NEDD8-MDP1

General Information

Gene Name       : NEDD8-MDP1
Gene ID             : ENSG00000255526.6
Essential Gene : No

Functions

Localization

Domains (AlphaFold: NEDD8-MDP1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878NEDD8-MDP1ENSG00000255526.61.230.180.70ENCSR000AEF
HepG2NEDD8-MDP1ENSG00000255526.61.442.221.83ENCSR985KAT
K562NEDD8-MDP1ENSG00000255526.60.000.250.12ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for NEDD8-MDP1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • NEDD8-MDP1 RNA is bound by 29 proteins.  







eCLIP assay for NEDD8-MDP1 is not avaliable on ENCORE database.





29 proteins are bound to NEDD8-MDP1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr142468474124684792-3'-UTR,CDS,intron-Distal,intron-Proximal4.3022811.67817HepG2PRPF8
chr142468475424684799-3'-UTR,CDS,intron-Distal,intron-Proximal3.270704.68592HepG2PPIG
chr142470148124701506-5'-UTR,intron-Distal,intron-Proximal3.4575816.37623HepG2GRWD1
chr142470145424701481-5'-UTR,CDS,intron-Distal4.5011922.38767HepG2GRWD1
chr142470148924701563-5'-UTR,intron-Distal,intron-Proximal3.7266010.26816K562DDX3X
chr142470145324701557-5'-UTR,CDS,intron-Distal,intron-Proximal3.0678210.76810K562ZNF622
chr142470145524701487-5'-UTR,CDS,intron-Distal4.208726.99054K562DDX55
chr142468758624687647-CDS,intron-Distal,intron-Proximal3.028684.50012HepG2FTO
chr142468740324687470-CDS,intron-Distal,intron-Proximal4.8412614.08248HepG2SF3B4
chr142468758924687621-CDS,intron-Distal,intron-Proximal3.6917221.08645HepG2GRWD1
chr142468758824687619-CDS,intron-Distal,intron-Proximal3.070128.19895HepG2ZNF800
chr142468734124687385-CDS,intron-Distal3.9824016.99896HepG2LARP4
chr142468732924687425-3'-UTR,CDS,intron-Distal,intron-Proximal3.0247920.54702HepG2AQR
chr142468640524686441-3'-UTR,CDS,intron-Distal,intron-Proximal3.791076.67313HepG2BCLAF1
chr142468758924687616-CDS,intron-Distal,intron-Proximal3.5048719.92431HepG2LARP4
chr142468737824687452-CDS,intron-Distal,intron-Proximal3.769266.86197HepG2PRPF8
chr142470144624701467-CDS,intron-Distal3.3193312.28725HepG2PRPF8
chr142468758824687628-CDS,intron-Distal,intron-Proximal3.6923210.76678K562UCHL5
chr142468733724687360-CDS,intron-Distal,intron-Proximal3.5249410.09142HepG2GRWD1
chr142468761624687636-CDS,intron-Distal3.069757.54974HepG2LARP4
chr142468735424687417-CDS,intron-Distal3.708435.13092K562APOBEC3C
chr142468738924687399-CDS,intron-Distal3.1935812.77913HepG2GRWD1
chr142468741824687421-CDS,intron-Distal3.0003810.85786HepG2GRWD1
chr142468639524686453-3'-UTR,CDS,intron-Distal,intron-Proximal3.0181811.63693HepG2U2AF2
chr142468762124687638-CDS,intron-Distal,intron-Proximal4.1621812.94750HepG2GRWD1
chr142468736724687421-CDS,intron-Distal3.322817.02736K562PABPC4
chr142468738524687422-CDS,intron-Distal,intron-Proximal4.0893527.04926HepG2LARP4
chr142468732624687422-3'-UTR,CDS,intron-Distal,intron-Proximal3.2744826.63658HepG2BCLAF1
chr142468733824687423-CDS,intron-Distal,intron-Proximal3.1414815.84185K562ZNF800
chr142468730424687351-3'-UTR,CDS,intron-Distal,intron-Proximal5.465817.02967HepG2PRPF8
chr142468761124687639-CDS,intron-Distal,intron-Proximal3.515285.60676K562DDX55
chr142468756024687599-CDS,intron-Distal,intron-Proximal4.1837111.50355HepG2PRPF8
chr142468739924687409-CDS,intron-Distal3.3314213.83511HepG2GRWD1
chr142468740924687418-CDS,intron-Distal3.2296013.76316HepG2GRWD1
chr142468736024687389-CDS,intron-Distal3.8888512.72593HepG2GRWD1
chr142468733024687423-3'-UTR,CDS,intron-Distal,intron-Proximal3.4530514.44062K562UCHL5
chr142468622124686283-3'-UTR,intron-Distal,intron-Proximal5.09032400.00000HepG2LARP4
chr142470141524701452-intron-Distal3.917547.80656HepG2GRWD1
chr142468622024686256-3'-UTR,intron-Distal,intron-Proximal3.9283238.04414HepG2DDX55
