BRCA1

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	BRCA1	ENSG00000012048.21	28.48	30.46	29.47	ENCSR000AEF
HepG2	BRCA1	ENSG00000012048.21	25.41	29.03	27.22	ENCSR985KAT
K562	BRCA1	ENSG00000012048.21	54.02	51.88	52.95	ENCSR000AEO

GeneName	Cell_Line	Method	Sample_reps	Control_reps	KD%	Status	Project
BRCA1	Ribo-STAMP-293T	shRNA	BGRSLV02-57,BGRSLV02-58	BGRSLV02-1,BGRSLV02-2		NotSatisfied	ENCORE2
BRCA1	Ribo-STAMP-293T	shRNA	BGRSLV07-7,BGRSLV07-8	BGRSLV07-1,BGRSLV07-2		NotSatisfied	ENCORE2
BRCA1	Ribo-STAMP-293T	shRNA	BGRSLV09-3,BGRSLV09-4	BGRSLV09-1,BGRSLV09-2		NotSatisfied	ENCORE2
BRCA1	Ribo-STAMP-293T	shRNA	BGRSLV09-5,BGRSLV09-6	BGRSLV09-1,BGRSLV09-2		NotSatisfied	ENCORE2
BRCA1	Ribo-STAMP-293T	shRNA	BGRSDLV02-9,BGRSDLV02-10	BGRSDLV02-1,BGRSDLV02-2		Submitted	ENCORE2
BRCA1	Ribo-STAMP-293T	shRNA	BRCA1-BGRSDLV02-11dox,BRCA1-BGRSDLV02-12dox	BRCA1-BGRSDLV02-9,BRCA1-BGRSDLV02-10	,	Submitted	ENCORE2

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr17	41215958	41216026	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.90823	5.40008	K562	SF3B4
chr17	41203052	41203115	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.40339	3.49905	HepG2	PPIG
chr17	41256232	41256279	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	4.37710	3.71570	HepG2	BCLAF1
chr17	41234569	41234593	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.84616	3.66349	K562	LIN28B
chr17	41196397	41196458	-	3'-UTR,intron-Distal	4.31063	3.87930	K562	UPF1
chr17	41196322	41196464	-	3'-UTR,intron-Distal	4.90127	7.06234	K562	PUM2
chr17	41203053	41203081	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.81979	9.08030	K562	AQR
chr17	41203029	41203088	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.88994	3.70131	HepG2	PRPF8
chr17	41197758	41197817	-	3'-UTR,CDS,intron-Distal	4.76703	7.21258	K562	LIN28B
chr17	41256159	41256213	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	3.30660	4.08171	K562	YBX3
chr17	41258471	41258551	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	4.06836	6.81238	K562	ZNF622
chr17	41249219	41249312	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	3.91962	6.15234	K562	PRPF8
chr17	41222939	41223018	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.06616	5.77418	K562	UCHL5
chr17	41246486	41246569	-	3'-UTR,5'-UTR,CDS,intron-Distal	3.84424	7.43456	K562	SAFB2
chr17	41246104	41246176	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	3.08876	5.51957	K562	SAFB2
chr17	41245320	41245395	-	5'-UTR,CDS,intron-Distal	3.61095	6.16263	K562	SAFB2
chr17	41277288	41277347	-	5'-UTR,intron-Distal,intron-Proximal	4.10543	7.37356	K562	DDX3X
chr17	41242964	41243032	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.01306	5.77244	K562	UCHL5
chr17	41246041	41246099	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.27269	5.37891	K562	SAFB2
chr17	41244122	41244179	-	5'-UTR,CDS,intron-Distal	3.11275	3.73364	K562	SAFB2
chr17	41242960	41242976	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.79018	3.06853	K562	LIN28B
chr17	41245519	41245621	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.00446	7.00245	K562	SAFB2
chr17	41276031	41276068	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.08034	3.02457	HepG2	BCLAF1
chr17	41242960	41242998	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.24130	3.89826	HepG2	BCLAF1
chr17	41245251	41245303	-	5'-UTR,CDS,intron-Distal	3.09087	3.24890	K562	SAFB2
chr17	41244733	41244794	-	5'-UTR,CDS,intron-Distal	3.95655	3.25175	K562	YBX3
chr17	41243908	41243946	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.94687	3.46958	K562	YBX3
chr17	41243793	41243833	-	5'-UTR,CDS,intron-Distal	3.84647	3.43228	K562	SAFB2
chr17	41277248	41277363	-	5'-UTR,intron-Distal,intron-Proximal	4.74892	5.32122	HepG2	NCBP2
chr17	41267767	41267821	-	CDS,intron-Distal,intron-Proximal	4.15773	4.90655	K562	U2AF2
chr17	41267744	41267796	-	CDS,intron-Distal	4.06810	3.86355	HepG2	PPIG
chr17	41267749	41267794	-	CDS,intron-Distal	3.52892	4.40383	K562	UCHL5
chr17	41226912	41226961	-	intron-Distal	5.16524	6.40067	K562	PTBP1
chr17	41226909	41227018	-	intron-Distal	4.22335	4.03269	HepG2	PTBP1
chr17	41228694	41228828	-	intron-Distal,intron-Proximal	4.31521	10.35163	K562	KHSRP
chr17	41233081	41233200	-	intron-Distal	3.11945	7.14496	K562	KHSRP
chr17	41277079	41277168	-	intron-Distal	4.45283	4.46189	K562	GTF2F1
chr17	41258933	41259067	-	intron-Distal	3.92378	3.71397	K562	KHSRP
chr17	41215658	41215867	-	intron-Distal,intron-Proximal	3.50232	4.09242	HepG2	QKI
chr17	41215759	41215835	-	intron-Distal,intron-Proximal	4.71591	5.50285	K562	PRPF8
chr17	41203031	41203053	-	intron-Distal,intron-Proximal	5.94475	11.65826	K562	AQR
chr17	41276973	41277174	-	intron-Distal	3.20782	4.30514	K562	FUS
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Diffrential Expression

