613189	-	intron-Distal	4.33744	7.56829	HepG2	HNRNPK
chr16	14616673	14616739	-	intron-Distal	3.60570	7.75281	HepG2	SUGP2
chr16	14572979	14573027	-	intron-Distal	4.51218	6.03523	HepG2	ILF3
chr16	14642749	14642839	-	intron-Distal	4.08916	5.65933	HepG2	DDX59
chr16	14642764	14642877	-	intron-Distal	5.18933	9.27360	HepG2	HNRNPK
chr16	14657210	14657338	-	intron-Distal	3.14158	6.53997	HepG2	HNRNPL
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for PARN is not avaliable on ENCORE database.

Diffrential Expression

4,335 differentially expressed genes after Knockdown/Knockout PARN protein.

67 RBPs can affect the levels of PARN.

4,335 differentially expressed genes after Knockdown/Knockout PARN protein :

Only display 100 entries as example. Please click "View All" button to see all 4,335 entries.

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
C1orf112	ENSG00000000460.12	255.53630	360.37180	-0.49600	2.75900	1.91200	HepG2	PARN
NFYA	ENSG00000001167.10	831.55360	1019.92600	-0.29460	2.76930	1.92090	HepG2	PARN
NIPAL3	ENSG00000001461.12	164.65530	283.37850	-0.78330	5.73220	4.57430	HepG2	PARN
SEMA3F	ENSG00000001617.7	426.34480	307.86880	0.46960	3.45190	2.51550	HepG2	PARN
CYP51A1	ENSG00000001630.11	1547.15860	2932.21370	-0.92240	34.42360	32.11500	HepG2	PARN
LAP3	ENSG00000002549.8	2365.03620	1903.92020	0.31280	4.53960	3.48460	HepG2	PARN
CD99	ENSG00000002586.13	2186.31290	1672.08120	0.38680	4.88210	3.79530	HepG2	PARN
M6PR	ENSG00000003056.3	3029.74130	2191.51890	0.46720	10.08450	8.63700	HepG2	PARN
ALS2	ENSG00000003393.10	1031.84420	1209.82920	-0.22960	2.03720	1.30110	HepG2	PARN
CASP10	ENSG00000003400.10	404.01720	658.21900	-0.70420	9.19130	7.79200	HepG2	PARN
CFLAR	ENSG00000003402.15	1181.62570	1581.03900	-0.42010	6.37990	5.17460	HepG2	PARN
TFPI	ENSG00000003436.10	8914.66280	7625.57830	0.22520	3.60660	2.65190	HepG2	PARN
SLC7A2	ENSG00000003989.12	3464.84640	5043.62420	-0.54170	15.58300	13.85400	HepG2	PARN
ARF5	ENSG00000004059.6	910.65210	725.52510	0.32780	3.12940	2.23330	HepG2	PARN
POLDIP2	ENSG00000004142.7	1519.04070	1764.89620	-0.21640	2.21210	1.44680	HepG2	PARN
PLXND1	ENSG00000004399.8	2440.84310	1634.94480	0.57800	6.24160	5.04810	HepG2	PARN
AK2	ENSG00000004455.12	2766.05470	3223.45680	-0.22080	2.78800	1.93670	HepG2	PARN
RBM6	ENSG00000004534.10	4012.75110	2987.72360	0.42540	3.88030	2.89640	HepG2	PARN
SLC25A13	ENSG00000004864.9	1275.02240	1486.53990	-0.22140	2.09900	1.35370	HepG2	PARN
DVL2	ENSG00000004975.7	495.44520	619.46720	-0.32230	2.40390	1.61040	HepG2	PARN
DHX33	ENSG00000005100.8	955.46820	1329.62780	-0.47670	7.24220	5.97570	HepG2	PARN
ACSM3	ENSG00000005187.7	977.83000	662.15390	0.56230	8.06110	6.73540	HepG2	PARN
AC004381.6	ENSG00000005189.15	183.35650	259.32570	-0.50010	2.63510	1.80530	HepG2	PARN
SPPL2B	ENSG00000005206.12	244.80720	179.63700	0.44650	2.10950	1.36180	HepG2	PARN
ZNF195	ENSG00000005801.12	824.10530	503.49200	0.71080	10.78100	9.29000	HepG2	PARN
MYCBP2	ENSG00000005810.13	1029.75460	1321.38410	-0.35970	4.48200	3.43420	HepG2	PARN
