NAA15

General Information

Gene Name : NAA15
Gene ID : ENSG00000164134.12
Essential Gene : Yes

Functions

Novel RBP

Localization(RBPImage: NAA15)

Nuclei
Nucleoplasm
Mutually Exclusive from Nucleolus
Cytoplasm
Cytosolic

Domains (AlphaFold: NAA15)

No checked domain (RRM, ZNF, KH, Helicase, Nuclease, dRBM or PUM_HD)

Antibody Validation

Bethyl Labs: A302-147A

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	NAA15	ENSG00000164134.12	42.34	34.74	38.54	ENCSR000AEF
HepG2	NAA15	ENSG00000164134.12	11.20	22.70	16.95	ENCSR985KAT
K562	NAA15	ENSG00000164134.12	43.65	51.41	47.53	ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	NAA15-BGKLV32-K562	ENCSR945GUR	NAA15	K562	Released		ENCSR143COQ	shRNA	KD% = 87.0,85.5
knockdown followed by RNA-seq	NAA15-BGHLV30-HepG2	ENCSR355OQC	NAA15	HepG2	Released		ENCSR067GHD	shRNA	KD% = 88.3,89.1

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
NAA15	ENCAB161WRM	A302-147A	1			Released, ENCODE3	BGHLV30-45, Released, ENCODE3	BGKLV32-41, Released, ENCODE3

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project	Note
NAA15	K562	shRNA	ENCSR945GUR	ENCSR143COQ	NAA15_BGKLV32-41,NAA15_BGKLV32-42	NT_BGKLV32-1,NT_BGKLV32-2	87.0,85.5	Released	ENCODE3
NAA15	HepG2	shRNA	ENCSR355OQC	ENCSR067GHD	NAA15_BGHLV30-45,NAA15_BGHLV30-46	NT_BGHLV30-1,NT_BGHLV30-2	88.3,89.1	Released	ENCODE3

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

NAA15: Click to RBP Image Database

Nuclei

Nucleoplasm

Mutually Exclusive from Nucleolus

Cytoplasm

Cytosolic

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
NAA15	Product_ID: A302-147A Lot_ID: 1 Source: Bethyl Labs Target Name: NAA15-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for NAA15 is not avaliable on ENCORE database.

Proteins bound to RNA

NAA15 RNA is bound by 40 proteins.

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eCLIP assay for NAA15 is not avaliable on ENCORE database.

40 proteins are bound to NAA15 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr4	140339799	140339914	+	3'-UTR	7.48329	35.72044	K562	QKI
chr4	140222663	140222751	+	5'-UTR	5.10745	29.19570	K562	DDX3X
chr4	140309526	140309592	+	3'-UTR,intron-Distal	3.61890	27.13060	K562	UPF1
chr4	140291405	140291560	+	CDS,intron-Proximal	3.99472	25.73116	K562	UCHL5
chr4	140309592	140309706	+	3'-UTR,intron-Distal	3.36963	23.48931	K562	UPF1
chr4	140339822	140339885	+	3'-UTR	5.56567	20.95562	HepG2	QKI
chr4	140281649	140281737	+	CDS,intron-Proximal	4.69286	20.21064	HepG2	BCLAF1
chr4	140339885	140339961	+	3'-UTR	5.61593	19.89577	HepG2	QKI
chr4	140291498	140291559	+	CDS,intron-Proximal	5.38349	18.51421	K562	ZNF622
chr4	140278537	140278616	+	CDS,intron-Proximal	4.58355	18.21191	HepG2	BCLAF1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 144 entries

eCLIP assay for NAA15 is not avaliable on ENCORE database.

Diffrential Expression

6,201 differentially expressed genes after Knockdown/Knockout NAA15 protein.

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115 RBPs can affect the levels of NAA15.

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6,201 differentially expressed genes after Knockdown/Knockout NAA15 protein :

Only display 100 entries as example. Please click "View All" button to see all 6,201 entries.

