SQSTM1

General Information

Gene Name : SQSTM1
Gene ID : ENSG00000161011.19
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: SQSTM1)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	SQSTM1	ENSG00000161011.19	15.01	36.77	25.89	ENCSR000AEF
HepG2	SQSTM1	ENSG00000161011.19	99.77	65.91	82.84	ENCSR985KAT
K562	SQSTM1	ENSG00000161011.19	57.63	50.43	54.03	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for SQSTM1 is not avaliable on ENCORE database.

Proteins bound to RNA

SQSTM1 RNA is bound by 63 proteins.

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eCLIP assay for SQSTM1 is not avaliable on ENCORE database.

63 proteins are bound to SQSTM1 RNA:

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Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr5	179263761	179263834	+	3'-UTR	5.32539	400.00000	K562	PABPC4
chr5	179263683	179263745	+	3'-UTR	4.18190	42.78550	K562	PABPC4
chr5	179250026	179250066	+	3'-UTR,CDS,intron-Proximal	4.46814	36.61311	HepG2	PRPF8
chr5	179250066	179250093	+	intron-Proximal	4.56486	36.40792	HepG2	PRPF8
chr5	179249901	179249953	+	5'-UTR,CDS,intron-Distal,intron-Proximal	4.86027	31.36942	HepG2	SF3B4
chr5	179249904	179249948	+	5'-UTR,CDS,intron-Distal,intron-Proximal	4.67291	30.44755	HepG2	SF3A3
chr5	179263746	179263832	+	3'-UTR	4.90150	30.31734	HepG2	SUB1
chr5	179251321	179251405	+	CDS,intron-Proximal	5.86628	28.70535	K562	AQR
chr5	179252199	179252270	+	CDS,intron-Proximal	4.23221	25.97318	HepG2	PRPF8
chr5	179248612	179248719	+	5'-UTR,intron-Distal,intron-Proximal	3.69710	24.87582	K562	DROSHA
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 216 entries

eCLIP assay for SQSTM1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for SQSTM1 is not available on ENCORE database.
168 RBPs can affect the levels of SQSTM1.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for SQSTM1 is not available on ENCORE database.

168 RBPs can affect the gene expression of SQSTM1 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
SQSTM1	ENSG00000161011.15	9837.81860	2573.53910	1.93450	289.07640	286.05240	HepG2	ZNF622
SQSTM1	ENSG00000161011.15	15934.21060	3358.17880	2.24630	208.72800	206.15890	HepG2	SRFBP1
SQSTM1	ENSG00000161011.15	7257.57470	2314.52760	1.64870	200.30210	197.27920	HepG2	PUM1
SQSTM1	ENSG00000161011.15	6769.90020	2152.79790	1.65280	137.57080	134.26420	HepG2	SRSF5
SQSTM1	ENSG00000161011.15	8182.97750	3098.35160	1.40100	101.89280	98.98700	HepG2	AUH
SQSTM1	ENSG00000161011.15	11560.08990	2119.50220	2.44730	92.26460	90.02840	HepG2	SRSF9
SQSTM1	ENSG00000161011.15	13704.63370	2292.47330	2.57960	73.88060	70.86230	HepG2	EIF4B
SQSTM1	ENSG00000161011.15	9566.17100	1368.85010	2.80490	57.68610	54.98810	HepG2	RAVER1
SQSTM1	ENSG00000161011.15	4187.48790	1172.47770	1.83640	57.65150	54.19130	HepG2	EIF3D
SQSTM1	ENSG00000161011.15	7331.53520	2425.86610	1.59550	53.76910	50.90470	HepG2	U2AF1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 220 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for SQSTM1 is not available on ENCORE database.

6 RBPs can affect the splicing of SQSTM1 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	SQSTM1	ENSG00000161011.15	chr5	+	179252145	179252226			179251181	179251323	179260031	179260246	-0.06000	0.00000	0.00027	excluded	K562	PRPF8
SE	SQSTM1	ENSG00000161011.15	chr5	+	179252145	179252226			179251181	179251323	179260031	179260246	-0.06900	0.00000	0.00002	excluded	K562	RBM15
MXE	SQSTM1	ENSG00000161011.15	chr5	+	179238573	179238682	179249957	179250053	179233387	179233591	179250857	179251087	-0.08400	0.00000	0.00053	2included	HepG2	LARP4
SE	SQSTM1	ENSG00000161011.15	chr5	+	179252145	179252226			179251181	179251323	179260031	179260246	-0.05100	0.00002	0.00133	excluded	K562	AKAP8L
SE	SQSTM1	ENSG00000161011.15	chr5	+	179252145	179252333			179251181	179251323	179260031	179260386	-0.07700	0.00026	0.01848	excluded	K562	EFTUD2
MXE	SQSTM1	ENSG00000161011.15	chr5	+	179249957	179250053	179250857	179251087	179238573	179238682	179251181	179251323	-0.12800	0.00188	0.03752	2included	K562	PRPF8
SE	SQSTM1	ENSG00000161011.15	chr5	+	179252145	179252226			179251181	179251323	179260031	179260246	-0.06000	0.00190	0.03524	excluded	K562	SF3B4

Showing 1 to 7 of 7 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

SQSTM1

General Information

Functions

Localization

Domains (AlphaFold: SQSTM1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for SQSTM1 is not avaliable on ENCORE database.

63 proteins are bound to SQSTM1 RNA:

eCLIP assay for SQSTM1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for SQSTM1 is not available on ENCORE database.

168 RBPs can affect the gene expression of SQSTM1 :

The Knockdown/knockout RNA-Seq assay for SQSTM1 is not available on ENCORE database.

6 RBPs can affect the splicing of SQSTM1 :

The Knockdown/knockout RNA-Seq assay for SQSTM1 is not avaliable on ENCORE database.