FBXL3	ENSG00000005812.6	300.76670	426.23320	-0.50300	2.26460	1.49130	HepG2	PARN
ITGAL	ENSG00000005844.13	17.23340	41.89510	-1.28160	2.38950	1.59720	HepG2	PARN
LAMP2	ENSG00000005893.11	3581.56090	4062.66250	-0.18180	2.16790	1.41030	HepG2	PARN
ASB4	ENSG00000005981.8	517.42160	213.78420	1.27510	20.26710	18.39020	HepG2	PARN
GDE1	ENSG00000006007.7	2836.49640	1774.03960	0.67700	19.28280	17.43180	HepG2	PARN
TMEM132A	ENSG00000006118.10	572.91500	418.09380	0.45440	2.91230	2.04530	HepG2	PARN
AP2B1	ENSG00000006125.12	3555.88350	4420.57100	-0.31400	5.60290	4.45670	HepG2	PARN
CX3CL1	ENSG00000006210.6	1944.19470	1350.57070	0.52550	6.10370	4.92320	HepG2	PARN
TNFRSF12A	ENSG00000006327.9	670.11590	422.07130	0.66680	8.43100	7.07910	HepG2	PARN
MAP3K9	ENSG00000006432.11	425.89010	620.96910	-0.54400	5.68410	4.52950	HepG2	PARN
PHTF2	ENSG00000006576.12	214.91640	401.52320	-0.90170	9.55780	8.13980	HepG2	PARN
ELAC2	ENSG00000006744.14	950.30490	793.94550	0.25930	2.15540	1.40060	HepG2	PARN
ARSD	ENSG00000006756.11	350.66530	232.08680	0.59530	4.35050	3.31830	HepG2	PARN
ADIPOR2	ENSG00000006831.9	2446.00530	2991.34900	-0.29040	4.36710	3.33230	HepG2	PARN
PROM1	ENSG00000007062.7	953.04500	623.66970	0.61170	9.17340	7.77500	HepG2	PARN
CCDC124	ENSG00000007080.6	202.78860	117.35830	0.78900	4.42120	3.38020	HepG2	PARN
KIAA0100	ENSG00000007202.10	3090.09820	3506.43000	-0.18240	2.11620	1.36780	HepG2	PARN
GAS7	ENSG00000007237.14	148.38320	68.36530	1.11790	5.84660	4.68330	HepG2	PARN
TRAPPC6A	ENSG00000007255.6	77.80920	44.48950	0.80640	2.09690	1.35210	HepG2	PARN
PAX6	ENSG00000007372.16	87.57710	45.94350	0.93060	2.81430	1.95910	HepG2	PARN
CDK11A	ENSG00000008128.18	538.96020	403.30110	0.41820	3.22010	2.31370	HepG2	PARN
ADAM22	ENSG00000008277.10	156.12500	225.77520	-0.53220	2.62230	1.79410	HepG2	PARN
SPAG9	ENSG00000008294.16	2600.09870	3208.86490	-0.30350	4.83430	3.75190	HepG2	PARN
PLEKHG6	ENSG00000008323.11	105.02350	180.74730	-0.78330	3.20790	2.30310	HepG2	PARN
MGST1	ENSG00000008394.8	1256.48800	1926.69810	-0.61670	13.86030	12.21330	HepG2	PARN
ST3GAL1	ENSG00000008513.10	793.09200	1128.70950	-0.50910	7.44360	6.16480	HepG2	PARN
IL32	ENSG00000008517.12	2039.74280	1564.68090	0.38240	3.00880	2.12950	HepG2	PARN
SEC62	ENSG00000008952.12	2861.28720	2359.73150	0.27790	3.97060	2.97570	HepG2	PARN
RPS20	ENSG00000008988.5	6193.20530	4382.95570	0.49870	14.05360	12.39400	HepG2	PARN
UBE3C	ENSG00000009335.13	979.77000	1292.95170	-0.40020	5.26330	4.14410	HepG2	PARN
VTA1	ENSG00000009844.11	1594.28310	1877.23750	-0.23570	2.58220	1.76120	HepG2	PARN
BAZ1B	ENSG00000009954.6	2297.39220	2709.96090	-0.23830	2.99880	2.12100	HepG2	PARN
UQCRC1	ENSG00000010256.6	1991.04200	2830.14590	-0.50740	11.48310	9.95010	HepG2	PARN
NCAPD2	ENSG00000010292.8	2603.30490	4080.70990	-0.64850	20.32290	18.44310	HepG2	PARN
FYN	ENSG00000010810.13	1269.63470	1013.03530	0.32560	3.68740	2.72450	HepG2	PARN
TSPAN9	ENSG00000011105.7	568.92600	726.19270	-0.35210	2.17550	1.41630	HepG2	PARN
MBTD1	ENSG00000011258.11	993.31940	1287.64940	-0.37440	4.69700	3.62750	HepG2	PARN