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Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
SLC2A3	ENSG00000059804.11	24456.56480	8164.60460	1.58270	45.07590	41.01650	HepG2	NAA15
CP	ENSG00000047457.9	42833.21790	24411.13350	0.81110	16.30090	13.44560	HepG2	NAA15
RNF19A	ENSG00000034677.7	2277.25920	1235.99060	0.88150	12.54630	10.00530	HepG2	NAA15
HEXB	ENSG00000049860.9	1815.85650	1122.06300	0.69440	10.71210	8.37160	HepG2	NAA15
TACC3	ENSG00000013810.14	710.86830	1304.25140	-0.87560	10.38390	8.08040	HepG2	NAA15
WWTR1	ENSG00000018408.10	3746.16750	2238.36880	0.74290	9.95050	7.70730	HepG2	NAA15
DEPDC1	ENSG00000024526.12	278.72390	569.72360	-1.03140	9.72390	7.50960	HepG2	NAA15
ABCC2	ENSG00000023839.6	8112.12560	5157.18530	0.65340	9.48620	7.29010	HepG2	NAA15
NFE2L3	ENSG00000050344.8	414.24750	222.72690	0.89510	8.80690	6.69930	HepG2	NAA15
TFPI	ENSG00000003436.10	14873.59540	9434.39500	0.65670	8.70430	6.61100	HepG2	NAA15
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 100 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

115 RBPs can affect the gene expression of NAA15 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
NAA15	ENSG00000164134.8	726.87390	3283.94660	-2.17570	53.82440	49.73520	K562	NAA15
NAA15	ENSG00000164134.8	2226.26950	1024.98200	1.11890	44.04270	42.65430	HepG2	SRSF1
NAA15	ENSG00000164134.8	4002.50320	5940.79000	-0.56980	20.14710	18.41330	K562	UPF1
NAA15	ENSG00000164134.8	251.41830	858.48480	-1.77170	20.80690	17.74740	HepG2	NAA15
NAA15	ENSG00000164134.8	3447.07900	6149.44460	-0.83510	17.28930	14.97710	K562	FIP1L1
NAA15	ENSG00000164134.8	3104.54120	5163.22290	-0.73390	16.89580	14.93530	K562	CPSF6
NAA15	ENSG00000164134.8	1076.23300	1687.47320	-0.64890	14.99370	13.99130	HepG2	SSB
NAA15	ENSG00000164134.8	3298.02730	5476.17800	-0.73160	15.26950	13.78730	K562	EIF2S2
NAA15	ENSG00000164134.8	4895.96660	8337.48300	-0.76800	14.92540	13.15590	K562	HSPD1
NAA15	ENSG00000164134.8	4350.25510	5602.82860	-0.36510	13.50170	12.02670	K562	NSUN2
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 135 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for NAA15 is not available on ENCORE database.

6 RBPs can affect the splicing of NAA15 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	NAA15	ENSG00000164134.8	chr4	+	140307286	140307384			140299909	140300008	140309037	140312522	-0.10900	0.00000	0.00000	excluded	K562	AQR
MXE	NAA15	ENSG00000164134.8	chr4	+	140299909	140300008	140307286	140307384	140291364	140291558	140309037	140312522	0.08400	0.00000	0.00000	1included	K562	AQR
MXE	NAA15	ENSG00000164134.8	chr4	+	140275155	140275252	140278539	140278709	140272688	140272765	140280896	140281011	0.06100	0.00001	0.00009	1included	K562	AQR
SE	NAA15	ENSG00000164134.8	chr4	+	140307286	140307384			140299909	140300008	140309037	140312522	-0.12700	0.00011	0.00258	excluded	K562	PUS1
SE	NAA15	ENSG00000164134.8	chr4	+	140305985	140306132			140299909	140300008	140307286	140307384	-0.05700	0.00101	0.02019	excluded	K562	U2AF2
SE	NAA15	ENSG00000164134.8	chr4	+	140307286	140307384			140299909	140300008	140309037	140312522	-0.08100	0.00141	0.02765	excluded	K562	SF3B4
SE	NAA15	ENSG00000164134.8	chr4	+	140277642	140277737			140275179	140275252	140278539	140278709	0.05900	0.00268	0.04284	included	K562	HNRNPC
SE	NAA15	ENSG00000164134.8	chr4	+	140307286	140307384			140299909	140300008	140309037	140312522	-0.06700	0.00391	0.06760	excluded	K562	U2AF1

Showing 1 to 8 of 8 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

NAA15

General Information

Functions

Localization(RBPImage: NAA15)

Domains (AlphaFold: NAA15)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for NAA15 is not avaliable on ENCORE database.

40 proteins are bound to NAA15 RNA:

eCLIP assay for NAA15 is not avaliable on ENCORE database.

Diffrential Expression

6,201 differentially expressed genes after Knockdown/Knockout NAA15 protein :

115 RBPs can affect the gene expression of NAA15 :

The Knockdown/knockout RNA-Seq assay for NAA15 is not available on ENCORE database.

6 RBPs can affect the splicing of NAA15 :

The Knockdown/knockout RNA-Seq assay for NAA15 is not avaliable on ENCORE database.