NFE4

General Information

Gene Name       : NFE4
Gene ID             : ENSG00000230257.2
Essential Gene : No

Functions

Localization

Domains (AlphaFold: NFE4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878NFE4ENSG00000230257.20.000.000.00ENCSR000AEF
HepG2NFE4ENSG00000230257.20.000.000.00ENCSR985KAT
K562NFE4ENSG00000230257.242.0939.7140.90ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for NFE4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • NFE4 RNA is bound by 2 proteins.  







eCLIP assay for NFE4 is not avaliable on ENCORE database.





2 proteins are bound to NFE4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr7102618400102618495+intron-Distal3.686683.84914K562SLTM
chr7102620802102620913+intron-Distal4.617105.81661K562SAFB2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for NFE4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for NFE4 is not available on ENCORE database.

  • 56 RBPs can affect the levels of NFE4.  








The Knockdown/knockout RNA-Seq assay for NFE4 is not available on ENCORE database.





56 RBPs can affect the gene expression of NFE4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
NFE4ENSG00000230257.1213.28610731.07840-1.7772041.5274039.38000K562AGGF1
NFE4ENSG00000230257.1605.60740803.30560-0.407602.995101.96050K562AKAP8
NFE4ENSG00000230257.1202.27780760.71060-1.9110038.3864035.47970K562AKAP8L
NFE4ENSG00000230257.1257.16380650.93850-1.3398017.1715015.87370K562AQR
NFE4ENSG00000230257.1411.70640798.15030-0.9550015.9685013.57560K562ATP5C1
NFE4ENSG00000230257.1717.39510935.90900-0.383602.869001.87840K562CELF1
NFE4ENSG00000230257.1588.18660857.75430-0.544304.740302.79720K562DDX19B
NFE4ENSG00000230257.1443.28230634.17980-0.516705.283504.42370K562DDX47
NFE4ENSG00000230257.1369.28980818.63930-1.1485022.9947020.12860K562DKC1
NFE4ENSG00000230257.11161.33860406.668601.5138044.9053042.72780K562EIF2S2
NFE4ENSG00000230257.1260.53770421.64890-0.694503.256802.39580K562EIF3G
NFE4ENSG00000230257.1118.82190215.56380-0.859305.020003.17950K562EWSR1
NFE4ENSG00000230257.1188.67280389.67170-1.046409.015807.39010K562FIP1L1
NFE4ENSG00000230257.11018.07410565.736500.847504.816403.68640K562FMR1
NFE4ENSG00000230257.1246.99490372.73390-0.593702.862501.49890K562FUS
NFE4ENSG00000230257.1254.01940419.42200-0.723505.879803.68770K562G3BP1
NFE4ENSG00000230257.1319.34230442.09890-0.469303.296202.04820K562GLRX3
NFE4ENSG00000230257.1288.59910400.19810-0.471602.922101.81710K562HNRNPA1
NFE4ENSG00000230257.1226.30550948.77100-2.067802.835301.59750K562HNRNPA2B1
NFE4ENSG00000230257.1233.75070438.09070-0.906307.237105.16340K562HNRNPK
NFE4ENSG00000230257.1742.09070573.162600.372602.732501.68630K562HNRNPL
NFE4ENSG00000230257.1607.80210320.499800.923208.534906.74940K562HNRNPM
NFE4ENSG00000230257.11647.10860528.327201.6403040.4905037.96180K562HSPD1
NFE4ENSG00000230257.1340.75690807.33770-1.2444019.0314016.09440K562KIF1C
NFE4ENSG00000230257.1464.29920772.79350-0.735005.230903.59050K562MAK16
NFE4ENSG00000230257.1561.15040904.41750-0.688603.356302.33830K562MBNL1
NFE4ENSG00000230257.1276.74970633.92820-1.1957011.140608.89950K562NAA15
NFE4ENSG00000230257.1120.07290224.29250-0.901503.786101.64970K562PABPC4
NFE4ENSG00000230257.1120.49710830.76580-2.785403.802602.59020K562PABPN1
NFE4ENSG00000230257.1205.71770410.18060-0.995608.861507.08250K562PCBP2
NFE4ENSG00000230257.1568.45630442.339000.361802.038001.33790K562PPIG
NFE4ENSG00000230257.1180.39690264.16620-0.550302.408301.70640K562PRPF8
NFE4ENSG00000230257.1524.27940830.61450-0.663805.930804.74130K562PUF60
NFE4ENSG00000230257.11174.00860883.373600.410204.231102.89120K562PUM1
NFE4ENSG00000230257.11188.96640865.648900.457805.938404.51360K562PUM2
NFE4ENSG00000230257.1176.62200754.48490-2.0948038.5267036.45320K562PUS1
NFE4ENSG00000230257.1190.79810735.07490-1.9458044.3240041.85210K562RBM15
NFE4ENSG00000230257.1324.31970429.42320-0.405002.269601.51300K562RBM22
NFE4ENSG00000230257.164.03200201.26910-1.652309.999607.31390K562RBM25
NFE4ENSG00000230257.1568.65680418.687100.441602.728901.36320K562RBM34
NFE4ENSG00000230257.1294.16370136.543701.107206.830505.16850K562RPS3
NFE4ENSG00000230257.1160.39820251.14670-0.646903.202502.03820K562SAFB
NFE4ENSG00000230257.1127.99500226.00200-0.820203.631801.82260K562SERBP1
NFE4ENSG00000230257.1188.92480760.25180-2.008702.518401.39140K562SF1
NFE4ENSG00000230257.165.25540220.60970-1.7573011.398809.59440K562SF3B4
NFE4ENSG00000230257.1198.33080872.33250-2.137002.863001.60890K562SNRNP200
NFE4ENSG00000230257.1338.56040522.11910-0.625006.424805.06780K562SRPK2
NFE4ENSG00000230257.1205.13290131.776900.638402.497601.50540K562SRSF4
NFE4ENSG00000230257.1572.97930428.698600.418402.521201.74450K562TIA1
NFE4ENSG00000230257.1184.90790303.06870-0.712803.848202.73650K562TIAL1
NFE4ENSG00000230257.1221.29620321.97160-0.541002.709701.77470K562TRIM56
NFE4ENSG00000230257.171.00700205.69760-1.534508.577806.48330K562U2AF1
NFE4ENSG00000230257.159.87980212.35480-1.8263011.8384010.16080K562U2AF2
NFE4ENSG00000230257.1302.29380764.89950-1.339304.808602.94110K562UTP18
NFE4ENSG00000230257.1363.12120468.53990-0.367702.084701.32680K562WDR3
NFE4ENSG00000230257.1328.72550487.25180-0.567805.576404.41820K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for NFE4 is not available on ENCORE database.





