DCP1B

General Information

Gene Name       : DCP1B
Gene ID             : ENSG00000151065.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: DCP1B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878DCP1BENSG00000151065.1312.8812.2112.55ENCSR000AEF
HepG2DCP1BENSG00000151065.1310.3511.5310.94ENCSR985KAT
K562DCP1BENSG00000151065.133.464.253.85ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
DCP1BENCAB164GPFA303-641A1Released, ENCODE4


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
DCP1BK562CRISPRBGKcLV44-9,BGKcLV44-10BGKcLV44-1,BGKcLV44-20.0,0.0NotSatisfiedENCORE2
DCP1BK562CRISPRBGKcLV44-11,BGKcLV44-12BGKcLV44-1,BGKcLV44-20.0,0.0NotSatisfiedENCORE2
DCP1BHepG2CRISPRBGHcLV45-15,BGHcLV45-16BGHcLV45-1,BGHcLV45-287.7,84.8SequencingENCORE2
DCP1BHepG2CRISPRBGHcLV45-17,BGHcLV45-18BGHcLV45-1,BGHcLV45-275.5,55.9NotSatisfiedENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
DCP1BProduct_ID: A303-641A
Lot_ID: 1
Source: Bethyl Labs
Target Name: DCP1B-human		 Bethyl_A303-641A_1_DCP1B.png<br>Caption: IP-WB analysis of K562 whole cell lysate using the DCP1B specific antibody, A303-641A. Lanes 1 and 2 are 2.5% of five million whole cell lysate input and 50% of IP enrichment, respectively, using a normal IgG antibody. Lane 3 is 50% of IP enrichment from five million whole cell lysate using the DCP1B-specific antibody, A303-641A. The same antibody was used to detect protein levels via Western blot. This antibody passes preliminary validation and will be further pursued for secondary validation. *NOTE* Protein sizes are taken from Genecards.org and are only estimates based on sequence. Actual protein size may differ based on protein characteristics and electrophoresis method used.








RNA Targets

  • eCLIP assay for DCP1B is not avaliable on ENCORE database.



Proteins bound to RNA
  • DCP1B RNA is bound by 7 proteins.  







eCLIP assay for DCP1B is not avaliable on ENCORE database.





7 proteins are bound to DCP1B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1220582132058277-3'-UTR,CDS,intron-Distal,intron-Proximal4.348786.23016HepG2PRPF8
chr1221135262113599-5'-UTR,CDS,intron-Distal,intron-Proximal3.983663.03048HepG2GTF2F1
chr1221133852113457-5'-UTR,CDS,intron-Distal4.848786.69228HepG2PRPF8
chr1221134042113449-5'-UTR,CDS,intron-Distal4.925213.93614HepG2AQR
chr1221135572113620-5'-UTR,CDS,intron-Distal,intron-Proximal3.110306.28722HepG2NCBP2
chr1221134632113557-5'-UTR,CDS,intron-Distal4.368398.76364HepG2NCBP2
chr1221132442113324-intron-Distal4.585955.59467HepG2PRPF4
chr1220984852098584-intron-Distal4.786789.54872HepG2PTBP1
chr1220941372094198-intron-Distal3.306573.34920HepG2HLTF
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for DCP1B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for DCP1B is not available on ENCORE database.

  • 44 RBPs can affect the levels of DCP1B.  








The Knockdown/knockout RNA-Seq assay for DCP1B is not available on ENCORE database.