UTP18	ENSG00000011260.9	677.42610	826.00660	-0.28610	2.36260	1.57430	HepG2	PARN
RNF216	ENSG00000011275.14	1029.85260	846.19860	0.28330	2.65560	1.82280	HepG2	PARN
SYT7	ENSG00000011347.5	71.77690	169.10510	-1.23630	7.66710	6.37010	HepG2	PARN
LARS2	ENSG00000011376.5	675.44590	876.68180	-0.37620	3.50510	2.56270	HepG2	PARN
ANLN	ENSG00000011426.6	1858.30910	2684.47380	-0.53060	12.23650	10.66410	HepG2	PARN
WIZ	ENSG00000011451.13	435.06510	295.67050	0.55710	4.62740	3.56470	HepG2	PARN
BRCA1	ENSG00000012048.15	713.42380	862.10880	-0.27310	2.23680	1.46780	HepG2	PARN
ERCC1	ENSG00000012061.11	633.80740	453.73040	0.48210	3.13040	2.23400	HepG2	PARN
CD22	ENSG00000012124.10	40.77530	15.04060	1.43870	2.74250	1.89810	HepG2	PARN
SEMA3B	ENSG00000012171.13	2885.81970	1594.07150	0.85620	29.79570	27.60630	HepG2	PARN
MBTPS2	ENSG00000012174.7	441.02840	772.32050	-0.80830	12.86030	11.25520	HepG2	PARN
NR1H4	ENSG00000012504.9	209.98930	681.79370	-1.69900	39.95830	37.51190	HepG2	PARN
ELOVL5	ENSG00000012660.9	2833.56020	2324.34800	0.28570	3.10620	2.21300	HepG2	PARN
MAN2B2	ENSG00000013288.4	770.41950	484.27910	0.66970	9.32020	7.91570	HepG2	PARN
CLDN11	ENSG00000013297.6	395.23380	252.22770	0.64790	5.46510	4.33030	HepG2	PARN
PGM3	ENSG00000013375.11	2003.83760	2321.31810	-0.21220	2.37380	1.58400	HepG2	PARN
POLR3B	ENSG00000013503.5	206.68540	283.78050	-0.45730	2.45890	1.65630	HepG2	PARN
GPRC5A	ENSG00000013588.5	47.95880	101.89800	-1.08730	4.05350	3.05140	HepG2	PARN
MAMLD1	ENSG00000013619.9	3.39030	19.23060	-2.50390	2.17270	1.41400	HepG2	PARN
MDH1	ENSG00000014641.13	2398.60560	3295.52760	-0.45830	7.53700	6.25110	HepG2	PARN
DPEP1	ENSG00000015413.5	69.01990	115.65650	-0.74480	2.57110	1.75210	HepG2	PARN
CHDH	ENSG00000016391.6	1464.19230	1890.54400	-0.36870	5.43300	4.30110	HepG2	PARN
SRCIN1	ENSG00000017373.11	63.66670	109.92400	-0.78790	2.11440	1.36620	HepG2	PARN
WWTR1	ENSG00000018408.10	1806.46500	2302.12290	-0.34980	4.80100	3.72080	HepG2	PARN
AGPS	ENSG00000018510.8	2396.22250	3203.72190	-0.41900	8.48540	7.13190	HepG2	PARN
PHLDB1	ENSG00000019144.12	675.80850	477.48220	0.50110	5.23580	4.11950	HepG2	PARN
CYP24A1	ENSG00000019186.5	1287.34600	769.77400	0.74180	15.35560	13.63650	HepG2	PARN
CD74	ENSG00000019582.10	1979.86960	1391.73460	0.50840	9.87060	8.43700	HepG2	PARN
NCDN	ENSG00000020129.11	283.03270	185.82990	0.60690	3.24440	2.33420	HepG2	PARN
SAMD4A	ENSG00000020577.9	800.80510	1177.04740	-0.55560	8.87930	7.50420	HepG2	PARN
SERPINB1	ENSG00000021355.8	1611.95370	1381.28080	0.22270	2.18690	1.42610	HepG2	PARN
SPAST	ENSG00000021574.7	684.37340	869.20150	-0.34490	3.31050	2.39180	HepG2	PARN
NRXN3	ENSG00000021645.13	16.32390	1.05190	3.95580	3.63140	2.67470	HepG2	PARN
CPS1	ENSG00000021826.10	1200.56890	1429.41670	-0.25170	2.55980	1.74220	HepG2	PARN
C8B	ENSG00000021852.8	134.22340	255.98030	-0.93140	7.00000	5.75080	HepG2	PARN
FHL1	ENSG00000022267.12	40.23430	3.06730	3.71330	8.12310	6.79270	HepG2	PARN
RNF10	ENSG00000022840.11	1564.93330	1826.64880	-0.22310	2.34080	1.55480	HepG2	PARN
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