The Knockdown/knockout assay for BRCA1 is not available on ENCORE database.
162 RBPs can affect the levels of BRCA1.

The Knockdown/knockout RNA-Seq assay for BRCA1 is not available on ENCORE database.

162 RBPs can affect the gene expression of BRCA1 :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
BRCA1	ENSG00000012048.15	753.53580	886.64320	-0.23470	1.95570	1.42810	HepG2	ACO1
BRCA1	ENSG00000012048.15	989.40570	775.38450	0.35160	2.34650	1.42590	HepG2	ADAR
BRCA1	ENSG00000012048.15	116.98870	206.73140	-0.82140	3.58700	2.40690	HepG2	AKAP8
BRCA1	ENSG00000012048.15	608.81010	890.91880	-0.54930	6.75060	5.60790	HepG2	AKAP8L
BRCA1	ENSG00000012048.15	155.61770	425.38620	-1.45080	15.02770	13.34800	HepG2	ASCC1
BRCA1	ENSG00000012048.15	567.43360	1383.96880	-1.28630	40.17160	38.08830	HepG2	AUH
BRCA1	ENSG00000012048.15	557.87830	1003.31590	-0.84680	8.05850	6.40780	HepG2	BCCIP
BRCA1	ENSG00000012048.15	393.00100	871.80680	-1.14950	14.03330	12.23930	HepG2	BCLAF1
BRCA1	ENSG00000012048.15	130.05850	1597.76020	-3.61880	140.14890	137.45790	HepG2	BOP1
BRCA1	ENSG00000012048.15	467.82250	1360.30250	-1.53990	42.45120	40.19300	HepG2	CALR
BRCA1	ENSG00000012048.15	247.36790	404.14210	-0.70820	4.53540	3.55860	HepG2	CIRBP
BRCA1	ENSG00000012048.15	290.08060	886.58260	-1.61180	32.80560	31.09100	HepG2	CKAP4
BRCA1	ENSG00000012048.15	81.13050	152.98760	-0.91510	2.53680	1.80590	HepG2	CNOT7
BRCA1	ENSG00000012048.15	573.90510	1466.84400	-1.35380	26.85260	24.99220	HepG2	CPSF6
BRCA1	ENSG00000012048.15	629.44220	1272.67470	-1.01570	24.62090	23.09920	HepG2	CELF1
BRCA1	ENSG00000012048.15	779.04170	1368.41380	-0.81270	21.96560	20.23810	HepG2	DAZAP1
BRCA1	ENSG00000012048.15	540.40950	833.93760	-0.62590	3.33530	2.32830	HepG2	DDX24
BRCA1	ENSG00000012048.15	154.22240	492.49480	-1.67510	20.34870	18.81970	HepG2	DDX3X
BRCA1	ENSG00000012048.15	480.79430	986.46600	-1.03680	11.57230	10.12070	HepG2	DDX55
BRCA1	ENSG00000012048.15	707.30280	1665.70480	-1.23570	11.34060	9.43760	HepG2	DDX59
BRCA1	ENSG00000012048.15	598.00360	1004.60620	-0.74840	7.82990	6.22010	HepG2	DDX5
BRCA1	ENSG00000012048.15	114.37520	422.99960	-1.88690	20.40710	18.93850	HepG2	DDX6
BRCA1	ENSG00000012048.15	459.56630	753.04920	-0.71250	5.55060	4.19040	HepG2	DHX30
BRCA1	ENSG00000012048.15	675.19630	848.31150	-0.32930	2.93850	2.24200	HepG2	DKC1
BRCA1	ENSG00000012048.15	472.71500	780.75740	-0.72390	10.06760	8.79230	HepG2	DNAJC21
BRCA1	ENSG00000012048.15	452.89530	773.90240	-0.77300	14.01900	12.66840	HepG2	DNAJC2
BRCA1	ENSG00000012048.15	381.22180	784.82390	-1.04170	5.91830	4.30910	HepG2	AGO1
BRCA1	ENSG00000012048.15	63.66940	406.70290	-2.67530	35.42810	33.46320	HepG2	EIF2S1
BRCA1	ENSG00000012048.15	360.51230	644.33330	-0.83780	7.07440	5.68900	HepG2	EIF3D
