NF2

General Information

Gene Name       : NF2
Gene ID             : ENSG00000186575.17
Essential Gene : No

Functions

Localization

Domains (AlphaFold: NF2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878NF2ENSG00000186575.179.269.739.50ENCSR000AEF
HepG2NF2ENSG00000186575.1712.4711.9712.22ENCSR985KAT
K562NF2ENSG00000186575.176.566.106.33ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for NF2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • NF2 RNA is bound by 10 proteins.  







eCLIP assay for NF2 is not avaliable on ENCORE database.





10 proteins are bound to NF2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr223009104830091128+3'-UTR3.894023.07786HepG2UPF1
chr223009325630093295+3'-UTR3.349213.42164K562UPF1
chr223009424930094360+3'-UTR4.4138511.27127K562UPF1
chr223007911830079197+3'-UTR,intron-Distal,intron-Proximal5.070986.62122HepG2RBFOX2
chr223009123430091363+3'-UTR4.694865.41597HepG2UPF1
chr223009121930091266+3'-UTR3.849214.87320K562UPF1
chr223009235130092394+3'-UTR5.414719.47550K562UPF1
chr223009207230092093+3'-UTR3.464457.05885HepG2UPF1
chr223009207330092128+3'-UTR3.3486021.20796K562UPF1
chr223009413230094203+3'-UTR4.271967.50817K562UPF1
chr223007898830079070+3'-UTR,CDS,intron-Distal,intron-Proximal4.740345.81672HepG2U2AF2
chr223007418430074256+3'-UTR,CDS,intron-Distal,intron-Proximal3.819243.46958K562YBX3
chr223009209330092122+3'-UTR3.629977.60345HepG2UPF1
chr222999989930000006+5'-UTR,CDS5.0333410.30616HepG2DDX3X
chr222999963029999806+5'-UTR3.892755.21590K562DDX3X
chr222999962829999818+5'-UTR4.5777033.06657HepG2DDX3X
chr222999981829999899+5'-UTR4.562276.15796HepG2DDX3X
chr223000001630000120+CDS,intron-Proximal4.305335.42152HepG2GRWD1
chr223006781230067929+CDS,intron-Distal,intron-Proximal4.190594.21087HepG2GRWD1
chr223006432230064436+CDS,intron-Distal,intron-Proximal4.570804.07072K562UCHL5
chr223003514630035250+CDS,intron-Distal,intron-Proximal3.334663.76553K562PRPF8
chr223003275230032868+CDS,intron-Distal,intron-Proximal4.406354.91614HepG2GRWD1
chr223006097830061054+CDS,intron-Distal,intron-Proximal4.264314.16170K562UCHL5
chr223003846030038547+intron-Distal4.023983.46495K562TARDBP
chr223004654230046716+intron-Distal4.262088.04896HepG2PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for NF2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for NF2 is not available on ENCORE database.

  • 56 RBPs can affect the levels of NF2.  








The Knockdown/knockout RNA-Seq assay for NF2 is not available on ENCORE database.