67 RBPs can affect the gene expression of PARN :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
PARN	ENSG00000140694.12	1462.47440	1182.32100	0.30670	4.00270	3.29640	HepG2	ACO1
PARN	ENSG00000140694.12	2311.31750	1392.29480	0.73120	7.75530	6.91220	HepG2	AKAP1
PARN	ENSG00000140694.12	737.24200	1140.35970	-0.62930	5.36810	4.15490	HepG2	BCLAF1
PARN	ENSG00000140694.12	1451.99290	1883.36740	-0.37530	3.39020	2.73480	HepG2	BOP1
PARN	ENSG00000140694.12	957.21330	1729.02450	-0.85300	12.78970	11.43210	HepG2	CPSF6
PARN	ENSG00000140694.12	1322.11730	1729.82860	-0.38780	7.30700	6.18710	HepG2	DAZAP1
PARN	ENSG00000140694.12	1394.81190	1963.43740	-0.49330	2.39190	1.48350	HepG2	DDX59
PARN	ENSG00000140694.12	906.68490	1145.80270	-0.33770	1.85860	1.34220	HepG2	DDX6
PARN	ENSG00000140694.12	831.79660	1141.87750	-0.45710	4.24130	3.03840	HepG2	DHX30
PARN	ENSG00000140694.12	905.90820	1183.91100	-0.38610	4.35240	3.48690	HepG2	DNAJC21
PARN	ENSG00000140694.12	1009.01670	1173.44060	-0.21780	2.21310	1.61710	HepG2	DNAJC2
PARN	ENSG00000140694.12	715.96570	1101.30730	-0.62130	5.57440	4.74990	HepG2	EIF2S1
PARN	ENSG00000140694.12	515.57730	1216.98670	-1.23910	17.56580	15.96640	HepG2	EIF4A3
PARN	ENSG00000140694.12	1050.77080	1634.71030	-0.63760	7.92400	6.57720	HepG2	EIF4G2
PARN	ENSG00000140694.12	1109.46100	2099.82220	-0.92040	28.85070	27.25490	HepG2	ETF1
PARN	ENSG00000140694.12	2041.79970	1595.81790	0.35540	2.36200	1.64640	HepG2	FIP1L1
PARN	ENSG00000140694.12	461.86420	1329.49270	-1.52530	34.39970	32.27560	HepG2	HNRNPC
PARN	ENSG00000140694.12	1335.76000	1804.80840	-0.43420	7.28410	6.19060	HepG2	HNRNPF
PARN	ENSG00000140694.12	1425.94020	1153.82020	0.30540	2.08540	1.47320	HepG2	HNRNPK
PARN	ENSG00000140694.12	1203.48760	1575.78040	-0.38880	7.06340	6.03180	HepG2	HNRNPL
PARN	ENSG00000140694.12	1068.42570	1870.42660	-0.80790	11.23130	10.06760	HepG2	HNRNPLL
PARN	ENSG00000140694.12	1395.80350	1777.21770	-0.34850	3.68330	2.85850	HepG2	IGF2BP1
PARN	ENSG00000140694.12	834.04820	1080.80830	-0.37390	5.08050	3.70690	HepG2	KIF1C
PARN	ENSG00000140694.12	860.11050	1228.58290	-0.51440	4.25520	3.44480	HepG2	MAGOH
PARN	ENSG00000140694.12	1961.93520	1235.41610	0.66720	6.68230	5.73450	HepG2	MATR3
PARN	ENSG00000140694.12	1645.71250	1291.82070	0.34920	3.42230	2.52430	HepG2	MSI2