BRCA1	ENSG00000012048.15	873.58130	1350.04490	-0.62800	11.56840	10.09080	HepG2	EIF4G1
BRCA1	ENSG00000012048.15	627.30400	1293.25290	-1.04380	16.98970	15.10170	HepG2	EIF4G2
BRCA1	ENSG00000012048.15	797.77290	1588.92910	-0.99400	26.91690	25.36890	HepG2	ETF1
BRCA1	ENSG00000012048.15	591.19620	866.52610	-0.55160	5.55830	4.37160	HepG2	EWSR1
BRCA1	ENSG00000012048.15	573.44140	1144.54740	-0.99710	4.36710	3.41660	HepG2	FIP1L1
BRCA1	ENSG00000012048.15	621.42070	1469.33100	-1.24150	7.52580	5.85790	HepG2	FTO
BRCA1	ENSG00000012048.15	823.37500	453.41910	0.86060	8.98640	7.80420	HepG2	FXR1
BRCA1	ENSG00000012048.15	288.21710	420.66140	-0.54550	2.98780	2.29800	HepG2	G3BP1
BRCA1	ENSG00000012048.15	421.86330	573.68800	-0.44350	2.84530	1.93420	HepG2	GEMIN5
BRCA1	ENSG00000012048.15	608.63420	1662.81780	-1.45000	26.67090	24.92070	HepG2	GPKOW
BRCA1	ENSG00000012048.15	547.10000	846.57060	-0.62980	8.27670	6.69730	HepG2	HDGF
BRCA1	ENSG00000012048.15	474.35220	788.23770	-0.73270	7.71280	6.71610	HepG2	HNRNPA1
BRCA1	ENSG00000012048.15	722.38350	1257.62300	-0.79990	16.70420	14.80190	HepG2	HNRNPA2B1
BRCA1	ENSG00000012048.15	528.22590	876.78180	-0.73110	7.89370	6.76930	HepG2	HNRNPC
BRCA1	ENSG00000012048.15	217.01040	132.52060	0.71140	3.10860	1.50670	HepG2	HNRNPD
BRCA1	ENSG00000012048.15	609.53450	1148.22630	-0.91360	20.46050	18.75620	HepG2	HNRNPF
BRCA1	ENSG00000012048.15	750.90830	1246.51290	-0.73120	17.11270	15.56500	HepG2	HNRNPL
BRCA1	ENSG00000012048.15	537.84140	1586.85440	-1.56090	33.77900	31.97330	HepG2	HNRNPLL
BRCA1	ENSG00000012048.15	589.02960	1130.68050	-0.94080	16.67860	15.07060	HepG2	IGF2BP1
BRCA1	ENSG00000012048.15	92.74980	427.61040	-2.20490	28.87200	26.97210	HepG2	IGF2BP2
BRCA1	ENSG00000012048.15	738.36460	889.67920	-0.26900	2.89770	2.14880	HepG2	ILF2
BRCA1	ENSG00000012048.15	302.78450	145.82410	1.05400	7.01780	5.02970	HepG2	KHDRBS1
BRCA1	ENSG00000012048.15	573.25470	810.58520	-0.49980	5.21510	3.82450	HepG2	KIF1C
BRCA1	ENSG00000012048.15	871.69740	1798.43540	-1.04480	9.85450	8.29000	HepG2	LARP4
BRCA1	ENSG00000012048.15	712.63170	926.61120	-0.37880	2.77570	1.63850	HepG2	LARP7
BRCA1	ENSG00000012048.15	723.87820	972.94210	-0.42660	3.30410	1.97670	HepG2	LIN28B
BRCA1	ENSG00000012048.15	1019.38180	453.57700	1.16820	16.21780	14.69230	HepG2	MAGOH
BRCA1	ENSG00000012048.15	803.92770	456.13070	0.81750	7.26190	6.27630	HepG2	MATR3
BRCA1	ENSG00000012048.15	406.41880	674.33490	-0.73050	4.28020	2.98530	HepG2	METAP2
BRCA1	ENSG00000012048.15	1002.04860	1618.30680	-0.69150	5.10240	3.75960	HepG2	MTPAP
BRCA1	ENSG00000012048.15	343.11680	466.88730	-0.44440	2.18420	1.61950	HepG2	NCBP2
BRCA1	ENSG00000012048.15	637.85280	837.84470	-0.39350	2.80540	1.37740	HepG2	NIP7
