ZNF586

General Information

Gene Name       : ZNF586
Gene ID             : ENSG00000083828.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: ZNF586)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ZNF586ENSG00000083828.1511.8211.0911.46ENCSR000AEF
HepG2ZNF586ENSG00000083828.150.621.000.81ENCSR985KAT
K562ZNF586ENSG00000083828.156.675.676.17ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ZNF586 is not avaliable on ENCORE database.



Proteins bound to RNA
  • ZNF586 RNA is bound by 11 proteins.  







eCLIP assay for ZNF586 is not avaliable on ENCORE database.





11 proteins are bound to ZNF586 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr195833112358331223+3'-UTR,5'-UTR3.642863.10693HepG2UCHL5
chr195833109558331180+3'-UTR,5'-UTR3.714254.84938K562DDX3X
chr195833112358331218+3'-UTR,5'-UTR4.104704.66021K562GEMIN5
chr195833127858331319+3'-UTR,5'-UTR,CDS,intron-Proximal5.245404.35676HepG2PRPF8
chr195828107558281169+5'-UTR3.881683.15006K562RBM15
chr195828105858281178+5'-UTR4.303784.07395K562SRSF1
chr195831506958315130+intron-Distal3.993073.72005K562MATR3
chr195831507658315116+intron-Distal3.899074.22415K562PTBP1
chr195831489358314976+intron-Distal4.105505.36899HepG2PTBP1
chr195829777758297869+intron-Distal3.933936.89315K562SLTM
chr195832423758324417+intron-Distal3.628855.34807K562ILF3
chr195831484958314961+intron-Distal4.617035.04209K562MATR3
chr195831488358314965+intron-Distal6.6805412.52551K562PTBP1
chr195829999858300117+intron-Distal3.302483.24890K562SAFB2
chr195831482558314883+intron-Distal5.887057.91717K562PTBP1
chr195829800158298100+intron-Distal4.479168.80659K562SLTM
chr195831480758314893+intron-Distal3.766367.32475HepG2PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ZNF586 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ZNF586 is not available on ENCORE database.

  • 30 RBPs can affect the levels of ZNF586.  








The Knockdown/knockout RNA-Seq assay for ZNF586 is not available on ENCORE database.





30 RBPs can affect the gene expression of ZNF586 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ZNF586ENSG00000083828.1122.5070050.08930-1.154101.904001.45280HepG2AKAP1
ZNF586ENSG00000083828.1111.2959030.85260-1.449602.188901.44600HepG2EWSR1
ZNF586ENSG00000083828.1115.8366041.50460-1.390002.235601.60290HepG2HNRNPK
ZNF586ENSG00000083828.1183.3362039.054601.093403.220702.49790HepG2HNRNPL
ZNF586ENSG00000083828.118.2363028.59300-1.795602.023601.49510HepG2HNRNPU
ZNF586ENSG00000083828.1120.3759042.50430-1.060702.056301.39640HepG2NOL12
ZNF586ENSG00000083828.1140.7507017.510101.218502.275001.56600HepG2PRPF4
ZNF586ENSG00000083828.1126.1191049.62600-0.926001.765301.30880HepG2PTBP1
ZNF586ENSG00000083828.1124.3473055.23220-1.181702.465701.94990HepG2NELFE
ZNF586ENSG00000083828.1117.2047051.67410-1.586603.586302.92550HepG2SF3B4
ZNF586ENSG00000083828.1114.2137053.93370-1.923904.565203.99570HepG2SRSF1
ZNF586ENSG00000083828.1116.2751045.55030-1.484803.466102.78520HepG2SUCLG1
ZNF586ENSG00000083828.1112.4358032.84150-1.401001.982101.45750HepG2UTP3
ZNF586ENSG00000083828.11363.40950251.919600.528502.926902.25440K562AKAP8L
ZNF586ENSG00000083828.11249.05110375.39290-0.592003.480502.83800K562AQR
ZNF586ENSG00000083828.11333.39230213.611000.642104.409503.05900K562HNRNPA1
ZNF586ENSG00000083828.11119.84230179.42580-0.582302.044201.52020K562HNRNPC
ZNF586ENSG00000083828.11460.87660256.183600.847108.191306.28850K562HNRNPL
ZNF586ENSG00000083828.11181.86120259.38790-0.512302.588701.44850K562IGF2BP3
ZNF586ENSG00000083828.11182.08340268.11520-0.558303.031502.15130K562MAGOH
ZNF586ENSG00000083828.11181.52910261.99980-0.529402.747001.40180K562PCBP1
ZNF586ENSG00000083828.11130.22350226.64490-0.799403.769202.79790K562PCBP3
ZNF586ENSG00000083828.11111.00890173.84080-0.647102.551901.78540K562POLR2G
ZNF586ENSG00000083828.11103.11490160.85960-0.641502.317801.49610K562PSIP1
ZNF586ENSG00000083828.11334.69800450.59340-0.429002.972801.98050K562PUM2
ZNF586ENSG00000083828.11353.32920249.875000.499702.576802.04860K562PUS1
ZNF586ENSG00000083828.11180.63730262.91760-0.541502.587401.53470K562NELFE
ZNF586ENSG00000083828.1163.25120121.97530-0.947403.007601.99240K562SF3B1
ZNF586ENSG00000083828.1194.16780236.62350-1.3293011.138009.35600K562SF3B4
ZNF586ENSG00000083828.11115.24590255.33550-1.147708.455007.22420K562SRSF1
ZNF586ENSG00000083828.11143.60780237.18910-0.723903.754101.87920K562TBRG4
ZNF586ENSG00000083828.11161.67220244.53890-0.597002.725301.64270K562TRA2A
ZNF586ENSG00000083828.11105.40600164.30150-0.640402.288901.44160K562TRIM56
ZNF586ENSG00000083828.11328.36100444.73080-0.437602.737201.45620K562WRN
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ZNF586 is not available on ENCORE database.





7 RBPs can affect the splicing of ZNF586 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEZNF586ENSG00000083828.11chr19+5828791058288037582810375828124658290118582919820.499000.000260.05842includedK562FTO
SEZNF586ENSG00000083828.11chr19+582879105828803758281037582812465829011858291982-0.260000.001570.04475excludedK562AKAP8L
SEZNF586ENSG00000083828.11chr19+5828791058288037582810375828124658290118582919820.665000.000020.00404includedK562FMR1
SEZNF586ENSG00000083828.11chr19+582879105828803758281037582812465829011858291982-0.245000.001220.02009excludedK562PUS1
SEZNF586ENSG00000083828.11chr19+582879105828804258281037582812465829011858291912-0.245000.001260.07579excludedK562HNRNPL
SEZNF586ENSG00000083828.11chr19+582879105828803758281037582812465829011858291982-0.256000.003160.07962excludedK562UTP18
SEZNF586ENSG00000083828.11chr19+582879105828803758281037582812465829011858291982-0.359000.000030.00180excludedK562AGGF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ZNF586 is not avaliable on ENCORE database.