PARN	ENSG00000140694.12	1376.87530	1907.64830	-0.47040	2.75430	1.78940	HepG2	MTPAP
PARN	ENSG00000140694.12	297.07710	1307.27680	-2.13770	91.25490	88.11980	HepG2	PARN
PARN	ENSG00000140694.12	963.41940	1177.96270	-0.29010	2.68970	1.96150	HepG2	PPIL4
PARN	ENSG00000140694.12	1674.57390	1395.87730	0.26250	2.85530	2.07210	HepG2	PRPF4
PARN	ENSG00000140694.12	571.18170	995.42200	-0.80140	8.32430	7.00760	HepG2	PRPF8
PARN	ENSG00000140694.12	1441.89040	1153.28120	0.32210	3.70170	3.08890	HepG2	PTBP1
PARN	ENSG00000140694.12	730.12900	1637.35650	-1.16510	26.08790	24.50910	HepG2	PUF60
PARN	ENSG00000140694.12	1473.95490	1736.84080	-0.23680	2.05740	1.47350	HepG2	PUM2
PARN	ENSG00000140694.12	1477.70640	1784.18130	-0.27190	2.51230	1.69160	HepG2	RBM15
PARN	ENSG00000140694.12	1409.66770	1133.57040	0.31440	2.61080	1.95310	HepG2	RBM25
PARN	ENSG00000140694.12	1502.67230	1944.27110	-0.37170	3.59870	2.83740	HepG2	RPLP0
PARN	ENSG00000140694.12	1210.87090	950.07260	0.34980	2.96720	2.33420	HepG2	RPS19
PARN	ENSG00000140694.12	602.03090	984.68250	-0.70980	6.13410	5.01240	HepG2	RRP9
PARN	ENSG00000140694.12	919.96800	1176.14780	-0.35440	3.67840	2.95480	HepG2	SAFB2
PARN	ENSG00000140694.12	1200.59250	953.57660	0.33220	2.26980	1.41470	HepG2	SERBP1
PARN	ENSG00000140694.12	1252.83240	1851.33790	-0.56340	6.59710	5.54570	HepG2	SF3B1
PARN	ENSG00000140694.12	1180.44730	1569.88380	-0.41130	7.38790	6.32580	HepG2	SLBP
PARN	ENSG00000140694.12	2007.60710	1253.27960	0.67970	17.13110	16.16740	HepG2	SRSF1
PARN	ENSG00000140694.12	1346.65260	1616.60090	-0.26360	3.05910	2.40450	HepG2	SRSF5
PARN	ENSG00000140694.12	1164.68240	1773.17620	-0.60640	13.07020	11.75110	HepG2	SRSF7
PARN	ENSG00000140694.12	863.28720	1019.61330	-0.24010	2.17930	1.67720	HepG2	SRSF9
PARN	ENSG00000140694.12	786.49890	1284.50950	-0.70770	6.55120	5.57780	HepG2	SUPV3L1
PARN	ENSG00000140694.12	1372.15290	1126.50810	0.28450	2.59160	2.04710	HepG2	TAF15
PARN	ENSG00000140694.12	1427.94760	1823.15510	-0.35250	2.91030	2.16920	HepG2	TARDBP
PARN	ENSG00000140694.12	1043.02280	1283.33000	-0.29910	2.59260	2.10580	HepG2	TIAL1
PARN	ENSG00000140694.12	865.94380	1294.78060	-0.58040	10.92070	9.91090	HepG2	TRIM56
PARN	ENSG00000140694.12	1312.94180	1521.73360	-0.21290	2.00990	1.51120	K562	AGGF1
PARN	ENSG00000140694.12	1076.42310	1583.41860	-0.55680	6.55830	5.52100	K562	AKAP8L
