DFFB

General Information

Gene Name       : DFFB
Gene ID             : ENSG00000169598.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: DFFB)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878DFFBENSG00000169598.154.664.624.64ENCSR000AEF
HepG2DFFBENSG00000169598.155.006.035.52ENCSR985KAT
K562DFFBENSG00000169598.157.868.568.21ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for DFFB is not avaliable on ENCORE database.



Proteins bound to RNA
  • DFFB RNA is bound by 7 proteins.  







eCLIP assay for DFFB is not avaliable on ENCORE database.





7 proteins are bound to DFFB RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr138008653800922+3'-UTR,intron-Distal4.078933.20319K562UPF1
chr138016953801749+3'-UTR3.606333.01531K562YBX3
chr137825333782614+5'-UTR,CDS,intron-Proximal3.987553.86479HepG2PRPF8
chr137859703786045+intron-Distal4.810866.08124K562AGGF1
chr137765023776621+intron-Distal3.094663.19404HepG2PTBP1
chr137851383785311+intron-Distal5.047453.71677HepG2HNRNPL
chr137765023776620+intron-Distal3.407375.56436K562PTBP1
chr137851513785272+intron-Distal3.616233.87859HepG2AGGF1
chr137804293780497+intron-Distal4.010983.95960K562SAFB2
chr137854513785498+intron-Distal4.847695.18780K562AGGF1
chr137851793785283+intron-Distal7.1413931.08837K562AGGF1
chr137859323786023+intron-Distal4.038103.59673K562HNRNPL
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for DFFB is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for DFFB is not available on ENCORE database.

  • 39 RBPs can affect the levels of DFFB.  








The Knockdown/knockout RNA-Seq assay for DFFB is not available on ENCORE database.





39 RBPs can affect the gene expression of DFFB :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
DFFBENSG00000169598.11158.96400241.41300-0.602803.474402.72060HepG2AUH
DFFBENSG00000169598.1160.20650115.23560-0.936603.140902.50740HepG2BOP1
DFFBENSG00000169598.11198.3616093.950401.078105.560704.48710HepG2CIRBP
DFFBENSG00000169598.1160.68450105.79130-0.801802.313501.67700HepG2CPSF6
DFFBENSG00000169598.11193.10030106.217200.862205.646504.51040HepG2DDX19B
DFFBENSG00000169598.11189.88100114.484200.729802.877002.24030HepG2DDX3X
DFFBENSG00000169598.1163.14110120.13420-0.928002.552701.61510HepG2DDX59
DFFBENSG00000169598.1156.5297098.34950-0.798901.991701.46010HepG2DDX6
DFFBENSG00000169598.11165.79070105.419500.653102.275401.64560HepG2FXR1
DFFBENSG00000169598.11198.2194099.028601.001104.907403.99800HepG2HNRNPK
DFFBENSG00000169598.11212.65300108.542200.970104.773903.95520HepG2NCBP2
DFFBENSG00000169598.11141.4011097.160300.541302.050101.56670HepG2PTBP1
DFFBENSG00000169598.11160.9174095.496000.752703.096702.38760HepG2RBM25
DFFBENSG00000169598.11163.4599099.715600.712902.311201.34470HepG2RCC2
DFFBENSG00000169598.11173.18880108.126900.679502.624402.09510HepG2NELFE
DFFBENSG00000169598.11177.88210100.711200.820603.940403.22180HepG2RECQL
DFFBENSG00000169598.1194.86190181.03400-0.932404.626903.77460HepG2RPLP0
DFFBENSG00000169598.11187.14380101.149600.887604.555103.82470HepG2SF3B4
DFFBENSG00000169598.11196.76090105.581100.898004.085203.53810HepG2SRSF1
DFFBENSG00000169598.11111.20920165.08040-0.569902.574801.90170HepG2SRSF7
DFFBENSG00000169598.1179.64140139.47850-0.808502.303801.67900HepG2SUPV3L1
DFFBENSG00000169598.11183.9869094.908100.954905.177304.45030HepG2TAF15
DFFBENSG00000169598.11184.67940106.520900.793803.130502.46470HepG2U2AF1
DFFBENSG00000169598.11360.59580493.20900-0.451802.603801.42650K562ABCF1
DFFBENSG00000169598.11391.25580280.565900.479702.743302.09300K562AKAP8L
DFFBENSG00000169598.11388.23410294.379700.399102.398701.55330K562ATP5C1
DFFBENSG00000169598.11317.83800480.27640-0.595604.188703.33100K562EIF2S2
DFFBENSG00000169598.11377.72740287.717800.392602.226701.67290K562FXR1
DFFBENSG00000169598.11133.27470242.55990-0.863904.826004.05840K562HNRNPC
DFFBENSG00000169598.11125.74630209.20700-0.734402.760801.82870K562KRR1
DFFBENSG00000169598.11406.85000284.099000.518002.546701.73960K562MAGOH
DFFBENSG00000169598.11462.94210333.558600.472803.181002.19380K562MBNL1
DFFBENSG00000169598.11254.01350338.86760-0.415802.231801.50220K562MTPAP
DFFBENSG00000169598.11212.76610330.40030-0.634903.367402.45010K562PCBP3
DFFBENSG00000169598.11165.98880253.43550-0.610503.300902.42100K562POLR2G
DFFBENSG00000169598.11385.21170271.108100.506703.272002.63570K562RBM15
DFFBENSG00000169598.11318.21490210.772600.594204.007102.97100K562SF3B4
DFFBENSG00000169598.11365.19670270.574100.432502.310601.65700K562SRSF1
DFFBENSG00000169598.11345.38340254.192500.442202.412701.64610K562SYNCRIP
DFFBENSG00000169598.11373.47740522.69690-0.485003.749802.26190K562TROVE2
DFFBENSG00000169598.11203.52190286.16120-0.491602.244201.33550K562UCHL5
DFFBENSG00000169598.11476.38090617.97550-0.375402.466701.65990K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for DFFB is not available on ENCORE database.





3 RBPs can affect the splicing of DFFB :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEDFFBENSG00000169598.11chr1+378957737897013789035378913638000703801993-0.197000.000530.07107excludedK562DROSHA
SEDFFBENSG00000169598.11chr1+3782847378296237823753782564378453737846170.476000.000310.06491includedK562SBDS
SEDFFBENSG00000169598.11chr1+3789577378970137890353789136380007038019930.399000.000000.00000includedK562HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for DFFB is not avaliable on ENCORE database.