BRCA1	ENSG00000012048.15	294.94180	905.82250	-1.61880	15.87740	13.16970	HepG2	NONO
BRCA1	ENSG00000012048.15	1102.18610	1407.02390	-0.35230	2.75230	2.00630	HepG2	NSUN2
BRCA1	ENSG00000012048.15	163.74350	415.84980	-1.34460	13.38790	11.82680	HepG2	PABPC4
BRCA1	ENSG00000012048.15	713.42380	862.10880	-0.27310	2.23680	1.46780	HepG2	PARN
BRCA1	ENSG00000012048.15	544.68030	430.16490	0.34040	2.45540	1.87590	HepG2	PCBP1
BRCA1	ENSG00000012048.15	343.94990	1026.99540	-1.57820	20.02770	17.62750	HepG2	PCBP2
BRCA1	ENSG00000012048.15	585.49130	889.09150	-0.60270	4.40490	2.30080	HepG2	PHF6
BRCA1	ENSG00000012048.15	541.16410	776.84590	-0.52160	5.79250	4.75810	HepG2	PPIL4
BRCA1	ENSG00000012048.15	216.02370	760.99110	-1.81670	30.02980	27.82700	HepG2	PRPF8
BRCA1	ENSG00000012048.15	581.77370	437.71540	0.41040	3.23670	2.65420	HepG2	PTBP1
BRCA1	ENSG00000012048.15	387.63950	1295.30320	-1.74050	45.83570	43.80210	HepG2	PUF60
BRCA1	ENSG00000012048.15	828.96810	1375.02920	-0.73010	18.70020	17.43750	HepG2	PUM1
BRCA1	ENSG00000012048.15	824.84320	1374.02010	-0.73620	12.18230	10.83300	HepG2	PUM2
BRCA1	ENSG00000012048.15	609.53470	991.06760	-0.70130	3.86410	3.03500	HepG2	RAVER1
BRCA1	ENSG00000012048.15	864.16680	1236.67530	-0.51710	6.47620	5.23180	HepG2	RBM15
BRCA1	ENSG00000012048.15	247.94970	1328.06160	-2.42120	95.80250	93.61880	HepG2	RBM22
BRCA1	ENSG00000012048.15	205.34930	430.22950	-1.06700	10.90950	9.63180	HepG2	RBM25
BRCA1	ENSG00000012048.15	727.07320	1117.34170	-0.61990	6.11400	4.62960	HepG2	RBM27
BRCA1	ENSG00000012048.15	345.02240	147.77570	1.22320	8.74920	6.13160	HepG2	RBM47
BRCA1	ENSG00000012048.15	594.40120	907.33070	-0.61020	4.63000	3.25330	HepG2	RCC2
BRCA1	ENSG00000012048.15	1235.35810	487.12980	1.34250	38.10200	36.60060	HepG2	NELFE
BRCA1	ENSG00000012048.15	941.74250	453.70510	1.05350	22.13600	20.68070	HepG2	RECQL
BRCA1	ENSG00000012048.15	141.59930	1236.84050	-3.12680	103.73060	101.13230	HepG2	RPLP0
BRCA1	ENSG00000012048.15	247.35870	973.54290	-1.97660	27.76910	25.08200	HepG2	RPS10
BRCA1	ENSG00000012048.15	197.67650	626.99200	-1.66530	29.52320	27.87390	HepG2	RPS19
BRCA1	ENSG00000012048.15	500.30090	1030.48720	-1.04250	14.85780	13.10810	HepG2	RPS2
BRCA1	ENSG00000012048.15	95.31900	153.66930	-0.68900	2.27980	1.55200	HepG2	RPS3A
BRCA1	ENSG00000012048.15	134.31740	752.77900	-2.48660	45.26130	42.88680	HepG2	RRP9
BRCA1	ENSG00000012048.15	466.84700	775.64220	-0.73240	11.81120	10.62340	HepG2	SAFB2
BRCA1	ENSG00000012048.15	430.18160	629.24090	-0.54870	4.02660	2.89550	HepG2	SERBP1
BRCA1	ENSG00000012048.15	569.11290	1084.35890	-0.93010	9.61130	8.29740	HepG2	SF3A3
BRCA1	ENSG00000012048.15	584.49840	1570.69310	-1.42610	32.11690	30.03620	HepG2	SF3B1
BRCA1	ENSG00000012048.15	749.73630	1242.00970	-0.72820	16.49810	15.04580	HepG2	SLBP