PARN	ENSG00000140694.12	1028.19080	1628.87440	-0.66380	8.62780	7.68500	K562	AQR
PARN	ENSG00000140694.12	1644.49960	2035.80410	-0.30800	4.16870	3.39100	K562	DDX47
PARN	ENSG00000140694.12	794.80520	981.95240	-0.30510	2.97730	1.71470	K562	EIF2S1
PARN	ENSG00000140694.12	618.50890	934.04680	-0.59470	6.25740	5.03290	K562	EIF4A3
PARN	ENSG00000140694.12	1803.11360	2158.55160	-0.25960	2.64290	1.72260	K562	EIF4G2
PARN	ENSG00000140694.12	1341.35720	1641.30770	-0.29120	2.16640	1.41370	K562	FIP1L1
PARN	ENSG00000140694.12	1446.79820	1814.24270	-0.32650	2.90260	2.12970	K562	GRSF1
PARN	ENSG00000140694.12	962.96740	1196.53140	-0.31330	2.59110	1.55080	K562	HNRNPA1
PARN	ENSG00000140694.12	403.58780	1081.11760	-1.42160	29.96120	28.08000	K562	HNRNPC
PARN	ENSG00000140694.12	1558.61490	1193.72460	0.38470	2.89980	1.63580	K562	HNRNPK
PARN	ENSG00000140694.12	855.73440	1256.14600	-0.55380	6.32440	5.03160	K562	MAGOH
PARN	ENSG00000140694.12	1442.63340	1660.16720	-0.20260	2.52120	1.80500	K562	NSUN2
PARN	ENSG00000140694.12	124.84160	656.65720	-2.39500	28.29970	23.95150	K562	PARN
PARN	ENSG00000140694.12	1349.00550	1863.13660	-0.46580	4.72280	3.60900	K562	PPIG
PARN	ENSG00000140694.12	1691.51280	2355.14240	-0.47750	5.42300	4.28240	K562	PUF60
PARN	ENSG00000140694.12	1106.86800	1530.05190	-0.46710	6.27430	5.40560	K562	RBM15
PARN	ENSG00000140694.12	1152.86440	911.56020	0.33870	2.10510	1.39680	K562	RPS19
PARN	ENSG00000140694.12	1401.93280	1638.09320	-0.22460	2.01410	1.31110	K562	SF3A3
PARN	ENSG00000140694.12	758.12060	1030.70260	-0.44310	4.55180	3.44410	K562	SF3B4
PARN	ENSG00000140694.12	1115.04810	1678.25570	-0.58990	13.88830	12.01050	K562	SRPK2
PARN	ENSG00000140694.12	901.33740	1129.97520	-0.32620	2.30530	1.36200	K562	SRSF5
PARN	ENSG00000140694.12	981.80300	1210.85280	-0.30250	1.97650	1.37080	K562	TARDBP
PARN	ENSG00000140694.12	795.50920	990.44440	-0.31620	2.14630	1.32880	K562	TRIM56
PARN	ENSG00000140694.12	1429.66710	1920.27100	-0.42560	3.84600	2.12880	K562	TRIP6
PARN	ENSG00000140694.12	813.98870	992.22130	-0.28570	2.11080	1.41010	K562	U2AF2
PARN	ENSG00000140694.12	1212.39130	1566.27920	-0.36950	5.89730	4.71150	K562	WDR43
PARN	ENSG00000140694.12	1365.58730	1834.99080	-0.42630	4.38960	3.26170	K562	ZC3H8
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for PARN is not available on ENCORE database.

