TIAM2

General Information

Gene Name       : TIAM2
Gene ID             : ENSG00000146426.18
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TIAM2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TIAM2ENSG00000146426.181.271.551.41ENCSR000AEF
HepG2TIAM2ENSG00000146426.182.114.693.40ENCSR985KAT
K562TIAM2ENSG00000146426.183.172.923.04ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TIAM2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TIAM2 RNA is bound by 17 proteins.  







eCLIP assay for TIAM2 is not avaliable on ENCORE database.





17 proteins are bound to TIAM2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr6155154537155154608+3'-UTR,5'-UTR,intron-Proximal3.9433613.79507K562PUM2
chr6155154238155154317+5'-UTR,CDS3.343633.63681K562RBM15
chr6155154435155154538+3'-UTR,5'-UTR,CDS3.150599.17110HepG2BCLAF1
chr6155154013155154052+5'-UTR,CDS3.067923.34735K562UCHL5
chr6155154060155154208+5'-UTR,CDS3.319874.38249K562RBM15
chr6155154157155154194+5'-UTR,CDS4.865775.92514HepG2HLTF
chr6155154307155154351+5'-UTR,CDS3.259216.91872HepG2BCLAF1
chr6155174529155174569+intron-Distal4.170313.46884K562DGCR8
chr6155161372155161424+intron-Distal3.926323.50357HepG2QKI
chr6155178613155178838+intron-Distal3.748833.84589K562HNRNPL
chr6155154559155154661+3'-UTR,intron-Distal,intron-Proximal3.788744.97883K562CPSF6
chr6155174360155174433+intron-Distal3.558344.00440HepG2ILF3
chr6155174531155174625+intron-Distal3.969853.31709K562ILF3
chr6155154757155154799+3'-UTR,intron-Distal3.827373.19904K562TIA1
chr6155191126155191191+intron-Distal4.922948.65382HepG2HNRNPC
chr6155244792155244842+intron-Distal4.556583.70058HepG2XPO5
chr6155174547155174585+intron-Distal4.8042714.51851HepG2ILF3
chr6155178750155178836+intron-Distal3.860287.07327HepG2AGGF1
chr6155155263155155316+intron-Distal3.348064.99588HepG2CSTF2
chr6155213695155213755+intron-Distal4.122806.11515K562PTBP1
chr6155155190155155297+3'-UTR,intron-Distal4.276454.75311K562CSTF2T
chr6155213694155213761+intron-Distal3.214826.20894HepG2PTBP1
chr6155174532155174547+intron-Distal5.4882711.99732HepG2ILF3
chr6155155244155155263+intron-Distal3.940523.69311HepG2CSTF2
chr6155154560155154601+3'-UTR,intron-Proximal3.930564.93978HepG2BCLAF1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TIAM2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TIAM2 is not available on ENCORE database.

  • 41 RBPs can affect the levels of TIAM2.  








The Knockdown/knockout RNA-Seq assay for TIAM2 is not available on ENCORE database.