BRCA1	ENSG00000012048.15	577.34010	966.97290	-0.74410	2.96210	1.30600	HepG2	SLTM
BRCA1	ENSG00000012048.15	576.58490	1010.55030	-0.80950	6.87470	5.31120	HepG2	SMNDC1
BRCA1	ENSG00000012048.15	500.05330	1747.66410	-1.80530	26.36840	24.03750	HepG2	SNRNP70
BRCA1	ENSG00000012048.15	246.20060	1500.01600	-2.60710	119.67520	117.62840	HepG2	SRFBP1
BRCA1	ENSG00000012048.15	655.41050	475.66370	0.46240	4.31960	3.76080	HepG2	SRSF1
BRCA1	ENSG00000012048.15	660.07500	1690.01230	-1.35630	20.51620	17.69110	HepG2	SRSF3
BRCA1	ENSG00000012048.15	729.64880	1278.93250	-0.80970	17.86260	16.46760	HepG2	SRSF5
BRCA1	ENSG00000012048.15	319.95870	1128.07580	-1.81790	63.77250	61.48140	HepG2	SRSF7
BRCA1	ENSG00000012048.15	281.77230	386.98190	-0.45770	3.24120	2.65330	HepG2	SRSF9
BRCA1	ENSG00000012048.15	985.79000	1302.40270	-0.40180	5.51330	4.83790	HepG2	SSB
BRCA1	ENSG00000012048.15	618.72470	926.17830	-0.58200	3.18730	1.88960	HepG2	SUB1
BRCA1	ENSG00000012048.15	1148.33480	1454.49060	-0.34100	4.75410	3.97810	HepG2	SUCLG1
BRCA1	ENSG00000012048.15	132.12880	227.12170	-0.78150	3.35170	1.87950	HepG2	SUGP2
BRCA1	ENSG00000012048.15	433.88040	773.26700	-0.83370	4.35750	3.19210	HepG2	SUPT6H
BRCA1	ENSG00000012048.15	195.93700	982.01530	-2.32540	47.73080	45.61790	HepG2	SUPV3L1
BRCA1	ENSG00000012048.15	963.63790	427.55840	1.17230	25.20950	23.74640	HepG2	TAF15
BRCA1	ENSG00000012048.15	335.05140	1546.59660	-2.20660	64.73250	62.10380	HepG2	TARDBP
BRCA1	ENSG00000012048.15	496.31140	220.28060	1.17180	3.69620	2.47050	HepG2	TBRG4
BRCA1	ENSG00000012048.15	219.71860	658.21260	-1.58290	21.59720	19.42590	HepG2	TFIP11
BRCA1	ENSG00000012048.15	188.38960	846.27480	-2.16740	58.32970	56.59630	HepG2	TIAL1
BRCA1	ENSG00000012048.15	391.92550	853.89250	-1.12350	12.76430	11.67890	HepG2	TRIM56
BRCA1	ENSG00000012048.15	948.85930	1265.46900	-0.41540	3.17780	2.23600	HepG2	TUFM
BRCA1	ENSG00000012048.15	557.38810	979.36060	-0.81320	4.33200	3.55480	HepG2	U2AF1
BRCA1	ENSG00000012048.15	432.75070	1689.52070	-1.96500	3.06940	2.02830	HepG2	U2AF2
BRCA1	ENSG00000012048.15	906.33700	1339.48730	-0.56360	4.59770	3.50000	HepG2	UBE2L3
BRCA1	ENSG00000012048.15	402.64280	580.10910	-0.52680	3.52360	2.67100	HepG2	UCHL5
BRCA1	ENSG00000012048.15	292.15870	961.65900	-1.71880	54.81870	52.59470	HepG2	UPF1
BRCA1	ENSG00000012048.15	610.42330	899.23470	-0.55890	3.08240	2.02360	HepG2	UPF2
BRCA1	ENSG00000012048.15	635.71040	988.46260	-0.63680	9.69380	7.87700	HepG2	UTP18
BRCA1	ENSG00000012048.15	805.10950	1089.91900	-0.43700	2.35590	1.37830	HepG2	XRCC6
BRCA1	ENSG00000012048.15	738.67320	966.68620	-0.38810	2.39840	1.71920	HepG2	XRN2
BRCA1	ENSG00000012048.15	122.68370	1057.64300	-3.10780	152.21560	149.94380	HepG2	ZNF622
