ILF2

General Information

Gene Name : ILF2
Gene ID : ENSG00000143621.16
Essential Gene : Yes

Functions

rRNA processing
microRNA processing
Translation regulation
Viral RNA regulation

Localization(RBPImage: ILF2)

Nuclei
Nucleoplasm
Nucleolus
Cytoplasm
Mitotic-Apparatus (Spindle; Centrosomes)
Nuclear release mitosis

Domains (AlphaFold: ILF2)

No checked domain (RRM, ZNF, KH, Helicase, Nuclease, dRBM or PUM_HD)

Antibody Validation

Bethyl Labs: A303-147A

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	ILF2	ENSG00000143621.16	379.24	353.98	366.61	ENCSR000AEF
HepG2	ILF2	ENSG00000143621.16	283.38	344.16	313.77	ENCSR985KAT
K562	ILF2	ENSG00000143621.16	393.14	446.57	419.86	ENCSR000AEO

Assays

3 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Controls	Method	Note
knockdown followed by RNA-seq	ILF2-BGKLV24-K562	ENCSR126ARZ	ILF2	K562	Released	ENCSR419JMU	shRNA	KD% = 35.0,36.8
knockdown followed by RNA-seq	ILF2-BGHLV20-HepG2	ENCSR366FFV	ILF2	HepG2	Released	ENCSR305XWT	shRNA	KD% = 63.7,65.3
RNA Bind-n-Seq	RBNS: ILF2	ENCSR906EKN	ILF2	cell-free sample	Released	ENCSR391IGH

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
ILF2	ENCAB709CSJ	A303-147A	1		Released, ENCODE3	Released, ENCODE3	BGHLV20-39, Released, ENCODE3	BGKLV24-35, Released, ENCODE3

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
ILF2	K562	shRNA			BGKLV13-21,BGKLV13-22	BGKLV13-1,BGKLV13-2		NotSatisfied	ENCODE3
ILF2	K562	shRNA	ENCSR126ARZ	ENCSR419JMU	ILF2_BGKLV24_35B,ILF2_BGKLV24_36B	non-target_BGKLV24_1B,non-target_BGKLV24_2B	35.0,36.8	Released	ENCODE3
ILF2	HepG2	shRNA	ENCSR366FFV	ENCSR305XWT	ILF2-BGHLV20-39_17728,ILF2-BGHLV20-40_17729	non-target-BGHLV20-1_17706,non-target-BGHLV20-2_17707	63.7,65.3	Released	ENCODE3

RNA Bind-n-Seqn

GeneName	gene_aliases	Status	Project	Note
ILF2	ILF2		Released	ENCODE3

Localization Image in HepG2

ILF2: Click to RBP Image Database

Nuclei

Nucleoplasm

Nucleolus

Cytoplasm

Mitotic-Apparatus (Spindle; Centrosomes)

Nuclear release mitosis

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
ILF2	Product_ID: A303-147A Lot_ID: 1 Source: Bethyl Labs Target Name: ILF2-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for ILF2 is not avaliable on ENCORE database.

The binding motifs of ILF2

Proteins bound to RNA

ILF2 RNA is bound by 32 proteins.

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eCLIP assay for ILF2 is not avaliable on ENCORE database.

32 proteins are bound to ILF2 RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr1	153640934	153640981	-	CDS,intron-Distal	5.31065	49.89661	K562	RPS3
chr1	153634888	153635004	-	CDS,intron-Distal	4.62632	42.25793	K562	UCHL5
chr1	153634804	153634888	-	3'-UTR,CDS,intron-Distal	4.21596	39.46075	K562	UCHL5
chr1	153634668	153634693	-	3'-UTR,intron-Distal	4.28290	29.55262	K562	YBX3
chr1	153634872	153634999	-	3'-UTR,CDS,intron-Distal	4.22118	29.00066	K562	ZNF800
chr1	153634818	153634887	-	3'-UTR,CDS,intron-Distal	4.06349	27.93230	K562	ZNF622
chr1	153634585	153634635	-	3'-UTR,intron-Distal	3.61123	24.66718	K562	PABPC4
chr1	153634860	153635015	-	3'-UTR,CDS,intron-Distal	3.00962	24.62934	K562	GRWD1
chr1	153634761	153634866	-	3'-UTR,intron-Distal	3.66289	23.31787	K562	PABPC4
chr1	153640987	153641026	-	CDS,intron-Distal	5.78167	21.71508	K562	RPS3
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 90 entries

eCLIP assay for ILF2 is not avaliable on ENCORE database.

Diffrential Expression

6,473 differentially expressed genes after Knockdown/Knockout ILF2 protein.

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128 RBPs can affect the levels of ILF2.

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6,473 differentially expressed genes after Knockdown/Knockout ILF2 protein :

Only display 100 entries as example. Please click "View All" button to see all 6,473 entries.