56 RBPs can affect the gene expression of NF2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
NF2ENSG00000186575.13721.00140543.280400.408204.228003.50650HepG2ACO1
NF2ENSG00000186575.131028.58240545.329500.915409.094808.19290HepG2AKAP1
NF2ENSG00000186575.13310.63360451.19410-0.538503.088002.25930HepG2ASCC1
NF2ENSG00000186575.13726.55380585.722500.310801.805701.31290HepG2BOP1
NF2ENSG00000186575.13718.81810543.150900.404204.285903.49210HepG2CKAP4
NF2ENSG00000186575.13649.52030520.916700.318202.148501.57090HepG2CELF1
NF2ENSG00000186575.13763.25090560.202200.446104.802603.86570HepG2DAZAP1
NF2ENSG00000186575.13867.30040522.340900.731406.638305.71150HepG2DDX3X
NF2ENSG00000186575.13637.24970448.804200.505702.930002.29620HepG2DDX6
NF2ENSG00000186575.13222.02260396.06630-0.835007.976206.83230HepG2DNAJC21
NF2ENSG00000186575.13681.05450476.637300.514803.153602.47200HepG2EIF4A3
NF2ENSG00000186575.13327.49340464.16720-0.503202.207101.58990HepG2EIF4B
NF2ENSG00000186575.13731.77970481.056000.605104.667403.78460HepG2FXR1
NF2ENSG00000186575.13357.41930514.79900-0.526402.491901.59890HepG2HNRNPA2B1
NF2ENSG00000186575.13338.18020581.70680-0.782506.581405.65610HepG2HNRNPLL
NF2ENSG00000186575.13667.65120453.495800.557903.953403.16020HepG2IGF2BP2
NF2ENSG00000186575.13838.39900481.224600.800807.769806.68550HepG2MAGOH
NF2ENSG00000186575.13837.57170483.893700.791406.894705.93090HepG2MATR3
NF2ENSG00000186575.13232.83410593.26740-1.3494011.420009.44410HepG2MTPAP
NF2ENSG00000186575.13973.58020495.272400.9750011.204409.97260HepG2NCBP2
NF2ENSG00000186575.13288.13480515.79500-0.840106.923105.77350HepG2NSUN2
NF2ENSG00000186575.13776.07370449.932500.7864012.4478011.30820HepG2PCBP1
NF2ENSG00000186575.13630.32150431.731700.545902.788401.56780HepG2PRPF6
NF2ENSG00000186575.13805.06980457.827900.8142013.0742012.06010HepG2PTBP1
NF2ENSG00000186575.13406.46160562.45090-0.468603.725102.95220HepG2PUM2
NF2ENSG00000186575.13748.84810553.364700.436304.766704.00020HepG2PUS1
NF2ENSG00000186575.13754.05740495.828900.604706.439305.54280HepG2QKI
NF2ENSG00000186575.13615.50250450.000400.451703.300902.56980HepG2RBM25
NF2ENSG00000186575.13875.77190509.514600.7813011.9960011.02090HepG2NELFE
NF2ENSG00000186575.13618.12940474.550600.381203.007402.36850HepG2RECQL
NF2ENSG00000186575.13545.48440389.518300.485702.230901.38130HepG2RPS10
NF2ENSG00000186575.13501.69580355.391400.497302.435301.69380HepG2RRP9
NF2ENSG00000186575.131343.07250632.125601.0872012.2797010.80100HepG2SF3A3
NF2ENSG00000186575.13734.01700476.649500.622807.585906.68550HepG2SF3B4
NF2ENSG00000186575.13610.63020404.964300.592403.376802.30700HepG2SMNDC1
NF2ENSG00000186575.13428.09050640.65000-0.581602.876702.07940HepG2SNRNP70
NF2ENSG00000186575.131077.18220884.008600.285002.763702.26240HepG2SRFBP1
NF2ENSG00000186575.13905.78990497.522300.8643015.2779014.35810HepG2SRSF1
NF2ENSG00000186575.13644.40680523.499900.299701.980901.44000HepG2SRSF5
NF2ENSG00000186575.13266.48170463.70750-0.799205.616204.70490HepG2SUPV3L1
NF2ENSG00000186575.13306.77740447.20190-0.543704.165703.49890HepG2TAF15
NF2ENSG00000186575.131124.17670530.781301.0826016.0687014.50660HepG2U2AF1
NF2ENSG00000186575.13871.95920541.235000.6879010.948209.88430HepG2UTP3
NF2ENSG00000186575.13429.05380525.30750-0.292001.990301.40670HepG2ZC3H8
NF2ENSG00000186575.13607.51270442.359300.457602.959002.01510K562EFTUD2
NF2ENSG00000186575.13634.07010473.587600.420902.260101.33590K562EIF3D
NF2ENSG00000186575.13698.79110517.535300.433103.914103.21290K562FXR1
NF2ENSG00000186575.13201.13460310.04880-0.624302.909502.18110K562G3BP2
NF2ENSG00000186575.13607.43770801.62520-0.400202.961402.18040K562GRSF1
NF2ENSG00000186575.131039.80650826.965000.330302.441101.59480K562MBNL1
NF2ENSG00000186575.13500.91130643.26030-0.360802.885902.05960K562MTPAP
NF2ENSG00000186575.13728.64420402.089500.857609.842007.95300K562PCBP2
NF2ENSG00000186575.13597.64870430.467700.473302.871602.10910K562PRPF8
NF2ENSG00000186575.13819.42520439.061600.9001013.4480012.03810K562PTBP1
NF2ENSG00000186575.13785.89380988.96700-0.331603.158402.13440K562PUM2
NF2ENSG00000186575.13826.73210672.134200.298602.204401.66500K562RBM15
NF2ENSG00000186575.13618.75210421.005500.555404.541603.43400K562RBM22
NF2ENSG00000186575.13592.92500410.401700.530703.759202.05310K562RBM34
NF2ENSG00000186575.13580.31730430.427200.431003.062802.32210K562SRSF1
NF2ENSG00000186575.13575.54940435.619400.401802.411201.74850K562TARDBP
NF2ENSG00000186575.13315.15460441.08370-0.485002.706401.70040K562UCHL5
NF2ENSG00000186575.13647.86960805.75510-0.314602.083501.34560K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for NF2 is not available on ENCORE database.





11 RBPs can affect the splicing of NF2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SENF2ENSG00000186575.13chr22+3007900830079053300774273007759030090740300945830.433000.000710.06033includedHepG2G3BP1
SENF2ENSG00000186575.13chr22+3007900830079053300774273007759030090740300945830.283000.002500.04367includedK562SRSF1
SENF2ENSG00000186575.13chr22+3007900830079053300774273007759030090740300945830.155000.000440.09315includedK562PUM1
SENF2ENSG00000186575.13chr22+300790083007905330077427300775903009074030094583-0.172000.000460.00883excludedK562PUS1
SENF2ENSG00000186575.13chr22+3007900830079053300774273007759030090740300945830.459000.000030.00231includedHepG2MATR3
SENF2ENSG00000186575.13chr22+300790083007905330077427300775903009074030094583-0.169000.000920.02573excludedK562RBM15
SENF2ENSG00000186575.13chr22+3007900830079053300774273007759030090740300945830.472000.000620.07215includedHepG2KHSRP
A5SSNF2ENSG00000186575.13chr22+3007418430074391300741843007431230077427300775900.059000.000700.01367longerK562AQR
MXENF2ENSG00000186575.13chr22+3003273930032865300350783003520129999987300001013003819030038274-0.273000.002530.044482includedHepG2FTO
MXENF2ENSG00000186575.13chr22+30057193300573283006097830061053300541773005425330064321300644350.150000.006090.072271includedHepG2HNRNPUL1
MXENF2ENSG00000186575.13chr22+3003273930032865300350783003520129999987300001013003819030038274-0.291000.002630.040472includedK562SF3B4

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for NF2 is not avaliable on ENCORE database.