44 RBPs can affect the gene expression of DCP1B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
DCP1BENSG00000151065.9233.42890535.63880-1.1983010.882909.89510HepG2AKAP1
DCP1BENSG00000151065.9389.32430304.631700.353802.088401.40870HepG2AKAP8L
DCP1BENSG00000151065.9546.43780704.59100-0.366702.285501.73590HepG2BOP1
DCP1BENSG00000151065.9247.98240161.484100.618702.830301.74330HepG2CSTF2
DCP1BENSG00000151065.9271.47220385.79330-0.507003.294302.60560HepG2CELF1
DCP1BENSG00000151065.9373.52010513.07840-0.458002.459301.86660HepG2DDX3X
DCP1BENSG00000151065.9453.16880604.24110-0.415102.555801.57900HepG2DDX5
DCP1BENSG00000151065.9391.35130290.080100.431902.691502.02260HepG2DKC1
DCP1BENSG00000151065.9416.04160336.335600.306701.990901.42090HepG2DNAJC2
DCP1BENSG00000151065.9265.60040423.69710-0.673804.137503.42070HepG2EIF2S1
DCP1BENSG00000151065.9373.54450483.77210-0.373002.125001.42830HepG2FUBP3
DCP1BENSG00000151065.9271.11670438.25500-0.692904.517703.67640HepG2G3BP1
DCP1BENSG00000151065.9272.10030443.86980-0.706004.892603.98460HepG2HNRNPK
DCP1BENSG00000151065.9183.85070418.10620-1.185304.608903.34880HepG2IGF2BP3
DCP1BENSG00000151065.9299.67110448.08610-0.580402.951201.91000HepG2KHSRP
DCP1BENSG00000151065.9296.69580486.46510-0.713404.840704.01630HepG2NCBP2
DCP1BENSG00000151065.9310.99930433.18100-0.478102.481501.79430HepG2PABPC4
DCP1BENSG00000151065.9396.47020489.41010-0.303801.810501.34980HepG2PTBP1
DCP1BENSG00000151065.9404.22530308.827100.388302.594401.99230HepG2PUS1
DCP1BENSG00000151065.9358.66180530.05390-0.563504.650503.87220HepG2QKI
DCP1BENSG00000151065.9172.49910316.68690-0.876503.791602.97080HepG2RAVER1
DCP1BENSG00000151065.9276.43790481.05400-0.799207.363006.30760HepG2RBM25
DCP1BENSG00000151065.9403.51070544.67060-0.432803.261502.68370HepG2NELFE
DCP1BENSG00000151065.9756.53850585.188000.370402.276201.64740HepG2RPLP0
DCP1BENSG00000151065.9489.80270324.269800.594904.396503.63960HepG2RPS19
DCP1BENSG00000151065.9422.11760337.068100.324502.023901.45950HepG2SAFB2
DCP1BENSG00000151065.9394.85510509.54810-0.367902.467301.90460HepG2SF3B4
DCP1BENSG00000151065.9358.21000531.85420-0.570205.167004.57210HepG2SRSF1
DCP1BENSG00000151065.9498.61920745.26910-0.579803.612902.45370HepG2SRSF3
DCP1BENSG00000151065.9286.63210432.68860-0.594104.441803.77390HepG2SRSF9
DCP1BENSG00000151065.9329.74780478.04110-0.535804.260103.58700HepG2TAF15
DCP1BENSG00000151065.9628.55430367.736000.773306.532205.82410HepG2TIAL1
DCP1BENSG00000151065.9352.78030251.922400.485701.939201.32460HepG2XRN2
DCP1BENSG00000151065.967.62520127.31780-0.912803.490302.86580K562AGGF1
DCP1BENSG00000151065.961.65690132.47700-1.103404.763703.89950K562AKAP8L
DCP1BENSG00000151065.960.26600116.84600-0.955202.827302.23350K562AQR
DCP1BENSG00000151065.9231.58310158.334300.548502.877702.21340K562DDX47
DCP1BENSG00000151065.9131.6333072.722300.856002.479401.53040K562EIF3A
DCP1BENSG00000151065.9141.1498083.872600.750902.664502.07670K562HNRNPC
DCP1BENSG00000151065.9274.74150185.474400.566802.537501.77200K562HSPD1
DCP1BENSG00000151065.9176.41650105.818100.737302.814101.97450K562PCBP3
DCP1BENSG00000151065.9157.1166081.160600.952904.416203.40120K562POLR2G
DCP1BENSG00000151065.935.19970131.40170-1.900308.830107.90820K562PUS1
DCP1BENSG00000151065.952.36300128.01390-1.289705.829604.99570K562RBM15
DCP1BENSG00000151065.998.2876045.625401.107102.827401.81360K562RPS3
DCP1BENSG00000151065.9132.2503081.413800.699802.481301.70590K562SYNCRIP
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for DCP1B is not available on ENCORE database.





1 RBPs can affect the splicing of DCP1B :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEDCP1BENSG00000151065.9chr12-2100286210041220770092077076210242921025570.330000.000130.00750includedHepG2HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for DCP1B is not avaliable on ENCORE database.