BRCA1	ENSG00000012048.15	629.47040	990.17320	-0.65350	4.79570	3.04120	HepG2	ZRANB2
BRCA1	ENSG00000012048.15	1404.81730	3917.45240	-1.47950	17.20780	15.91440	K562	AGGF1
BRCA1	ENSG00000012048.15	1314.42800	1631.84470	-0.31210	2.88180	1.34550	K562	AKAP1
BRCA1	ENSG00000012048.15	2705.82050	4304.13010	-0.66970	6.28430	4.65700	K562	AKAP8
BRCA1	ENSG00000012048.15	1365.25790	4076.14960	-1.57800	16.86520	14.99860	K562	AKAP8L
BRCA1	ENSG00000012048.15	2505.67650	3818.19100	-0.60770	9.15010	8.18370	K562	AQR
BRCA1	ENSG00000012048.15	2272.21950	4276.60270	-0.91240	8.15280	6.45710	K562	ATP5C1
BRCA1	ENSG00000012048.15	3109.68560	4004.82160	-0.36500	6.27450	4.57390	K562	CPEB4
BRCA1	ENSG00000012048.15	1553.76200	1855.47370	-0.25600	2.38570	1.41410	K562	CSTF2
BRCA1	ENSG00000012048.15	1782.29510	2144.63350	-0.26700	3.24110	1.79250	K562	DDX27
BRCA1	ENSG00000012048.15	1041.26050	1653.29620	-0.66700	8.57360	6.64980	K562	DDX3X
BRCA1	ENSG00000012048.15	3387.50580	4144.71720	-0.29110	4.20060	3.41960	K562	DDX47
BRCA1	ENSG00000012048.15	1210.51570	1676.16390	-0.46950	5.62900	3.51800	K562	DDX6
BRCA1	ENSG00000012048.15	2773.46030	4387.08970	-0.66160	5.09450	3.85410	K562	DKC1
BRCA1	ENSG00000012048.15	1649.56640	2166.76480	-0.39350	3.32150	2.31650	K562	EFTUD2
BRCA1	ENSG00000012048.15	1848.14200	2329.21620	-0.33380	4.37760	3.38600	K562	EIF3G
BRCA1	ENSG00000012048.15	1261.99080	1555.33740	-0.30150	2.66510	1.54020	K562	EIF4B
BRCA1	ENSG00000012048.15	1135.22750	1507.60090	-0.40930	3.56780	2.07400	K562	EWSR1
BRCA1	ENSG00000012048.15	2051.62740	3460.31400	-0.75410	12.27250	10.37010	K562	FIP1L1
BRCA1	ENSG00000012048.15	2211.65430	1796.18920	0.30010	3.56560	2.89240	K562	FXR1
BRCA1	ENSG00000012048.15	1692.63620	2430.44730	-0.52190	7.13800	4.71720	K562	G3BP1
BRCA1	ENSG00000012048.15	2578.42280	1825.98510	0.49770	3.30130	2.51570	K562	G3BP2
BRCA1	ENSG00000012048.15	1874.03000	2748.43320	-0.55250	7.68980	6.36130	K562	GPKOW
BRCA1	ENSG00000012048.15	2308.33880	4181.24900	-0.85710	19.72080	17.61100	K562	GRSF1
BRCA1	ENSG00000012048.15	1446.50210	3908.68480	-1.43410	4.94350	3.16610	K562	HNRNPA2B1
BRCA1	ENSG00000012048.15	2203.83600	2846.01220	-0.36890	2.57160	1.67780	K562	HNRNPM
BRCA1	ENSG00000012048.15	2411.74450	2947.60580	-0.28950	3.52160	2.51420	K562	HNRNPU
BRCA1	ENSG00000012048.15	1863.73040	2542.05240	-0.44780	3.43180	2.24520	K562	IGF2BP2
BRCA1	ENSG00000012048.15	2079.58170	2585.65570	-0.31420	2.74960	1.56290	K562	IGF2BP3
BRCA1	ENSG00000012048.15	1965.33560	4326.29460	-1.13840	7.39380	5.88320	K562	KIF1C
BRCA1	ENSG00000012048.15	1748.44030	2346.67540	-0.42450	2.70740	1.78680	K562	KRR1
BRCA1	ENSG00000012048.15	2219.99500	4140.93820	-0.89940	5.22860	3.58970	K562	MAK16
BRCA1	ENSG00000012048.15	2753.51290	4846.47550	-0.81570	6.87720	5.31710	K562	MBNL1