12 RBPs can affect the splicing of PARN :

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	PARN	ENSG00000140694.12	chr16	-	14700340	14700383			14698002	14698083	14702137	14702176	-0.06900	0.00375	0.05938	excluded	K562	SF3B4
SE	PARN	ENSG00000140694.12	chr16	-	14711446	14711507			14704500	14704666	14720962	14720993	0.05200	0.00008	0.00157	included	HepG2	U2AF2
SE	PARN	ENSG00000140694.12	chr16	-	14721125	14721193			14721032	14721044	14722028	14722108	-0.14700	0.00044	0.00696	excluded	HepG2	U2AF2
SE	PARN	ENSG00000140694.12	chr16	-	14721125	14721193			14720962	14721044	14722028	14722108	-0.10800	0.00010	0.00173	excluded	K562	AQR
SE	PARN	ENSG00000140694.12	chr16	-	14680174	14680218			14678203	14678279	14687157	14687235	-0.12400	0.00002	0.00044	excluded	K562	AQR
SE	PARN	ENSG00000140694.12	chr16	-	14711446	14711507			14704500	14704666	14720962	14720993	0.05400	0.00010	0.00822	included	HepG2	SFPQ
SE	PARN	ENSG00000140694.12	chr16	-	14711446	14711507			14704500	14704666	14720962	14720993	0.05200	0.00013	0.02734	included	HepG2	HNRNPUL1
SE	PARN	ENSG00000140694.12	chr16	-	14711446	14711507			14704500	14704666	14720962	14720993	0.05700	0.00018	0.02866	included	HepG2	RBFOX2
SE	PARN	ENSG00000140694.12	chr16	-	14647921	14648008			14645877	14645952	14649510	14649566	0.15100	0.00004	0.02741	included	HepG2	DROSHA
SE	PARN	ENSG00000140694.12	chr16	-	14647014	14647107			14645877	14645952	14647921	14648008	0.07900	0.00150	0.02682	included	K562	HNRNPC
SE	PARN	ENSG00000140694.12	chr16	-	14711446	14711507			14704500	14704666	14720962	14720993	-0.06000	0.00381	0.05614	excluded	K562	HNRNPC
A3SS	PARN	ENSG00000140694.12	chr16	-	14720962	14721065			14720962	14721044	14721125	14721193	0.11200	0.00001	0.00188	longer	HepG2	RBM22
A3SS	PARN	ENSG00000140694.12	chr16	-	14530524	14530750			14530524	14530629	14540744	14540938	0.08800	0.00000	0.00000	longer	K562	AQR
A3SS	PARN	ENSG00000140694.12	chr16	-	14721125	14721229			14721125	14721193	14722028	14722108	0.05300	0.00050	0.00376	longer	K562	AQR
A3SS	PARN	ENSG00000140694.12	chr16	-	14540813	14540995			14540813	14540938	14576494	14576684	0.06400	0.00001	0.00013	longer	K562	AQR
MXE	PARN	ENSG00000140694.12	chr16	-	14698002	14698083	14700340	14700383	14693760	14693817	14702137	14702176	-0.26000	0.00011	0.00125	2included	K562	AQR
MXE	PARN	ENSG00000140694.12	chr16	-	14680174	14680218	14687157	14687235	14678203	14678279	14693760	14693817	-0.08000	0.01199	0.07330	2included	K562	AQR
MXE	PARN	ENSG00000140694.12	chr16	-	14693760	14693817	14698002	14698083	14687157	14687235	14700340	14700383	-0.15900	0.00000	0.00002	2included	HepG2	SFPQ
MXE	PARN	ENSG00000140694.12	chr16	-	14693760	14693817	14698002	14698083	14687157	14687235	14700340	14700383	-0.21600	0.00000	0.00000	2included	HepG2	U2AF2
MXE	PARN	ENSG00000140694.12	chr16	-	14687157	14687235	14693760	14693817	14680174	14680218	14698002	14698083	-0.15200	0.00030	0.00291	2included	HepG2	U2AF2
MXE	PARN	ENSG00000140694.12	chr16	-	14693760	14693817	14698002	14698083	14687157	14687235	14700340	14700383	-0.09500	0.00078	0.02879	2included	HepG2	RBFOX2
MXE	PARN	ENSG00000140694.12	chr16	-	14693760	14693817	14698002	14698083	14687157	14687235	14700340	14700383	-0.08900	0.00118	0.02128	2included	HepG2	HNRNPUL1
MXE	PARN	ENSG00000140694.12	chr16	-	14678605	14678648	14680174	14680218	14678203	14678279	14687157	14687235	-0.13800	0.00115	0.03580	2included	K562	SBDS
MXE	PARN	ENSG00000140694.12	chr16	-	14680174	14680218	14687157	14687235	14678605	14678648	14693760	14693817	-0.07600	0.00492	0.08327	2included	K562	PPIL4
MXE	PARN	ENSG00000140694.12	chr16	-	14680174	14680218	14687157	14687235	14678605	14678648	14693760	14693817	-0.11700	0.00228	0.05631	2included	HepG2	TIAL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

PARN

General Information

Functions

Localization

Domains (AlphaFold: PARN)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for PARN is not avaliable on ENCORE database.

37 proteins are bound to PARN RNA:

eCLIP assay for PARN is not avaliable on ENCORE database.

Diffrential Expression

4,335 differentially expressed genes after Knockdown/Knockout PARN protein :

67 RBPs can affect the gene expression of PARN :

The Knockdown/knockout RNA-Seq assay for PARN is not available on ENCORE database.

12 RBPs can affect the splicing of PARN :

The Knockdown/knockout RNA-Seq assay for PARN is not avaliable on ENCORE database.