chr142468613524686225-3'-UTR,intron-Distal,intron-Proximal3.3455116.97396HepG2GRWD1
chr142470141124701446-intron-Distal4.2210613.03969HepG2PRPF8
chr142468617724686200-3'-UTR,intron-Distal,intron-Proximal5.2036643.07582HepG2LARP4
chr142468609624686172-3'-UTR,intron-Distal,intron-Proximal3.949273.78929K562NOLC1
chr142468608624686140-3'-UTR,intron-Distal,intron-Proximal5.0639533.61192HepG2LARP4
chr142468618124686216-3'-UTR,intron-Distal,intron-Proximal3.933326.88718HepG2AKAP1
chr142469255224692609-intron-Distal3.968937.21362HepG2ILF3
chr142468614824686232-3'-UTR,intron-Distal,intron-Proximal4.303997.11997HepG2SUB1
chr142468615124686328-3'-UTR,intron-Distal,intron-Proximal3.031863.38426HepG2UPF1
chr142468630024686353-3'-UTR,CDS,intron-Distal,intron-Proximal6.0778159.55867HepG2LARP4
chr142468609424686155-3'-UTR,intron-Distal,intron-Proximal3.5729415.19016HepG2DDX55
chr142468601724686069-3'-UTR,intron-Distal,intron-Proximal,polyA_site3.698813.14687K562CSTF2T
chr142468609724686150-3'-UTR,intron-Distal,intron-Proximal4.204654.31023HepG2LIN28B
chr142468615024686216-3'-UTR,intron-Distal,intron-Proximal5.1244910.68247K562PABPC4
chr142470099824701084-intron-Distal,intron-Proximal3.374656.31016HepG2HNRNPK
chr142468632224686347-3'-UTR,CDS,intron-Distal,intron-Proximal4.399668.80691HepG2GRWD1
chr142468500324685057-intron-Distal,intron-Proximal4.221204.32536HepG2SF3B4
chr142469786724697930-intron-Distal3.087968.47905HepG2HNRNPC
chr142468615024686177-3'-UTR,intron-Distal,intron-Proximal4.6136125.26190HepG2LARP4
chr142468630324686316-3'-UTR,intron-Distal,intron-Proximal3.332575.53331HepG2GRWD1
chr142468634724686376-3'-UTR,CDS,intron-Distal,intron-Proximal3.528016.39282HepG2GRWD1
chr142468679224686842-intron-Distal,intron-Proximal3.999146.02363HepG2U2AF2
chr142468617724686223-3'-UTR,intron-Distal,intron-Proximal4.6584118.10022HepG2LIN28B
chr142468628324686300-3'-UTR,intron-Distal,intron-Proximal4.9998355.86410HepG2LARP4
chr142468626324686303-3'-UTR,intron-Distal,intron-Proximal3.2145418.62284HepG2GRWD1
chr142469622024696283-intron-Distal3.827016.09419HepG2KHSRP
chr142468621624686287-3'-UTR,intron-Distal,intron-Proximal4.4571018.24884K562PABPC4
chr142468628724686319-3'-UTR,intron-Distal,intron-Proximal4.815805.42839K562PABPC4
chr142468742524687469-intron-Distal,intron-Proximal3.867475.90528HepG2AQR
chr142468618124686224-3'-UTR,intron-Distal,intron-Proximal3.725823.43526K562GRWD1
chr142468625624686325-3'-UTR,intron-Distal,intron-Proximal4.3743851.70489HepG2DDX55
chr142468623024686326-3'-UTR,intron-Distal,intron-Proximal3.488595.18217K562PUM1
chr142468608624686150-3'-UTR,intron-Distal,intron-Proximal4.782249.84602K562PABPC4
chr142469617824696289-intron-Distal3.355034.35650K562KHSRP
chr142469285124692930-intron-Distal3.442998.12901HepG2ILF3
chr142468608524686148-3'-UTR,intron-Distal,intron-Proximal3.810295.31144HepG2SUB1
chr142469809124698195-intron-Distal3.207145.19856HepG2PTBP1
chr142468539724685457-intron-Distal3.223823.92299HepG2CSTF2T
chr142469254324692612-intron-Distal3.099964.63037HepG2HNRNPC
chr142468621624686313-3'-UTR,intron-Distal,intron-Proximal3.261349.91988HepG2AKAP1
chr142468612924686181-3'-UTR,intron-Distal,intron-Proximal3.054326.27467HepG2AKAP1
chr142470117324701236-intron-Distal,intron-Proximal3.299233.85440HepG2HNRNPC
chr142468616824686222-3'-UTR,intron-Distal,intron-Proximal4.777415.00488K562LIN28B
chr142468596424686073-3'-UTR,intron-Distal,intron-Proximal,polyA_site3.861535.18472HepG2CSTF2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for NEDD8-MDP1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for NEDD8-MDP1 is not available on ENCORE database.

  • 15 RBPs can affect the levels of NEDD8-MDP1.  