BRCA1	ENSG00000012048.15	2149.01330	2682.75430	-0.32000	2.85120	1.95980	K562	METAP2
BRCA1	ENSG00000012048.15	1348.73740	3396.98600	-1.33260	9.14900	7.17860	K562	NAA15
BRCA1	ENSG00000012048.15	1344.55070	1724.83440	-0.35930	3.65580	2.22310	K562	NCBP2
BRCA1	ENSG00000012048.15	1032.71120	2134.53550	-1.04750	17.47890	14.19190	K562	NONO
BRCA1	ENSG00000012048.15	2982.77680	3373.30470	-0.17750	2.98690	2.21530	K562	NSUN2
BRCA1	ENSG00000012048.15	841.90160	3421.26940	-2.02280	7.05180	5.22800	K562	PABPN1
BRCA1	ENSG00000012048.15	3706.10610	2958.59800	0.32490	2.38370	1.61310	K562	PCBP3
BRCA1	ENSG00000012048.15	2946.06710	2269.36200	0.37640	4.80720	3.75040	K562	POLR2G
BRCA1	ENSG00000012048.15	2352.61820	3927.93110	-0.73950	7.99950	6.44070	K562	PPIG
BRCA1	ENSG00000012048.15	1734.38100	4069.74660	-1.23050	3.74730	1.96240	K562	PPP1R8
BRCA1	ENSG00000012048.15	1447.69840	2108.50710	-0.54250	5.85170	4.75910	K562	PRPF8
BRCA1	ENSG00000012048.15	1540.43570	1971.96980	-0.35630	3.20870	2.22270	K562	PSIP1
BRCA1	ENSG00000012048.15	869.74590	4043.40400	-2.21690	26.04610	24.37570	K562	PUS1
BRCA1	ENSG00000012048.15	1307.12480	3938.87420	-1.59140	17.48150	15.96960	K562	RBM15
BRCA1	ENSG00000012048.15	1119.25420	1734.08520	-0.63160	2.58260	1.30710	K562	RBM25
BRCA1	ENSG00000012048.15	1497.70330	1798.92380	-0.26440	2.19030	1.31220	K562	RCC2
BRCA1	ENSG00000012048.15	1943.56600	2293.93700	-0.23910	3.32380	1.59050	K562	RPS10
BRCA1	ENSG00000012048.15	1455.25520	2147.88030	-0.56160	4.98590	3.88750	K562	RPS19
BRCA1	ENSG00000012048.15	2632.85450	2090.54130	0.33270	2.83770	1.37400	K562	SDAD1
BRCA1	ENSG00000012048.15	1204.23780	3130.14960	-1.37810	3.89460	2.39210	K562	SF1
BRCA1	ENSG00000012048.15	1337.59180	1900.71920	-0.50690	2.20850	1.44600	K562	SF3B4
BRCA1	ENSG00000012048.15	1551.21320	3592.74590	-1.21170	3.80610	2.28140	K562	SNRNP200
BRCA1	ENSG00000012048.15	1324.20500	1705.35690	-0.36490	3.19360	2.07210	K562	SRFBP1
BRCA1	ENSG00000012048.15	1863.02480	2544.66060	-0.44980	5.88430	4.86120	K562	SRSF1
BRCA1	ENSG00000012048.15	1673.20600	2403.20990	-0.52230	6.16400	4.48910	K562	SRSF5
BRCA1	ENSG00000012048.15	2003.65880	2484.24650	-0.31020	3.10770	2.23200	K562	TIA1
BRCA1	ENSG00000012048.15	1345.83480	2014.76390	-0.58210	7.59610	5.84740	K562	TRIM56
BRCA1	ENSG00000012048.15	1802.71590	4098.59690	-1.18500	6.42270	4.25850	K562	UTP18
BRCA1	ENSG00000012048.15	2477.89800	3060.54650	-0.30470	3.06680	2.14700	K562	WDR3
BRCA1	ENSG00000012048.15	2718.18670	3182.56610	-0.22750	3.47180	2.53220	K562	WDR43
BRCA1	ENSG00000012048.15	3631.81310	4301.59280	-0.24420	2.06860	1.33370	K562	ZC3H8
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for BRCA1 is not available on ENCORE database.

