MTHFD1L

General Information

Gene Name : MTHFD1L
Gene ID : ENSG00000120254.15
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: MTHFD1L)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	MTHFD1L	ENSG00000120254.15	24.91	26.54	25.73	ENCSR000AEF
HepG2	MTHFD1L	ENSG00000120254.15	26.19	39.12	32.66	ENCSR985KAT
K562	MTHFD1L	ENSG00000120254.15	49.30	44.07	46.69	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for MTHFD1L is not avaliable on ENCORE database.

Proteins bound to RNA

MTHFD1L RNA is bound by 36 proteins.

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eCLIP assay for MTHFD1L is not avaliable on ENCORE database.

36 proteins are bound to MTHFD1L RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr6	151310926	151310995	+	intron-Distal	5.99096	15.06634	HepG2	QKI
chr6	151186840	151186934	+	5'-UTR	4.31778	13.71012	K562	PUM1
chr6	151206819	151206869	+	5'-UTR,CDS	4.64498	13.32408	HepG2	BCLAF1
chr6	151281483	151281551	+	CDS	4.81935	13.19925	HepG2	PPIG
chr6	151330940	151330990	+	CDS,intron-Proximal	3.89909	12.69317	HepG2	U2AF2
chr6	151286126	151286173	+	CDS	3.87716	11.74630	HepG2	PPIG
chr6	151187544	151187669	+	5'-UTR,intron-Distal	5.45353	11.35706	HepG2	CSTF2T
chr6	151186934	151187042	+	5'-UTR,CDS	3.16178	11.14234	K562	PUM1
chr6	151243367	151243439	+	CDS,intron-Proximal	3.13900	10.89712	K562	ZNF622
chr6	151208983	151209048	+	CDS,intron-Distal	4.47413	10.68105	HepG2	BCLAF1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 119 entries

eCLIP assay for MTHFD1L is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for MTHFD1L is not available on ENCORE database.
134 RBPs can affect the levels of MTHFD1L.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for MTHFD1L is not available on ENCORE database.

134 RBPs can affect the gene expression of MTHFD1L :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
MTHFD1L	ENSG00000120254.11	524.98410	1770.40810	-1.75370	55.14960	52.67400	K562	HNRNPC
MTHFD1L	ENSG00000120254.11	201.55440	741.94080	-1.88010	43.17910	41.64640	HepG2	TIAL1
MTHFD1L	ENSG00000120254.11	255.68120	868.73940	-1.76460	28.58060	26.82580	HepG2	SUPV3L1
MTHFD1L	ENSG00000120254.11	336.87440	1020.06610	-1.59840	25.90910	24.00220	HepG2	EIF4A3
MTHFD1L	ENSG00000120254.11	331.91380	1773.91930	-2.41810	25.14060	23.94060	HepG2	SSB
MTHFD1L	ENSG00000120254.11	1677.70690	3593.69320	-1.09900	25.03450	23.45810	K562	AQR
MTHFD1L	ENSG00000120254.11	1398.31560	2608.67760	-0.89960	21.80150	20.02320	K562	UPF1
MTHFD1L	ENSG00000120254.11	379.83820	796.87940	-1.06900	20.42590	18.98370	HepG2	DKC1
MTHFD1L	ENSG00000120254.11	2676.89890	4356.41850	-0.70260	21.24620	18.72690	K562	PUM2
MTHFD1L	ENSG00000120254.11	315.01840	768.54730	-1.28670	19.32980	17.66350	HepG2	HNRNPC
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 178 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for MTHFD1L is not available on ENCORE database.

13 RBPs can affect the splicing of MTHFD1L :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	MTHFD1L	ENSG00000120254.11	chr6	+	151420635	151420793			151413602	151413723	151422661	151423023	0.47300	0.00000	0.00003	included	HepG2	U2AF1
SE	MTHFD1L	ENSG00000120254.11	chr6	+	151328686	151328917			151293083	151293194	151330954	151331094	0.30800	0.00000	0.00000	included	HepG2	U2AF2
A3SS	MTHFD1L	ENSG00000120254.11	chr6	+	151358072	151358253			151358100	151358253	151355667	151355736	0.07900	0.00000	0.00000	longer	K562	AQR
MXE	MTHFD1L	ENSG00000120254.11	chr6	+	151206769	151206870	151208977	151209117	151203897	151204022	151226785	151226897	-0.09000	0.00001	0.00077	2included	K562	DROSHA
MXE	MTHFD1L	ENSG00000120254.11	chr6	+	151206769	151206870	151208980	151209117	151203897	151204022	151226785	151226897	-0.09000	0.00001	0.00057	2included	K562	DROSHA
MXE	MTHFD1L	ENSG00000120254.11	chr6	+	151208977	151209117	151226785	151226897	151206769	151206870	151239712	151239804	0.20000	0.00001	0.00139	1included	K562	UTP18
MXE	MTHFD1L	ENSG00000120254.11	chr6	+	151208977	151209117	151226785	151226897	151206769	151206870	151239712	151239804	0.19500	0.00002	0.00070	1included	K562	PUS1
MXE	MTHFD1L	ENSG00000120254.11	chr6	+	151206769	151206870	151208977	151209117	151203897	151204022	151226785	151226897	-0.12300	0.00010	0.00283	2included	K562	SRSF1
MXE	MTHFD1L	ENSG00000120254.11	chr6	+	151208977	151209117	151226785	151226897	151206769	151206870	151239712	151239804	0.16500	0.00013	0.00698	1included	K562	RBM15
MXE	MTHFD1L	ENSG00000120254.11	chr6	+	151208980	151209117	151226785	151226897	151206769	151206870	151239712	151239804	0.17100	0.00015	0.01466	1included	K562	UTP18

Showing 1 to 10 of 21 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

MTHFD1L

General Information

Functions

Localization

Domains (AlphaFold: MTHFD1L)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for MTHFD1L is not avaliable on ENCORE database.

36 proteins are bound to MTHFD1L RNA:

eCLIP assay for MTHFD1L is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for MTHFD1L is not available on ENCORE database.

134 RBPs can affect the gene expression of MTHFD1L :

The Knockdown/knockout RNA-Seq assay for MTHFD1L is not available on ENCORE database.

13 RBPs can affect the splicing of MTHFD1L :

The Knockdown/knockout RNA-Seq assay for MTHFD1L is not avaliable on ENCORE database.