41 RBPs can affect the gene expression of TIAM2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TIAM2ENSG00000146426.13166.4750095.558800.800703.227202.25530HepG2BCLAF1
TIAM2ENSG00000146426.1391.36060226.72100-1.311308.744707.75230HepG2BOP1
TIAM2ENSG00000146426.1368.53610146.39890-1.095005.945505.03790HepG2CKAP4
TIAM2ENSG00000146426.1359.14590154.66500-1.386805.994604.86700HepG2CNOT7
TIAM2ENSG00000146426.13216.65490108.100401.002904.972003.97210HepG2DDX55
TIAM2ENSG00000146426.13123.64470183.10790-0.566502.062701.35160HepG2EIF4G2
TIAM2ENSG00000146426.13298.74620158.848600.911204.676703.69680HepG2FIP1L1
TIAM2ENSG00000146426.1365.22020140.86870-1.111004.467803.60140HepG2HNRNPC
TIAM2ENSG00000146426.13185.37760109.584400.758303.402502.35720HepG2HNRNPM
TIAM2ENSG00000146426.1388.19090147.26740-0.739702.680601.51260HepG2KHDRBS1
TIAM2ENSG00000146426.13100.36420154.00320-0.617701.840701.32080HepG2MATR3
TIAM2ENSG00000146426.13223.85650157.634900.505901.852901.32790HepG2NCBP2
TIAM2ENSG00000146426.1392.76900138.51570-0.578302.044001.30710HepG2PARN
TIAM2ENSG00000146426.13214.31230143.368700.579902.720202.11750HepG2PCBP1
TIAM2ENSG00000146426.13177.5617083.436601.089505.335604.24970HepG2PRPF8
TIAM2ENSG00000146426.13280.89560145.866800.945307.380806.57210HepG2PTBP1
TIAM2ENSG00000146426.13311.47750194.542400.678904.395803.56020HepG2PUM2
TIAM2ENSG00000146426.13478.08090149.163701.6803030.0836028.44980HepG2PUS1
TIAM2ENSG00000146426.13221.90640158.012000.489801.865101.33720HepG2QKI
TIAM2ENSG00000146426.13549.55960133.697702.0392019.1661017.47550HepG2RAVER1
TIAM2ENSG00000146426.13218.47490143.392900.607402.607601.95010HepG2RBM25
TIAM2ENSG00000146426.13167.64920102.184800.714202.989202.35430HepG2RPS19
TIAM2ENSG00000146426.13188.5822082.540501.191906.035304.92220HepG2RRP9
TIAM2ENSG00000146426.1374.60040124.62130-0.740302.747402.10440HepG2SAFB2
TIAM2ENSG00000146426.13205.78760145.330700.501702.353901.75440HepG2SMN1
TIAM2ENSG00000146426.1378.14970136.16920-0.801102.869601.89430HepG2SMNDC1
TIAM2ENSG00000146426.13312.92900215.444100.538403.507402.96390HepG2SRFBP1
TIAM2ENSG00000146426.13349.61790107.625601.699709.031707.92480HepG2SUPV3L1
TIAM2ENSG00000146426.1380.87200135.98020-0.749702.971502.45570HepG2TIAL1
TIAM2ENSG00000146426.13434.64420135.871701.6775018.2331016.56780HepG2U2AF1
TIAM2ENSG00000146426.13126.71810180.58900-0.511102.155701.52660HepG2UPF1
TIAM2ENSG00000146426.13115.27790174.35130-0.596902.442401.87220HepG2UTP3
TIAM2ENSG00000146426.13258.40960198.613100.379601.868901.39540HepG2ZNF622
TIAM2ENSG00000146426.1327.0020059.77460-1.146502.674202.11330K562AGGF1
TIAM2ENSG00000146426.13165.8696081.747201.020704.038803.35590K562AQR
TIAM2ENSG00000146426.1390.2831037.166001.280404.549503.49680K562EIF4A3
TIAM2ENSG00000146426.13102.5286053.275200.944402.932201.98960K562FTO
TIAM2ENSG00000146426.1321.5194065.58530-1.607704.183502.81070K562IGF2BP2
TIAM2ENSG00000146426.1330.4505066.96450-1.136903.198202.49010K562PTBP1
TIAM2ENSG00000146426.1329.3093060.10160-1.036002.379201.82230K562RBM15
TIAM2ENSG00000146426.1332.1901065.64790-1.028102.340201.68290K562SRSF1
TIAM2ENSG00000146426.1384.8395043.730900.956002.666901.59800K562U2AF1
TIAM2ENSG00000146426.1397.6389045.142901.112904.158903.17650K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TIAM2 is not available on ENCORE database.





3 RBPs can affect the splicing of TIAM2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETIAM2ENSG00000146426.13chr6+155181871155182132155154478155154543155265249155265340-0.642000.000990.05759excludedHepG2AKAP1
SETIAM2ENSG00000146426.13chr6+1551818711551821321551544781551545431552288631552300000.357000.002470.08715includedHepG2SFPQ
A5SSTIAM2ENSG00000146426.13chr6+155154478155154717155154478155154543155181871155182132-0.247000.000150.01783shorterHepG2U2AF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TIAM2 is not avaliable on ENCORE database.