11 RBPs can affect the splicing of NFE4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SENFE4ENSG00000230257.1chr7+1026265571026267331026139681026142181026284791026286790.164000.004520.06993includedK562SRSF1
SENFE4ENSG00000230257.1chr7+1026187611026189671026139681026142181026265571026267330.621000.004940.07331includedK562SF3B4
SENFE4ENSG00000230257.1chr7+1026188271026189671026139681026142181026284791026286790.217000.000290.00429includedK562AQR
SENFE4ENSG00000230257.1chr7+1026265571026267331026139681026142181026284791026286790.523000.000000.00010includedK562U2AF1
SENFE4ENSG00000230257.1chr7+102618827102618967102613968102614218102628479102628600-0.232000.000000.00008excludedK562HNRNPL
SENFE4ENSG00000230257.1chr7+1026265571026267331026139681026142181026284791026286790.391000.000100.00288includedK562U2AF2
SENFE4ENSG00000230257.1chr7+102626557102626733102613968102614218102628479102628679-0.212000.000270.03681excludedK562CPSF6
SENFE4ENSG00000230257.1chr7+102618827102618967102613968102614218102628479102628679-0.182000.002160.08018excludedK562HNRNPK
SENFE4ENSG00000230257.1chr7+1026188271026189671026139681026142181026284791026286790.280000.000010.00041includedK562HNRNPC
SENFE4ENSG00000230257.1chr7+102626557102626733102618761102618967102628479102628679-0.232000.000220.00525excludedK562HNRNPC
A3SSNFE4ENSG00000230257.1chr7+1026187611026189671026188271026189671026139681026142180.142000.000650.03442longerK562PUS1
MXENFE4ENSG00000230257.1chr7+1026164581026166771026188271026189671026139681026142181026284791026286790.149000.000640.056111includedK562HNRNPL
MXENFE4ENSG00000230257.1chr7+102618761102618967102626557102626733102613968102614218102628479102628679-0.225000.001140.082092includedK562HNRNPL
MXENFE4ENSG00000230257.1chr7+102618827102618967102626557102626733102613968102614218102628479102628679-0.268000.000010.002602includedK562HNRNPL
MXENFE4ENSG00000230257.1chr7+102618761102618967102626557102626733102613968102614218102628479102628679-0.483000.000420.010102includedK562U2AF1
MXENFE4ENSG00000230257.1chr7+102618827102618967102626557102626733102613968102614218102628479102628679-0.435000.000380.009272includedK562U2AF1
MXENFE4ENSG00000230257.1chr7+1026188271026189671026265571026267331026139681026142181026284791026286790.151000.013860.082221includedK562AQR
MXENFE4ENSG00000230257.1chr7+102618761102618967102626557102626733102613968102614218102628479102628679-0.434000.000360.006942includedK562U2AF2
MXENFE4ENSG00000230257.1chr7+102618827102618967102626557102626733102613968102614218102628479102628679-0.432000.000080.002062includedK562U2AF2
MXENFE4ENSG00000230257.1chr7+1026187611026189671026265571026267331026139681026142181026284791026286790.365000.000030.001351includedK562HNRNPC
MXENFE4ENSG00000230257.1chr7+1026188271026189671026265571026267331026139681026142181026284791026286790.280000.000000.000001includedK562HNRNPC
MXENFE4ENSG00000230257.1chr7+1026188271026189671026284791026286791026139681026142181026288211026293030.128000.000450.010661includedK562HNRNPC
MXENFE4ENSG00000230257.1chr7+1026188271026189671026265571026267331026139681026142181026284791026286790.214000.000430.081331includedK562FTO
MXENFE4ENSG00000230257.1chr7+102618761102618967102626557102626733102613968102614218102628479102628679-0.300000.001360.067262includedK562HNRNPK
MXENFE4ENSG00000230257.1chr7+102618827102618967102626557102626733102613968102614218102628479102628679-0.275000.000220.019622includedK562HNRNPK

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for NFE4 is not avaliable on ENCORE database.