GLS

General Information

Gene Name : GLS
Gene ID : ENSG00000115419.12
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: GLS)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	GLS	ENSG00000115419.12	60.67	50.10	55.39	ENCSR000AEF
HepG2	GLS	ENSG00000115419.12	57.55	76.11	66.83	ENCSR985KAT
K562	GLS	ENSG00000115419.12	23.02	24.68	23.85	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for GLS is not avaliable on ENCORE database.

Proteins bound to RNA

GLS RNA is bound by 33 proteins.

CanvasJS.com

eCLIP assay for GLS is not avaliable on ENCORE database.

33 proteins are bound to GLS RNA:

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Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr2	191761287	191761376	+	intron-Distal	4.56411	71.08990	HepG2	U2AF2
chr2	191774987	191775049	+	CDS,intron-Proximal	4.90178	46.51690	HepG2	BCLAF1
chr2	191766682	191766755	+	CDS,intron-Proximal	3.97357	34.39681	HepG2	BCLAF1
chr2	191769782	191769877	+	CDS	4.56862	33.97531	HepG2	BCLAF1
chr2	191765314	191765410	+	CDS	4.23717	30.86684	HepG2	BCLAF1
chr2	191761624	191761721	+	intron-Distal	5.02761	29.49128	K562	KHSRP
chr2	191785870	191785933	+	3'-UTR,CDS,intron-Proximal	5.71574	28.74712	HepG2	BCLAF1
chr2	191776749	191776847	+	intron-Distal	5.60042	27.07342	HepG2	HNRNPL
chr2	191746243	191746328	+	intron-Distal,intron-Proximal	3.92421	26.69797	HepG2	EFTUD2
chr2	191769877	191769895	+	CDS,intron-Proximal	4.97685	26.58749	HepG2	BCLAF1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 182 entries

eCLIP assay for GLS is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for GLS is not available on ENCORE database.
133 RBPs can affect the levels of GLS.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for GLS is not available on ENCORE database.

133 RBPs can affect the gene expression of GLS :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
GLS	ENSG00000115419.8	771.02120	2981.78230	-1.95130	75.21170	72.86120	HepG2	HNRNPA1
GLS	ENSG00000115419.8	9145.29830	4368.08210	1.06590	52.58280	50.88220	HepG2	RBM22
GLS	ENSG00000115419.8	1991.00080	4283.70680	-1.10540	52.07940	50.54100	HepG2	SSB
GLS	ENSG00000115419.8	1030.02070	3201.73750	-1.63620	51.31930	49.66820	HepG2	TIAL1
GLS	ENSG00000115419.8	8512.06650	4933.65850	0.78680	43.64670	42.28210	HepG2	SRFBP1
GLS	ENSG00000115419.8	1638.39670	3294.66720	-1.00780	36.29080	34.32270	HepG2	HNRNPU
GLS	ENSG00000115419.8	1393.04450	2708.97460	-0.95950	35.55540	33.63270	HepG2	SRSF7
GLS	ENSG00000115419.8	16093.91430	2477.21700	2.69960	34.08230	31.90900	HepG2	RAVER1
GLS	ENSG00000115419.8	1618.96540	2927.12670	-0.85440	29.91000	27.99760	HepG2	DNAJC2
GLS	ENSG00000115419.8	1486.72290	3316.58750	-1.15760	29.97010	27.98080	HepG2	HNRNPC
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 166 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for GLS is not available on ENCORE database.

16 RBPs can affect the splicing of GLS :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	GLS	ENSG00000115419.8	chr2	+	191789268	191789319	191788642	191788709	191792031	191792208	-0.19900	0.00000	0.00000	excluded	HepG2	U2AF2
SE	GLS	ENSG00000115419.8	chr2	+	191777918	191778090	191774988	191775047	191785749	191785782	0.08900	0.00001	0.00233	included	HepG2	QKI
SE	GLS	ENSG00000115419.8	chr2	+	191819480	191819544	191819309	191819386	191827555	191830278	-0.29000	0.00002	0.00115	excluded	HepG2	SF3A3
SE	GLS	ENSG00000115419.8	chr2	+	191777918	191778090	191774988	191775047	191785749	191785782	0.07800	0.00003	0.01666	included	HepG2	ILF3
SE	GLS	ENSG00000115419.8	chr2	+	191777918	191778090	191774988	191775047	191785749	191785782	0.08800	0.00003	0.01039	included	HepG2	TIA1
SE	GLS	ENSG00000115419.8	chr2	+	191788642	191788709	191785870	191785929	191792031	191792337	-0.11500	0.00004	0.00076	excluded	K562	AQR
SE	GLS	ENSG00000115419.8	chr2	+	191777918	191778090	191774988	191775047	191785749	191785782	0.10800	0.00016	0.02129	included	HepG2	SUPV3L1
SE	GLS	ENSG00000115419.8	chr2	+	191819480	191819544	191819309	191819386	191827555	191830278	-0.32100	0.00025	0.02909	excluded	HepG2	PRPF8
SE	GLS	ENSG00000115419.8	chr2	+	191784940	191784974	191774988	191775047	191785749	191785782	0.09800	0.00043	0.02214	included	HepG2	HNRNPU
SE	GLS	ENSG00000115419.8	chr2	+	191789268	191789319	191788642	191788709	191792031	191792208	-0.08700	0.00104	0.02116	excluded	HepG2	U2AF1

Showing 1 to 10 of 16 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

GLS

General Information

Functions

Localization

Domains (AlphaFold: GLS)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for GLS is not avaliable on ENCORE database.

33 proteins are bound to GLS RNA:

eCLIP assay for GLS is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for GLS is not available on ENCORE database.

133 RBPs can affect the gene expression of GLS :

The Knockdown/knockout RNA-Seq assay for GLS is not available on ENCORE database.

16 RBPs can affect the splicing of GLS :

The Knockdown/knockout RNA-Seq assay for GLS is not avaliable on ENCORE database.