TTC8

General Information

Gene Name       : TTC8
Gene ID             : ENSG00000165533.18
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TTC8)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TTC8ENSG00000165533.182.251.952.10ENCSR000AEF
HepG2TTC8ENSG00000165533.1810.2911.7211.00ENCSR985KAT
K562TTC8ENSG00000165533.186.718.877.79ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TTC8 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TTC8 RNA is bound by 2 proteins.  







eCLIP assay for TTC8 is not avaliable on ENCORE database.





2 proteins are bound to TTC8 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr148930658989306607+intron-Distal6.2119416.85572K562TROVE2
chr148930656389306589+intron-Distal6.2173916.85572K562TROVE2
chr148930643989306498+intron-Distal3.960703.06853K562LIN28B
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TTC8 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TTC8 is not available on ENCORE database.

  • 36 RBPs can affect the levels of TTC8.  








The Knockdown/knockout RNA-Seq assay for TTC8 is not available on ENCORE database.





36 RBPs can affect the gene expression of TTC8 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TTC8ENSG00000165533.14659.70050398.059400.728705.174504.47570HepG2AKAP1
TTC8ENSG00000165533.14128.05010238.29060-0.896003.113702.01130HepG2AKAP8
TTC8ENSG00000165533.14507.50460329.361900.623604.160903.20630HepG2ASCC1
TTC8ENSG00000165533.14302.50120135.503801.158506.538705.36230HepG2CNOT7
TTC8ENSG00000165533.14571.66240381.313400.584103.825103.10100HepG2DDX3X
TTC8ENSG00000165533.14191.77470327.55010-0.772304.149803.40490HepG2DDX6
TTC8ENSG00000165533.14279.75940202.582300.465602.386201.74980HepG2DKC1
TTC8ENSG00000165533.14280.07140177.703500.656203.385102.15500HepG2EFTUD2
TTC8ENSG00000165533.14198.63240314.88780-0.664703.432102.77570HepG2EIF2S1
TTC8ENSG00000165533.14220.70580338.81250-0.618402.628401.95670HepG2EIF4B
TTC8ENSG00000165533.14384.76310268.750900.517602.573901.51920HepG2ESF1
TTC8ENSG00000165533.14287.67380206.923400.475202.352101.58290HepG2EWSR1
TTC8ENSG00000165533.14224.64400154.070900.543902.263001.46000HepG2GEMIN5
TTC8ENSG00000165533.14185.34630329.79100-0.831305.253104.31380HepG2HNRNPK
TTC8ENSG00000165533.14248.21630327.86530-0.401502.592201.93890HepG2HNRNPL
TTC8ENSG00000165533.14185.69990253.49780-0.449002.035601.33690HepG2MSI2
TTC8ENSG00000165533.14291.87450215.673500.436402.452801.86340HepG2PUS1
TTC8ENSG00000165533.14388.85600295.490000.396002.221201.44240HepG2RBM15
TTC8ENSG00000165533.14237.85220325.35380-0.451902.231801.60900HepG2RPLP0
TTC8ENSG00000165533.14232.04840168.378400.462601.827901.31820HepG2RPS19
TTC8ENSG00000165533.14173.19180264.82180-0.612702.686901.89760HepG2RPS2
TTC8ENSG00000165533.14256.32840136.035300.913904.709403.66590HepG2RPS3A
TTC8ENSG00000165533.14381.84000246.383300.632003.849903.02900HepG2SF3B1
TTC8ENSG00000165533.14558.18580274.146201.025706.983205.73540HepG2SNRNP70
TTC8ENSG00000165533.14468.41200367.186400.351202.436101.94870HepG2SSB
TTC8ENSG00000165533.14225.20490352.22490-0.645303.064702.18580HepG2UBE2L3
TTC8ENSG00000165533.1467.42330136.71370-1.019803.688602.81320HepG2UCHL5
TTC8ENSG00000165533.14348.31570246.551500.498403.185602.58410K562AGGF1
TTC8ENSG00000165533.14168.43370287.17630-0.769804.264503.56600K562AQR
TTC8ENSG00000165533.14373.32050269.185500.471703.123402.14970K562ATP5C1
TTC8ENSG00000165533.14137.51770209.29220-0.605902.663401.89330K562CPSF6
TTC8ENSG00000165533.14388.40770272.257400.512503.096402.21940K562KIF1C
TTC8ENSG00000165533.14255.44670171.211900.577103.089102.24060K562POLR2G
TTC8ENSG00000165533.14669.31400494.288500.437203.625502.39480K562PUM1
TTC8ENSG00000165533.14151.65390227.03320-0.582102.770201.92960K562RBM22
TTC8ENSG00000165533.14131.13670232.06000-0.823404.545503.64320K562SRSF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TTC8 is not available on ENCORE database.