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Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
IL32	ENSG00000008517.12	3613.47750	1614.70840	1.16200	79.48020	76.59310	HepG2	ILF2
SLC7A2	ENSG00000003989.12	2753.47700	5204.86210	-0.91860	60.84590	58.14440	HepG2	ILF2
NCAPD2	ENSG00000010292.8	2213.07910	4211.17890	-0.92820	57.64080	54.99250	HepG2	ILF2
ADIPOR2	ENSG00000006831.9	1616.43940	3086.97020	-0.93340	49.79140	47.26600	HepG2	ILF2
SPAG9	ENSG00000008294.16	1878.83980	3311.33970	-0.81760	33.35100	31.18540	HepG2	ILF2
CSDE1	ENSG00000009307.11	7390.31360	10893.93390	-0.55980	30.70310	28.60840	HepG2	ILF2
TFPI	ENSG00000003436.10	11357.37960	7869.35370	0.52920	27.88680	25.86990	HepG2	ILF2
LYPLA2	ENSG00000011009.6	1419.88090	784.08310	0.85660	26.63120	24.65080	HepG2	ILF2
MGST1	ENSG00000008394.8	1252.21390	1988.23330	-0.66700	20.92000	19.11920	HepG2	ILF2
MYCBP2	ENSG00000005810.13	813.70490	1363.59730	-0.74480	20.78100	18.99420	HepG2	ILF2
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 100 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

128 RBPs can affect the gene expression of ILF2 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
ILF2	ENSG00000143621.12	710.50900	4543.69000	-2.67690	99999.99999	99999.99999	HepG2	ILF2
ILF2	ENSG00000143621.12	2016.10780	3795.42460	-0.91270	36.43500	34.86670	HepG2	SRSF9
ILF2	ENSG00000143621.12	2670.14020	11640.84380	-2.12420	34.30020	30.19500	K562	ILF2
ILF2	ENSG00000143621.12	3617.40110	5863.82040	-0.69690	28.97760	27.71570	HepG2	SSB
ILF2	ENSG00000143621.12	4166.97240	8555.04330	-1.03780	23.39800	21.74280	K562	HNRNPC
ILF2	ENSG00000143621.12	2721.52420	4649.67620	-0.77270	21.75830	20.25010	HepG2	QKI
ILF2	ENSG00000143621.12	2792.78580	4360.91170	-0.64290	21.61650	20.22620	HepG2	TRIM56
ILF2	ENSG00000143621.12	3986.66940	6005.05130	-0.59100	19.76210	18.21230	HepG2	SRSF7
ILF2	ENSG00000143621.12	7673.57950	10121.86030	-0.39950	19.90770	18.16810	K562	NSUN2
ILF2	ENSG00000143621.12	3754.71570	6584.43970	-0.81040	17.58480	16.15410	HepG2	RPLP0
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 159 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for ILF2 is not available on ENCORE database.

15 RBPs can affect the splicing of ILF2 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	is_included	Cell Line	Affected by RBP
SE	ILF2	ENSG00000143621.12	chr1	-	153635690	153635752			153635406	153635609	153636518	153636687	-0.06500	excluded	K562	AQR
A3SS	ILF2	ENSG00000143621.12	chr1	-	153640928	153641136			153640928	153641033	153642311	153642487	0.08400	longer	K562	AQR
A3SS	ILF2	ENSG00000143621.12	chr1	-	153642311	153642384			153642311	153642354	153642646	153642773	0.20900	longer	K562	AQR
A3SS	ILF2	ENSG00000143621.12	chr1	-	153642646	153642831			153642646	153642706	153643393	153643524	0.07100	longer	K562	AQR
A3SS	ILF2	ENSG00000143621.12	chr1	-	153635494	153635752			153635494	153635609	153636518	153636661	-0.09700	shorter	K562	AQR
RI	ILF2	ENSG00000143621.12	chr1	-	153635494	153635752			153635494	153635609	153635690	153635752	0.12400	included	K562	PUS1
RI	ILF2	ENSG00000143621.12	chr1	-	153635494	153635752			153635494	153635609	153635690	153635752	0.05200	included	K562	UTP18
RI	ILF2	ENSG00000143621.12	chr1	-	153635494	153635720			153635494	153635609	153635690	153635720	0.07100	included	K562	AQR
MXE	ILF2	ENSG00000143621.12	chr1	-	153640475	153640553	153640928	153641033	153640030	153640133	153642311	153642354	0.10300	1included	K562	DROSHA
MXE	ILF2	ENSG00000143621.12	chr1	-	153635494	153635609	153636518	153636606	153635180	153635271	153636871	153636950	-0.11100	2included	K562	DROSHA

Showing 1 to 10 of 42 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

ILF2

General Information

Functions

Localization(RBPImage: ILF2)

Domains (AlphaFold: ILF2)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for ILF2 is not avaliable on ENCORE database.

32 proteins are bound to ILF2 RNA:

eCLIP assay for ILF2 is not avaliable on ENCORE database.

Diffrential Expression

6,473 differentially expressed genes after Knockdown/Knockout ILF2 protein :

128 RBPs can affect the gene expression of ILF2 :

The Knockdown/knockout RNA-Seq assay for ILF2 is not available on ENCORE database.

15 RBPs can affect the splicing of ILF2 :

The Knockdown/knockout RNA-Seq assay for ILF2 is not avaliable on ENCORE database.