The Knockdown/knockout RNA-Seq assay for NEDD8-MDP1 is not available on ENCORE database.





15 RBPs can affect the gene expression of NEDD8-MDP1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
NEDD8-MDP1ENSG00000255526.231.206204.859902.682704.045502.70040HepG2FASTKD2
NEDD8-MDP1ENSG00000255526.2283.09270126.421301.162903.134102.33840HepG2NSUN2
NEDD8-MDP1ENSG00000255526.21.0506013.83540-3.719002.702301.98790HepG2PABPC4
NEDD8-MDP1ENSG00000255526.290.0371052.369100.781702.157901.46720HepG2PRPF4
NEDD8-MDP1ENSG00000255526.235.28270118.83030-1.751906.963504.14170HepG2RBM14
NEDD8-MDP1ENSG00000255526.286.1546025.258501.770102.264801.63790HepG2RPLP0
NEDD8-MDP1ENSG00000255526.216.263300.778204.385203.724001.94910K562CEBPZ
NEDD8-MDP1ENSG00000255526.27.040800.0000099999.999901.982301.45350K562FXR1
NEDD8-MDP1ENSG00000255526.25.6640025.82850-2.189103.196702.30480K562KIF1C
NEDD8-MDP1ENSG00000255526.28.866700.0000099999.999902.182901.51250K562PRPF8
NEDD8-MDP1ENSG00000255526.227.156204.935002.460102.287501.47260K562PSIP1
NEDD8-MDP1ENSG00000255526.21.2469023.51850-4.237304.769704.01130K562RBM15
NEDD8-MDP1ENSG00000255526.223.591600.877204.749105.278302.86040K562SLTM
NEDD8-MDP1ENSG00000255526.220.828705.020402.052602.296001.44680K562TRIM56
NEDD8-MDP1ENSG00000255526.210.261200.0000099999.999902.741801.72810K562UCHL5
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for NEDD8-MDP1 is not available on ENCORE database.





9 RBPs can affect the splicing of NEDD8-MDP1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SENEDD8-MDP1ENSG00000255526.2chr14-247008572470094324687276246874212470145524701542-0.452000.005540.07998excludedK562SF3B4
SENEDD8-MDP1ENSG00000255526.2chr14-2470085724700943246875892468763724701455247015420.063000.000000.00000includedK562HNRNPC
A3SSNEDD8-MDP1ENSG00000255526.2chr14-2468758924687734246875892468763724700857247009430.371000.000000.00000longerK562AQR
A3SSNEDD8-MDP1ENSG00000255526.2chr14-246875892468776024687589246876912470145524701542-0.424000.012040.06195shorterK562AQR
MXENEDD8-MDP1ENSG00000255526.2chr14-24684942246850032468639124686429246847572468486824687338246874210.066000.000090.003151includedK562DROSHA
MXENEDD8-MDP1ENSG00000255526.2chr14-2468494224685003246863912468642924684757246848682468733824687421-0.052000.000040.010692includedHepG2SUGP2
MXENEDD8-MDP1ENSG00000255526.2chr14-24687264246874492468758924687664246863912468642924701455247015420.263000.000690.006601includedK562AQR
MXENEDD8-MDP1ENSG00000255526.2chr14-24684942246850032468639124686468246847572468486824687338246874210.660000.000000.000011includedK562AQR
MXENEDD8-MDP1ENSG00000255526.2chr14-24687264246874212468758924687664246863912468642924701455247015420.254000.000660.006361includedK562AQR
MXENEDD8-MDP1ENSG00000255526.2chr14-2468726424687449246875892468763724686391246864292470145524701542-0.073000.000000.000002includedK562AQR
MXENEDD8-MDP1ENSG00000255526.2chr14-2468726424687421246875892468763724686391246864292470145524701542-0.076000.000000.000002includedK562AQR
MXENEDD8-MDP1ENSG00000255526.2chr14-2468726424687421246875892468763724686391246864292470145524701542-0.051000.000000.000002includedHepG2SF3A3
MXENEDD8-MDP1ENSG00000255526.2chr14-2468733824687421246875892468763724686391246864292470145524701542-0.097000.000000.000012includedHepG2SFPQ
MXENEDD8-MDP1ENSG00000255526.2chr14-24687264246874212468758924687760246863912468642924701455247015420.301000.000110.001271includedHepG2U2AF2
MXENEDD8-MDP1ENSG00000255526.2chr14-24684942246850032468639124686429246847572468486824687338246874210.117000.001350.010391includedHepG2U2AF2
MXENEDD8-MDP1ENSG00000255526.2chr14-2468733824687421246875892468763724686391246864292470145524701542-0.077000.000010.000182includedHepG2U2AF2
MXENEDD8-MDP1ENSG00000255526.2chr14-2468494224685003246863912468642924684757246848682468733824687421-0.090000.001500.043972includedK562DHX30

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for NEDD8-MDP1 is not avaliable on ENCORE database.