TMC6

General Information

Gene Name : TMC6
Gene ID : ENSG00000141524.15
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: TMC6)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	TMC6	ENSG00000141524.15	1.25	13.58	7.42	ENCSR000AEF
HepG2	TMC6	ENSG00000141524.15	51.34	8.22	29.78	ENCSR985KAT
K562	TMC6	ENSG00000141524.15	63.20	24.61	43.91	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for TMC6 is not avaliable on ENCORE database.

Proteins bound to RNA

TMC6 RNA is bound by 71 proteins.

CanvasJS.com

eCLIP assay for TMC6 is not avaliable on ENCORE database.

71 proteins are bound to TMC6 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr17	76119606	76119694	-	intron-Distal	7.45284	400.00000	K562	AGGF1
chr17	76119933	76119953	-	intron-Distal	7.18777	400.00000	K562	AGGF1
chr17	76119538	76119551	-	intron-Distal	6.90457	400.00000	K562	AGGF1
chr17	76119409	76119448	-	intron-Distal	8.13236	400.00000	K562	AGGF1
chr17	76119953	76120001	-	intron-Distal,intron-Proximal	6.81679	400.00000	K562	AGGF1
chr17	76119360	76119392	-	intron-Distal	8.12776	400.00000	K562	AGGF1
chr17	76119879	76119933	-	intron-Distal	6.42576	400.00000	K562	AGGF1
chr17	76119463	76119479	-	intron-Distal	7.35459	400.00000	K562	AGGF1
chr17	76119505	76119538	-	intron-Distal	7.31597	400.00000	K562	AGGF1
chr17	76119392	76119404	-	intron-Distal	8.54246	222.57316	K562	AGGF1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 689 entries

eCLIP assay for TMC6 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for TMC6 is not available on ENCORE database.
131 RBPs can affect the levels of TMC6.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for TMC6 is not available on ENCORE database.

131 RBPs can affect the gene expression of TMC6 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
TMC6	ENSG00000141524.11	327.10190	2011.72080	-2.62060	111.21910	109.23930	HepG2	SSB
TMC6	ENSG00000141524.11	468.64740	1946.24300	-2.05410	108.80880	106.33540	HepG2	DKC1
TMC6	ENSG00000141524.11	682.61810	2072.03340	-1.60190	87.15230	84.75940	HepG2	PUS1
TMC6	ENSG00000141524.11	681.47960	1881.40680	-1.46510	75.24490	72.55660	HepG2	DDX19B
TMC6	ENSG00000141524.11	2248.59720	877.65070	1.35720	74.97260	72.23050	HepG2	DAZAP1
TMC6	ENSG00000141524.11	1674.22390	551.10790	1.60300	71.52500	69.22800	HepG2	TRIM56
TMC6	ENSG00000141524.11	1910.53380	500.59040	1.93220	50.66340	48.44700	HepG2	SAFB2
TMC6	ENSG00000141524.11	1996.97400	816.26750	1.29060	48.78720	46.77540	HepG2	CELF1
TMC6	ENSG00000141524.11	2768.49050	1355.84880	1.02980	43.50410	41.44300	HepG2	UPF1
TMC6	ENSG00000141524.11	1673.51640	796.60120	1.07090	41.08220	39.06110	HepG2	SLBP
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 155 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for TMC6 is not available on ENCORE database.

53 RBPs can affect the splicing of TMC6 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
SE	TMC6	ENSG00000141524.11	chr17	-	76116733	76116913	76115377	76115473	76117093	76117245	-0.20600	0.00000	excluded	K562	SRSF1
SE	TMC6	ENSG00000141524.11	chr17	-	76120969	76121066	76120604	76120862	76121238	76121344	-0.55900	0.00000	excluded	HepG2	U2AF1
SE	TMC6	ENSG00000141524.11	chr17	-	76116733	76116913	76115377	76115473	76117093	76117245	-0.36200	0.00000	excluded	K562	PCBP1
SE	TMC6	ENSG00000141524.11	chr17	-	76116733	76116913	76115377	76115473	76117093	76117245	-0.20900	0.00008	excluded	K562	FMR1
SE	TMC6	ENSG00000141524.11	chr17	-	76113882	76114016	76113548	76113725	76115051	76115127	-0.07800	0.00005	excluded	K562	AQR
SE	TMC6	ENSG00000141524.11	chr17	-	76120969	76121066	76120638	76120862	76121238	76121344	-0.14200	0.00088	excluded	K562	APOBEC3C
SE	TMC6	ENSG00000141524.11	chr17	-	76116733	76116913	76115377	76115473	76117093	76117245	-0.26400	0.00000	excluded	HepG2	SRSF1
SE	TMC6	ENSG00000141524.11	chr17	-	76116733	76116913	76115377	76115473	76117093	76117245	-0.18900	0.00016	excluded	HepG2	IGF2BP3
SE	TMC6	ENSG00000141524.11	chr17	-	76116733	76116913	76115377	76115473	76117093	76117245	-0.50200	0.00000	excluded	HepG2	PCBP1
SE	TMC6	ENSG00000141524.11	chr17	-	76116733	76116913	76115377	76115473	76117093	76117245	0.16400	0.00020	included	HepG2	BCCIP

Showing 1 to 10 of 112 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

TMC6

General Information

Functions

Localization

Domains (AlphaFold: TMC6)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for TMC6 is not avaliable on ENCORE database.

71 proteins are bound to TMC6 RNA:

eCLIP assay for TMC6 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for TMC6 is not available on ENCORE database.

131 RBPs can affect the gene expression of TMC6 :

The Knockdown/knockout RNA-Seq assay for TMC6 is not available on ENCORE database.

53 RBPs can affect the splicing of TMC6 :

The Knockdown/knockout RNA-Seq assay for TMC6 is not avaliable on ENCORE database.