17 RBPs can affect the splicing of TTC8 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETTC8ENSG00000165533.14chr14+893413698934145389338673893387968934363789344295-0.229000.000360.00859excludedHepG2U2AF1
SETTC8ENSG00000165533.14chr14+893413698934145389338673893387968934363789344332-0.171000.002030.05408excludedK562AKAP8L
SETTC8ENSG00000165533.14chr14+893413698934145389338673893387968934363789344332-0.421000.000000.00002excludedHepG2U2AF2
SETTC8ENSG00000165533.14chr14+893077688930785889307380893075408931014989310194-0.596000.000010.02479excludedK562EWSR1
SETTC8ENSG00000165533.14chr14+8934136989341453893386738933879689343637893442950.219000.001230.06043includedHepG2PTBP1
SETTC8ENSG00000165533.14chr14+893413698934145389338673893387968934363789344332-0.270000.000000.00019excludedHepG2FTO
SETTC8ENSG00000165533.14chr14+893077688930785889307380893075408931014989310194-0.391000.005910.09189excludedK562U2AF1
SETTC8ENSG00000165533.14chr14+893077688930785889307380893075408931014989310194-0.665000.000000.00762excludedK562DDX6
SETTC8ENSG00000165533.14chr14+8934136989341453893386738933879689343637893443320.222000.002140.04626includedHepG2SRSF1
SETTC8ENSG00000165533.14chr14+893077688930785889307380893075408931014989310194-0.531000.000000.00073excludedHepG2TIAL1
SETTC8ENSG00000165533.14chr14+8934136989341453893386738933879689343637893443320.224000.000510.02726includedHepG2SF3B4
SETTC8ENSG00000165533.14chr14+893413698934145389338673893387968934363789344332-0.237000.000360.01567excludedK562UTP18
SETTC8ENSG00000165533.14chr14+893413698934145389338673893387968934363789344295-0.246000.000550.01704excludedK562RBM15
SETTC8ENSG00000165533.14chr14+893413698934145389338673893387968934363789344295-0.292000.000000.00011excludedK562AGGF1
SETTC8ENSG00000165533.14chr14+893077688930785889307380893075408931014989310194-0.404000.000470.08891excludedHepG2FUS
A5SSTTC8ENSG00000165533.14chr14+893073808930785889307380893075408931014989310194-0.563000.000030.00949shorterHepG2TIAL1
A5SSTTC8ENSG00000165533.14chr14+893073808930785889307380893075408931014989310194-0.556000.000290.08681shorterHepG2HNRNPL
RITTC8ENSG00000165533.14chr14+8930738089307858893073808930754089307768893078580.248000.005150.05062includedHepG2HNRNPK
MXETTC8ENSG00000165533.14chr14+8930776889307901893101498931019489307380893075408931931489319400-0.416000.000750.081412includedHepG2FUS
MXETTC8ENSG00000165533.14chr14+8930776889307901893101498931019489307380893075408931931489319400-0.400000.000120.007232includedHepG2TIAL1
MXETTC8ENSG00000165533.14chr14+89307768893079018931014989310194893073808930754089319314893194000.406000.000350.068071includedHepG2SUB1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TTC8 is not avaliable on ENCORE database.