WT1

General Information

Gene Name       : WT1
Gene ID             : ENSG00000184937.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: WT1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878WT1ENSG00000184937.130.010.010.01ENCSR000AEF
HepG2WT1ENSG00000184937.130.200.120.16ENCSR985KAT
K562WT1ENSG00000184937.1323.7122.7523.23ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for WT1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • WT1 RNA is bound by 7 proteins.  







eCLIP assay for WT1 is not avaliable on ENCORE database.





7 proteins are bound to WT1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr113240940832409514-3'-UTR,intron-Distal5.4892925.31939K562PUM2
chr113240979432409835-3'-UTR,intron-Distal4.137086.12308K562PUM2
chr113240947932409588-3'-UTR,intron-Distal3.067273.01386K562DDX6
chr113240945332409564-3'-UTR,intron-Distal3.4479610.00571K562KHSRP
chr113240972932409771-3'-UTR,intron-Distal5.571799.99898K562PUM2
chr113240949632409572-3'-UTR,intron-Distal3.766069.44690K562TARDBP
chr113243803232438092-5'-UTR,CDS,intron-Distal,intron-Proximal3.822433.00996K562BUD13
chr113245190432451994-intron-Distal3.704904.57279K562PTBP1
chr113244926832449322-intron-Distal3.851863.59342K562CSTF2T
chr113243256632432636-intron-Distal4.447355.71021K562TARDBP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for WT1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for WT1 is not available on ENCORE database.

  • 44 RBPs can affect the levels of WT1.  








The Knockdown/knockout RNA-Seq assay for WT1 is not available on ENCORE database.





44 RBPs can affect the gene expression of WT1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
WT1ENSG00000184937.818.475901.565203.561103.242202.51570HepG2PUM2
WT1ENSG00000184937.826.294701.758503.902305.198904.25350HepG2SF3B1
WT1ENSG00000184937.811.071901.402302.981002.086701.46580HepG2UPF1
WT1ENSG00000184937.8940.51530536.059600.8110010.226207.97340K562AARS
WT1ENSG00000184937.8366.34070633.37770-0.7899010.244209.24250K562AGGF1
WT1ENSG00000184937.8488.13310918.62780-0.912208.784507.83440K562AQR
WT1ENSG00000184937.8703.221401104.57140-0.651403.788002.51010K562CNOT7
WT1ENSG00000184937.8602.30200798.71620-0.407203.220302.37290K562CPSF6
WT1ENSG00000184937.81229.937701565.75880-0.348303.043502.02240K562CELF1
WT1ENSG00000184937.81316.619101091.593700.270302.761302.11090K562DDX47
WT1ENSG00000184937.81345.47850851.314400.6603011.8941010.55620K562EIF2S2
WT1ENSG00000184937.8536.47300407.036300.398202.740101.94700K562EIF3G
WT1ENSG00000184937.8307.18830407.20300-0.406602.201701.46620K562EIF4A3
WT1ENSG00000184937.8655.38400861.07840-0.393802.815901.95900K562FIP1L1
WT1ENSG00000184937.8712.42810509.293300.484103.227601.99340K562FKBP4
WT1ENSG00000184937.8638.41310423.472900.592106.203205.35090K562FXR1
WT1ENSG00000184937.8694.91100862.04570-0.310902.597101.49320K562GLRX3
WT1ENSG00000184937.8811.529601134.47180-0.483304.520803.55760K562GRSF1
WT1ENSG00000184937.8460.72130710.38350-0.624706.383204.79400K562HNRNPA1
WT1ENSG00000184937.8423.13800586.47520-0.470903.302802.65870K562HNRNPC
WT1ENSG00000184937.8637.16740786.72480-0.304202.308201.49060K562HNRNPU
WT1ENSG00000184937.8524.29970699.44940-0.415803.071502.19940K562KIF1C
WT1ENSG00000184937.8936.825901357.56930-0.535205.002903.48890K562MSI2
WT1ENSG00000184937.8622.86390906.31310-0.541106.119004.95580K562MTPAP
WT1ENSG00000184937.8709.872401007.08240-0.504606.054805.01080K562NSUN2
WT1ENSG00000184937.8338.14690586.76650-0.795103.377702.25070K562PABPN1
WT1ENSG00000184937.8571.13760918.84860-0.686006.203704.95460K562PCBP3
WT1ENSG00000184937.8429.82750704.77630-0.713407.782606.46350K562POLR2G
WT1ENSG00000184937.81099.10810501.096501.1331023.2107021.36160K562PTBP1
WT1ENSG00000184937.8443.29060653.66520-0.560304.286403.63270K562PUS1
WT1ENSG00000184937.8497.58240636.84030-0.356002.591802.01540K562RBM15
WT1ENSG00000184937.8805.580801075.82390-0.417303.683101.81860K562RBM17
WT1ENSG00000184937.8692.26450480.550300.526504.375303.28620K562RBM22
WT1ENSG00000184937.8717.55260505.688600.504703.884502.56310K562NELFE
WT1ENSG00000184937.8360.09280501.94640-0.479202.462001.69280K562RPS19
WT1ENSG00000184937.8423.15840286.991600.560102.834701.81940K562RPS3
WT1ENSG00000184937.8307.39230536.70160-0.804003.016301.74230K562SF1
WT1ENSG00000184937.8839.48130993.60370-0.243202.021901.31710K562SF3A3
WT1ENSG00000184937.8850.900601017.95670-0.258602.237601.38630K562SRPK2
WT1ENSG00000184937.8415.23130737.20310-0.828103.577901.88450K562SUPT6H
WT1ENSG00000184937.8542.79210392.696900.466903.616802.69670K562U2AF2
WT1ENSG00000184937.8294.06940504.96460-0.780006.276704.67380K562UCHL5
WT1ENSG00000184937.8752.309801067.82390-0.505305.243304.28910K562UPF1
WT1ENSG00000184937.8389.49760662.67760-0.766703.793102.20320K562UTP18
WT1ENSG00000184937.8565.51700913.71450-0.692208.709607.11550K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for WT1 is not available on ENCORE database.





5 RBPs can affect the splicing of WT1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEWT1ENSG00000184937.8chr11-324380353243808632421493324215903243912232439200-0.480000.000000.00004excludedK562SRSF1
SEWT1ENSG00000184937.8chr11-324380353243808632421493324215903243912232439200-0.348000.000900.01924excludedK562SF3B4
SEWT1ENSG00000184937.8chr11-324380353243808632421493324215903243912232439200-0.204000.002730.08061excludedK562HNRNPU
SEWT1ENSG00000184937.8chr11-324380353243808632421493324215903243912232439200-0.258000.000450.02176excludedK562SF3B1
A3SSWT1ENSG00000184937.8chr11-3241058732410753324105873241072532413517324136100.086000.001360.00914longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for WT1 is not avaliable on ENCORE database.