13 RBPs can affect the splicing of BRCA1 :

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	BRCA1	ENSG00000012048.15	chr17	-	41247862	41247939			41243451	41246877	41249260	41249306	-0.10500	0.00416	0.06540	excluded	K562	SRSF1
SE	BRCA1	ENSG00000012048.15	chr17	-	41228504	41228631			41226347	41226538	41234420	41234592	-0.06800	0.00004	0.00252	excluded	K562	AKAP8L
SE	BRCA1	ENSG00000012048.15	chr17	-	41199659	41199720			41196312	41197819	41201137	41201211	-0.05400	0.00936	0.07702	excluded	K562	AQR
SE	BRCA1	ENSG00000012048.15	chr17	-	41247862	41247939			41243451	41246877	41251791	41251894	0.54200	0.00049	0.02472	included	HepG2	MATR3
SE	BRCA1	ENSG00000012048.15	chr17	-	41276033	41276132			41267742	41267796	41277287	41277500	-0.09700	0.00086	0.03057	excluded	K562	UTP18
SE	BRCA1	ENSG00000012048.15	chr17	-	41228504	41228631			41226347	41226538	41234420	41234592	-0.14300	0.00000	0.00001	excluded	K562	UTP18
SE	BRCA1	ENSG00000012048.15	chr17	-	41247862	41247939			41243451	41246877	41251791	41251894	-0.26800	0.00014	0.00381	excluded	K562	U2AF2
SE	BRCA1	ENSG00000012048.15	chr17	-	41247862	41247939			41243451	41246877	41251791	41251897	-0.21200	0.00077	0.03085	excluded	K562	HNRNPU
SE	BRCA1	ENSG00000012048.15	chr17	-	41247862	41247939			41243451	41246877	41249260	41249306	-0.14500	0.00057	0.01762	excluded	K562	RBM15
SE	BRCA1	ENSG00000012048.15	chr17	-	41219624	41219712			41215890	41215968	41222944	41223255	-0.14200	0.00000	0.00000	excluded	K562	HNRNPC
A3SS	BRCA1	ENSG00000012048.15	chr17	-	41234420	41234639			41234420	41234592	41242960	41243049	0.05800	0.00023	0.00187	longer	K562	AQR
A3SS	BRCA1	ENSG00000012048.15	chr17	-	41203079	41203225			41203079	41203134	41209068	41209152	0.07000	0.00000	0.00001	longer	K562	AQR
A5SS	BRCA1	ENSG00000012048.15	chr17	-	41277287	41277387			41277293	41277387	41276033	41276132	0.35300	0.00030	0.04193	longer	K562	RBM22
A5SS	BRCA1	ENSG00000012048.15	chr17	-	41243451	41246877			41246760	41246877	41242960	41243049	-0.41500	0.00001	0.00067	shorter	K562	SRSF1
MXE	BRCA1	ENSG00000012048.15	chr17	-	41267742	41267796	41276033	41276132	41258472	41258550	41277293	41277468	0.10400	0.00182	0.02763	1included	K562	DROSHA
MXE	BRCA1	ENSG00000012048.15	chr17	-	41201137	41201211	41203079	41203134	41199659	41199720	41209068	41209152	-0.15900	0.00014	0.00434	2included	K562	DROSHA
MXE	BRCA1	ENSG00000012048.15	chr17	-	41246760	41246912	41247862	41247939	41242960	41243049	41251791	41251897	-0.40200	0.00262	0.04067	2included	K562	SRSF1
MXE	BRCA1	ENSG00000012048.15	chr17	-	41199659	41199720	41201137	41201211	41196312	41197819	41203079	41203134	-0.16600	0.00673	0.08266	2included	K562	SRSF1
MXE	BRCA1	ENSG00000012048.15	chr17	-	41246760	41246877	41247862	41247939	41242960	41243049	41251791	41251897	-0.19400	0.00014	0.00387	2included	K562	SRSF1
MXE	BRCA1	ENSG00000012048.15	chr17	-	41246760	41246877	41247862	41247939	41242960	41243049	41249260	41249306	-0.36300	0.00000	0.00012	2included	K562	SRSF1
MXE	BRCA1	ENSG00000012048.15	chr17	-	41201137	41201211	41203079	41203185	41199659	41199720	41209068	41209152	0.17500	0.00004	0.00047	1included	K562	AQR
MXE	BRCA1	ENSG00000012048.15	chr17	-	41199659	41199720	41203079	41203185	41196312	41197819	41209068	41209152	0.10300	0.00001	0.00011	1included	K562	AQR
MXE	BRCA1	ENSG00000012048.15	chr17	-	41201137	41201211	41203079	41203134	41197645	41197819	41209068	41209152	-0.08300	0.00023	0.00248	2included	K562	AQR
MXE	BRCA1	ENSG00000012048.15	chr17	-	41267742	41267796	41276033	41276132	41258472	41258550	41277293	41277468	-0.13400	0.01197	0.07319	2included	K562	AQR
MXE	BRCA1	ENSG00000012048.15	chr17	-	41267742	41267796	41276033	41276132	41258472	41258550	41277293	41277468	-0.17600	0.00147	0.03572	2included	K562	TARDBP
MXE	BRCA1	ENSG00000012048.15	chr17	-	41226347	41226538	41228504	41228631	41222944	41223255	41234420	41234592	-0.14300	0.00148	0.04215	2included	K562	SBDS

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

BRCA1

General Information

Functions

Localization

Domains (AlphaFold: BRCA1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for BRCA1 is not avaliable on ENCORE database.

20 proteins are bound to BRCA1 RNA:

eCLIP assay for BRCA1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for BRCA1 is not available on ENCORE database.

162 RBPs can affect the gene expression of BRCA1 :

The Knockdown/knockout RNA-Seq assay for BRCA1 is not available on ENCORE database.

13 RBPs can affect the splicing of BRCA1 :

The Knockdown/knockout RNA-Seq assay for BRCA1 is not avaliable on ENCORE database.